H. van den Elst

发表

Use of shuttle vectors to study the molecular processing of defined carcinogen-induced DNA damage: mutagenicity of single O4-ethylthymine adducts in HeLa cells.

G. A. van der Marel, A. Berns, H. Elst, 1990, Nucleic acids research.

A dot-blot screening procedure for mutated ras oncogenes using synthetic oligodeoxynucleotides.

J. Bos, M. V. Vries, A. van der Eb, 1986, Gene.

Development of a Retinal-Based Probe for the Profiling of Retinaldehyde Dehydrogenases in Cancer Cells

Sylvia E. Le Dévédec, H. Overkleeft, G. V. van Westen, 2019, ACS central science.

Comparing Cyclophellitol N-Alkyl and N-Acyl Cyclophellitol Aziridines as Activity-Based Glycosidase Probes.

H. Overkleeft, G. A. van der Marel, J. Jiang, 2015, Chemistry.

Novel activity-based probes for broad-spectrum profiling of retaining β-exoglucosidases in situ and in vivo.

G. A. van der Marel, J. Jiang, M. Witte, 2012, Angewandte Chemie.

Synthesis and biological evaluation of modified DNA fragments for the study of nucleotide excision repair in E. coli.

G. A. van der Marel, R. Visse, J. V. van Boom, 1999, Nucleosides & nucleotides.

Improvement of Hepatocyte‐Specific Gene Expression by a Targeted Colchicine Prodrug

G. A. van der Marel, G. Koning, T. V. van Berkel, 2003, Chembiochem : a European journal of chemical biology.

Paenilamicin: structure and biosynthesis of a hybrid nonribosomal peptide/polyketide antibiotic from the bee pathogen Paenibacillus larvae.

H. Overkleeft, E. Genersch, Sebastian Y. Müller, 2014, Angewandte Chemie.

Comparative Photoaffinity Profiling of Omega-3 Signaling Lipid Probes Reveals Prostaglandin Reductase 1 as a Metabolic Hub in Human Macrophages

M. Giera, R. Toes, B. Florea, 2022, Journal of the American Chemical Society.

NMR studies of DNA three-way junctions containing two unpaired thymidine bases: the influence of the sequence at the junction on the stability of the stacking conformers.

F. J. Overmars, J. Pikkemaat, J. V. van Boom, 1996, Journal of molecular biology.

Thermodynamics of the various forms of the dodecamer d(ATTACCGGTAAT) and of its constituent hexamers from proton nmr chemical shifts and UV melting curves: Three‐state and four‐state thermodynamic models

G. A. van der Marel, J. V. van Boom, C. Altona, 1989, Biopolymers.

Synthesis and biological evaluation of lipophilic Ca(1)a(2)L analogues as potential bisubstrate inhibitors of protein:geranylgeranyl transferase-1.

H. Overkleeft, G. A. van der Marel, H. van den Elst, 2005, Bioorganic & medicinal chemistry.

Chemical synthesis of picornaviral protein primers of RNA replication.

D. Filippov, G. A. van der Marel, H. Heus, 2006, Organic & biomolecular chemistry.

Automated parallel solid-phase synthesis and anticancer screening of a library of peptide-tethered platinum(II) complexes.

G. A. van der Marel, M. Bacac, J. V. van Boom, 2003, Journal of combinatorial chemistry.

Design, synthesis, and evaluation of sugar amino acid based inhibitors of protein prenyl transferases PFT and PGGT-1.

H. Overkleeft, G. A. van der Marel, J. V. van Boom, 2004, Journal of medicinal chemistry.

Automated solid-phase synthesis of hyaluronan oligosaccharides.

H. Overkleeft, G. A. van der Marel, A. Volbeda, 2012, Organic letters.

Automated solid-phase synthesis of β-mannuronic acid alginates.

H. Overkleeft, G. A. van der Marel, P. Seeberger, 2012, Angewandte Chemie.

Systematic Dual Targeting of Dendritic Cell C-Type Lectin Receptor DC-SIGN and TLR7 Using a Trifunctional Mannosylated Antigen

D. Filippov, H. Overkleeft, G. A. van der Marel, 2019, Front. Chem..

Synthesis of isotope labeled oligonucleotides and their use in an NMR study of a protein-DNA complex.

M. L. Remerowski, G. A. van der Marel, R. Kaptein, 1992, Nucleic acids research.

Heteronuclear NMR of DNA with the heteronucleus in natural abundance: facilitated assignment and extraction of coupling constants.

P. Schmieder, G. A. van der Marel, H. Kessler, 1992, Nucleic acids research.

Repair and replication of plasmids with site-specific 8-oxodG and 8-AAFdG residues in normal and repair-deficient human cells.

G. A. van der Marel, M. Bleeker, J. V. van Boom, 1992, Nucleic acids research.

Solid-phase synthesis of DNA fragments containing the modified base 7-hydro-8-oxo-2'-deoxyguanosine.

G. A. van der Marel, J. V. van Boom, H. Brugghe, 1991, Nucleic acids research.

Solid-phase synthesis of a cell-wall component of Haemophilus (Actinobacillus) pleuropneumoniae serotype 2.

G. Veeneman, J. V. van Boom, H. Brugghe, 1990, Carbohydrate research.

Conformational and thermodynamic consequences of the introduction of a nick in duplexed DNA fragments: an NMR study augmented by biochemical experiments.

G. A. van der Marel, R. Mans, H. Elst, 1989, Nucleic acids research.

Tuning the Transglycosylation Reaction of a GH11 Xylanase by a Delicate Enhancement of its Thumb Flexibility

M. Ubbink, H. Overkleeft, H. van den Elst, 2020, bioRxiv.

Development of an activity-based probe and in silico design reveal highly selective inhibitors for diacylglycerol lipase-α in brain.

R. McGuire, H. Overkleeft, G. A. van der Marel, 2013, Angewandte Chemie.

Activity-based profiling reveals reactivity of the murine thymoproteasome-specific subunit beta5t.

H. Overkleeft, Keiji Tanaka, S. Murata, 2010, Chemistry & biology.

NMR studies and conformational analysis of a DNA four-way junction formed in a linear synthetic oligonucleotide.

J. Pikkemaat, J. V. van Boom, C. Altona, 1994, Biochemistry.

Role of nucleotide excision repair in processing of O4-alkylthymines in human cells.

G. A. van der Marel, G. Margison, M. Bleeker, 1994, The Journal of biological chemistry.

New Irreversible α‐l‐Iduronidase Inhibitors and Activity‐Based Probes

H. Overkleeft, G. A. van der Marel, M. Artola, 2018, Chemistry.

Solid-phase synthesis of an RNA nucleopeptide fragment from the nucleoprotein of poliovirus.

G. A. van der Marel, J. V. van Boom, C. Dreef‐Tromp, 1992, Nucleic acids research.

Biochemical and biophysical studies on the folding of the core region of the origin of replication of bacteriophage M13.

C. W. Hilbers, A. van Belkum, M. Blommers, 1990, Nucleic acids research.

Novel activity-based probes for broad-spectrum profiling of retaining β-exoglucosidases in situ and in vivo.

J. Jiang, M. Witte, B. Florea, 2012, Angewandte Chemie.

Automated solid-phase synthesis of β-mannuronic acid alginates.

H. Overkleeft, G. A. van der Marel, P. Seeberger, 2012, Angewandte Chemie.

Solid-phase synthesis of oligodeoxynucleotides containing 4-alkoxythymidine residues

J. H. Boom, H. Elst, J. V. van Boom, 2010 .