A. Canals

发表

A Novel Family of Soluble Minimal Scaffolds Provides Structural Insight into the Catalytic Domains of Integral Membrane Metallopeptidases*

M. Martí-Renom, C. López-Otín, Francisco Martínez-Jiménez, 2013, The Journal of Biological Chemistry.

tRNA deamination by ADAT requires substrate-specific recognition mechanisms and can be inhibited by tRFs

L. Ribas de Pouplana, A. Canals, M. Coll, 2019, RNA.

Cloning, expression, purification and crystallization of the Rho transcription termination factor from Thermotoga maritima.

A. Canals, M. Coll, 2009, Protein expression and purification.

DNA-binding drugs caught in action: the latest 3D pictures of drug-DNA complexes.

A. Canals, M. Coll, D. R. Boer, 2009, Dalton transactions.

The structure of a transcription activation subcomplex reveals how σ70 is recruited to PhoB promoters

M. Solà, J. Bernués, A. Canals, 2011, The EMBO journal.

PhoB transcriptional activator binds hierarchically to pho box promoters

A. Canals, M. Coll, Alexandre G. Blanco, 2012, Biological chemistry.

σ70 and PhoB activator

A. Canals, M. Coll, Alexandre G. Blanco, 2012, Transcription.

The structure of the complex between &agr;‐tubulin, TBCE and TBCB reveals a tubulin dimer dissociation mechanism

R. Janowski, J. Valpuesta, J. Martín-Benito, 2015, Journal of Cell Science.

The anticancer agent ellipticine unwinds DNA by intercalative binding in an orientation parallel to base pairs.

A. Canals, M. Coll, Miquel Coll, 2005, Acta crystallographica. Section D, Biological crystallography.

Site‐directed mutagenesis of mouse glutathione transferase P1‐1 unlocks masked cooperativity, introduces a novel mechanism for ‘ping pong’ kinetic behaviour, and provides further structural evidence for participation of a water molecule in proton abstraction from glutathione

A. Canals, M. Coll, Miquel Coll, 2011, The FEBS journal.

The structure of an engineered domain-swapped ribonuclease dimer and its implications for the evolution of proteins toward oligomerization.

A. Benito, J. Pous, M. Vilanova, 2001, Structure.

Three-dimensional structure of a human pancreatic ribonuclease variant, a step forward in the design of cytotoxic ribonucleases.

A. Benito, J. Pous, M. Vilanova, 2000, Journal of molecular biology.

Production of engineered human pancreatic ribonucleases, solving expression and purification problems, and enhancing thermostability.

E. Mombelli, A. Benito, M. Vilanova, 1999, Protein expression and purification.

Structure of xylanase Xys1Δ from Streptomyces halstedii

F. Gomis-Rüth, M. Díaz, R. Santamaría, 2003 .

Purification of engineered human pancreatic ribonuclease.

A. Benito, M. Nogués, M. Vilanova, 2001, Methods in enzymology.

The structure of RNA-free Rho termination factor indicates a dynamic mechanism of transcript capture.

I. Usón, A. Canals, M. Coll, 2010, Journal of molecular biology.