Xiaochun Li

发表

Structure of a presenilin family intramembrane aspartate protease

Yigong Shi, Chuangye Yan, Xinqi Gong, 2012, Nature.

The V-motifs facilitate the substrate capturing step of the PTS elevator mechanism.

M. Saier, Jiawei Wang, Xiaochun Li, 2016, Journal of structural biology.

Long-term Proposal Report Structural Study of Regulated Intramembrane Proteolysis

N. Yan, Xiaochun Li, 2011 .

Triazoles inhibit cholesterol export from lysosomes by binding to NPC1

Akash Das, Joseph L. Goldstein, J. Goldstein, 2016, Proceedings of the National Academy of Sciences.

Birinapant, a smac-mimetic with improved tolerability for the treatment of solid tumors and hematological malignancies.

Yigong Shi, G. Kapoor, C. Day, 2014, Journal of medicinal chemistry.

Clues to the mechanism of cholesterol transfer from the structure of NPC1 middle lumenal domain bound to NPC2

G. Blobel, S. Pfeffer, Xiaochun Li, 2016, Proceedings of the National Academy of Sciences.

Structure of an integral membrane sterol reductase from Methylomicrobium alcaliphilum

G. Blobel, R. Roberti, Xiaochun Li, 2014, Nature.

Structural mechanisms of DIAP1 auto-inhibition and DIAP1-mediated inhibition of drICE.

Yigong Shi, Jiawei Wang, Xiaochun Li, 2011, Nature communications.

Structure and Mechanism of an Amino Acid Antiporter

Yigong Shi, Jiawei Wang, Xiaochun Li, 2009, Science.

Structure of human Niemann–Pick C1 protein

Hang Shi, G. Blobel, E. Coutavas, 2016, Proceedings of the National Academy of Sciences.

3.3 Å structure of Niemann–Pick C1 protein reveals insights into the function of the C-terminal luminal domain in cholesterol transport

G. Blobel, Jiawei Wang, Xiaochun Li, 2017, Proceedings of the National Academy of Sciences.

Difference distance map data of alternative crystal forms of UlaA

M. Saier, Jiawei Wang, Xiaochun Li, 2016, Data in brief.

Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage

Yigong Shi, Jiawei Wang, Xiaochun Li, 2009, Proceedings of the National Academy of Sciences.

Crystal structure of a phosphorylation-coupled vitamin C transporter

Jiawei Wang, Xiaochun Li, S. Fan, 2015, Nature Structural &Molecular Biology.

Structural biology of intramembrane proteases: mechanistic insights from rhomboid and S2P to γ-secretase.

Yigong Shi, Xiaochun Li, Linfeng Sun, 2016, Current opinion in structural biology.

The crystal structure of human phosphoglucose isomerase at 1.6 A resolution: implications for catalytic mechanism, cytokine activity and haemolytic anaemia.

J. Chirgwin, H. Muirhead, C. Davies, 2001, Journal of molecular biology.