G. Santis

发表

Simultaneous FRAP, FLIM and FAIM for measurements of protein mobility and interaction in living cells.

P. Morton, M. Parsons, K. Suhling, 2015, Biomedical optics express.

Coxsackie adenovirus receptor (CAR) regulates integrin function through activation of p44/42 MAPK.

P. Morton, M. Parsons, G. Santis, 2009, Experimental cell research.

CAR Modulates E-Cadherin Dynamics in the Presence of Adenovirus Type 5

P. Morton, M. Martin-Fernandez, M. Parsons, 2011, PloS one.

The challenges of integrating molecular imaging into the optimization of cancer therapy.

V. Goh, P. Ellis, T. Schaeffter, 2011, Integrative biology : quantitative biosciences from nano to macro.

Suspicious for Malignancy (SFM)

S. Roy-Chowdhuri, G. Santis, P. Mikou, 2020 .

The ErbB4 CYT2 variant protects EGFR from ligand-induced degradation to enhance cancer cell motility

B. Kholodenko, A. Tutt, S. Pinder, 2014, Science Signaling.

Unilateral diffuse idiopathic pulmonary neuroendocrine cell hyperplasia and multiple carcinoids treated with surgical resection.

S. Irshad, E. Mclean, S. Barrington, 2010, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

The LungPath study: variation in the diagnostic and staging pathway for patients with lung cancer in England

M. Peake, P. Cane, H. Møller, 2015, Thorax.

Independent genetic determinants of pancreatic and pulmonary status in cystic fibrosis

M. Hodson, G. Santis, R. Knight, 1990, The Lancet.

Adenovirus Type 9 Fiber Knob Binds to the Coxsackie B Virus-Adenovirus Receptor (CAR) with Lower Affinity than Fiber Knobs of Other CAR-Binding Adenovirus Serotypes

B. Sutton, I. Kovesdi, T. Wickham, 2001, Journal of Virology.

A mutation in the second nucleotide binding fold of the cystic fibrosis gene.

M. Hodson, G. Santis, R. Knight, 1991, American journal of human genetics.

Plasmacytoid dendritic cells from human lung cancer draining lymph nodes induce Tc1 responses.

C. Hawrylowicz, G. Santis, D. Richards, 2007, American journal of respiratory cell and molecular biology.

Points: Low osmolar contrast media

G. Santis, D. Burd, 1984 .

Linked marker haplotypes and the ΔF508 mutation in adults with mild pulmonary disease and cystic fibrosis

M. Hodson, G. Santis, R. Knight, 1990, The Lancet.

The Human HLA-A*0201 Allele, Expressed in Hamster Cells, Is Not a High-Affinity Receptor for Adenovirus Type 5 Fiber

T. Elliott, I. Kirby, G. Santis, 1999, Journal of Virology.

Nasal epithelial ion transport and genetic analysis of infertile men with congenital bilateral absence of the vas deferens.

D. Geddes, M. Hodson, E. Alton, 1993, Human molecular genetics.

T6 MET targeted therapy in Lung adenocarcinoma: Does ‘Resistant’ EGFR make a MET-responsive dimer?

T. Ng, G. Fruhwirth, G. Weitsman, 2015 .

Integrin alpha5beta1-mediated adenovirus infection is enhanced by the integrin-activating antibody TS2/16

J. Marshall, I. Hart, G. Santis, 1997, Journal of virology.

Integrin a 5 b 1-Mediated Adenovirus Infection Is Enhanced by the Integrin-Activating Antibody TS 2 / 16

J. Marshall, I. Hart, G. Santis, 1997 .

Adenovirus type 5 uptake by lung adenocarcinoma cells in culture correlates with Ad5 fibre binding is mediated by αvβ1 integrin and can be modulated by changes in β1 integrin function

I. Kirby, I. Hart, G. Santis, 2001, Journal of Gene Medicine.

Epithelial coxsackievirus adenovirus receptor promotes house dust mite-induced lung inflammation

P. Mertins, M. Parsons, J. Rosenblatt, 2022, Nature Communications.

TNFα promotes CAR-dependent migration of leukocytes across epithelial monolayers

P. Morton, M. Parsons, G. Jenkins, 2016, Scientific Reports.

CAR: A key regulator of adhesion and inflammation.

M. Parsons, G. Santis, E. Ortiz-Zapater, 2017, The international journal of biochemistry & cell biology.

Severe extravasation injury

T. Milward, G. Santis, D. Burd, 1985 .

Routine EGFR and KRAS Mutation analysis using COLD‐PCR in non‐small cell lung cancer

J. Spicer, K. Tobal, P. Cane, 2012, International journal of clinical practice.

Severe extravasation injury: an avoidable iatrogenic disaster?

T. Milward, G. Santis, D. Burd, 1985, British medical journal.

Identification of Contact Residues and Definition of the CAR-Binding Site of Adenovirus Type 5 Fiber Protein

Andrew J. Beavil, Brian J. Sutton, A. Beavil, 2000, Journal of Virology.

Heterogeneity in the severity of cystic fibrosis and the role of CFTR gene mutations

Michael Dean, M. Dean, G. Santis, 1994, Human Genetics.

Challenges in molecular testing in non-small-cell lung cancer patients with advanced disease

C. Swanton, C. Hiley, J. L. Quesne, 2016, The Lancet.

Incidence and expression of the N1303K mutation of the cystic fibrosis (CFTR) gene

X. Estivill, K. Klinger, B. Kerem, 1992, Human Genetics.

MET-EGFR dimerization in lung adenocarcinoma is dependent on EGFR mtations and altered by MET kinase inhibition

P. Parker, T. Ng, G. Fruhwirth, 2017, PloS one.

Screening for EGFR and KRAS Mutations in Endobronchial Ultrasound Derived Transbronchial Needle Aspirates in Non-Small Cell Lung Cancer Using COLD-PCR

E. Mclean, J. Spicer, K. Tobal, 2011, PloS one.

KIF22 coordinates CAR and EGFR dynamics to promote cancer cell proliferation

M. Parsons, G. Santis, E. Ortiz-Zapater, 2018, Science Signaling.

Diagnosis and subtyping of de novo and relapsed mediastinal lymphomas by endobronchial ultrasound needle aspiration.

G. Santis, P. Fields, M. Moonim, 2013, American journal of respiratory and critical care medicine.

EBUS‐TBNA: an opportunity for clinicians, cytopathologists and patients to gain from multidisciplinary collaboration

A. Herbert, G. Santis, 2010, Cytopathology : official journal of the British Society for Clinical Cytology.

ALK rearrangements in EBUS‐derived transbronchial needle aspiration cytology in lung cancer

E. Mclean, M. Neat, G. Santis, 2013, Cytopathology : official journal of the British Society for Clinical Cytology.

CAR Co-Operates With Integrins to Promote Lung Cancer Cell Adhesion and Invasion

M. Parsons, G. Santis, E. Papaevangelou, 2022, Frontiers in Oncology.

Gene expression profiling of endobronchial ultrasound (EBUS)‐derived cytological fine needle aspirates from hilar and mediastinal lymph nodes in non‐small cell lung cancer

E. Mclean, G. Santis, R. Breen, 2013, Cytopathology : official journal of the British Society for Clinical Cytology.

Utility of endobronchial ultrasound-guided transbronchial needle aspiration in patients with tuberculous intrathoracic lymphadenopathy: a multicentre study

R. Rintoul, M. Nankivell, P. Molyneaux, 2011, Thorax.

Validation of Differentially Expressed Immune Biomarkers in Latent and Active Tuberculosis by Real-Time PCR

S. Sinha, S. Vasan, I. Honeyborne, 2021, Frontiers in Immunology.

The Transcriptional Signature of Active Tuberculosis Reflects Symptom Status in Extra-Pulmonary and Pulmonary Tuberculosis

V. Pascual, J. Banchereau, D. Chaussabel, 2016, PloS one.

A 380-gene meta-signature of active tuberculosis compared with healthy controls

J. Banchereau, D. Chaussabel, D. Blankenship, 2016, European Respiratory Journal.

Molecular determinants of adenovirus serotype 5 fibre binding to its cellular receptor CAR.

J. Bergelson, M. Mehtali, R. Finberg, 1999, The Journal of general virology.

Analysis of the interaction between RGD-expressing adenovirus type 5 fiber knob domains and alphavbeta3 integrin reveals distinct binding profiles and intracellular trafficking.

Maddy Parsons, James Hunt, Andrew Beavil, 2006, The Journal of general virology.

Mutations in the DG Loop of Adenovirus Type 5 Fiber Knob Protein Abolish High-Affinity Binding to Its Cellular Receptor CAR

A. Beavil, B. Sutton, I. Kovesdi, 1999, Journal of Virology.

CAR regulates epithelial cell junction stability through control of E-cadherin trafficking

P. Morton, M. Parsons, G. Santis, 2013, Scientific Reports.

High resolution computed tomography in adult cystic fibrosis patients with mild lung disease.

M. Hodson, G. Santis, B. Strickland, 1991, Clinical radiology.

Non-Small Cell Lung Cancer (NSCLC) in Young Adults, Age < 50, Is Associated with Late Stage at Presentation and a Very Poor Prognosis in Patients That Do Not Have a Targeted Therapy Option: A Real-World Study

E. Karapanagiotou, J. Spicer, D. Josephs, 2022, Cancers.

Temporospatial heterogeneity of acquired resistance mechanisms in EGFR-mutant lung adenocarcinoma: A case of concurrent EGFRT790M mutation and small cell transformation

E. Karapanagiotou, G. Cook, E. Mclean, 2021 .

Adenovirus type-5 entry and disassembly followed in living cells by FRET, fluorescence anisotropy, and FLIM.

M. Martin-Fernandez, D. Clarke, M. Tobin, 2004, Biophysical journal.

The architecture of EGFR’s basal complexes reveals autoinhibition mechanisms in dimers and oligomers

Laura C. Zanetti-Domingues, D. Shaw, Y. Shan, 2018, Nature Communications.

S57 Gene expression profiling of endobronchial ultrasound-derived cytological aspirates from hilar and mediastinal lymph nodes in NSCLC

G. Santis, R. Breen, E. McClean, 2011, Thorax.

Diagnosis and subclassification of thymoma by minimally invasive fine needle aspiration directed by endobronchial ultrasound: a review and discussion of four cases

G. Santis, M. Moonim, R. Breen, 2012, Cytopathology : official journal of the British Society for Clinical Cytology.

The architecture of EGFR’s basal complexes reveals autoinhibition mechanisms in dimers and oligomers

Laura C. Zanetti-Domingues, D. Shaw, F. Gervasio, 2018, Nature Communications.

KIF22 co-ordinates CAR and EGFR dynamics to promote cancer cell proliferation

M. Parsons, G. Santis, E. Ortiz-Zapater, 2018 .

Utility of endobronchial ultrasound-guided transbronchial needle aspiration in patients with tuberculous intrathoracic lymphadenopathy: a multicentre study

R. Rintoul, M. Nankivell, P. Molyneaux, 2011, Thorax.

The utility and safety of linear endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in the paediatric population

G. Santis, O. Narayan, R. Breen, 2020, European Respiratory Journal.

CAR: A key regulator of adhesion and inflammation.

M. Parsons, G. Santis, Elena Ortiz-Zapater, 2017, The international journal of biochemistry & cell biology.