H. Hong

发表

Congo red and thioflavin-T analogs detect Abeta oligomers.

K. Lam, H. Kung, F. LaFerla, 2008, Journal of Neurochemistry.

Discovery of an Orally Bioavailable Benzofuran Analogue That Serves as a β-Amyloid Aggregation Inhibitor for the Potential Treatment of Alzheimer's Disease.

Jiyoun Lee, D. Jo, H. Hong, 2018, Journal of medicinal chemistry.

3D Light-Sheet Fluorescence Microscopy of Cranial Neurons and Vasculature during Zebrafish Embryogenesis

Young Ho Kim, B. J. Hwang, Ok Kyu Park, 2015, Molecules and cells.

ERK1/2 is an endogenous negative regulator of the γsecretase activity

I. Mook‐Jung, E. Baik, H. Hong, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Two β-strands of RAGE participate in the recognition and transport of amyloid-β peptide across the blood brain barrier.

C. Choi, H. Hong, Sangho Lee, 2013, Biochemical and biophysical research communications.

Lovastatin enhances Aβ production and senile plaque deposition in female Tg2576 mice

J. H. Boo, I. Mook‐Jung, Seung U. Kim, 2003, Neurobiology of Aging.

Amyloid peptide attenuates the proteasome activity in neuronal cells

I. Mook‐Jung, H. Hong, Sangsoo Oh, 2005, Mechanisms of Ageing and Development.

PiB-PET Imaging-Based Serum Proteome Profiles Predict Mild Cognitive Impairment and Alzheimer's Disease.

D. Hwang, D. Na, S. Seo, 2016, Journal of Alzheimer's disease : JAD.

Interferon gamma stimulates beta-secretase expression and sAPPbeta production in astrocytes.

J. H. Boo, I. Mook‐Jung, S. U. Kim, 2003, Biochemical and biophysical research communications.

Upregulation of amyloid precursor protein by platelet-derived growth factor in hippocampal precursor cells

I. Mook‐Jung, H. Hong, Y. Kwon, 2007, Neuroreport.

RAGE regulates BACE1 and Aβ generation via NFAT1 activation in Alzheimer's disease animal model

I. Mook‐Jung, S. Kim, S. Son, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

6-Phenoxy-2-phenylbenzoxazoles, novel inhibitors of receptor for advanced glycation end products (RAGE).

Jiyoun Lee, Y. Suh, H. Hong, 2015, Bioorganic & medicinal chemistry.

Aβ1–42-RAGE Interaction Disrupts Tight Junctions of the Blood–Brain Barrier Via Ca2+-Calcineurin Signaling

C. Ha, I. Mook‐Jung, H. Hong, 2012, The Journal of Neuroscience.

Mitochondria-Specific Accumulation of Amyloid β Induces Mitochondrial Dysfunction Leading to Apoptotic Cell Death

I. Mook‐Jung, Sun-ho Han, S. Son, 2012, PloS one.

The Influence of Spin-Labeled Fluorene Compounds on the Assembly and Toxicity of the Aβ Peptide

T. Kálai, K. Hideg, A. Parikh, 2012, PloS one.

Candidate anti-Aβ fluorene compounds selected from analogs of amyloid imaging agents

K. Lam, R. Cheng, R. Vassar, 2010, Neurobiology of Aging.

Constitutive JAK2/STAT1 activation regulates endogenous BACE1 expression in neurons.

I. Mook‐Jung, S. Son, Yong Woo Kim, 2009, Biochemical and biophysical research communications.

Ligand-based design, synthesis, and biological evaluation of 2-aminopyrimidines, a novel series of receptor for advanced glycation end products (RAGE) inhibitors.

Hyun-Ju Park, Y. Suh, H. Hong, 2012, Journal of medicinal chemistry.

Tomoregulin (TMEFF2) Binds Alzheimer's Disease Amyloid-β (Aβ) Oligomer and AβPP and Protects Neurons from Aβ-Induced Toxicity.

Izumi Maezawa, H. Hong, J. Petrlova, 2015, Journal of Alzheimer's disease : JAD.

Synthesis and Evaluation of a Novel Deguelin Derivative, L80, which Disrupts ATP Binding to the C-terminal Domain of Heat Shock Protein 90

So-Jung Park, Hyun-Ju Park, Ho-Yyoung Lee, 2015, Molecular Pharmacology.

Mitochondrial ATP synthase activity is impaired by suppressed O-GlcNAcylation in Alzheimer's disease.

M. Murray, D. Dickson, E. Yi, 2015, Human molecular genetics.

Mapping the structural transition in an amyloidogenic apolipoprotein A-I.

J. Voss, L. Roberts, P. Fitzgerald, 2007, Biochemistry.

Effect of Ischemic Neuronal Insults on Amyloid Precursor Protein Processing

J. H. Boo, I. Mook‐Jung, H. Hong, 2006, Neurochemical Research.

Intracellular amyloid-β accumulation in calcium-binding protein-deficient neurons leads to amyloid-β plaque formation in animal model of Alzheimer's disease.

Sung Hoon Baik, Hyundong Song, I. Mook‐Jung, 2012, Journal of Alzheimer's disease : JAD.

FK506 reduces amyloid plaque burden and induces MMP-9 in AβPP/PS1 double transgenic mice.

S. Son, H. Hong, M. Moon, 2010, Journal of Alzheimer's disease : JAD.

The novel RAGE interactor PRAK is associated with autophagy signaling in Alzheimer’s disease pathogenesis

Hyundong Song, I. Mook‐Jung, S. Son, 2016, Molecular Neurodegeneration.

O-linked β-N-acetylglucosaminidase inhibitor attenuates β-amyloid plaque and rescues memory impairment

J. H. Boo, J. Cho, Hyundong Song, 2013, Neurobiology of Aging.

Discovery of Potent Human Glutaminyl Cyclase Inhibitors as Anti-Alzheimer's Agents Based on Rational Design.

M. Cui, Sun Choi, Jiyoun Lee, 2017, Journal of medicinal chemistry.

The novel RAGE interactor PRAK is associated with autophagy signaling in Alzheimer’s disease pathogenesis

Hyundong Song, I. Mook‐Jung, Sun-ho Han, 2016, Molecular Neurodegeneration.

Neuroprotective effect of genistein against beta amyloid-induced neurotoxicity

J. H. Boo, I. Mook‐Jung, Dong Hyun Kim, 2004, Neurobiology of Disease.

Ghrelin ameliorates cognitive dysfunction and neurodegeneration in intrahippocampal amyloid-β1-42 oligomer-injected mice.

M. Oh, I. Mook‐Jung, H. Hong, 2011, Journal of Alzheimer's disease : JAD.

Impaired Short-Term Plasticity in Mossy Fiber Synapses Caused by Mitochondrial Dysfunction of Dentate Granule Cells Is the Earliest Synaptic Deficit in a Mouse Model of Alzheimer's Disease

Suk-Ho Lee, I. Mook‐Jung, S. H. Lee, 2012, The Journal of Neuroscience.

Congo red and thioflavin‐T analogs detect Aβ oligomers

H. Kung, F. LaFerla, M. Kung, 2007 .

A novel tricyclic pyrone compound ameliorates cell death associated with intracellular amyloid‐β oligomeric complexes

Takeo Iwamoto, T. Iwamoto, Srinivas K. Battina, 2006, Journal of neurochemistry.

Ginsenoside Rb1 and Rg1 improve spatial learning and increase hippocampal synaptophysin level in mice

J. H. Boo, I. Mook‐Jung, M. Y. Cheong, 2001, Journal of neuroscience research.

Single-cell mechanics provides a sensitive and quantitative means for probing amyloid-β peptide and neuronal cell interactions

V. Lulevich, Gang-yu Liu, H. Hong, 2010, Proceedings of the National Academy of Sciences.

A differential association of Apolipoprotein E isoforms with the amyloid‐β oligomer in solution

J. Voss, G. Lorigan, H. Hong, 2011, Proteins.

Contribution of presenilin/γ-secretase to calsenilin-mediated apoptosis

D. Jo, I. Mook‐Jung, Jae-Woong Chang, 2003 .

Identification of disulfide cross-linked tau dimer responsible for tau propagation

Dong Jin Kim, H. Rhim, Young‐Tae Chang, 2015, Scientific Reports.

Neuroprotective effects of estrogen against beta-amyloid toxicity are mediated by estrogen receptors in cultured neuronal cells

I. Mook‐Jung, Seung U. Kim, H. Hong, 2001, Neuroscience Letters.

Inhibition of Alzheimer’s amyloid toxicity with a tricyclic pyrone molecule in vitro and in vivo

Aibin Shi, Sandeep Rana, D. Hua, 2009, Journal of neurochemistry.

Combining the rapid MTT formazan exocytosis assay and the MC65 protection assay led to the discovery of carbazole analogs as small molecule inhibitors of Aβ oligomer-induced cytotoxicity

K. Lam, R. Diaz-Avalos, R. Cheng, 2007, Brain Research.

Human serum transthyretin levels correlate inversely with Alzheimer's disease.

D. Na, Namjung Huh, Manho Kim, 2011, Journal of Alzheimer's disease : JAD.

Aβ1–42-RAGE Interaction Disrupts Tight Junctions of the Blood–Brain Barrier Via Ca2+-Calcineurin Signaling

C. Ha, H. Hong, Sunghoe Chang, 2012, The Journal of Neuroscience.

Syntheses of tricyclic pyrones and pyridinones and protection of Abeta-peptide induced MC65 neuronal cell death.

Sandeep Rana, D. Hua, H. Hong, 2009, Bioorganic & medicinal chemistry letters.

PiB-PET Imaging-Based Serum Proteome Profiles Predict Mild Cognitive Impairment and Alzheimer's Disease.

D. Hwang, D. Na, S. Seo, 2016, Journal of Alzheimer's disease : JAD.

Tomoregulin (TMEFF2) Binds Alzheimer's Disease Amyloid-β (Aβ) Oligomer and AβPP and Protects Neurons from Aβ-Induced Toxicity.

Izumi Maezawa, H. Hong, J. Petrlova, 2015, Journal of Alzheimer's disease : JAD.