W. Chiang

发表

Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia

S. Beck, Marina Garcia Garrido, V. Sothilingam, 2015, Nature Genetics.

IRE1 directs proteasomal and lysosomal degradation of misfolded rhodopsin

W. Chiang, Jonathan H. Lin, Carissa Messah, 2012, Molecular biology of the cell.

Selective activation of ATF6 and PERK endoplasmic reticulum stress signaling pathways prevent mutant rhodopsin accumulation.

W. Chiang, Jonathan H. Lin, N. Hiramatsu, 2012, Investigative ophthalmology & visual science.

Autosomal recessive cone-rod dystrophy can be caused by mutations in the ATF6 gene

Anna Skorczyk-Werner, A. Wawrocka, Katarzyna Wicher, 2017, European Journal of Human Genetics.

Multiexon deletion alleles of ATF6 linked to achromatopsia.

Daniel L. Chao, S. Tsang, A. Moore, 2020, JCI insight.

Enzymatic and transcriptional regulation of human ecto-ATPase/E-NTPDase 2.

A. Knowles, W. Chiang, 2003, Archives of biochemistry and biophysics.

ASIP COTRAN EARLY CAREER INVESTIGATOR AWARD LECTURE Multiple Mechanisms of Unfolded Protein ResponseeInduced Cell Death

C. Sigurdson, W. Chiang, Jonathan H. Lin, 2015 .

Multiple Mechanisms of Unfolded Protein Response-Induced Cell Death

C. Sigurdson, W. Chiang, Jonathan H. Lin, 2022 .

Pathomechanisms of ATF6-Associated Cone Photoreceptor Diseases.

W. Chiang, Jonathan H. Lin, H. Kroeger, 2019, Advances in experimental medicine and biology.

Achromatopsia mutations target sequential steps of ATF6 activation

Anna Skorczyk-Werner, M. Krawczyński, R. Kaufman, 2016, Proceedings of the National Academy of Sciences.

Transmembrane domain interactions affect the stability of the extracellular domain of the human NTPDase 2.

A. Knowles, W. Chiang, 2008, Archives of biochemistry and biophysics.

Network biology analysis of P23H rhodopsin interactome identifies protein and mRNA quality control mechanisms

W. Chiang, Jonathan H. Lin, J. Coppinger, 2022, Scientific Reports.

ATF6 is essential for human cone photoreceptor development

J. Kelly, E. Powers, M. Michaelides, 2020, Proceedings of the National Academy of Sciences.

Proteostasis Modulation Prevents Photoreceptor Pathology in Retinal Organoids

J. Kelly, E. Powers, M. Michaelides, 2020 .

Endoplasmic reticulum stress in human photoreceptor diseases

S. Kohl, W. Chiang, Jonathan H. Lin, 2016, Brain Research.

The unfolded protein response regulator ATF6 promotes mesodermal differentiation

S. Tsang, J. Kelly, E. Powers, 2018, Science Signaling.

Induction of endoplasmic reticulum stress genes, BiP and chop, in genetic and environmental models of retinal degeneration.

M. Lavail, Victory Joseph, W. Chiang, 2012, Investigative ophthalmology & visual science.

De Novo Prion Aggregates Trigger Autophagy in Skeletal Muscle

E. Masliah, C. Sigurdson, P. Liberski, 2013, Journal of Virology.

ER stress and unfolded protein response in ocular health and disease

W. Chiang, Jonathan H. Lin, H. Kroeger, 2018, The FEBS journal.

Endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins and mutant P23H rhodopsin in photoreceptor cells.

W. Chiang, Jonathan H. Lin, H. Kroeger, 2012, Advances in experimental medicine and biology.

Robust Endoplasmic Reticulum-Associated Degradation of Rhodopsin Precedes Retinal Degeneration

M. Lavail, K. Palczewski, Sanae Sakami, 2015, Molecular Neurobiology.

Ablation of Chop Transiently Enhances Photoreceptor Survival but Does Not Prevent Retinal Degeneration in Transgenic Mice Expressing Human P23H Rhodopsin.

M. Lavail, A. Lewin, Victory Joseph, 2016, Advances in experimental medicine and biology.

In Vivo Visualization of Endoplasmic Reticulum Stress in the Retina Using the ERAI Reporter Mouse.

M. Lavail, T. Iwawaki, W. Chiang, 2015, Investigative ophthalmology & visual science.

ATF6 is essential for human cone photoreceptor development

E. Powers, M. Michaelides, J. Carroll, 2021, Proceedings of the National Academy of Sciences.

Multiple Mechanisms of Unfolded Protein Response-Induced Cell Death.

C. Sigurdson, W. Chiang, Jonathan H. Lin, 2015, The American journal of pathology.

In Vivo Visualization of Endoplasmic Reticulum Stress in the Retina Using the ERAI Reporter Mouse.

M. Lavail, T. Iwawaki, W. Chiang, 2015, Investigative ophthalmology & visual science.

Selective activation of ATF6 and PERK endoplasmic reticulum stress signaling pathways prevent mutant rhodopsin accumulation.

W. Chiang, Jonathan H. Lin, N. Hiramatsu, 2012, Investigative ophthalmology & visual science.