Xinxin Huang

发表

ADGRG1 enriches for functional human hematopoietic stem cells following ex vivo expansion-induced mitochondrial oxidative stress.

H. Broxmeyer, J. Wan, Yandan Chen, 2021, The Journal of clinical investigation.

Past, present, and future efforts to enhance the efficacy of cord blood hematopoietic cell transplantation

H. Broxmeyer, Xinxin Huang, Maegan L Capitano, 2019, F1000Research.

Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock

M. Ivan, N. Bardeesy, H. Broxmeyer, 2015, Cell.

MicroRNA-124 Targets Tip110 Expression and Regulates Hematopoiesis.

K. Timani, Johnny J. He, H. Broxmeyer, 2015, Stem cells and development.

Antagonism of PPAR-γ signaling expands human hematopoietic stem and progenitor cells by enhancing glycolysis

H. Broxmeyer, Xinxin Huang, Bin Guo, 2018, Nature Medicine.

Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signaling.

D. Markovitz, N. Mor-Vaknin, H. Broxmeyer, 2019, The Journal of clinical investigation.

CD166 Engagement Augments Mouse and Human Hematopoietic Progenitor Function via Activation of Stemness and Cell Cycle Pathways

H. Broxmeyer, S. Cooper, E. Srour, 2019, Stem cells.

Cutting Edge: Progesterone Directly Upregulates Vitamin D Receptor Gene Expression for Efficient Regulation of T Cells by Calcitriol

H. Broxmeyer, Chang H. Kim, J. Cho, 2015, The Journal of Immunology.

Expansion of Human Megakaryocyte-Lineage Progeny via Aryl Hydrocarbon Receptor Antagonism with CH223191

Junshik Hong, H. Broxmeyer, Sung-Soo Yoon, 2022, Stem Cell Reviews and Reports.

Update on preclinical and clinical efforts on ex-vivo expansion of hematopoietic stem and progenitor cells

Xinxin Huang, Bin Guo, 2022, Current opinion in hematology.

Effects of Eupalinilide E and UM171, alone and in combination on cytokine stimulated ex-vivo expansion of human cord blood hematopoietic stem cells.

D. Siegel, H. Broxmeyer, S. Cooper, 2020, Blood cells, molecules & diseases.

Phorbol ester induced ex vivo expansion of rigorously-defined phenotypic but not functional human cord blood hematopoietic stem cells: a cautionary tale demonstrating that phenotype does not always recapitulate stem cell function

H. Broxmeyer, J. Wan, Yandan Chen, 2019, Leukemia.

Progress towards improving homing and engraftment of hematopoietic stem cells for clinical transplantation.

H. Broxmeyer, Xinxin Huang, 2019, Current opinion in hematology.

Glucocorticoid hormone-induced chromatin remodeling enhances human hematopoietic stem cell homing and engraftment

H. Broxmeyer, S. Cooper, Xinxin Huang, 2017, Nature Medicine.

Pharmacological activation of nitric oxide signaling promotes human hematopoietic stem cell homing and engraftment

H. Broxmeyer, J. Wan, Xinxin Huang, 2020, Leukemia.

Chromatin remodeling subunit BRM and valine regulate hematopoietic stem/progenitor cell function and self-renewal via intrinsic and extrinsic effects

H. Broxmeyer, S. Cooper, Xinxin Huang, 2021, Leukemia.

Mitigating oxygen stress enhances aged mouse hematopoietic stem cell numbers and function.

Christie M. Orschell, H. Broxmeyer, S. Cooper, 2021, The Journal of clinical investigation.

m6A reader suppression bolsters HSC expansion

H. Broxmeyer, Xinxin Huang, 2018, Cell Research.

Phosphatidylinositol transfer proteins regulate megakaryocyte TGF-β1 secretion and hematopoiesis in mice.

M. Marks, H. Broxmeyer, A. Dent, 2018, Blood.

SIRT1 Positively Regulates Autophagy and Mitochondria Function in Embryonic Stem Cells Under Oxidative Stress

H. Broxmeyer, Steven Messina-Graham, Xinxin Huang, 2014, Stem cells.

Specific mesoderm subset derived from human pluripotent stem cells ameliorates microvascular pathology in type 2 diabetic mice

M. Boulton, S. L. Calzi, D. Kotton, 2022, Science advances.

Activation of OCT4 enhances ex vivo expansion of human cord blood hematopoietic stem and progenitor cells by regulating HOXB4 expression

H. Broxmeyer, G. Hangoc, S. Cooper, 2015, Leukemia.

Enhancing human cord blood hematopoietic stem cell engraftment by targeting nuclear hormone receptors

H. Broxmeyer, Xinxin Huang, Bin Guo, 2018, Current opinion in hematology.

Hypoxia Signaling Pathway in Stem Cell Regulation: Good and Evil

H. Broxmeyer, Xinxin Huang, Arafat Aljoufi, 2018, Current Stem Cell Reports.

The importance of hypoxia and extra physiologic oxygen shock/stress for collection and processing of stem and progenitor cells to understand true physiology/pathology of these cells ex vivo

H. Broxmeyer, C. Mantel, Xinxin Huang, 2015, Current opinion in hematology.

Neutralizing negative epigenetic regulation by HDAC5 enhances human haematopoietic stem cell homing and engraftment

H. Broxmeyer, J. Wan, Xinxin Huang, 2018, Nature Communications.

Combinations of antioxidants and/or of epigenetic enzyme inhibitors allow for enhanced collection of mouse bone marrow hematopoietic stem cells in ambient air.

H. Broxmeyer, S. Cooper, Xinxin Huang, 2018, Blood cells, molecules & diseases.

Neutralizing negative epigenetic regulation by HDAC5 enhances human haematopoietic stem cell homing and engraftment

H. Broxmeyer, J. Wan, Xinxin Huang, 2018, Nature Communications.

miRNA regulation of Tip110 expression and self-renewal and differentiation of human CD34+ hematopoietic cells

K. Timani, Johnny J. He, H. Broxmeyer, 2017, Oncotarget.

Physioxia enhances T‐cell development ex vivo from human hematopoietic stem and progenitor cells

H. Broxmeyer, Dong-Yeop Shin, Xinxin Huang, 2020, Stem cells.

Hypoxia Signaling Pathway in Stem Cell Regulation: Good and Evil

H. Broxmeyer, Xinxin Huang, Arafat Aljoufi, 2018, Current Stem Cell Reports.

In memory of Hal E. Broxmeyer, a pluripotent scientist, pioneer, and mentor

Linzhao Cheng, Xinxin Huang, Bin Guo, 2022, Blood science.

Patient-Tailored Mouse Genome Editing Recapitulates Hematopoietic and Systemic Manifestations of Barth Syndrome

H. Broxmeyer, G. Nalepa, Xinxin Huang, 2017 .

Phosphatidylinositol transfer proteins regulate megakaryocyte TGF-β1 secretion and hematopoiesis in mice.

M. Marks, H. Broxmeyer, A. Dent, 2018, Blood.

m6A reader suppression bolsters HSC expansion

H. Broxmeyer, Xinxin Huang, 2018, Cell Research.