D. Knight

发表

Comparisons between electromagnetic and X-beam transit-time flow measurements for evaluating drug actions on cardiac output in the conscious dog.

D. Raunig, D. Flynn, E. Wolfgang, 2006, Journal of pharmacological and toxicological methods.

Measurement of organ blood flow with coloured microspheres in the rat.

Matthew W. Miller, M. Miller, D. Knight, 1995, Cardiovascular research.

2 – Cardiovascular Surgery for Chronic Experimentation in Conscious Animals

S. Vatner, D. Knight, 1986 .

A novel sodium-hydrogen exchanger isoform-1 inhibitor, zoniporide, reduces ischemic myocardial injury in vitro and in vivo.

R. J. Hill, D. Flynn, D. Knight, 2001, The Journal of pharmacology and experimental therapeutics.

The Sulfonylurea Glipizide Does Not Inhibit Ischemic Preconditioning in Anesthetized Rabbits

Carolyn B Levy, W. Soeller, J. Treadway, 2005, Cardiovascular Drugs and Therapy.

Aldose reductase inhibition alone or combined with an adenosine A(3) agonist reduces ischemic myocardial injury.

P. Oates, D. Knight, A. Smith, 2000, American journal of physiology. Heart and circulatory physiology.

Selective adenosine A3 receptor stimulation reduces ischemic myocardial injury in the rabbit heart.

R. J. Hill, D. Knight, S. Kennedy, 1997, Cardiovascular research.

Evidence for a role for both the adenosine A1 and A3 receptors in protection of isolated human atrial muscle against simulated ischaemia.

R. J. Hill, D. Knight, D. Yellon, 1997, Cardiovascular research.

Parasympathetic Coronary Vasoconstriction Induced by Nicotine in Conscious Calves

S. Vatner, D. Knight, M. Young, 1988, Circulation research.

Superoxide dismutase reduces reperfusion arrhythmias but fails to salvage regional function or myocardium at risk in conscious dogs.

J. Fallon, S. Vatner, M. Cohen, 1989, Circulation.

Effects of Calcium Channel Blocker on Responses of Blood Flow, Function, Arrhythmias, and Extent of Infarction Following Reperfusion in Conscious Baboons

J. Fallon, S. Vatner, T. Patrick, 1988, Circulation research.

Effects of renin inhibition compared to angiotensin converting enzyme inhibition in conscious dogs with pacing-induced heart failure.

R. Shannon, M. Mathier, D. Knight, 1997, Cardiovascular research.

NO modulates myocardial O2consumption in the nonhuman primate: an additional mechanism of action of amlodipine.

C. Doe, T. Hintze, D. Flynn, 1999, American journal of physiology. Heart and circulatory physiology.

Vasoconstrictor action of angiotensin I-convertase and the synthetic substrate (Pro11,D-Ala12)-angiotensin I.

K. W. Hoover, M. Mangiapane, D. Knight, 1994, Hypertension.

Subtypes of β‐Adrenergic Receptors in Bovine Coronary Arteries

S. Vatner, D. Vatner, D. Knight, 1986 .

Cloning, expression and pharmacological characterization of rabbit adenosine A1 and A3 receptors.

R. J. Hill, D. Knight, J. Oleynek, 1997, The Journal of pharmacology and experimental therapeutics.

Progressive change in collateral blood flow after coronary occlusion in conscious dogs.

S. Vatner, Y. Shen, D. Knight, 1989, American Journal of Physiology.

Novel variants in human and monkey CETP.

D. Knight, L. Wood, Maruja Lira, 2005, Biochimica et biophysica acta.

One hour of myocardial ischemia in conscious dogs increases beta-adrenergic receptors, but decreases adenylate cyclase activity.

S. Vatner, D. Vatner, Y. Shen, 1988, Journal of molecular and cellular cardiology.

Novel N6-substituted adenosine 5'-N-methyluronamides with high selectivity for human adenosine A3 receptors reduce ischemic myocardial injury.

R. J. Hill, D. Flynn, D. Knight, 2003, American journal of physiology. Heart and circulatory physiology.

NO modulates myocardial O2consumption in the nonhuman primate: an additional mechanism of action of amlodipine.

C. Doe, T. Hintze, D. Flynn, 1999, American journal of physiology. Heart and circulatory physiology.

Acetylcholine-induced coronary vasoconstriction and vasodilation in tranquilized baboons.

S. Vatner, Y. Shen, D. Knight, 1991, Circulation research.

One Hour of Myocardial Ischemia Decreases the Activity of the Stimulatory Guanine-Nucleotide Regulatory Protein Gs

S. Vatner, D. Vatner, D. Knight, 1989, Circulation research.

Alteration of ischemic cardiac function in normal heart by daily exercise.

H. L. Stone, D. Knight, 1983, Journal of applied physiology: respiratory, environmental and exercise physiology.

Autonomic control of large coronary arteries and resistance vessels.

S. Vatner, D. Knight, M. Young, 1987, Progress in cardiovascular diseases.

Calcium channel blockers induce preferential coronary vasodilation by an alpha 1-mechanism.

S. Vatner, D. Knight, 1987, American Journal of Physiology.

Alpha-adrenergic vasoconstriction and receptor subtypes in large coronary arteries of calves.

S. Vatner, R. Graham, D. Vatner, 1988, The American journal of physiology.

Zoniporide: a potent and selective inhibitor of the human sodium-hydrogen exchanger isoform 1 (NHE-1).

A. Fossa, D. Knight, A. Guzman-Perez, 2006, Cardiovascular drug reviews.

Effects of selective cardiac denervation on collateral blood flow after coronary artery occlusion in conscious dogs.

S. Vatner, Y. Shen, D. Knight, 1990, Basic research in cardiology.

Tachycardia-induced primate model of heart failure in cardiovascular drug discovery.

C. Doe, D. Flynn, E. Wolfgang, 2000, Journal of pharmacological and toxicological methods.

Cloning , Expression and Pharmacological Characterization of Rabbit Adenosine A 1 and A 3 Receptors

R. J. Hill, D. Knight, J. Oleynek, 1997 .

Relative importance of adenosine A1 and A3 receptors in mediating physiological or pharmacological protection from ischemic myocardial injury in the rabbit heart.

R. J. Hill, D. Knight, J. Oleynek, 1998, Journal of molecular and cellular cardiology.

Beta-receptors and adenylate cyclase: comparison of nonischemic, ischemic, and postmortem tissue.

S. Vatner, D. Vatner, D. Knight, 1990, The American journal of physiology.

Effects of a calcium channel blocker on cardiac output distribution in conscious hypertensive dogs.

S. Vatner, D. Knight, D. A. Kirby, 1985, Hypertension.

Discovery of zoniporide: a potent and selective sodium-hydrogen exchanger type 1 (NHE-1) inhibitor with high aqueous solubility.

R. J. Hill, D. Knight, A. Guzman-Perez, 2001, Bioorganic & medicinal chemistry letters.

Effects of Renin Inhibition in the Conscious Primate Macaca fascicularis

S. Vatner, E. Haber, L. Hartley, 1989, Hypertension.

Cardiovascular effects of CP-96,345, a non-peptide blocker of tachykinin NK1 receptors.

E. Wolfgang, D. Knight, J. W. Constantine, 1994, European journal of pharmacology.

Effects of left circumflex coronary flow transducer implantation on posterior wall innervation.

W. C. Randall, S. Vatner, D. Knight, 1987, The American journal of physiology.

Zoniporide: a potent and highly selective inhibitor of human Na(+)/H(+) exchanger-1.

R. J. Hill, D. Knight, Janice A. Brown, 2002, European journal of pharmacology.

Relative roles of cardiac receptors and arterial baroreceptors during hemorrhage in conscious dogs.

S. Vatner, Y. Shen, D. Knight, 1990, Circulation research.

CCR2 receptor blockade alters blood monocyte subpopulations but does not affect atherosclerotic lesions in apoE(-/-) mice.

A. Kalgutkar, D. Knight, R. Gladue, 2010, Atherosclerosis.

Mechanistic studies of blood pressure in rats treated with a series of cholesteryl ester transfer protein inhibitors

W. Loging, S. Winter, J. Keiser, 2009 .

Torcetrapib induces aldosterone and cortisol production by an intracellular calcium-mediated mechanism independently of cholesteryl ester transfer protein inhibition.

W. Loging, J. Keiser, X. Hu, 2009, Endocrinology.

Impact of delayed reperfusion of myocardial hibernation on myocardial ultrastructure and function and their recoveries after reperfusion in a pig model of myocardial hibernation.

D. Waters, J. Fallon, L. Gillam, 2000, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.

Increased myocardial infarct size because of reduced coronary collateral blood flow in beagles.

S. Vatner, M. Cohen, Y. Shen, 1989, The American journal of physiology.

Subtypes of beta-adrenergic receptors in bovine coronary arteries.

S. Vatner, D. Vatner, D. Knight, 1986, Circulation research.

Effects of age on noninvasive assessments of vascular function in nonhuman primates: implications for translational drug discovery

D. Knight, D. Beebe, S. Sokolowski, 2013, Journal of Translational Medicine.

Effects of CP-532,623 and Torcetrapib, Cholesteryl Ester Transfer Protein Inhibitors, on Arterial Blood Pressure

S. Winter, J. Keiser, E. Blasi, 2009, Journal of cardiovascular pharmacology.

Cardioprotective effects of ingliforib, a novel glycogen phosphorylase inhibitor.

Carolyn B Levy, R. McPherson, J. Treadway, 2004, American journal of physiology. Heart and circulatory physiology.

Norepinephrine-induced beta 1-adrenergic peripheral vasodilation in conscious dogs.

S. Vatner, T. Hintze, D. Knight, 1985, The American journal of physiology.

Effects of altered site of electrical activation on myocardial performance during inotropic stimulation.

S. Vatner, G. Heyndrickx, D. Knight, 1985, Circulation.

Responses to coronary artery occlusion in conscious dogs with selective cardiac denervation.

W. C. Randall, S. Vatner, Y. Shen, 1988, The American journal of physiology.

Effect of post-mortem time on. beta. -adrenergic receptor binding and adenylate cyclase activity

D. Vatner, D. Knight, C. Homcy, 1986 .

Beta 1-adrenergic regulation of large coronary arteries in conscious dogs.

S. Vatner, T. Hintze, D. Knight, 1984, Bibliotheca cardiologica.

The synthesis of highly potent, selective, and water-soluble agonists at the human adenosine A3 receptor.

R. J. Hill, D. Knight, J. Oleynek, 2006, Bioorganic & medicinal chemistry letters.

3'-Aminoadenosine-5'-uronamides: discovery of the first highly selective agonist at the human adenosine A3 receptor.

R. J. Hill, D. Knight, J. Oleynek, 2003, Journal of medicinal chemistry.

Editorial overview: cardioprotective drugs for myocardial ischemic injury--a therapeutic area at risk.

D. Knight, 2007, Current opinion in investigational drugs.

Effects of age on noninvasive assessments of vascular function in nonhuman primates: implications for translational drug discovery

D. Knight, D. Beebe, S. Sokolowski, 2013, Journal of Translational Medicine.