E. Michaelis

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Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging

E. Michaelis, 1998, Progress in Neurobiology.

Direct measurement of glutamate release in the brain using a dual enzyme-based electrochemical sensor

G. S. Wilson, George S. Wilson, Elias K. Michaelis, 1994, Brain Research.

Integrating Multiple Microarray Data for Cancer Pathway Analysis Using Bootstrapping K-S Test

Xinkun Wang, Xue-Wen Chen, Elias K. Michaelis, 2009, Journal of biomedicine & biotechnology.

Comparison of the cycloheximide and food satiation effects on a discrimination task

E. Michaelis, J. Becker, 1977, Pharmacology Biochemistry and Behavior.

Oxidative inactivation of purified plasma membrane Ca2+-ATPase by hydrogen peroxide and protection by calmodulin.

M. Michaelis, C. Schöneich, E. Michaelis, 2003, Biochemistry.

Protein half-lives of calmodulin and the plasma membrane Ca-ATPase in rat brain.

D. Ferrington, E. Michaelis, D. Bigelow, 1997, Biochemical and biophysical research communications.

Fluorogenic tagging of protein 3-nitrotyrosine with 4-(aminomethyl)benzene sulfonate in tissues: a useful alternative to Immunohistochemistry for fluorescence microscopy imaging of protein nitration.

C. Schöneich, E. Michaelis, V. Sharov, 2012, Free radical biology & medicine.

Activation of brain calcineurin (Cn) by Cu-Zn superoxide dismutase (SOD1) depends on direct SOD1-Cn protein interactions occurring in vitro and in vivo.

E. Michaelis, A. Zaidi, A. Agbas, 2007, The Biochemical journal.

Isolation of Synaptosomes, Synaptic Plasma Membranes, and Synaptic Junctional Complexes.

M. Michaelis, E. Michaelis, Lei Jiang, 2017, Methods in molecular biology.

A Mitochondrial DNA Haplogroup Defines Patterns of Five-Year Cognitive Change.

J. Pa, R. Swerdlow, S. Andrews, 2022, Journal of Alzheimer's disease : JAD.

Spider venoms inhibit L-glutamate binding to brain synaptic membrane receptors.

E. Michaelis, N. Galton, S. Early, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Pharmacological specificity of synaptosomal and synaptic membrane gamma-aminobutyric acid (GABA) transport processes.

E. Michaelis, M. Mertes, S. Early, 1981, Biochemical pharmacology.

Oxaloacetate enhances neuronal cell bioenergetic fluxes and infrastructure

M. Michaelis, R. Swerdlow, S. Koppel, 2016, Journal of neurochemistry.

Partial purification and characterization of a glutamate-binding membrane glycoprotein from rat brain.

E. Michaelis, 1975, Biochemical and biophysical research communications.

Presence of proteins and glutamate as major constituents of the venom of the spider Araneus gemma.

E. Michaelis, S. Early, 1987, Toxicon : official journal of the International Society on Toxinology.

High affinity Ca2+-stimulated Mg2+-dependent ATPase in rat brain synaptosomes, synaptic membranes, and microsomes.

M. Michaelis, E. Michaelis, H. Chang, 1983, The Journal of biological chemistry.

Ca++ fluxes in resealed synaptic plasma membrane vesicles.

M. Michaelis, E. Michaelis, 1981, Life sciences.

Genome-wide transcriptome profiling of region-specific vulnerability to oxidative stress in the hippocampus.

Xue-wen Chen, E. Michaelis, Xinkun Wang, 2007, Genomics.

Effects of L-glutamic acid on synaptosomal and synaptic membrane Na+ fluxes and (Na+-K+)-ATPase.

E. Michaelis, H. Chang, 1980, The Journal of biological chemistry.

Antibodies Against the Bovine Brain Glutamate Binding Protein

E. Michaelis, S. Roy, 1984, Journal of neurochemistry.

Mitochondrial Electron Transfer Cascade Enzyme Activity Assessment in Cultured Neurons and Select Brain Regions

M. Michaelis, P. Krishnamurthy, E. Michaelis, 2019, Current protocols in toxicology.

Mitonuclear interactions influence Alzheimer’s disease risk

Alzheimer's Disease Neuroimaging Initiative, A. Goate, A. Gross, 2019, Neurobiology of Aging.

Ligand-Operated Membrane Channels: Calcium (Glutamate)

E. Michaelis, 2004 .

Effects of Chronic Ethanol Treatment on the Expression of Calcium Transport Carriers and NMDA/Glutamate Receptor Proteins in Brain Synaptic Membranes

M. Michaelis, E. Michaelis, Xingyu Chen, 1997, Journal of neurochemistry.

The 71 kDa glutamate-binding protein is increased in cerebellar granule cells after chronic ethanol treatment.

L. Snell, K. Iorio, B. Tabakoff, 1996, Brain research. Molecular brain research.

Effects of ethanol on NMDA receptors in brain: possibilities for Mg(2+)-ethanol interactions.

M. Michaelis, E. Michaelis, 1994, Alcoholism, clinical and experimental research.

Adenosine modulation of synaptosomal dopamine release.

M. Michaelis, E. Michaelis, M L Michaelis, 1979, Life sciences.

Frontiers in Aging Neuroscience Aging Neuroscience Review Article

Xinkun Wang, Elias K. Michaelis, E. Michaelis, 2022 .

Developmental expression of N-methyl-d-aspartate (NMDA)-induced neurotoxicity, NMDA receptor function, and the NMDAR1 and glutamate-binding protein subunits in cerebellar granule cells in primary cultures

M. Michaelis, E. Michaelis, Yue Xia, 1995, Neurochemical Research.

L-glutamate stimulation of Na+ efflux from brain synaptic membrane vesicles.

E. Michaelis, H. Chang, 1981, The Journal of biological chemistry.

Effects of acute and chronic ethanol intake on synaptosomal glutamate binding activity.

W. Freed, E. Michaelis, M. Mulvaney, 1978, Biochemical pharmacology.

Calcium Influx Through NMDA Receptors, Chronic Receptor Inhibition by Ethanol and 2‐Amino‐5‐Phosphonopentanoic Acid, and Receptor Protein Expression

D. Moore-Nichols, E. Michaelis, H. Nguyen, 1999, Journal of neurochemistry.

L-Glutamate effects on electrical potentials of synaptic plasma membrane vesicles.

E. Michaelis, H. Chang, 1982, Biochimica et biophysica acta.

Oxaloacetate activates brain mitochondrial biogenesis, enhances the insulin pathway, reduces inflammation and stimulates neurogenesis.

W. Brooks, M. Michaelis, R. Swerdlow, 2014, Human molecular genetics.

Multimembrane Carbon Fiber Electrodes for Physiological Measurements of Nitric Oxide

E. Michaelis, K. Mitchell, 1998 .

Effects of Depressant Drugs on Sodium-Calcium Exchange in Resealed Synaptic Membranes

M. Michaelis, E. Michaelis, 1985 .

Ethanol effects on synaptic glutamate receptor function and on membrane lipid organization

E. Michaelis, J. Zimbrick, S. Roy, 1983, Pharmacology Biochemistry and Behavior.

Alcohol effects on synaptic membrane calcium ion fluxes

M. Michaelis, E. Michaelis, T. Tehan, 1983, Pharmacology Biochemistry and Behavior.

Differential effects of metal ligands on synaptic membrane glutamate binding and uptake systems

M. Michaelis, E. Michaelis, R. Grubbs, 1982, Neurochemical Research.

Neuronal Glud1 (glutamate dehydrogenase 1) over-expressing mice: Increased glutamate formation and synaptic release, loss of synaptic activity, and adaptive changes in genomic expression

G. Gerhardt, K. Hascup, Y. Wang, 2011, Neurochemistry International.

Calcium binding to brain synaptosomes. Effects of chronic ethanol intake.

E. Michaelis, S. Myers, 1979, Biochemical pharmacology.

Effects of gangliosides on the activity of the plasma membrane Ca2+-ATPase.

M. Michaelis, R. Winefield, E. Michaelis, 2014, Biochimica et biophysica acta.

High-affinity glutamic acid binding to brain synaptic membranes.

M. Michaelis, E. Michaelis, L. L. Boyarsky, 1974, Biochimica et biophysica acta.

Effects of intraventricular glutamic acid on the acquisition, performance, and extinction of an operant response, and on general activity

W. Freed, E. Michaelis, 1976, Psychopharmacology.

Physico-Chemical Interactions between Alcohol and Biological Membranes

M. Michaelis, E. Michaelis, 1983 .

Cellular and Molecular Bases of Alcohol’s Teratogenic Effects

M. Michaelis, E. Michaelis, 1994, Alcohol health and research world.

Fetal alcohol exposure: cellular toxicity and molecular events involved in toxicity.

E. Michaelis, 1990, Alcoholism, clinical and experimental research.

Open Access Research Article Transcriptomic Responses in Mouse Brain Exposed to Chronic Excess of the Neurotransmitter Glutamate

E. Michaelis, Xinkun Wang, R. Pal, 2022 .

Anti-apoptotic protein Bcl-2 interacts with and destabilizes the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA).

C. Schöneich, E. Michaelis, V. Sharov, 2004, The Biochemical journal.

Classifying Aging Genes into DNA Repair or Non-DNA Repair-Related Categories

Jianwen Fang, Xinkun Wang, Yaping Fang, 2013, ICIC.

Transgenic Expression of Glud1 (Glutamate Dehydrogenase 1) in Neurons: In Vivo Model of Enhanced Glutamate Release, Altered Synaptic Plasticity, and Selective Neuronal Vulnerability

G. Gerhardt, M. Michaelis, K. Hascup, 2009, The Journal of Neuroscience.

Differential levels of glutamate dehydrogenase 1 (GLUD1) in Balb/c and C57BL/6 mice and the effects of overexpression of the Glud1 gene on glutamate release in striatum

G. Gerhardt, M. Michaelis, E. Hascup, 2011, ASN neuro.

Alcohol and local anesthetic effects on Na+-dependent Ca2+ fluxes in brain synaptic membrane vesicles.

M. Michaelis, E. Michaelis, Elias K. Michaelis, 1983, Biochemical pharmacology.

Two different families of NMDA receptors in mammalian brain: physiological function and role in neuronal development and degeneration.

E. Michaelis, 1993, Advances in experimental medicine and biology.

Effects of 2-chloroadenosine on electric potentials in brain synaptic membrane vesicles.

M. Michaelis, E. Michaelis, 1981, Biochimica et biophysica acta.

Gene expression patterns in the hippocampus during the development and aging of Glud1 (Glutamate Dehydrogenase 1) transgenic and wild type mice

E. Michaelis, M. Sayed-Ahmed, Xinkun Wang, 2014, BMC Neuroscience.

Concanavalin A binding to brain particulate preparations and its effect on adenylate cyclase.

M. Michaelis, E. Michaelis, 1976, Life sciences.

Effects of Ethanol Exposure on the Neurochemical Profile of a Transgenic Mouse Model with Enhanced Glutamate Release Using In Vivo 1H MRS

Phil Lee, E. Michaelis, I. Choi, 2018, Neurochemical Research.

Glutamic acid and ethanol dependence

W. Freed, E. Michaelis, 1978, Pharmacology Biochemistry and Behavior.

Genomic and biochemical approaches in the discovery of mechanisms for selective neuronal vulnerability to oxidative stress

M. Michaelis, Xue-wen Chen, E. Michaelis, 2009, BMC Neuroscience.

Metabolism Changes During Aging in the Hippocampus and Striatum of Glud1 (Glutamate Dehydrogenase 1) Transgenic Mice

W. Brooks, Phil Lee, E. Michaelis, 2014, Neurochemical Research.

Selective dendrite-targeting of mRNAs of NR1 splice variants without exon 5: identification of a cis-acting sequence and isolation of sequence-binding proteins

M. Michaelis, J. Hunt, E. Michaelis, 2003, Brain Research.

A synaptic membrane glycine-, glutamate- and thienylcyclohexylpiperidine-binding protein: isolation and immunochemical characterization

E. Michaelis, C. Decedue, Xingyu Chen, 1996, Neurochemistry International.

Vitroin the Laterodorsal Tegmental Nucleus In Activity-Dependent Nitric Oxide Concentration

R. Strecker, Ritchie E. Brown, R. Basheer, 2015 .

Activity-dependent nitric oxide concentration dynamics in the laterodorsal tegmental nucleus in vitro.

C. Leonard, E. Michaelis, K. Mitchell, 2001, Journal of neurophysiology.

Characterization of organophosphate interactions at N-methyl-D-aspartate receptors in brain synaptic membranes.

E. Michaelis, P. Johnson, 1992, Molecular pharmacology.

Localization of a gene for a glutamate binding subunit of a NMDA receptor (GRINA) to 8q24.

R. Leach, E. Michaelis, B. Dupont, 1996, Genomics.

Bioenergetic flux, mitochondrial mass and mitochondrial morphology dynamics in AD and MCI cybrid cell lines.

R. Swerdlow, J. Burns, E. Michaelis, 2013, Human molecular genetics.

High intrinsic oxidative stress may underlie selective vulnerability of the hippocampal CA1 region.

Xue-wen Chen, E. Michaelis, Nanteetip Limpeanchob, 2005, Brain research. Molecular brain research.

Superoxide modification and inactivation of a neuronal receptor-like complex.

E. Michaelis, K. N. Kumar, X. Chen, 2002, Free radical biology & medicine.

Exploratory analysis of mtDNA haplogroups in two Alzheimer's longitudinal cohorts

M. Michaelis, J. Pa, R. Swerdlow, 2020, Alzheimer's & dementia : the journal of the Alzheimer's Association.

TOMM40 '523 Associations with Baseline and Longitudinal Cognition in APOE ɛ3 Homozygotes.

R. Swerdlow, E. Michaelis, H. Wilkins, 2019, Journal of Alzheimer's disease : JAD.

Molecular aspects of glutamate receptors and sodium-calcium exchange carriers in mammalian brain: Implications for neuronal development and degeneration

M. Michaelis, E. Michaelis, 2004, Neurochemical Research.

Decreased activity and increased aggregation of brain calcineurin during aging

E. Michaelis, A. Zaidi, A. Agbas, 2005, Brain Research.

Glutamate receptor changes in brain synaptic membranes from human alcoholics

J. Kleinman, W. Freed, M. Michaelis, 1990, Neurochemical Research.

Decreases in plasma membrane Ca2+‐ATPase in brain synaptic membrane rafts from aged rats

M. Michaelis, E. Michaelis, T. Williams, 2012, Journal of neurochemistry.

Functional Genomics of Brain Aging and Alzheimer’s Disease: Focus on Selective Neuronal Vulnerability

Xinkun Wang, M. Michaelis, E. Michaelis, 2010, Current genomics.

Molecular and Functional Characterization of a Brain Neuronal Membrane Glutamate-Binding Protein

T. Stormann, E. Michaelis, S. Roy, 1988 .

Keeping up with Genome Sequence and Expression

Y. Hérault, M. Zhuo, I. Gut, 2014 .

The Dose—Response Model for Dioxin

L. Lasagna, D. Bylund, H. Swanson, 1998, Risk analysis : an official publication of the Society for Risk Analysis.

Developmental expression, compartmentalization, and possible role in excitotoxicity of a putative NMDA receptor protein in cultured hippocampal neurons

M. Mattson, E. Michaelis, Hong Wang, 1991, Brain Research.

Isolation of glutamate-binding proteins from rat and bovine brain synaptic membranes and immunochemical and immunocytochemical characterization

E. Michaelis, K. N. Kumar, H. Wang, 1992, Neuroscience.

Cloning of cDNA for the glutamate-binding subunit of an NMDA receptor complex

E. Michaelis, N. Tilakaratne, Peter S. Johnson, 1991, Nature.

NMDA treatment and K+-induced depolarization selectively promote the expression of an NMDA-preferring class of the ionotropic glutamate receptors in cerebellar granule neurones

R. Balázs, N. Hack, E. Michaelis, 1992, Neuroscience Letters.

Ion channel sensors for glutamic acid.

T. Kuwana, Y. Umezawa, E. Michaelis, 1991, Analytical chemistry.

Effects of Ethanol Exposure on the Neurochemical Profile of a Transgenic Mouse Model with Enhanced Glutamate Release Using In Vivo 1H MRS

Phil Lee, E. Michaelis, I. Choi, 2018, Neurochemical Research.

Characteristics of Mg2+-dependent, ATP-activated Ca2+ transport in synaptic and microsomal membranes and in permeabilized synaptosomes.

M. Michaelis, E. Michaelis, E. LeCluyse, 1987, The Journal of biological chemistry.

Immunochemical characterization of brain synaptic membrane glutamate-binding proteins.

E. Michaelis, M. Eaton, K. N. Kumar, 1990, The Journal of biological chemistry.

Immune labeling and purification of a 71-kDa glutamate-binding protein from brain synaptic membranes. Possible relationship of this protein to physiologic glutamate receptors.

E. Michaelis, J. Chen, N. Galton, 1988, The Journal of biological chemistry.

Effects of chronic alcohol administration on synaptic membrane Na+ Ca2+ exchange activity

M. Michaelis, E. Michaelis, N. Galton, 1987, Brain Research.

Selective Neuronal Vulnerability in the Hippocampus: Relationship to Neurological Diseases and Mechanisms for Differential Sensitivity of Neurons to Stress

Elias K. Michaelis, E. Michaelis, 2012 .

Effects of amphipathic drugs onl-[3H]glutamate binding to synaptic membranes and the purified binding protein

M. Michaelis, E. Michaelis, R. A. Lampe, 2004, Neurochemical Research.

Oxidative Stress Markers of Alzheimer's Disease in Peripheral Cell Mitochondria

C. Schöneich, E. Michaelis, Lei Jiang, 2017 .

Chronic ethanol exposure increases gene transcription of subunits of an N-methyl-d-aspartate receptor-like complex in cortical neurons in culture

E. Michaelis, D. Hui, X. Bao, 2001, Neuroscience Letters.

Immunocytochemical and in situ hybridization studies of the expression and distribution of three subunits of a complex with N-methyl-d-aspartate receptor-like properties

E. Michaelis, M. Eaton, K. N. Kumar, 1999, Neuroscience.

Purification and Molecular Characterization of the Brain Synaptic Membrane Glutamate‐Binding Protein

M. Michaelis, T. Stormann, E. Michaelis, 1983, Journal of neurochemistry.

Distinguishing characteristics between glutamate and kainic acid binding sites in brain synaptic membranes

M. Michaelis, E. Michaelis, R. Grubbs, 1980, FEBS letters.

Chronic ethanol intake and synaptosomal glutamate binding activity.

W. Freed, M. Michaelis, E. Michaelis, 1980, Advances in Experimental Medicine and Biology.

Depolarization-induced release of L-glutamic acid from isolated-resealed synaptic membrane vesicles.

E. Michaelis, H. Chang, 1984, Biochimica et biophysica acta.

An ion exchange chromatographic method for the determination of synaptosomal calcium uptake

M. Michaelis, E. Michaelis, Amy E. Simpson, 1982, Neurochemical Research.

Purification, Reconstitution, and Cloning of an NMDA Receptor‐Ion Channel Complex from Rat Brain Synaptic Membranes: Implications for Neurobiological Changes in Alcoholism a

M. Michaelis, Y. Umezawa, R. Schowen, 1992, Annals of the New York Academy of Sciences.

Correlation of glutamate binding activity with glutamate-binding protein immunoreactivity in the brain of control and alcohol-treated rats

M. Michaelis, E. Michaelis, E. LeCluyse, 1987, Neurochemistry International.

Ethanol effects on synaptic glutamate receptors and on liposomal membrane structure

M. Michaelis, E. Michaelis, J. Zimbrick, 1980, Pharmacology Biochemistry and Behavior.

Molecular Properties of an NMDA Receptor Complex and Effects of Ethanol on the Expression of this Complex

M. Michaelis, E. Michaelis, Keshava N. Kumar, 1993 .

Cloning of a BrainN-Methyl-d-Aspartate- andd,l-ϵ-2-Amino-4-propyl-5-phosphono-3-pentanoic Acid (CGP 39653)-Binding Protein

E. Michaelis, C. Bigge, Mushtaq Ahmad, 1998 .

Immunochemical and immunohistochemical characterization of a synaptic membrane protein that binds the competitive antagonists of NMDA receptors

E. Michaelis, K. N. Kumar, J. Walsh, 1993, Neuroscience Letters.

Effects of intracisternal GABA or glutamic acid upon behavioral activity in the rat

W. Freed, E. Michaelis, 1976, Pharmacology Biochemistry and Behavior.

Ion channel properties of a protein complex with characteristics of a glutamate/N‐methyl‐d‐aspartate receptor

R. Schowen, E. Michaelis, G. Aistrup, 1996, FEBS letters.

Solubilization and partial purification of 3-((+-)-2-carboxypiperazine-4-yl)-[1,2-3H]propyl-1-phosphonic acid recognition proteins from rat brain synaptic membranes.

E. Michaelis, M. Cunningham, M D Cunningham, 1990, The Journal of biological chemistry.

Ethanol‐Induced Inhibition of [3H]Thienylcyclohexylpiperidine (TCP) Binding to NMDA Receptors in Brain Synaptic Membranes and to a Purified Protein Complex

M. Michaelis, E. Michaelis, Xingyu Chen, 1996, Journal of neurochemistry.

Selective Neuronal Vulnerability to Oxidative Stress in the Brain

E. Michaelis, Xinkun Wang, 2010, Front. Ag. Neurosci..

A Rat Brain Bicistronic Gene with an Internal Ribosome Entry Site Codes for a Phencyclidine-binding Protein with Cytotoxic Activity*

K. Wanner, G. Höfner, E. Michaelis, 2009, Journal of Biological Chemistry.

Protein half-lives of two subunits of an NMDA receptor-like complex, the 71-kDa glutamate-binding and the 80-kDa CPP-binding protein.

D. Ferrington, E. Michaelis, D. Bigelow, 1997, Biochemical and biophysical research communications.

Selective neuronal vulnerability to oxidative stress in the brain

E. Michaelis, Xinkun Wang, Elias K. Michaelis, 2010 .

Selective neuronal vulnerability to oxidative stress in the brain

E. Michaelis, Xinkun Wang, Elias K. Michaelis, 2010 .

Molecular characteristics of glutamate receptors in the mammalian brain

M. Michaelis, E. Michaelis, R. Grubbs, 1981, Molecular and Cellular Biochemistry.

The glutamate receptor-like protein of brain synaptic membranes is a metalloprotein.

E. Michaelis, 1979, Biochemical and biophysical research communications.

Mapping of the human NMDA receptor subunit (NMDAR1) and the proposed NMDA receptor glutamate-binding subunit (NMDARA1) to chromosomes 9q34.3 and chromosome 8, respectively.

C. Collins, M. Hayden, A. Duncan, 1993, Genomics.

P3-197 Antiapoptotic protein BCL-2 interacts with and destabilizes the sarco/endoplasmic reticulum CA-ATPase (SERCA)

C. Schöneich, E. Michaelis, V. Sharov, 2004, Neurobiology of Aging.

Functional characteristics ofl-glutamate,N-methyl-d-aspartate and kainate receptors in isolated brain synaptic membranes

E. Michaelis, S. Roy, H. Chang, 1984, Neurochemical Research.

Glutamic Acid Synaptic Activity is a Target of Acute and Chronic Ethanol Effects in the Mammalian Brain

E. Michaelis, 1989 .

Ischemic tolerance in an in vivo model of glutamate preconditioning

Honglian Shi, E. Michaelis, R. Pal, 2015, Journal of neuroscience research.

Cloning of the cDNA for a brain glycine-, glutamate- and thienylcyclohexylpiperidine-binding protein.

E. Michaelis, M. Ahmad, P. Johnson, 1995, Biochemical and biophysical research communications.

Purification and pharmacological and immunochemical characterization of synaptic membrane proteins with ligand-binding properties of N-methyl-D-aspartate receptors.

E. Michaelis, P. Johnson, K. N. Kumar, 1994, The Journal of biological chemistry.