I. Smith

发表

SERCA pump activity is physiologically regulated by presenilin and regulates amyloid β production

F. LaFerla, I. Parker, Y. Akbari, 2008, The Journal of cell biology.

Shared functional defect in IP3R-mediated calcium signaling in diverse monogenic autism syndromes

J. Gargus, I. Parker, G. Schmunk, 2015, Translational Psychiatry.

Ca2+ Stores and capacitative Ca2+ entry in human neuroblastoma (SH-SY5Y) cells expressing a familial Alzheimer’s disease presenilin-1 mutation

R. Cowburn, C. Peers, P. Vaughan, 2002, Brain Research.

Lattice light sheet imaging of membrane nanotubes between human breast cancer cells in culture and in brain metastases

Kyle L Ellefsen, I. Parker, I. Smith, 2017, Scientific Reports.

Copyright © American Society for Investigative Pathology DOI: 10.2353/ajpath.2006.050593 Molecular Pathogenesis of Genetic and Inherited Diseases A Dynamic Relationship between Intracellular and Extracellular Pools of A�

F. LaFerla, A. Caccamo, S. Oddo, 2022 .

A dynamic relationship between intracellular and extracellular pools of Abeta.

F. LaFerla, A. Caccamo, S. Oddo, 2006, The American journal of pathology.

Spatial-temporal patterning of Ca2+ signals by the subcellular distribution of IP3 and IP3 receptors.

I. Parker, I. Smith, J. T. Lock, 2019, Seminars in cell & developmental biology.

Differential coupling of voltage-gated Ca2+ channels to catecholamine secretion from separate PC12 cell batches

C. Peers, K. Green, I. Smith, 2001, Neuroscience Letters.

Prion protein fragment 106-126 potentiates catecholamine secretion from PC-12 cells.

C. Peers, K. Green, I. Smith, 2001, American journal of physiology. Cell physiology.

Tunneling Nanotubes and Gap Junctions–Their Role in Long-Range Intercellular Communication during Development, Health, and Disease Conditions

M. D. Den Boer, N. Volkmann, D. Hanein, 2017, Front. Mol. Neurosci..

Hypoxic regulation of Ca2+ signalling in astrocytes and endothelial cells.

K. Porter, C. Peers, P. Aley, 2006, Advances in experimental medicine and biology.

Oxygen-induced DNA damage in freshly isolated brain cells compared with cultured astrocytes in the Comet assay.

E. Cemeli, Diana Anderson, J. Urenjak, 2003, Teratogenesis, carcinogenesis, and mutagenesis.

Representation of prefrontal axonal efferents in the thalamic nucleus reuniens in a rodent model of fetal alcohol exposure during third trimester

I. Smith, A. Klintsova, Zachary H. Gursky, 2022, Frontiers in Behavioral Neuroscience.

Communication of Ca(2+) signals via tunneling membrane nanotubes is mediated by transmission of inositol trisphosphate through gap junctions.

I. Parker, I. Smith, J. T. Lock, 2016, Cell calcium.

Active generation and propagation of Ca2+ signals within tunneling membrane nanotubes.

J. Shuai, I. Parker, I. Smith, 2011, Biophysical journal.

Chronic hypoxia remodels voltage-gated Ca2+ entry in a human airway chemoreceptor cell line

C. Peers, I. Smith, P. Kemp, 2002, Neuroscience Letters.

Imaging local Ca2+ signals in cultured mammalian cells.

Kyle L Ellefsen, I. Parker, I. Smith, 2015, Journal of visualized experiments : JoVE.

Imaging Local Ca 2 + Signals in Cultured Mammalian Cells

Kyle L Ellefsen, I. Parker, I. Smith, 2015 .

Calcium dysregulation in Alzheimer's disease: recent advances gained from genetically modified animals.

Frank M LaFerla, Kim N Green, F. LaFerla, 2005, Cell calcium.

Topic Introduction Fluorescence Microscopy

M. Sanderson, M. Bootman, I. Smith, 2014 .

A Novel Postsynaptic Mechanism for Heterosynaptic Sharing of Short-Term Plasticity

T. Carew, K. Reissner, I. Parker, 2010, The Journal of Neuroscience.

The Production of Amyloid β Peptide Is a Critical Requirement for the Viability of Central Neurons

C. Peers, I. Smith, J. Boyle, 2003, The Journal of Neuroscience.

SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production.

Ian Parker, Yama Akbari, Angelo Demuro, 2008, The Journal of general physiology.

A comparison of fluorescent Ca²⁺ indicators for imaging local Ca²⁺ signals in cultured cells.

Ian Parker, Jeffrey T Lock, I. Parker, 2015, Cell calcium.

An algorithm for automated detection, localization and measurement of local calcium signals from camera-based imaging.

Ian Parker, Brett Settle, Kyle L Ellefsen, 2014, Cell calcium.

Recording single-channel activity of inositol trisphosphate receptors in intact cells with a microscope, not a patch clamp

I. Parker, I. Smith, Ian Parker, 2010, The Journal of general physiology.

Role of calcium in the pathogenesis of Alzheimer's disease and transgenic models.

F. LaFerla, K. Green, I. Smith, 2007, Sub-cellular biochemistry.

Enhanced caffeine‐induced Ca2+ release in the 3xTg‐AD mouse model of Alzheimer's disease

F. LaFerla, S. Oddo, K. Green, 2005, Journal of neurochemistry.

Imaging the quantal substructure of single IP3R channel activity during Ca2+ puffs in intact mammalian cells

Ian Parker, I. Parker, I. Smith, 2009, Proceedings of the National Academy of Sciences.

Localization of puff sites adjacent to the plasma membrane: functional and spatial characterization of Ca2+ signaling in SH-SY5Y cells utilizing membrane-permeant caged IP3.

Ian Parker, I. Parker, I. Smith, 2009, Cell calcium.

Fluorescence microscopy.

M. Sanderson, M. Bootman, I. Smith, 2014, Cold Spring Harbor protocols.

Lattice light sheet imaging of membrane nanotubes between human breast cancer cells in culture and in brain metastases

Kyle L Ellefsen, I. Parker, I. Smith, 2017, Scientific Reports.

Hypoxic remodelling of Ca2+ mobilization in type I cortical astrocytes: involvement of ROS and pro‐amyloidogenic APP processing

C. Peers, K. Green, I. Smith, 2003, Journal of neurochemistry.

Ketamine sex- and dose-dependently mitigates behavioral sequelae induced by a predator-based psychosocial stress model of post-traumatic stress disorder

P. Zoladz, I. Smith, Cassandra S. Goodman, 2022, Behavioural Brain Research.

Superresolution localization of single functional IP3R channels utilizing Ca2+ flux as a readout.

I. Parker, I. Smith, Steven M. Wiltgen, 2010, Biophysical journal.

Single-molecule tracking of inositol trisphosphate receptors reveals different motilities and distributions.

I. Parker, I. Smith, George D. Dickinson, 2014, Biophysical journal.

Ca2+ Puffs Originate from Preestablished Stable Clusters of Inositol Trisphosphate Receptors

Ian Parker, Jianwei Shuai, J. Shuai, 2009, Science Signaling.

Timescales of IP(3)-evoked Ca(2+) spikes emerge from Ca(2+) puffs only at the cellular level.

Ian Parker, Martin Falcke, Kevin Thurley, 2011, Biophysical journal.

Comparison of Ca2+ puffs evoked by extracellular agonists and photoreleased IP3.

I. Parker, I. Smith, J. T. Lock, 2017, Cell calcium.

Glia-Driven Brain Circuit Refinement Is Altered by Early-Life Adversity: Behavioral Outcomes

I. Smith, A. Klintsova, Nicholas Collins, 2021, Frontiers in Behavioral Neuroscience.

Title SERCA pump activity is physiologically regulated by presenilin and regulates amyloid β production Permalink

F. LaFerla, I. Parker, Y. Akbari, 2022 .

Glucocorticoid Abnormalities in Female Rats Exposed to a Predator-Based Psychosocial Stress Model of PTSD

P. Zoladz, I. Smith, B. Rorabaugh, 2021, Frontiers in Behavioral Neuroscience.

Hypoxic Remodeling of Ca2+ Stores in Type I Cortical Astrocytes*

C. Peers, I. Smith, J. Boyle, 2003, The Journal of Biological Chemistry.

Hypoxic remodelling of Ca2+ homeostasis in rat type I cortical astrocytes.

C. Peers, I. Smith, J. Boyle, 2003, Advances in experimental medicine and biology.

Fluorescence microscopy.

M. Sanderson, M. Bootman, I. Smith, 2014, Cold Spring Harbor protocols.

Previously Published Works Uc Irvine Title: a Novel Postsynaptic Mechanism for Heterosynaptic Sharing of Short-term Plasticity a Novel Postsynaptic Mechanism for Heterosynaptic Sharing of Short-term Plasticity

T. Carew, K. Reissner, I. Parker, 2022 .

2 1 2 1 C a Stores and capacitative Ca entry in human neuroblastoma ( SH-SY 5 Y ) cells expressing a familial Alzheimer ’ s disease presenilin-1 mutation

R. Cowburn, C. Peers, P. Vaughan, 2002 .

Shared functional defect in IP3R-mediated calcium signaling in diverse monogenic autism syndromes

J. Gargus, I. Parker, G. Schmunk, 2015, Translational Psychiatry.

Communication of Ca(2+) signals via tunneling membrane nanotubes is mediated by transmission of inositol trisphosphate through gap junctions.

I. Parker, I. Smith, J. T. Lock, 2016, Cell calcium.

Fluorescence microscopy.

M. Sanderson, M. Bootman, I. Smith, 2014, Cold Spring Harbor Protocols.

Ca2+ Puffs Originate from Preestablished Stable Clusters of Inositol Trisphosphate Receptors

J. Shuai, I. Parker, I. Smith, 2009, Science Signaling.

Comparison of Ca2+ puffs evoked by extracellular agonists and photoreleased IP3.

I. Parker, I. Smith, J. T. Lock, 2017, Cell calcium.

Recording single-channel activity of inositol trisphosphate receptors in intact cells with a microscope, not a patch clamp

I. Parker, I. Smith, 2010, The Journal of general physiology.