Deyong Ye

发表

Discovery of styrylaniline derivatives as novel alpha-synuclein aggregates ligands.

Jiang Bian, Yi-Qi Liu, Jie He, 2021, European journal of medicinal chemistry.

Discovery of flavonoid derivatives as anti-HCV agents via pharmacophore search combining molecular docking strategy.

Wei Li, Jian-Ping Zuo, Deyong Ye, 2012, European journal of medicinal chemistry.

An allosteric PGAM1 inhibitor effectively suppresses pancreatic ductal adenocarcinoma

Saijuan Chen, Minmin Shi, Jing Chen, 2019, Proceedings of the National Academy of Sciences.

Discovery of Novel 3-Hydroxyquinazoline-2,4(1H,3H)-Dione Derivatives: A Series of Metal Ion Chelators with Potent Anti-HCV Activities

Deyong Ye, Yang Cao, Lu Zhou, 2022, International journal of molecular sciences.

HIGHLY DIASTEREOSELECTIVE EPOXIDATION OF CYCLOALKENOLS WITH MONOPEROXYPHTHALIC ACID IN WATER

O. Piermatti, Deyong Ye, F. Fringuelli, 1997 .

The discovery of novel benzothiazinones as highly selective non-ATP competitive glycogen synthase kinase 3β inhibitors for the treatment of ovarian cancer.

Deyong Ye, Yong Chu, Weicheng Zhou, 2017, European journal of medicinal chemistry.

Site-selective phosphoglycerate mutase 1 acetylation by a small molecule.

M. Uesugi, Chao Peng, Deyong Ye, 2020, ACS chemical biology.

Discovery of Novel Benzothiazepinones as Irreversible Covalent Glycogen Synthase Kinase 3β Inhibitors for the Treatment of Acute Promyelocytic Leukemia.

J. Bian, Chao Peng, Jie He, 2021, Journal of medicinal chemistry.

2-Hydroxy-oleic acid does not activate sphingomyelin synthase activity

Jibin Dong, Ting-bo Ding, Deyong Ye, 2018, The Journal of Biological Chemistry.

Analysis of Fluorescent Ceramide and Sphingomyelin Analogs: A Novel Approach for in Vivo Monitoring of Sphingomyelin Synthase Activity

Shuang Hu, Deyong Ye, Ping Chen, 2014, Lipids.

Sphingomyelin synthase 2 is a positive regulator of the CSF1R-STAT3 pathway in pancreatic cancer-associated macrophage

Jibin Dong, Ting-bo Ding, Deyong Ye, 2022, Frontiers in Pharmacology.

The domain responsible for sphingomyelin synthase (SMS) activity.

Renxiao Wang, Deyong Ye, Xian-cheng Jiang, 2008, Biochimica et biophysica acta.

Novel benzothiazinones (BTOs) as allosteric modulator or substrate competitive inhibitor of glycogen synthase kinase 3β (GSK-3β) with cellular activity of promoting glucose uptake.

Deyong Ye, Yong Chu, Peng Zhang, 2014, Bioorganic & medicinal chemistry letters.

Identification of novel scaffold of benzothiazepinones as non-ATP competitive glycogen synthase kinase-3β inhibitors through virtual screening.

P. Zhang, Deyong Ye, Yong Chu, 2012, Bioorganic & medicinal chemistry letters.

Increasing the Level of IRS-1 and Insulin Pathway Sensitivity by Natural Product Carainterol A

Yao Gao, X. Qin, Li Gao, 2016, Molecules.

Discovery, synthesis and biological evaluation of 2-(4-(N-phenethylsulfamoyl)phenoxy)acetamides (SAPAs) as novel sphingomyelin synthase 1 inhibitors.

Ya-li Li, Ting-bo Ding, Xiaodong Deng, 2015, Bioorganic & medicinal chemistry.

Discovery of the selective sphingomyelin synthase 2 inhibitors with the novel structure of oxazolopyridine.

Ya-li Li, Deyong Ye, Ming-guang Mo, 2017, Bioorganic & medicinal chemistry letters.

Development, Validation, and Application of a Novel Method for Mammalian Sphingomyelin Synthase Activity Measurement

Xiaodong Deng, Deyong Ye, Yong Chu, 2012 .

Design, synthesis and biological evaluation of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3β (GSK-3β).

P. Zhang, Deyong Ye, Yong Chu, 2013, European journal of medicinal chemistry.

An efficient one-pot procedure for the synthesis of 1,5-benzothiazepinones catalyzed by tetrabutylammonium fluoride (TBAF)

Deyong Ye, Yong Chu, Peng Zhang, 2016 .

Discovery and anti-inflammatory evaluation of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3β (GSK-3β).

Deyong Ye, Yong Chu, Peng Zhang, 2018, Bioorganic & medicinal chemistry.

Design, Synthesis and Biological Evaluation of Benzothiazepinones (BTZs) as Novel Non‐ATP Competitive Inhibitors of Glycogen Synthase Kinase‐3β (GSK‐3β).

Deyong Ye, Yong Chu, Peng Zhang, 2013 .

Identification of small molecule sphingomyelin synthase inhibitors.

Renxiao Wang, Ting-bo Ding, Xiaodong Deng, 2014, European journal of medicinal chemistry.

Discovery of 4-Benzyloxybenzo[ d]isoxazole-3-amine Derivatives as Highly Selective and Orally Efficacious Human Sphingomyelin Synthase 2 Inhibitors that Reduce Chronic Inflammation in db/ db Mice.

Deyong Ye, Yong Chu, Xian-cheng Jiang, 2018, Journal of medicinal chemistry.

Discovery, synthesis and anti-atherosclerotic activities of a novel selective sphingomyelin synthase 2 inhibitor.

Ting-bo Ding, Deyong Ye, Yong Chu, 2019, European journal of medicinal chemistry.

Efficient and scalable process for the synthesis of antihypercholesterolemic drug ezetimibe

Deyong Ye, Weicheng Zhou, Shunli Zhang, 2016 .

(E)-3-(8-Benzyloxy-2,3-dihydro-1,4-benzodioxin-6-yl)-1-[2-hydroxy-4,6-bis(methoxymethoxy)phenyl]prop-2-en-1-one

Yu Zhang, Y. Zhang, Deyong Ye, 2011, Acta crystallographica. Section E, Structure reports online.

Design and Synthesis of the Diazirine-based Clickable Photo-affinity Probe Targeting Sphingomyelin Synthase 2

Deyong Ye, Zhining Li, Lulu Jiang, 2019, Letters in Drug Design & Discovery.

Pharmacologic Inhibition of Sphingomyelin Synthase (SMS) Activity Reduces Apolipoprotein-B Secretion from Hepatocytes and Attenuates Endotoxin-Mediated Macrophage Inflammation

Ting-bo Ding, Xiaodong Deng, Deyong Ye, 2014, PloS one.

Molecular Modeling of the Three-Dimensional Structure of Human Sphingomyelin Synthase

Renxiao Wang, Xiaodong Deng, Deyong Ye, 2011 .

Efficient preparation of (R)-2-(2,5-difluorophenyl)pyrrolidine via a recycle process of resolution.

Deyong Ye, Weicheng Zhou, Kuaile Lin, 2021, Chirality.

Synthesis and biological evaluation of anthraquinone derivatives as allosteric phosphoglycerate mutase 1 inhibitors for cancer treatment.

C. Shan, Deyong Ye, Lulu Jiang, 2019, European journal of medicinal chemistry.

Antitumor agents 294. Novel E-ring-modified camptothecin-4β-anilino-4'-O-demethyl-epipodophyllotoxin conjugates as DNA topoisomerase I inhibitors and cytotoxic agents.

C. Leung, Shin-Young Park, Hao Zhu, 2012, Bioorganic & medicinal chemistry.

Rational design of 2-pyrrolinones as inhibitors of HIV-1 integrase.

Deyong Ye, Yong Chu, W. Fu, 2011, Bioorganic & medicinal chemistry letters.

First total synthesis of (+)-Carainterol A

Deyong Ye, Yong Chu, Mingming Liu, 2010 .

Sphingomyelin synthase 2 facilitates M2-like macrophage polarization and tumor progression in a mouse model of triple-negative breast cancer

Ting-bo Ding, Deyong Ye, Xian-cheng Jiang, 2020, Acta Pharmacologica Sinica.

Tetrazole and triazole as bioisosteres of carboxylic acid: discovery of diketo tetrazoles and diketo triazoles as anti-HCV agents.

Lu Zhou, Deyong Ye, Wu Song, 2013, Bioorganic & medicinal chemistry letters.

A novel and practical asymmetric synthesis of dapoxetine hydrochloride

Deyong Ye, Hongyan Li, Weicheng Zhou, 2015, Beilstein journal of organic chemistry.

Sphingomyelin synthase 2 facilitates M2-like macrophage polarization and tumor progression in a mouse model of triple-negative breast cancer

K. Yu, Ting-bo Ding, Deyong Ye, 2020, Acta Pharmacologica Sinica.

A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer.

W. Lu, Ying Shen, Hong-Zhuan Chen, 2019, Cell metabolism.

Discovery of Metal Ions Chelator Quercetin Derivatives with Potent Anti-HCV Activities

Deyong Ye, Yang Cao, Mingming Liu, 2015, Molecules.

2-(Furan-2-yl)-5-(2-nitrobenzyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one

Deyong Ye, Yong Chu, Zhaohua Huang, 2010, Acta crystallographica. Section E, Structure reports online.

Xanthone derivatives as phosphoglycerate mutase 1 inhibitors: Design, synthesis, and biological evaluation.

Deyong Ye, Shiyu Zhang, Yang Cao, 2018, Bioorganic & medicinal chemistry.

Design, Synthesis, and Biological Evaluation of Novel Dual Inhibitors of Secretory Phospholipase A2 and Sphingomyelin Synthase

Deyong Ye, Xing Gao, Lu Zhou, 2013 .

Tumor cell membrane-targeting pH-dependent electron donor-acceptor fluorescence systems with low background signals.

Ning Zhang, Deyong Ye, Liang Han, 2014, Biomaterials.

Choline‐Derivate‐Modified Nanoparticles for Brain‐Targeting Gene Delivery

Rongqin Huang, Deyong Ye, Liang Han, 2011, Advanced materials.

Design, synthesis and identification of N, N-dibenzylcinnamamide (DBC) derivatives as novel ligands for α-synuclein fibrils by SPR evaluation system.

J. Bian, Xin Lin, Wen-Bo Yu, 2020, Bioorganic & medicinal chemistry.

The Design and Synthesis of N-Xanthone Benzenesulfonamides as Novel Phosphoglycerate Mutase 1 (PGAM1) Inhibitors

Deyong Ye, Yang Cao, Lu Zhou, 2018, Molecules.

Development of Anthraquinone Analogues as Phosphoglycerate Mutase 1 Inhibitors

Deyong Ye, Lu Zhou, Ke Huang, 2019, Molecules.

A selective sphingomyelin synthase 2 inhibitor ameliorates diet induced insulin resistance via the IRS-1/Akt/GSK-3β signaling pathway.

Yutong Huang, Deyong Ye, Yali Li, 2019, Die Pharmazie.

Discovery of a highly potent CECR2 bromodomain inhibitor with 7H-pyrrolo[2,3-d] pyrimidine scaffold.

Kaixian Chen, Hualiang Jiang, Bo Li, 2022, Bioorganic chemistry.

Assignment of NMR data and Conformational analysis of larotrectinib and its precursors

Deyong Ye, Yan Zheng, Kuaile Lin, 2021 .

A novel Friedel–Crafts alkylation of naphthols without Lewis acid

Deyong Ye, Kuaile Lin, Yijun Zhu, 2015 .