G. Babu

发表

Regulation of sarcoplasmic reticulum Ca2+ ATPase pump expression and its relevance to cardiac muscle physiology and pathology.

M. Periasamy, Poornima Bhupathy, G. Babu, 2007, Cardiovascular research.

Differential vasoconstrictions induced by angiotensin II: role of AT1 and AT2 receptors in isolated C57BL/6J mouse blood vessels.

W. P. Dirksen, M. Periasamy, G. Babu, 2003, American journal of physiology. Heart and circulatory physiology.

Sarcoplasmic Reticulum Ca2+ ATPase (SERCA) 1a Structurally Substitutes for SERCA2a in the Cardiac Sarcoplasmic Reticulum and Increases Cardiac Ca2+ Handling Capacity

E. Marbán, R. Walsh, V. Prasad, 2001, Circulation research.

Decreased sarcolipin protein expression and enhanced sarco(endo)plasmic reticulum Ca2+ uptake in human atrial fibrillation.

R. Fischmeister, G. Babu, M. Shanmugam, 2011, Biochemical and biophysical research communications.

Disruption of a Single Copy of the SERCA2 Gene Results in Altered Ca2+ Homeostasis and Cardiomyocyte Function*

D L Kirkpatrick, R. Walsh, G. Shull, 2000, The Journal of Biological Chemistry.

Overexpression of sarcolipin decreases myocyte contractility and calcium transient.

M. Periasamy, G. Babu, P. Janssen, 2005, Cardiovascular research.

Overexpression of SERCA2b in the Heart Leads to an Increase in Sarcoplasmic Reticulum Calcium Transport Function and Increased Cardiac Contractility*

Mark A Sussman, I. Grupp, M. Periasamy, 2000, The Journal of Biological Chemistry.

Reducing sarcolipin expression mitigates Duchenne muscular dystrophy and associated cardiomyopathy in mice

J. McArdle, J. Mendell, Lai-Hua Xie, 2017, Nature Communications.

Ablation of sarcolipin enhances sarcoplasmic reticulum calcium transport and atrial contractility

N. Chiamvimonvat, M. Periasamy, Poornima Bhupathy, 2007, Proceedings of the National Academy of Sciences.

Sarcoplasmic reticulum calcium uptake and speed of relaxation are depressed in nebulin‐free skeletal muscle

C. Ottenheijm, H. Granzier, P. Vangheluwe, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Deletion of SM-B, the high ATPase isoform of myosin, upregulates the PKC-mediated signal transduction pathway in murine urinary bladder smooth muscle.

A. Wein, M. Periasamy, G. Babu, 2009, American journal of physiology. Renal physiology.

Deletion of SMB , the high ATPase isoform of myosin , upregulates the PKC-mediated signal transduction pathway in murine urinary bladder smooth muscle

A. Wein, M. Periasamy, G. Babu, 2009 .

Sarcolipin Knockdown Therapy for Duchenne Muscular Dystrophy

N. Niranjan, G. Babu, Satvik Mareedu, 2019, Muscle Gene Therapy.

H-Ras Isoform Mediates Protection Against Pressure Overload–Induced Cardiac Dysfunction in Part Through Activation of AKT

P. Zhai, G. Babu, S. Ikeda, 2017, Circulation. Heart failure.

Phosphorylation of elk-1 by MEK/ERK pathway is necessary for c-fos gene activation during cardiac myocyte hypertrophy.

Mark A Sussman, J. Sadoshima, M. Periasamy, 2000, Journal of molecular and cellular cardiology.

Ablation of phospholamban and sarcolipin results in cardiac hypertrophy and decreased cardiac contractility.

M. Nowycky, Lai-Hua Xie, C. Hong, 2011, Cardiovascular research.

Sarcoplasmic Reticulum Ca 2 1 ATPase ( SERCA ) 1 a Structurally Substitutes for SERCA 2 a in the Cardiac Sarcoplasmic Reticulum and Increases Cardiac Ca 2 1 Handling Capacity

E. Marbán, R. Walsh, V. Prasad, 2001 .

Handling Capacity

Mark A Sussman, E. Marbán, R. Walsh, 2001 .

Cardiac isoform of α-2 macroglobin, a novel serum protein, may induce cardiac hypertrophy in rats

F. Lottspeich, G. Babu, B. Kadenbach, 2001, Basic Research in Cardiology.

Sarcolipin overexpression impairs myogenic differentiation in Duchenne muscular dystrophy.

Lai-Hua Xie, D. Duan, N. Niranjan, 2019, American journal of physiology. Cell physiology.

Expression of SERCA isoform with faster Ca2+ transport properties improves postischemic cardiac function and Ca2+ handling and decreases myocardial infarction.

J. Zweier, M. Periasamy, Poornima Bhupathy, 2007, American journal of physiology. Heart and circulatory physiology.

Angiotensin II induces afterdepolarizations via reactive oxygen species and calmodulin kinase II signaling.

Lai-Hua Xie, G. Babu, N. Fefelova, 2011, Journal of molecular and cellular cardiology.

Increased Sarcolipin Expression and Adrenergic Drive in Humans With Preserved Left Ventricular Ejection Fraction and Chronic Isolated Mitral Regurgitation

T. Denney, L. Dell’Italia, H. Gupta, 2014, Circulation. Heart failure.

Mitochondria in Cardiovascular Physiology and Disease Xanthine oxidase inhibition preserves left ventricular systolic but not diastolic function in cardiac volume overload

S. Ballinger, L. Dell’Italia, V. Darley-Usmar, 2013 .

Ablation of smooth muscle myosin heavy chain SM2 increases smooth muscle contraction and results in postnatal death in mice

M. Periasamy, G. Babu, Yingbi Zhou, 2008, Proceedings of the National Academy of Sciences.

Increased sarcolipin expression and decreased sarco(endo)plasmic reticulum Ca2+ uptake in skeletal muscles of mouse models of Duchenne muscular dystrophy

J. Schneider, D. Fraidenraich, G. Babu, 2013, Journal of Muscle Research and Cell Motility.

Sarcolipin haploinsufficiency prevents dystrophic cardiomyopathy in mdx mice.

Lai-Hua Xie, N. Niranjan, G. Babu, 2020, American journal of physiology. Heart and circulatory physiology.

Cardiac Specific Expression of Threonine 5 to Alanine Mutant Sarcolipin Results in Structural Remodeling and Diastolic Dysfunction

G. Yehia, Lai-Hua Xie, G. Babu, 2015, PloS one.

Isoform switching from SM-B to SM-A myosin results in decreased contractility and altered expression of thin filament regulatory proteins.

R. Paul, M. Periasamy, G. Babu, 2004, American journal of physiology. Cell physiology.

The Smooth Muscle Myosin Seven Amino Acid Heavy Chain Insert's Kinetic Role in the Crossbridge Cycle for Mouse Bladder

M. Periasamy, G. Babu, F. Brozovich, 2003, The Journal of physiology.

Abnormal Calcium Handling in Duchenne Muscular Dystrophy: Mechanisms and Potential Therapies

D. Duan, G. Babu, Satvik Mareedu, 2021, Frontiers in Physiology.

The expression of SR calcium transport ATPase and the Na(+)/Ca(2+)Exchanger are antithetically regulated during mouse cardiac development and in Hypo/hyperthyroidism.

F. Wuytack, M. Periasamy, G. Babu, 2000, Journal of molecular and cellular cardiology.

Reducing sarcolipin expression improves muscle metabolism in mdx mice.

G. Babu, Satvik Mareedu, Rekha Balakrishnan, 2022, American journal of physiology. Cell physiology.

Single SERCA2a Therapy Ameliorated Dilated Cardiomyopathy for 18 Months in a Mouse Model of Duchenne Muscular Dystrophy.

R. Hajjar, D. Duan, N. Wasala, 2020, Molecular therapy : the journal of the American Society of Gene Therapy.

Reducing sarcolipin expression mitigates Duchenne muscular dystrophy and associated cardiomyopathy in mice

J. McArdle, J. Mendell, Lai-Hua Xie, 2017, Nature Communications.

Increased sarcolipin expression and decreased sarco(endo)plasmic reticulum Ca2+ uptake in skeletal muscles of mouse models of Duchenne muscular dystrophy

D. Fraidenraich, G. Babu, M. Shanmugam, 2013, Journal of Muscle Research and Cell Motility.

Differential expression of sarcolipin protein during muscle development and cardiac pathophysiology.

G. Billman, C. Carnes, M. Periasamy, 2007, Journal of molecular and cellular cardiology.

Sarcolipin and phospholamban as regulators of cardiac sarcoplasmic reticulum Ca2+ ATPase.

M. Periasamy, Poornima Bhupathy, G. Babu, 2007, Journal of molecular and cellular cardiology.

Smooth muscle myosin heavy chain isoforms and their role in muscle physiology

D. Warshaw, M. Periasamy, G. Babu, 2000, Microscopy research and technique.

Ablation of sarcolipin results in atrial remodeling.

Lai-Hua Xie, M. Periasamy, Ji Yeon Park, 2012, American journal of physiology. Cell physiology.

Loss of SM-B myosin affects muscle shortening velocity and maximal force development

S. Huke, R. Paul, M. Periasamy, 2001, Nature Cell Biology.

Solubilization of membrane proteins for two-dimensional gel electrophoresis: identification of sarcoplasmic reticulum membrane proteins.

M. Periasamy, G. Babu, O. Alzate, 2004, Analytical biochemistry.

Altered Active Zones, Vesicle Pools, Nerve Terminal Conductivity, and Morphology during Experimental MuSK Myasthenia Gravis

J. McArdle, B. Wilson, G. Babu, 2014, PloS one.

skeletal muscle from sarcolipin-null mice transport and muscle relaxation in

A. Gramolini, Subash C. Gupta, M. Trivieri, 2016 .

Enhanced Ca2+ transport and muscle relaxation in skeletal muscle from sarcolipin-null mice.

A. Gramolini, Subash C. Gupta, M. Trivieri, 2011, American journal of physiology. Cell physiology.

Threonine-5 at the N-terminus can modulate sarcolipin function in cardiac myocytes.

M. Periasamy, Poornima Bhupathy, G. Babu, 2009, Journal of molecular and cellular cardiology.

Effect of cardiac resynchronization therapy on myocardial gene expression in patients with nonischemic dilated cardiomyopathy.

S. Iyengar, W. Abraham, A. Ferketich, 2007, Journal of cardiac failure.

Targeted Overexpression of Sarcolipin in the Mouse Heart Decreases Sarcoplasmic Reticulum Calcium Transport and Cardiac Contractility*

G. Jagatheesan, M. Periasamy, Poornima Bhupathy, 2006, Journal of Biological Chemistry.

Transgenic mouse models for cardiac dysfunction by a specific gene manipulation.

M. Periasamy, G. Babu, 2005, Methods in molecular medicine.

Cardiac isoform of alpha-2 macroglobin, a novel serum protein, may induce cardiac hypertrophy in rats.

F. Lottspeich, G. Babu, B. Kadenbach, 2001, Basic Research in Cardiology.

Effects of h1‐calponin ablation on the contractile properties of bladder versus vascular smooth muscle in mice lacking SM‐B myosin

H. Yamamura, M. Periasamy, G. Babu, 2006, The Journal of physiology.

Overexpression of adenylyl cyclase type 5 (AC5) confers a proarrhythmic substrate to the heart.

S. Vatner, Lai-Hua Xie, D. Vatner, 2015, American journal of physiology. Heart and circulatory physiology.

Constriction velocities of renal afferent and efferent arterioles of mice are not related to SMB expression.

A. Patzak, M. Periasamy, G. Babu, 2005, Kidney international.

Time course of airway mechanics of the (+)insert myosin isoform knockout mouse.

J. Bates, M. Periasamy, G. Babu, 2004, American journal of respiratory cell and molecular biology.

SMB myosin heavy chain knockout enhances tonic contraction and reduces the rate of force generation in ileum and stomach antrum.

M. Periasamy, G. Babu, T. Eddinger, 2013, American journal of physiology. Cell physiology.

Adenylyl cyclase type 5 protein expression during cardiac development and stress.

S. Vatner, K. Iwatsubo, Y. Ishikawa, 2009, American journal of physiology. Heart and circulatory physiology.

Abstract 17445: Overexpression of Adenylyl Cyclase Type 5 (AC5) in the Heart Predisposes to Cardiac Arrhythmias

S. Vatner, K. Iwatsubo, Y. Ishikawa, 2010 .