J. West

发表

Interaction between Bone Morphogenetic Protein Receptor Type 2 and Estrogenic Compounds in Pulmonary Arterial Hypertension

J. Fessel, J. Loyd, A. Frump, 2013, Pulmonary circulation.

A potential role for insulin resistance in experimental pulmonary hypertension

L. Gleaves, J. Fessel, K. Niswender, 2012, European Respiratory Journal.

Experimental and transgenic models of pulmonary hypertension.

A. Hemnes, J. West, 2011, Comprehensive Physiology.

Neonatal lung side population cells demonstrate endothelial potential and are altered in response to hyperoxia-induced lung simplification.

David E. Irwin, J. Harral, D. Irwin, 2007, American journal of physiology. Lung cellular and molecular physiology.

Gene expression in BMPR2 mutation carriers with and without evidence of Pulmonary Arterial Hypertension suggests pathways relevant to disease penetrance

J. Cogan, J. Newman, J. Phillips, 2008, BMC Medical Genomics.

Expression of Mutant Bone Morphogenetic Protein Receptor II Worsens Pulmonary Hypertension Secondary to Pulmonary Fibrosis

L. Gleaves, J. Fessel, T. Blackwell, 2015, Pulmonary Circulation.

A potential therapeutic role for angiotensin-converting enzyme 2 in human pulmonary arterial hypertension

T. Rice, R. Gerszten, J. Newman, 2018, European Respiratory Journal.

The Selective Angiotensin II Type 2 Receptor Agonist, Compound 21, Attenuates the Progression of Lung Fibrosis and Pulmonary Hypertension in an Experimental Model of Bleomycin-Induced Lung Injury

G. Bedse, Ashok Kumar, M. Raizada, 2018, Front. Physiol..

BMP signaling controls PASMC KV channel expression in vitro and in vivo.

J. West, D. Rodman, M. Carr, 2006, American journal of physiology. Lung cellular and molecular physiology.

Unrecognized glucose intolerance is common in pulmonary arterial hypertension.

T. Rice, J. Newman, A. Hemnes, 2010, The Journal of Heart and Lung Transplantation.

Mechanisms of Lipid Accumulation in the Bone Morphogenetic Protein Receptor Type 2 Mutant Right Ventricle.

J. Newman, J. Fessel, E. Brittain, 2016, American journal of respiratory and critical care medicine.

Modification of Hemodynamic and Immune Responses to Exposure with a Weak Antigen by the Expression of a Hypomorphic BMPR2 Gene

Sung-Hyun Park, J. West, Wen-Chi Chen, 2013, PloS one.

The Endothelial Prolyl-4-Hydroxylase Domain 2/Hypoxia-Inducible Factor 2 Axis Regulates Pulmonary Artery Pressure in Mice

T. Fields, V. Haase, J. West, 2016, Molecular and Cellular Biology.

Whole Exome Sequencing to Identify a Novel Gene (Caveolin-1) Associated With Human Pulmonary Arterial Hypertension

W. Chung, A. Borczuk, Pavel Sumazin, 2012, Circulation. Cardiovascular genetics.

Saracatinib and Dasatinib Fail To Prevent Heritable Pulmonary Arterial Hypertension

S. Gladson, J. West, S. Shay, 2018, bioRxiv.

Microarray studies in pulmonary arterial hypertension

S. Menon, J. Fessel, J. West, 2011, International journal of clinical practice. Supplement.

Testosterone negatively regulates right ventricular load stress responses in mice

J. Newman, L. Gleaves, H. Champion, 2012, Pulmonary circulation.

A process-based review of mouse models of pulmonary hypertension

J. Fessel, Haiyang Tang, M. Das, 2012, Pulmonary circulation.

Dysfunctional BMPR2 signaling drives an abnormal endothelial requirement for glutamine in pulmonary arterial hypertension

Jamey D. Young, Robert A. Egnatchik, Thong Luong, 2017, Pulmonary circulation.

Interaction of interleukin-6 and the BMP pathway in pulmonary smooth muscle.

J. West, D. Rodman, W. Steudel, 2007, American journal of physiology. Lung cellular and molecular physiology.

Vildagliptin ameliorates pulmonary fibrosis in lipopolysaccharide-induced lung injury by inhibiting endothelial-to-mesenchymal transition

K. Tatsumi, S. Gladson, J. West, 2017, Respiratory Research.

Cross talk between Smad, MAPK, and actin in the etiology of pulmonary arterial hypertension.

J. West, 2010, Advances in experimental medicine and biology.

Xenoestrogen exposure and effects in English sole (Parophrys vetulus) from Puget Sound, WA.

Sean Y. Sol, L. Johnson, O. P. Olson, 2008, Aquatic toxicology.

Human PAH is characterized by a pattern of lipid-related insulin resistance.

R. Gerszten, Y. Shyr, J. Newman, 2019, JCI insight.

Overexpression of Msx1 in Mouse Lung Leads to Loss of Pulmonary Vessels Following Vascular Hypoxic Injury

Xinping Chen, J. West, S. Shay, 2021, Cells.

Peroxisome Proliferator‐Activated Receptor‐g Agonist Treatment Increases Septation and Angiogenesis and Decreases Airway Hyperresponsiveness in a Model of Experimental Neonatal Chronic Lung Disease

David E. Irwin, M. Koster, E. Nozik-Grayck, 2009, Anatomical record.

Impacts of caffeine on resistant chicken's performance and cardiovascular gene expression.

T. Niewold, J. West, M. K. Karimi Torshizi, 2021, Journal of animal physiology and animal nutrition.

Oestrogen inhibition reverses pulmonary arterial hypertension and associated metabolic defects

J. Fessel, J. Loyd, E. Farber-Eger, 2017, European Respiratory Journal.

NF-κB Activation Exacerbates, but Is not Required for Murine Bmpr2-Related Pulmonary Hypertension

T. Blackwell, W. Han, T. Blackwell, 2014 .

Evidence for right ventricular lipotoxicity in heritable pulmonary arterial hypertension.

L. Gleaves, J. Fessel, E. Brittain, 2014, American journal of respiratory and critical care medicine.

Inhalation of Stachybotrys chartarum Evokes Pulmonary Arterial Remodeling in Mice, Attenuated by Rho-Kinase Inhibitor

T. Toyotome, N. Tanabe, K. Tatsumi, 2011, Mycopathologia.

Enhanced caveolin-1 expression in smooth muscle cells: Possible prelude to neointima formation.

J. Loyd, R. Mathew, E. Austin, 2015, World journal of cardiology.

Upregulation of SERT and ADORA1 in broilers with acute right ventricular failure.

R. Wideman, J. West, M. K. Karimi Torshizi, 2017, Research in veterinary science.

Isolation and characterization of endothelial-to-mesenchymal transition cells in pulmonary arterial hypertension.

K. Tatsumi, E. J. Carrier, Xinping Chen, 2018, American journal of physiology. Lung cellular and molecular physiology.

BMPR2 mutation alters the lung macrophage endothelin-1 cascade in a mouse model and patients with heritable pulmonary artery hypertension.

B. Meyrick, J. Loyd, T. Blackwell, 2010, American journal of physiology. Lung cellular and molecular physiology.

BMPR 2 mutation alters the lung macrophage endothelin-1 cascade in a mouse model and patients with heritable pulmonary artery hypertension

B. Meyrick, J. Loyd, T. Blackwell, 2010 .

Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions.

D. Stewart, J. Harral, J. West, 2008, American journal of physiology. Lung cellular and molecular physiology.

Cytoskeletal defects in Bmpr2-associated pulmonary arterial hypertension.

J. Harral, M. Schuster, S. Gladson, 2012, American journal of physiology. Lung cellular and molecular physiology.

BMPR2 expression is suppressed by signaling through the estrogen receptor

John A. Phillips III, R. Hamid, J. Loyd, 2012, Biology of Sex Differences.

Idiopathic and heritable PAH perturb common molecular pathways, correlated with increased MSX1 expression

S. Menon, J. Cogan, J. Newman, 2011, Pulmonary circulation.

Serotonin transporter protein in pulmonary hypertensive rats treated with atorvastatin.

U. Christians, V. Schmitz, S. Trump, 2007, American journal of physiology. Lung cellular and molecular physiology.

Unrecognized glucose intolerance is common in pulmonary arterial hypertension.

T. Rice, J. Newman, A. Hemnes, 2010, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

Bone Marrow-derived Cells Contribute to Pathogenesis of Pulmonary Arterial Hypertension.

J. Cogan, R. Hamid, Ling Yan, 2015 .

Right ventricular systolic pressure measurements in combination with harvest of lung and immune tissue samples in mice.

Sung-Hyun Park, J. West, Wen-Chi Chen, 2013, Journal of visualized experiments : JoVE.

Role of BMPR2 Alternative Splicing in HPAH Penetrance Running title: Cogan et al.; Alternative splicing of BMPR2 and HPAH

R. Hamid, J. West, L. Hedges, 2012 .

Factors modulating the epithelial response to toxicants in tracheobronchial airways.

J. Lakritz, D. Hyde, J. West, 2001, Toxicology.

Abrogation of anti-inflammatory transcription factor LKLF in neutrophil-dominated airways.

S. Randell, K. Malcolm, J. Nick, 2008, American journal of respiratory cell and molecular biology.

Physiologic and molecular consequences of endothelial Bmpr2 mutation

E. Nozik-Grayck, J. Harral, K. Stenmark, 2011, Respiratory research.

Endothelial-to-mesenchymal transition in lipopolysaccharide-induced acute lung injury drives a progenitor cell-like phenotype.

K. Tatsumi, J. West, Fumiaki Kato, 2016, American journal of physiology. Lung cellular and molecular physiology.

Mice deficient in galectin-1 exhibit attenuated physiological responses to chronic hypoxia-induced pulmonary hypertension.

J. Harral, D. Irwin, James West, 2007, American journal of physiology. Lung cellular and molecular physiology.

Adverse physiologic effects of Western diet on right ventricular structure and function: role of lipid accumulation and metabolic therapy

V. Agrawal, E. Brittain, A. Hemnes, 2018, Pulmonary circulation.

BMP9 in Acute Respiratory Distress Syndrome: Decades of BMP Studies in Vascular Biology Paying Off?

J. West, 2021, American Journal of Respiratory and Critical Care Medicine.

Chasing Pulmonary Hypertension: 1980–2012

J. Newman, J. Phillips, R. Hamid, 2012 .

Gene expression in lungs of mice lacking the 5-hydroxytryptamine transporter gene

J. Harral, S. Eddahibi, J. West, 2009, BMC pulmonary medicine.

A bone-derived mixture of TGFβ-superfamily members forms a more mature vascular network than bFGF or TGF-β2 in vivo

J. Harral, J. West, W. Huffer, 2006, Angiogenesis.

Evidence for cell fusion is absent in vascular lesions associated with pulmonary arterial hypertension.

M. Skokan, J. Harral, K. Stenmark, 2008, American journal of physiology. Lung cellular and molecular physiology.

Copy-number variation in BMPR2 is not associated with the pathogenesis of pulmonary arterial hypertension

J. Cogan, J. Loyd, C. Vnencak-Jones, 2009, BMC Medical Genetics.

Low-Voltage-Activated (T-Type) Calcium Channels Control Proliferation of Human Pulmonary Artery Myocytes

J. Harral, L. Cribbs, J. West, 2005, Circulation research.

Resident mesenchymal vascular progenitors modulate adaptive angiogenesis and pulmonary remodeling via regulation of canonical Wnt signaling

Yuankai K. Tao, S. Menon, R. Sheridan, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Mechanistic Phase II Clinical Trial of Metformin in Pulmonary Arterial Hypertension

V. Agrawal, T. Rice, J. Newman, 2020, Journal of the American Heart Association.

NAPHTHALENE-INDUCED RESPIRATORY TRACT TOXICITY: METABOLIC MECHANISMS OF TOXICITY

R. Baldwin, D. Morin, C. Plopper, 2002, Drug metabolism reviews.

Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators

H. Moses, Agnieszka E. Gorska, J. West, 2011, Proceedings of the National Academy of Sciences.

Critical Genomic Networks and Vasoreactive Variants in Idiopathic Pulmonary Arterial Hypertension.

Zhongming Zhao, S. Rich, S. Archer, 2016, American journal of respiratory and critical care medicine.

Rescuing the BMPR2 signaling axis in pulmonary arterial hypertension.

R. Hamid, J. Fessel, J. Loyd, 2014, Drug discovery today.

Molecular effects of loss of BMPR2 signaling in smooth muscle in a transgenic mouse model of PAH.

J. Harral, T. Kuriyama, J. West, 2007, American journal of physiology. Lung cellular and molecular physiology.

Estrogen Metabolite 16&agr;-Hydroxyestrone Exacerbates Bone Morphogenetic Protein Receptor Type II–Associated Pulmonary Arterial Hypertension Through MicroRNA-29–Mediated Modulation of Cellular Metabolism

J. Cogan, J. Phillips, R. Hamid, 2016, Circulation.

Echocardiographic assessment of the right heart in mice.

E. Brittain, A. Hemnes, J. West, 2013, Journal of visualized experiments : JoVE.

Adverse effects of BMPR2 suppression in macrophages in animal models of pulmonary hypertension

Ling Yan, J. Loyd, Xinping Chen, 2020, Pulmonary circulation.

Are obliterative pulmonary vascular lesions reversible?

J. West, 2011, American journal of respiratory and critical care medicine.

ACE2 Improves Right Ventricular Function in a Pressure Overload Model

Jennifer A. Johnson, A. Hemnes, J. West, 2011, PloS one.

Oxidative injury is a common consequence of BMPR2 mutations

J. Fessel, L. Roberts, E. Austin, 2011, Pulmonary Circulation.

Oxidative injury is a common consequence of BMPR2 mutations.

J. Fessel, L. Roberts, E. Austin, 2010, Pulmonary circulation.

Cytoskeletal defects in Bmpr 2-associated pulmonary arterial hypertension

J. Harral, M. Schuster, S. Gladson, 2012 .

The Estrogen Metabolite 16 OHE Exacerbates BMPR 2-Associated PAH Through miR-29-Mediated Modulation of Cellular Metabolism

J. Cogan, J. Phillips, R. Hamid, 2015 .

Machine learning-based microarray analyses indicate low-expression genes might collectively influence PAH disease

Qiang Wu, Song Cui, James West, 2019, PLoS Comput. Biol..

A bone-derived mixture of TGF beta-superfamily members forms a more mature vascular network than bFGF or TGF-beta 2 in vivo.

J. Harral, J. West, W. Huffer, 2005, Angiogenesis.

Alterations in oestrogen metabolism: implications for higher penetrance of familial pulmonary arterial hypertension in females

F. Parl, J. Cogan, J. Cogan, 2009, European Respiratory Journal.

Hypoxia Mediates Mutual Repression between microRNA-27a and PPARγ in the Pulmonary Vasculature

B. Kang, C. Hart, J. West, 2013, PloS one.

Bmc Pulmonary Medicine Gene Expression in Lungs of Mice Lacking the 5-hydroxytryptamine Transporter Gene

J. Harral, S. Eddahibi, J. West, 2009 .

Human PAH is characterized by a pattern of lipid-related insulin resistance.

Y. Shyr, J. Fessel, J. Wharton, 2019, JCI insight.