C. Cairo

发表

Analysis of molecular diffusion by first-passage time variance identifies the size of confinement zones.

D. Golan, G. de Vries, G. Carrero, 2011, Biophysical journal.

Immobilization of carbohydrate epitopes for surface plasmon resonance using the Staudinger ligation.

C. Cairo, Ravi S. Loka, 2010, Carbohydrate research.

PROMOTING RECEPTOR CLUSTERING WITH MULTIVALENT LIGANDS AND IDENTIFYING LIGANDS FOR THE BETA-AMYLOID PEPTIDE

C. Cairo, 2002 .

Detection of Diffusion Heterogeneity in Single Particle Tracking Trajectories Using a Hidden Markov Model with Measurement Noise Propagation

Christopher W. Cairo, Nigel J. Burroughs, Paddy J. Slator, 2015, PloS one.

Selective immobilization of multivalent ligands for surface plasmon resonance and fluorescence microscopy.

R. M. Owen, L. Kiessling, J. Gestwicki, 2002, Analytical biochemistry.

Characterization of ABH‐subtype donor‐specific antibodies in ABO‐A‐incompatible kidney transplantation

T. Lowary, C. Cairo, L. West, 2021, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Screening Glycolipids Against Proteins in Vitro Using Picodiscs and Catch-and-Release Electrospray Ionization-Mass Spectrometry.

G. Privé, K. Ng, J. Klassen, 2016, Analytical chemistry.

Protein-glycosphingolipid interactions revealed using catch-and-release mass spectrometry.

J. Klassen, C. Cairo, Yixuan Zhang, 2012, Analytical chemistry.

Picodiscs for facile protein-glycolipid interaction analysis.

G. Privé, J. Klassen, C. Cairo, 2015, Analytical chemistry.

Crystal structures of human lysosomal EPDR1 reveal homology with the superfamily of bacterial lipoprotein transporters.

G. Privé, J. Klassen, C. Cairo, 2019 .

Crystal structures of human lysosomal EPDR1 reveal homology with the superfamily of bacterial lipoprotein transporters

G. Privé, J. Klassen, C. Cairo, 2019, Communications Biology.

Construction of Multivalent Homo- and Heterofunctional ABO Blood Group Glycoconjugates Using a Trifunctional Linker Strategy.

T. Lowary, C. Cairo, L. West, 2018, Bioconjugate chemistry.

Galectin-3 alters the lateral mobility and clustering of β1-integrin receptors

C. Cairo, M. Eckermann, Md. Amran Howlader, 2017, PloS one.

NIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies: Comparison of Results from Diverse Analytical Methods*

Erdmann Rapp, David J. Harvey, Stephen E. Stein, 2019, Molecular & Cellular Proteomics.

Limited Hydrolysis of Polysialic Acid by Human Neuraminidase Enzymes

C. Cairo, Carmanah D. Hunter, 2021 .

A FRET probe for cell-based imaging of ganglioside-processing enzyme activity and high-throughput screening.

S. Withers, Guangyu Yang, Yan Feng, 2015, Angewandte Chemie.

Glycoform remodeling generates a synthetic T cell phenotype.

C. Cairo, Ravi S. Loka, Chunxia Zou, 2013, Bioconjugate chemistry.

Persistent reduction in sialylation of cerebral glycoproteins following postnatal inflammatory exposure

Wyston C Pierre, A. Pshezhetsky, G. Lodygensky, 2018, Journal of Neuroinflammation.

Identification of fluorogenic and quenched benzoxadiazole reactive chromophores

C. Cairo, Jessie A. Key, 2011 .

A tyrosine sulfation–dependent HLA-I modification identifies memory B cells and plasma cells

M. Moran, A. Bar-Or, J. Wither, 2018, Science Advances.

Inhibitors of the human neuraminidase enzymes

C. Cairo, 2014 .

Neuraminidases 1 and 3 Trigger Atherosclerosis by Desialylating Low‐Density Lipoproteins and Increasing Their Uptake by Macrophages

A. Orekhov, A. Pshezhetsky, R. Roy, 2021, Journal of the American Heart Association.

Practical Labeling Methodology for Choline‐Derived Lipids and Applications in Live Cell Fluorescence Imaging

C. Cairo, Feng Jia, Caishun Li, 2014, Photochemistry and photobiology.

Conjugation of A and B Blood Group Structures to Silica Microparticles for the Detection of Antigen-Specific B Cells.

J. Buriak, T. Lowary, I. E. Dijke, 2016, Bioconjugate chemistry.

The Janus‐like role of neuraminidase isoenzymes in inflammation

A. Pshezhetsky, C. Cairo, Md. Amran Howlader, 2021, bioRxiv.

Therapeutic Effect of Neuraminidase-1–Selective Inhibition in Mouse Models of Bleomycin-Induced Pulmonary Inflammation and Fibrosis

E. Lillehoj, S. Goldblum, H. Ishida, 2020, The Journal of Pharmacology and Experimental Therapeutics.

Substrate recognition of the membrane-associated sialidase NEU3 requires a hydrophobic aglycone.

D. Bundle, J. Klassen, C. Cairo, 2011, Biochemistry.

Inhibitor selectivity of a new class of oseltamivir analogs against viral neuraminidase over human neuraminidase enzymes.

B. M. Pinto, S. Mohan, C. Cairo, 2011, Bioorganic & medicinal chemistry.

Human neuraminidases have reduced activity towards modified sialic acids on glycoproteins.

C. Cairo, Carmanah D. Hunter, Elizabeth M Porter, 2020, Carbohydrate research.

Extending the in vivo persistence of synthetic glycoconjugates using a serum-protein binder

C. Cairo, L. West, B. Motyka, 2022, RSC chemical biology.

Profiling of glycosphingolipids with SCDase digestion and HPLC-FLD-MS.

C. Cairo, Béla Reiz, Radhika Chakraberty, 2021, Analytical biochemistry.

Conjugation of synthetic N-acetyl-lactosamine to azide-containing proteins using the Staudinger ligation.

C. Cairo, Ravi S. Loka, C. Sadek, 2010, Bioconjugate chemistry.

Selective Inhibitors of Human Neuraminidase 3.

A. Pshezhetsky, B. Ernst, A. Fougerat, 2018, Journal of medicinal chemistry.

Human Neuraminidase Isoenzymes Show Variable Activities for 9- O-Acetyl-sialoside Substrates.

M. R. Richards, J. Klassen, C. Cairo, 2018, ACS chemical biology.

Mycobacterial Phenolic Glycolipids with a Simplified Lipid Aglycone Modulate Cytokine Levels through Toll‐Like Receptor 2

T. Lowary, C. Cairo, D. Barreda, 2013, Chembiochem : a European journal of chemical biology.

New Answers to Old Conundrums: What Antibodies, Exosomes and Inflammasomes Bring to the Conversation. Canadian National Transplant Research Program International Summit Report

T. Mohanakumar, R. Fairchild, C. Cairo, 2017, Transplantation.

A Hidden Markov Model for Single Particle Tracks Quantifies Dynamic Interactions between LFA-1 and the Actin Cytoskeleton

Raibatak Das, Christopher W. Cairo, Daniel Coombs, 2009, PLoS Comput. Biol..

Synthesis of α-brominated phosphonates and their application as phosphate bioisosteres

C. Cairo, A. Downey, 2014 .

Synthetic Strategies for Modified Glycosphingolipids and Their Design as Probes.

M. R. Richards, C. Cairo, Tianlin Guo, 2018, Chemical reviews.

Photophysical characterization of triazole-substituted coumarin fluorophores

Alex Brown, Q. K. Timerghazin, C. Cairo, 2009 .

α-Bromophosphonate analogs of glucose-6-phosphate are inhibitors of glucose-6-phosphatase.

C. Cairo, A. Downey, 2013, Carbohydrate research.

Influencing receptor-ligand binding mechanisms with multivalent ligand architecture.

Jason E Gestwicki, Laura L Kiessling, K. Oetjen, 2002, Journal of the American Chemical Society.

Detection of cellular sialic acid content using nitrobenzoxadiazole carbonyl-reactive chromophores.

C. Cairo, Caishun Li, Jessie A. Key, 2012, Bioconjugate chemistry.

NEU1 and NEU3 enzymes alter CD22 organization on B cells

C. Cairo, Caishun Li, Ha Tran, 2021, bioRxiv.

Cell aggregation by scaffolded receptor clusters.

Jason E Gestwicki, Laura L Kiessling, L. Kiessling, 2002, Chemistry & biology.

ABH‐Glycan Microarray Characterizes ABO Subtype Antibodies: Fine Specificity of Immune Tolerance After ABO‐Incompatible Transplantation

J. Buriak, M. Burch, D. Ross, 2016, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Protecting group-free immobilization of glycans for affinity chromatography using glycosylsulfonohydrazide donors.

M. R. Richards, C. Cairo, Daniel Hernandez Armada, 2015, Carbohydrate research.

Selective Inhibitors of Human Neuraminidase 1 (NEU1).

A. Pshezhetsky, C. Cairo, Tianlin Guo, 2018, Journal of medicinal chemistry.

Insight into substrate recognition and catalysis by the human neuraminidase 3 (NEU3) through molecular modeling and site-directed mutagenesis.

C. Cairo, R. Zheng, Amgad Albohy, 2010, Glycobiology.

Mapping substrate interactions of the human membrane-associated neuraminidase, NEU3, using STD NMR.

M. R. Richards, C. Cairo, Amgad Albohy, 2015, Glycobiology.

Control of multivalent interactions by binding epitope density.

Jason E Gestwicki, Laura L Kiessling, M. Kanai, 2002, Journal of the American Chemical Society.

Integrin-mediated cell migration is blocked by inhibitors of human neuraminidase.

C. Cairo, Feng Jia, Md. Amran Howlader, 2016, Biochimica et biophysica acta.

Selection of galectin‐3 ligands derived from genetically encoded glycopeptide libraries

R. Derda, P. Kitov, C. Cairo, 2018, Peptide Science.

Inhibitors of Human Neuraminidase Enzymes Block Transmigration in vitro

C. Cairo, Md. Amran Howlader, Tianlin Guo, 2022, Frontiers in Molecular Biosciences.

Interlaboratory Study on Differential Analysis of Protein Glycosylation by Mass Spectrometry: The ABRF Glycoprotein Research Multi-Institutional Study 2012*

Haixu Tang, Daniel Kolarich, Wolfgang Jabs, 2013, Molecular & Cellular Proteomics.

Sialidase NEU4 is involved in glioblastoma stem cell survival

M. Di Nicola, C. Cairo, R. Zappasodi, 2014, Cell Death and Disease.

Positive Regulation of Insulin Signaling by Neuraminidase 1

A. Pshezhetsky, P. Thibault, N. Heveker, 2013, Diabetes.

Enhanced Cross-Linking of Diazirine-Modified Sialylated Glycoproteins Enabled through Profiling of Sialidase Specificities.

Jennifer J. Kohler, C. Cairo, J. McCombs, 2016, ACS chemical biology.

Neuraminidase-3 Is a Negative Regulator of LFA-1 Adhesion

C. Cairo, Md. Amran Howlader, Chunxia Zou, 2019, Front. Chem..

Identification of selective inhibitors for human neuraminidase isoenzymes using C4,C7-modified 2-deoxy-2,3-didehydro-N-acetylneuraminic acid (DANA) analogues.

A. Pshezhetsky, C. Cairo, Amgad Albohy, 2013, Journal of medicinal chemistry.

Neuraminidase 1 activates insulin receptor and reverses insulin resistance in obese mice

A. Pshezhetsky, N. Heveker, J. Medin, 2018, Molecular metabolism.

Analysis of two-dimensional dissociation constant of laterally mobile cell adhesion molecules.

Michael Loran Dustin, D. Golan, C. Cairo, 2007, Biophysical journal.

Dynamic Regulation of CD45 Lateral Mobility by the Spectrin-Ankyrin Cytoskeleton of T Cells*

Raibatak Das, Christopher W. Cairo, Daniel Coombs, 2010, The Journal of Biological Chemistry.

Cytoskeletal regulation couples LFA-1 conformational changes to receptor lateral mobility and clustering.

D. Golan, C. Cairo, Christopher W Cairo, 2006, Immunity.

Fluorescent small-molecule probes of biochemistry at the plasma membrane.

C. Cairo, C. Sadek, Jessie A. Key, 2010, Current opinion in chemical biology.

Structural Basis for Substrate Specificity of Mammalian Neuraminidases

A. Pshezhetsky, E. Korchagina, N. Bovin, 2014, PloS one.

Visualization and characterization of receptor clusters by transmission electron microscopy.

L. Kiessling, J. Gestwicki, C. Cairo, 2003, Methods in enzymology.

Persistent reduction in sialylation of cerebral glycoproteins following postnatal inflammatory exposure

Wyston C Pierre, A. Pshezhetsky, G. Lodygensky, 2018, Journal of Neuroinflammation.

Conformational analysis of peramivir reveals critical differences between free and enzyme-bound states

M. R. Richards, C. Cairo, J. Wulff, 2014 .

Inhibition of human neuraminidase 3 (NEU3) by C9-triazole derivatives of 2,3-didehydro-N-acetyl-neuraminic acid.

C. Cairo, Mahendra Sandbhor, Amgad Albohy, 2010, Bioorganic & medicinal chemistry letters.

Identification of Selective Nanomolar Inhibitors of the Human Neuraminidase, NEU4.

A. Pshezhetsky, C. Cairo, Amgad Albohy, 2013, ACS medicinal chemistry letters.

A protected l-bromophosphonomethylphenylalanine amino acid derivative (BrPmp) for synthesis of irreversible protein tyrosine phosphatase inhibitors.

C. Cairo, A. Downey, A. M. Downey, 2010, Bioorganic & medicinal chemistry.

Isoenzyme-Selective Inhibitors of Human Neuraminidases Reveal Distinct Effects on Cell Migration.

C. Cairo, Md. Amran Howlader, Tianlin Guo, 2020, ACS chemical biology.

T cell adhesion mechanisms revealed by receptor lateral mobility.

D. Golan, C. Cairo, Christopher W Cairo, 2008, Biopolymers.

Examining the Role of Glycolipids in Integrin and B Cell Receptor Activation

C. Cairo, L. West, Caishun Li, 2013 .

A monomeric photoconvertible fluorescent protein for imaging of dynamic protein localization.

M. Davidson, R. Campbell, Nathan Christopher Shaner, 2010, Journal of molecular biology.

Molecular dynamics simulations of viral neuraminidase inhibitors with the human neuraminidase enzymes: Insights into isoenzyme selectivity.

M. R. Richards, C. Cairo, Tianlin Guo, 2018, Bioorganic & medicinal chemistry.

Affinity-Based Inhibition of β-Amyloid Toxicity†

Christopher W. Cairo, Regina M. Murphy, Andrea Strzelec, 2002 .

Affinity-based inhibition of beta-amyloid toxicity.

Regina M Murphy, Andrea Strzelec, Laura L Kiessling, 2002, Biochemistry.

Substituted benzoxadiazoles as fluorogenic probes: a computational study of absorption and fluorescence.

Alex Brown, C. Cairo, Tsz Yan Ngai, 2012, The journal of physical chemistry. A.

Crystal structures of human lysosomal EPDR1 reveal homology with the superfamily of bacterial lipoprotein transporters

G. Privé, J. Klassen, C. Cairo, 2019, Communications Biology.

Signaling by committee: receptor clusters determine pathways of cellular activation.

C. Cairo, 2007, ACS chemical biology.

Mechanisms of Cellular Avidity Regulation in CD2-CD58-Mediated T Cell Adhesion.

Michael Loran Dustin, D. Golan, C. Cairo, 2006, ACS chemical biology.

Designed potent multivalent chemoattractants for Escherichia coli.

A. M. Schnoes, L. Kiessling, J. Gestwicki, 2001, Bioorganic & medicinal chemistry.

A modular synthesis of alkynyl-phosphocholine headgroups for labeling sphingomyelin and phosphatidylcholine.

C. Cairo, Mahendra Sandbhor, I. S. Strelkov, 2009, The Journal of organic chemistry.

A quantitative, high-throughput method identifies protein–glycan interactions via mass spectrometry

Matthew S Macauley, P. Kitov, J. Klassen, 2019, Communications Biology.

Crystal structures of human lysosomal EPDR1 reveal homology with the superfamily of bacterial lipoprotein transporters

G. Privé, J. Klassen, C. Cairo, 2019, Communications Biology.

Galectin-3 alters the lateral mobility and clustering of β1-integrin receptors

C. Cairo, M. Eckermann, Md. Amran Howlader, 2017, PloS one.

Hitting the sweet spot

L. Kiessling, C. Cairo, 2002, Nature Biotechnology.

Interlaboratory Study on Differential Analysis of Protein Glycosylation by Mass Spectrometry: The ABRF Glycoprotein Research Multi-Institutional Study 2012*

Carthene R. Bazemore-Walker, Paula J. Griffin, H. Desaire, 2013, Molecular & Cellular Proteomics.

Hitting the sweet spot

Christopher W. Cairo, L. Kiessling, C. Cairo, 2002, Nature Biotechnology.

Substrate recognition of the membrane-associated sialidase NEU3 requires a hydrophobic aglycone.

D. Bundle, C. Cairo, John S. Klassen, 2011, Biochemistry.

Enhanced Cross-Linking of Diazirine-Modified Sialylated Glycoproteins Enabled through Profiling of Sialidase Specificities.

Jennifer J. Kohler, C. Cairo, J. McCombs, 2016, ACS chemical biology.

Severe kidney dysfunction in sialidosis mice reveals an essential role for neuraminidase 1 in reabsorption

A. Pshezhetsky, L. Sturiale, A. Palmigiano, 2023, JCI insight.

New insights into the glycobiology of immune thrombocytopenia

C. Cairo, D. Kuter, Katherine H. Tiemeyer, 2023, Current opinion in hematology.