Mallika Alvala

发表

Antimicrobial Peptides: A Promising Therapeutic Strategy in Tackling Antimicrobial Resistance.

A. Saraswati, R. Nuti, N. S. Goud, 2017, Current medicinal chemistry.

Molecular dynamic simulations reveal suboptimal binding of salbutamol in T164I variant of β2 adrenergic receptor

S. Singh, Mallika Alvala, A. Nayarisseri, 2017, PloS one.

Synthesis and biological evaluation of pyrrolo[2,3-b]pyridine analogues as antiproliferative agents and their interaction with calf thymus DNA.

N. Jain, Mallika Alvala, Suresh Narva, 2016, European journal of medicinal chemistry.

Design and synthesis of β-carboline linked aryl sulfonyl piperazine derivatives: DNA topoisomerase II inhibition with DNA binding and apoptosis inducing ability.

Arunasree M. Kalle, N. Nagesh, Mallika Alvala, 2020, Bioorganic chemistry.

Anticancer activity of Pupalia lappacea on chronic myeloid leukemia K562 cells

Arunasree M. Kalle, Mallika Alvala, A. Ravi, 2012, DARU Journal of Pharmaceutical Sciences.

Non-carbohydrate strategies to inhibit lectin proteins with special emphasis on galectins.

Mallika Alvala, Aaftaab Sethi, Swetha Sanam, 2021, European journal of medicinal chemistry.

An updated patent review of galectin-1 and galectin-3 inhibitors and their potential therapeutic applications (2016–present)

Ravi Alvala, Mallika Alvala, Aaftaab Sethi, 2021, Expert opinion on therapeutic patents.

Association of Transforming Growth Factor-Beta 1 Promoter Variant -509 C/T with Bronchial Asthma in South Indian Population

Mallika Alvala, S. Bandaru, H. Mundluru, 2014, Inflammation.

Design, synthesis and computational studies involving Indole-Coumarin hybrids as galectin-1 inhibitors

V. Talla, I. Qureshi, Mallika Alvala, 2021, Chemical Papers.

Sequential coupling/desilylation-coupling/cyclization in a single pot under Pd/C-Cu catalysis: synthesis of 2-(hetero)aryl indoles.

J. Iqbal, M. Pal, Mallika Alvala, 2011, Organic & biomolecular chemistry.

Embelin Alleviates Severe Airway Inflammation in OVA-LPS-Induced Rat Model of Allergic Asthma

S. Gan, Mallika Alvala, M. Sekar, 2021, Journal of asthma and allergy.

Identification of high affinity bioactive Salbutamol conformer directed against mutated (Thr164Ile) beta 2 adrenergic receptor.

Mallika Alvala, A. Nayarisseri, S. Bandaru, 2015, Current topics in medicinal chemistry.

Identification and characterization of novel indole based small molecules as anticancer agents through SIRT1 inhibition.

P. Yogeeswari, D. Sriram, Mallika Alvala, 2013, European journal of medicinal chemistry.

Synthesis of various 3-nitropropionamides as Mycobacterium tuberculosis isocitrate lyase inhibitor.

P. Yogeeswari, D. Sriram, Mallika Alvala, 2011, Bioorganic & medicinal chemistry letters.

Ethylenediamine diacetate (EDDA) mediated synthesis of aurones under ultrasound: their evaluation as inhibitors of SIRT1.

M. Pal, Mallika Alvala, Naveen Mulakayala, 2012, Bioorganic & medicinal chemistry letters.

New clues arising from hunt of saccharides binding to galectin 3 via 3D QSAR and docking studies

Mallika Alvala, Aaftaab Sethi, Swetha Sanam, 2020 .

Synthesis and biological evaluation of novel 4, 7-disubstituted coumarins as selective tumor-associated carbonic anhydrase IX and XII inhibitors.

C. Supuran, K. Chandra, A. Angeli, 2021, Bioorganic & medicinal chemistry letters.

MEMES: Machine learning framework for Enhanced MolEcular Screening

Yashaswi Pathak, U Deva Priyakumar, Siddhartha Laghuvarapu, 2021, Chemical science.

Discovery of 4-sulfamoyl-phenyl-β-lactams as a new class of potent carbonic anhydrase isoforms I, II, IV and VII inhibitors: The first example of subnanomolar CA IV inhibitors.

S. M. Monti, A. Angeli, Mallika Alvala, 2017, Bioorganic & medicinal chemistry.

Anti-proliferative activity, molecular modeling studies and interaction with calf thymus DNA of novel ciprofloxacin analogues

Mallika Alvala, M. Bhadra, Kondapalli Venkata Gowri Chandra Sekhar, 2018, Proceedings of the Indian Academy of sciences. Chemical sciences.

Synthesis, molecular docking simulation, and biological evaluation studies of novel amide and ether conjugates of 2,3‐diaryl‐1,3‐thiazolidin‐4‐ones

N. S. Goud, Mallika Alvala, Estari Mamidala, 2020 .

Design, Synthesis, and Biological Evaluation of 2-(4-Aminophenyl)benzothiazole Analogues as Antiproliferative Agents

N. Jain, Mallika Alvala, D. Bhattacharjee, 2018, Journal of Heterocyclic Chemistry.

Transition metal mediated construction of pyrrole ring on 2,3-dihydroquinolin-4(1H)-one: synthesis and pharmacological evaluation of novel tricyclic heteroarenes.

J. Iqbal, K. Mukkanti, M. Pal, 2011, Organic & biomolecular chemistry.

A metal-free approach for the synthesis of amides/esters with pyridinium salts of phenacyl bromides via oxidative C–C bond cleavage

Mallika Alvala, Yellaiah Tangella, N. H. Krishna, 2019, Beilstein journal of organic chemistry.

Discovery and Structure Optimization of a Series of Isatin Derivatives as Mycobacterium tuberculosis Chorismate Mutase Inhibitors

P. Yogeeswari, D. Sriram, Reshma Alokam, 2014, Chemical biology & drug design.

Mycobacterium tuberculosis chorismate mutase: A potential target for TB.

R. K. Patel, Gopalakrishnan Bulusu, M. Pal, 2017, Bioorganic & medicinal chemistry.

Identification and structure–activity relationship study of carvacrol derivatives as Mycobacterium tuberculosis chorismate mutase inhibitors

P. Yogeeswari, D. Sriram, Reshma Alokam, 2014, Journal of enzyme inhibition and medicinal chemistry.

Novel acridinedione derivatives: design, synthesis, SIRT1 enzyme and tumor cell growth inhibition studies.

P. Yogeeswari, D. Sriram, Shubhmita Bhatnagar, 2012, Bioorganic & medicinal chemistry letters.

Development of 5-nitrothiazole derivatives: identification of leads against both replicative and latent Mycobacterium tuberculosis.

P. Yogeeswari, D. Sriram, Mallika Alvala, 2012, Bioorganic & medicinal chemistry letters.

Synthesis and Biological Evaluation of Novel Heterocyclic Imines Linked Coumarin-Thiazole Hybrids as Anticancer Agents.

V. Talla, I. Qureshi, N. S. Goud, 2019, Anti-Cancer Agents in Medicinal Chemistry.

Synthesis and biological evaluation of imidazo[1,5-a]pyridine-benzimidazole hybrids as inhibitors of both tubulin polymerization and PI3K/Akt pathway.

Mallika Alvala, A. Kamal, A. S. Rao, 2014, Organic & biomolecular chemistry.

Design and synthesis of 4-morpholino-6-(1,2,3,6-tetrahydropyridin-4-yl)-N-(3,4,5-trimethoxyphenyl)-1,3,5-triazin-2-amine analogues as tubulin polymerization inhibitors.

N. Jain, Mallika Alvala, B. B. Rao, 2017, Bioorganic & medicinal chemistry letters.

Synthesis and Biological Evaluation of Imidazo[2,1-b]Thiazole based Sulfonyl Piperazines as Novel Carbonic Anhydrase II Inhibitors

C. Supuran, A. Angeli, Mallika Alvala, 2020, Metabolites.

Design, synthesis and evaluation of small molecule reactive oxygen species generators as selective Mycobacterium tuberculosis inhibitors.

P. Yogeeswari, D. Sriram, H. Chakrapani, 2012, Chemical communications.

Synthesis and biological evaluation of coumarin-1,3,4-oxadiazole hybrids as selective carbonic anhydrase IX and XII inhibitors.

C. Supuran, A. Angeli, Mallika Alvala, 2019, Bioorganic chemistry.

Design, synthesis and biological evaluation of coumarin-3-carboxamides as selective carbonic anhydrase IX and XII inhibitors.

C. Supuran, A. Angeli, Mallika Alvala, 2019, Bioorganic chemistry.

Structure‐Guided Design of Thiazolidine Derivatives as Mycobacterium tuberculosis Pantothenate Synthetase Inhibitors

P. Yogeeswari, D. Sriram, Shalini Saxena, 2014, ChemMedChem.

Novel benzimidazole-triazole hybrids as apoptosis inducing agents in lung cancer: Design, synthesis, 18F-radiolabeling & galectin-1 inhibition studies.

I. Qureshi, Ravi Alvala, Mallika Alvala, 2020, Bioorganic chemistry.

Synthesis of 1-benzyl-1H-benzimidazoles as galectin-1 mediated anticancer agents.

V. Talla, I. Qureshi, N. S. Goud, 2019, Bioorganic chemistry.

Design and synthesis of 9H‐fluorenone based 1,2,3‐triazole analogues as Mycobacterium tuberculosis InhA inhibitors

Mallika Alvala, K. C. Chandra Sekhar, Amaroju Suresh, 2018, Chemical biology & drug design.

Cytotoxic constituents of Abutilon indicum leaves against U87MG human glioblastoma cells

Mallika Alvala, Y. Fujimoto, P. Rao, 2015, Natural product research.

Molecular Docking in Modern Drug Discovery: Principles and Recent Applications

K. Sasikala, Aaftaab Sethi, Khusbhoo Joshi, 2019, Drug Discovery and Development - New Advances.

Structure-based drug design of small molecule SIRT1 modulators to treat cancer and metabolic disorders.

P. Yogeeswari, D. Sriram, Mallika Alvala, 2014, Journal of molecular graphics & modelling.

Analysis of ADRB2 (Arg16Gly) Gene Variant with Susceptibility, Pharmacogenetic Response and Disease Severity in South Indian Asthmatics

Mallika Alvala, S. Bandaru, H. Mundluru, 2015, Inflammation.

Synthesis and biological evaluation of morpholines linked coumarin–triazole hybrids as anticancer agents

I. Qureshi, N. S. Goud, Ravi Alvala, 2019, Chemical biology & drug design.

Synthesis of Substituted Cinnamido Linked Quinazolinone Congeners as Potential Anticancer Agents via Mitochondrial Dependent Intrinsic Apoptotic Pathway.

Mallika Alvala, M. Saifi, C. Godugu, 2020, Anti-cancer agents in medicinal chemistry.

Synthesis and biological evaluation of some coumarin hybrids as selective carbonic anhydrase IX and XII inhibitors.

C. Supuran, A. Angeli, Mallika Alvala, 2020, Bioorganic chemistry.

Synthesis and exploration of 2-morpholino-4-phenylthiazol-5-yl acrylamide derivatives for their effects against carbonic anhydrase I, II, IX and XII isoforms as a non-sulfonamide class of inhibitors.

C. Supuran, A. Angeli, Priti Singh, 2019, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of phenyl-amino-pyrimidine and indole/oxindole conjugates as potential BCR-ABL inhibitors

Ramars Amanchy, A. Kamal, B. Sridhar, 2019, Medicinal Chemistry Research.

Human Galectin-1 and its inhibitors: Privileged target for cancer and HIV.

Ravi Alvala, Mallika Alvala, D. Komal, 2019, Mini reviews in medicinal chemistry.

Synthesis, 18F-radiolabeling and apoptosis inducing studies of novel 4, 7-disubstituted coumarins.

R. Bharath, I. Qureshi, N. S. Goud, 2020, Bioorganic chemistry.

Identification of Small Molecule as a High Affinity β2 Agonist Promiscuously Targeting Wild and Mutated (Thr164Ile) β 2 Adrenergic Receptor in the Treatment of Bronchial Asthma.

S. Singh, Mallika Alvala, A. Nayarisseri, 2016, Current pharmaceutical design.

Piperlongumine, an alkaloid causes inhibition of PI3 K/Akt/mTOR signaling axis to induce caspase-dependent apoptosis in human triple-negative breast cancer cells

Mallika Alvala, S. Ramakrishna, Dinesh Thummuri, 2014, Apoptosis.

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

Mallika Alvala, S. Jayanthi, Aaftaab Sethi, 2020, RSC advances.

Piperlongumine, an alkaloid causes inhibition of PI3 K/Akt/mTOR signaling axis to induce caspase-dependent apoptosis in human triple-negative breast cancer cells

Mallika Alvala, S. Ramakrishna, Dinesh Thummuri, 2014, Apoptosis.

Can targeting SIRT-1 to treat type 2 diabetes be a good strategy? A review

P. Yogeeswari, D. Sriram, Mallika Alvala, 2012, Expert opinion on therapeutic targets.

Scientific evidence for traditional claim of anti-obesity activity of Tecomella undulata bark.

Ravi Alvala, Mallika Alvala, V. Sama, 2013, Journal of ethnopharmacology.

Novel trisaccharide based phospholipids as immunomodulators.

S. Muller, Mallika Alvala, S. Bonam, 2019, International immunopharmacology.

Association of Transforming Growth Factor-Beta 1 Promoter Variant -509 C/T with Bronchial Asthma in South Indian Population

Mallika Alvala, S. Bandaru, H. Mundluru, 2015, Inflammation.

Enhanced Sampling of Chemical Space for High Throughput Screening Applications using Machine Learning

U. D. Priyakumar, Mallika Alvala, Yashaswi Pathak, 2021 .

Design and synthesis of substituted (1-(benzyl)-1H-1,2,3-triazol-4-yl)(piperazin-1-yl)methanone conjugates: study on their apoptosis inducing ability and tubulin polymerization inhibition.

N. Nagesh, Mallika Alvala, C. Godugu, 2020, RSC medicinal chemistry.

An efficient and facile green synthesis of bisindole methanes as potential Mtb FtsZ inhibitors

M. Doble, N. S. Goud, Mallika Alvala, 2018, Chemical biology & drug design.

Unraveling the peculiarities and development of novel inhibitors of leishmanial arginyl‐tRNA synthetase

I. Qureshi, Mallika Alvala, F. Nasim, 2024, The FEBS journal.

Design and synthesis of novel coumarin-benzimidazole hybrids as human galectin-1 inhibitors.

Arunasree M. Kalle, Ravi Alvala, Mallika Alvala, 2024, Future medicinal chemistry.