H. England

发表

Integration of Kinase and Calcium Signaling at the Level of Chromatin Underlies Inducible Gene Activation in T Cells

Nigel P. Dyer, S. Ott, A. Pisco, 2017, The Journal of Immunology.

Macrophage-Specific NF-κB Activation Dynamics Can Segregate Inflammatory Bowel Disease Patients

M. White, P. Paszek, D. Jackson, 2019, bioRxiv.

Zinc depletion regulates the processing and secretion of IL-1β

P. Mendes, J. Pahle, G. López-Castejón, 2014, Cell Death and Disease.

Gene-Specific Linear Trends Constrain Transcriptional Variability of the Toll-like Receptor Signaling

Mark R. Muldoon, M. Platt, P. Paszek, 2020, Cell systems.

Using systems medicine to identify a therapeutic agent with potential for repurposing in inflammatory bowel disease

V. Poroikov, V. M. D. Martins dos Santos, A. Kel, 2019, Disease Models & Mechanisms.

Identification of a novel therapeutic agent for Inflammatory Bowel Disease guided by systems medicine

V. Poroikov, A. Kel, D. Spiller, 2019 .

Macrophage-Specific NF-κB Activation Dynamics Can Segregate Inflammatory Bowel Disease Patients

V. M. D. Martins dos Santos, D. Spiller, M. White, 2019, Frontiers in immunology.

Release of Interleukin-1α or Interleukin-1β Depends on Mechanism of Cell Death*

N. Rothwell, D. Brough, H. England, 2014, The Journal of Biological Chemistry.

Using systems medicine to identify a therapeutic agent with potential for repurposing in Inflammatory Bowel Disease

V. Poroikov, A. Kel, D. Spiller, 2019, bioRxiv.

Boron-Based Inhibitors of the NLRP3 Inflammasome

N. Rothwell, D. Brough, S. Allan, 2017, Cell chemical biology.

Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation

D. Spiller, M. White, R. Brignall, 2018, Science Signaling.

Effects of Human RelA Transgene on Murine Macrophage Inflammatory Responses

P. Rosenstiel, V. M. D. Martins dos Santos, Lorna Morris, 2022, Biomedicines.

Overexpression of IκB⍺ modulates NF-κB activation of inflammatory target gene expression

D. Spiller, P. Paszek, D. Jackson, 2023, bioRxiv.

Boron-Based Inhibitors of the NLRP 3 Inflammasome Graphical Abstract Highlights

N. Rothwell, D. Brough, S. Allan, 2022 .

Anti‐inflammatory effects of infliximab in mice are independent of tumour necrosis factor α neutralization

J. Mclaughlin, P. Paszek, J. Bagnall, 2016, Clinical and experimental immunology.

Release of IL-1alpha or IL-1beta depends on mechanism of cell death

N. Rothwell, D. Brough, H. England, 2014 .

Integration of Kinase and Calcium Signaling at the Level of Chromatin Underlies Inducible Gene Activation in T Cells

Nigel P. Dyer, S. Ott, A. Pisco, 2017, The Journal of Immunology.

Identification of a novel therapeutic agent for Inflammatory Bowel Disease guided by systems medicine One sentence summary: Novel bioinformatic analyses and laboratory validation demonstrate the anti-inflammatory effects of clarithromycin and suggest that it may be repositioned for the management of

V. Poroikov, A. Kel, D. Spiller, 2019 .