A. Cartmell

发表

Complex pectin metabolism by gut bacteria reveals novel catalytic functions

B. Henrissat, R. Field, S. Nepogodiev, 2017, Nature.

Complex pectin metabolism by gut bacteria reveals novel catalytic functions

B. Henrissat, R. Field, S. Nepogodiev, 2017, Nature.

A single bacterial sulfatase is required for metabolism of colonic mucin O-glycans and intestinal colonization by a symbiotic human gut bacterium

James A. London, P. Eyers, G. Michel, 2020, bioRxiv.

Insights into SusCD-mediated glycan import by a prominent gut symbiont

C. Robinson, N. Ranson, A. Mazur, 2021, Nature communications.

Insights into glycan import by a prominent gut symbiont

C. Robinson, N. Ranson, A. Mazur, 2020, bioRxiv.

Mobility shift-based electrophoresis coupled with fluorescent detection enables real-time enzyme analysis of carbohydrate sulfatase activity

James A. London, P. Eyers, D. Byrne, 2020, bioRxiv.

Sulfated glycan recognition by carbohydrate sulfatases of the human gut microbiota

James A. London, P. Eyers, D. Byrne, 2022, Nature Chemical Biology.

Structural and functional analyses of glycoside hydrolase 138 enzymes targeting chain A galacturonic acid in the complex pectin rhamnogalacturonan II

R. Field, S. Nepogodiev, J. Munoz-Munoz, 2019, The Journal of Biological Chemistry.

Structural studies of the unusual metal-ion site of the GH124 endoglucanase from Ruminiclostridium thermocellum

F. Liu, G. Davies, P. Walton, 2018, Acta crystallographica. Section F, Structural biology communications.

Sulfated glycan recognition by carbohydrate sulfatases of the human gut microbiota

James A. London, P. Eyers, D. Byrne, 2022, Nature Chemical Biology.

The human gut microbe Bacteroides thetaiotaomicron encodes the founding member of a novel glycosaminoglycan-degrading polysaccharide lyase family PL29

B. Henrissat, D. Ndeh, A. Cartmell, 2018, The Journal of Biological Chemistry.

A phase 2 study of pegylated liposomal doxorubicin, bortezomib, dexamethasone and lenalidomide for patients with relapsed/refractory multiple myeloma

C. Chen, A. Cartmell, J. Berenson, 2012, Leukemia.

Sulfated glycan recognition by carbohydrate sulfatases of the human gut microbiota

James A. London, P. Eyers, D. Byrne, 2022, Nature Chemical Biology.

Mining the human gut microbiome identifies mycobacterial D-arabinan degrading enzymes

Spencer J. Williams, B. Henrissat, L. Kiessling, 2022, bioRxiv.

Corrigendum: Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism

Spencer J. Williams, A. Thompson, H. Gilbert, 2015, Nature.

Exploration of expanded carbohydrate chemical space to access biological activity using microwave-induced acid condensation of simple sugars

James A. London, E. Yates, A. Cartmell, 2022, RSC advances.

Mitoxantrone and Paclitaxel Combination Chemotherapy in Metastatic Breast Cancer

W. Urba, R. Ghalie, A. Cartmell, 2001, Cancer investigation.

Recognition of xyloglucan by the crystalline cellulose‐binding site of a family 3a carbohydrate‐binding module

Mercedes C. Hernández-Gómez, Maja G. Rydahl, H. Gilbert, 2015, FEBS letters.

Improved prevention of moderately emetogenic chemotherapy‐induced nausea and vomiting with palonosetron, a pharmacologically novel 5‐HT3 receptor antagonist

J. Hajdenberg, A. Macciocchi, A. Cartmell, 2003, Cancer.

Correction

A. Cartmell, 2008 .

A phase 2 safety study of accelerated elotuzumab infusion, over less than 1 h, in combination with lenalidomide and dexamethasone, in patients with multiple myeloma

R. Rifkin, A. Cartmell, J. Berenson, 2017, American journal of hematology.

Functions and specificity of bacterial carbohydrate sulfatases targeting host glycans

E. Yates, A. Cartmell, A. Luis, 2022, Essays in biochemistry.

Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism

Eric C. Martens, Harry J. Gilbert, Andrew J. Thompson, 2015, Nature.

Corrigendum: Evidence for a Boat Conformation at the Transition State of GH76 α-1,6-Mannanases--Key Enzymes in Bacterial and Fungal Mannoprotein Metabolism.

Spencer J. Williams, A. Thompson, H. Gilbert, 2015, Angewandte Chemie.

Evidence for a boat conformation at the transition state of GH76 α-1,6-mannanases--key enzymes in bacterial and fungal mannoprotein metabolism.

Spencer J. Williams, A. Thompson, H. Gilbert, 2015, Angewandte Chemie.

The Structure and Function of an Arabinan-specific α-1,2-Arabinofuranosidase Identified from Screening the Activities of Bacterial GH43 Glycoside Hydrolases*

H. Brumer, J. Marles-Wright, R. Lewis, 2011, The Journal of Biological Chemistry.

An evolutionarily distinct family of polysaccharide lyases removes rhamnose capping of complex arabinogalactan proteins

Bernard Henrissat, Nicolas Terrapon, Harry J. Gilbert, 2017, The Journal of Biological Chemistry.

The Active Site of a Carbohydrate Esterase Displays Divergent Catalytic and Noncatalytic Binding Functions

E. Dodson, D. Bolam, H. Gilbert, 2009, PLoS biology.

Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides

B. Henrissat, H. Gilbert, K. Stott, 2017, Nature Microbiology.

A single sulfatase is required to access colonic mucin by a gut bacterium

James A. London, P. Eyers, G. Michel, 2021, Nature.

The Cellvibrio japonicus Mannanase CjMan26C Displays a Unique exo-Mode of Action That Is Conferred by Subtle Changes to the Distal Region of the Active Site*

H. Gilbert, G. Davies, E. Topakas, 2008, Journal of Biological Chemistry.

Metabolism of multiple glycosaminoglycans by Bacteroides thetaiotaomicron is orchestrated by a versatile core genetic locus

B. Henrissat, E. Yates, A. Baslé, 2020, Nature Communications.

Clinical benefit of trastuzumab (H) among patients with HER2-positive metastatic breast cancer (MBC) not achieving objective responses when treated with H plus chemotherapy (CT)

B. Leyland-Jones, W. Eiermann, P. Klein, 2004 .

Structure and function of novel cellulosic, hemicellulosic and pectic glycoside hydrolases

A. Cartmell, 2011 .

CHAMPION-1: a phase 1/2 study of once-weekly carfilzomib and dexamethasone for relapsed or refractory multiple myeloma.

R. Moss, R. Rifkin, Y. Ou, 2016, Blood.

Sulfated host glycan recognition by carbohydrate sulfatases of the human gut microbiota

James A. London, P. Eyers, D. Byrne, 2021, bioRxiv.

How members of the human gut microbiota overcome the sulfation problem posed by glycosaminoglycans

Vincent Lombard, Bernard Henrissat, Nicolas Terrapon, 2017, Proceedings of the National Academy of Sciences.

Combination therapy for chemotherapy-induced nausea and vomiting in patients receiving moderately emetogenic chemotherapy: palonosetron, dexamethasone, and aprepitant.

J. Hajdenberg, A. Cartmell, T. Grote, 2006, The journal of supportive oncology.

Engineering a surface endogalactanase into Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation

Spencer J. Williams, B. Henrissat, H. Gilbert, 2018, Nature Microbiology.

Analysis of the structural and functional diversity of plant cell wall specific family 6 carbohydrate binding modules.

B. Henrissat, P. Coutinho, H. Gilbert, 2009, Biochemistry.

Unusual active site location and catalytic apparatus in a glycoside hydrolase family

Bernard Henrissat, Nicolas Terrapon, B. Henrissat, 2017, Proceedings of the National Academy of Sciences.

Author Correction: A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation

Spencer J. Williams, B. Henrissat, H. Gilbert, 2019, Nature Microbiology.

Identification of d-arabinan-degrading enzymes in mycobacteria

Spencer J. Williams, B. Henrissat, L. Kiessling, 2023, Nature communications.

Replacement of ixazomib for relapsed/refractory multiple myeloma patients refractory to a bortezomib or carfilzomib-containing combination therapy.

R. Moss, T. Spektor, A. Cartmell, 2017 .

Structural insights into a unique cellulase fold and mechanism of cellulose hydrolysis

E. Bayer, H. Gilbert, M. Romão, 2011, Proceedings of the National Academy of Sciences.

Bortezomib, ascorbic acid and melphalan (BAM) therapy for patients with newly diagnosed multiple myeloma: an effective and well‐tolerated frontline regimen

A. Cartmell, J. Berenson, D. Woytowitz, 2009, European journal of haematology.

A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation

Spencer J. Williams, B. Henrissat, H. Gilbert, 2018, Nature Microbiology.

A new glycoside hydrolase family reveals a novel catalytic 2 apparatus and active site location for beta-propeller enzymes

B. Henrissat, H. Gilbert, J. Munoz-Munoz, 2017 .

Probing the beta-1,3:1,4 glucanase, CtLic26A, with a thio-oligosaccharide and enzyme variants.

H. Gilbert, G. Davies, C. Fontes, 2008, Organic & biomolecular chemistry.

Bortezomib, Ascorbic Acid and Melphalan (BAM) Therapy for Patients (pts) with Newly Diagnosed Multiple Myeloma (MM): An Effective and Well-Tolerated Frontline Regimen.

A. Cartmell, J. Berenson, D. Woytowitz, 2007 .

Metabolism of multiple glycosaminoglycans by Bacteroides thetaiotaomicron is orchestrated by a versatile core genetic locus

B. Henrissat, E. Yates, A. Baslé, 2020, Nature Communications.

Bortezomib, ascorbic acid and melphalan (BAM) therapy for patients with newly diagnosed multiple myeloma: an effective and well‐tolerated frontline regimen

A. Cartmell, J. Berenson, D. Woytowitz, 2009, European journal of haematology.

Updated results from CHAMPION-1, a phase I/II study investigating weekly carfilzomib with dexamethasone for patients (Pts) with relapsed or refractory multiple myeloma (RRMM).

R. Rifkin, A. Cartmell, J. Berenson, 2015 .