Kyounghyun Kim

发表

HOTAIR IS A NEGATIVE PROGNOSTIC FACTOR AND EXHIBITS PRO-ONCOGENIC ACTIVITY IN PANCREATIC CANCER

S. Safe, I. Jutooru, R. Burghardt, 2012, Oncogene.

Betulinic Acid Targets YY1 and ErbB2 through Cannabinoid Receptor-Dependent Disruption of MicroRNA-27a:ZBTB10 in Breast Cancer

S. Safe, I. Jutooru, P. Lei, 2012, Molecular Cancer Therapeutics.

DRIP150 Coactivation of Estrogen Receptor α in ZR-75 Breast Cancer Cells Is Independent of LXXLL Motifs*

J. Sacchettini, S. Safe, Jeongeun Lee, 2005, Journal of Biological Chemistry.

In vivo profiling of estrogen receptor/specificity protein-dependent transactivation.

S. Safe, Fei Wu, Kyounghyun Kim, 2008, Endocrinology.

ROLE OF TET2 IN LUMINAL DIFFERENTIATION AND HORMONE THERAPY RESPONSE IN BREAST CANCER

S. Lelièvre, Kyounghyun Kim, Chun-Ju Chang, 2019 .

Curcumin and synthetic analogs induce reactive oxygen species and decreases specificity protein (Sp) transcription factors by targeting microRNAs

S. Safe, Kyounghyun Kim, R. Rosengren, 2012, BMC Cancer.

The Transcriptional Repressor

S. Safe, I. Jutooru, Wonseok Yang, 2014 .

The Transcriptional Repressor ZBTB4 Regulates EZH2 Through a MicroRNA-ZBTB4-Specificity Protein Signaling Axis12

S. Safe, I. Jutooru, Wonseok Yang, 2014, Neoplasia.

Aryl Hydrocarbon Receptor (AHR) Agonists Induce MicroRNA-335 Expression And Inhibit Lung Metastasis of Estrogen Receptor Negative Breast Cancer Cells

S. Safe, Xinyi Liu, Kyounghyun Kim, 2011 .

Aryl Hydrocarbon Receptor Agonists Induce MicroRNA-335 Expressionand Inhibit LungMetastasis of EstrogenReceptor Negative Breast Cancer Cells

S. Safe, Xinyi Liu, Kyounghyun Kim, 2011 .

3-Methylcholanthrene and other aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha.

S. Safe, R. Finnell, E. Ariazi, 2006, Cancer research.

Inhibition of rhabdomyosarcoma cell and tumor growth by targeting specificity protein (Sp) transcription factors

Stephen Safe, S. Safe, Satya S. Pathi, 2013, International journal of cancer.

Domains of Estrogen Receptor α (ERα) Required for ERα/Sp1-Mediated Activation of GC-Rich Promoters by Estrogens and Antiestrogens in Breast Cancer Cells

Brad Saville, Stephen Safe, S. Safe, 2003 .

Activation of nuclear TR3 (NR4A1) by a diindolylmethane analog induces apoptosis and proapoptotic genes in pancreatic cancer cells and tumors.

S. Safe, Sung-Dae Cho, K. Yoon, 2011, Carcinogenesis.

References and Notes Supporting Online Material Materials and Methods Som Text Figs. S1 to S6 Tables S1 to S4 Gender Disparity in Liver Cancer Due to Sex Differences in Myd88-dependent Il-6 Production

Michael Karin, Willscott E. Naugler, C. Meiklejohn, 2022 .

Inactivation of the orphan nuclear receptor TR3/Nur77 inhibits pancreatic cancer cell and tumor growth.

Huamin Wang, M. Abdelrahim, K. Yoon, 2010, Cancer research.

Cancer esearch apeutics , Targets , and Chemical Biology tivation of the Orphan Nuclear Receptor TR 3 / Nur 77 R bits Pancreatic Cancer Cell and Tumor Growth

Huamin Wang, M. Abdelrahim, K. Yoon, 2010 .

Molecular mechanism of inhibitory aryl hydrocarbon receptor-estrogen receptor/Sp1 cross talk in breast cancer cells.

R. Burghardt, Kyounghyun Kim, Shaheen Khan, 2006, Molecular endocrinology.

Nuclear receptor-mediated transactivation through interaction with Sp proteins.

S. Safe, Kyounghyun Kim, 2004, Progress in nucleic acid research and molecular biology.

Domain analysis for estrogen receptor/Sp1-mediated transactivation and detection of estrogen receptor/Sp1 protein interactions in living cells

Kyounghyun Kim, 2005 .

Reconstruction of nuclear receptor network reveals that NR2E3 is a novel upstream regulator of ESR1 in breast cancer

G. Mills, Yiling Lu, Ju-Seog Lee, 2012, EMBO molecular medicine.

Non-classical genomic estrogen receptor (ER)/specificity protein and ER/activating protein-1 signaling pathways.

Stephen Safe, S. Safe, Kyounghyun Kim, 2008, Journal of molecular endocrinology.

Induction of the Transcriptional Repressor ZBTB4 in Prostate Cancer Cells by Drug-Induced Targeting of MicroRNA-17-92/106b-25 Clusters

Ju-Seog Lee, S. Safe, Satya S. Pathi, 2012, Molecular Cancer Therapeutics.

Therapeutic Discovery Induction of the Transcriptional Repressor ZBTB 4 in Prostate CancerCells byDrug-InducedTargeting ofMicroRNA-1792 / 106 b-25 Clusters

Ju-Seog Lee, S. Safe, Satya S. Pathi, 2012 .

Gene Expression Signature Analysis Identifies Vorinostat as a Candidate Therapy for Gastric Cancer

Jae Yong Cho, Gordon B. Mills, Woonyoung Choi, 2011, PloS one.

Aryl Hydrocarbon Receptor Agonists Induce MicroRNA-335 Expression and Inhibit Lung Metastasis of Estrogen Receptor Negative Breast Cancer Cells

S. Safe, B. Amendt, Xinyi Liu, 2011, Molecular Cancer Therapeutics.

Specificity protein (Sp) transcription factors Sp1, Sp3 and Sp4 are non-oncogene addiction genes in cancer cells

S. Safe, Yating Cheng, Kyounghyun Kim, 2016, Oncotarget.

FOXM1 mediates Dox resistance in breast cancer by enhancing DNA repair.

Ju-Seog Lee, G. Peng, A. Sood, 2019, Carcinogenesis.

Abstract 2962: FOXM1 mediates Dox resistance in breast cancer by enhancing DNA repair

Ju-Seog Lee, G. Peng, A. Sood, 2012 .

MDM2 regulates estrogen receptor α and estrogen responsiveness in breast cancer cells.

S. Safe, R. Burghardt, Xinyi Liu, 2010, Journal of molecular endocrinology.

MDM 2 regulates estrogen rece ptor a and estrogen responsiveness in breast cancer cells

S. Safe, R. Burghardt, Xinyi Liu, 2011 .

Analysis of estrogen receptor alpha-Sp1 interactions in breast cancer cells by fluorescence resonance energy transfer.

Rola Barhoumi, Stephen Safe, S. Safe, 2005, Molecular endocrinology.

MicroRNA-26b Represses Colon Cancer Cell Proliferation by Inhibiting Lymphoid Enhancer Factor 1 Expression

S. Safe, M. Goodheart, Zichao Zhang, 2013, Molecular Cancer Therapeutics.

Curcumin and synthetic analogs induce reactive oxygen species and decreases specificity protein (Sp) transcription factors by targeting microRNAs

S. Safe, Kyounghyun Kim, R. Rosengren, 2012, BMC Cancer.

IDENTIFICATION OF ONCOGENIC MicroRNA-17-92/ZBTB4/SPECIFICITY PROTEIN AXIS IN BREAST CANCER

Stephen Safe, P. Defossez, Ju-Seog Lee, 2011, Oncogene.

MicroRNA-27a Indirectly Regulates Estrogen Receptor {alpha} Expression and Hormone Responsiveness in MCF-7 Breast Cancer Cells.

S. Safe, S. Mertens-Talcott, Kyounghyun Kim, 2010, Endocrinology.

Specificity protein (Sp) transcription factors and metformin regulate expression of the long non-coding RNA HULC

J. Corton, S. Safe, V. Nair, 2015, Oncotarget.

Mechanism of Action of Phenethylisothiocyanate and Other Reactive Oxygen Species-Inducing Anticancer Agents

S. Safe, Satya S. Pathi, I. Jutooru, 2014, Molecular and Cellular Biology.

The androgen receptor inhibits transcription of GPER1 by preventing Sp1 and Sp3 from binding to the promoters in prostate cancer cells

S. Ho, Y. Leung, Kyounghyun Kim, 2021, Oncotarget.

Genetic Properties Influencing the Evolvability of Gene Expression

Michael Karin, Willscott E. Naugler, M. Karin, 2007 .

Deregulation of NR2E3, an orphan nuclear receptor, by benzo(a)pyrene-induced oxidative stress is associated with histone modification status change of the estrogen receptor gene promoter.

D. Choubey, Kyounghyun Kim, Abby L. Johnson, 2015, Toxicology letters.

NR4A orphan receptors and cancer

S. Safe, Kyounghyun Kim, Xi Li, 2011 .

Regulation of a long noncoding RNA MALAT1 by aryl hydrocarbon receptor in pancreatic cancer cells and tissues.

A. Puga, Ji-Eun Lee, Kyounghyun Kim, 2020, Biochemical and biophysical research communications.

Loss of NR2E3 represses AHR by LSD1 reprogramming, is associated with poor prognosis in liver cancer

A. Puga, S. Ho, Y. Leung, 2017, Scientific Reports.

Therapeutic Discovery Aryl Hydrocarbon Receptor Agonists Induce MicroRNA-335 Expressionand Inhibit LungMetastasis of EstrogenReceptor Negative Breast Cancer Cells

S. Safe, B. Amendt, Xinyi Liu, 2011 .

NR2E3 is a key component in p53 activation by regulating a long noncoding RNA DINO in acute liver injuries

S. Ho, Y. Leung, Kyounghyun Kim, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The Nuclear Receptor TR3 Regulates mTORC1 Signaling in Lung Cancer Cells Expressing Wild-type p53

S. Safe, Kyounghyun Kim, U. Jin, 2011, Oncogene.

Domains of estrogen receptor alpha (ERalpha) required for ERalpha/Sp1-mediated activation of GC-rich promoters by estrogens and antiestrogens in breast cancer cells.

Brad Saville, Stephen Safe, S. Safe, 2003, Molecular endocrinology.

Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols.

G. Yang, C. S. Yang, J. Liao, 1998, Carcinogenesis.

Loss of NR2E3 represses AHR by LSD1 reprogramming, is associated with poor prognosis in liver cancer

A. Puga, S. Ho, Y. Leung, 2017, Scientific Reports.

Specificity protein (Sp) transcription factors Sp1, Sp3 and Sp4 are non-oncogene addiction genes in cancer cells

S. Safe, Yating Cheng, Kyounghyun Kim, 2016, OncoTarget.

Transcriptional activation of heat shock protein 27 gene expression by 17beta-estradiol and modulation by antiestrogens and aryl hydrocarbon receptor agonists.

S. Safe, E. Castro-Rivera, K. Kim, 2001, Journal of molecular endocrinology.

Inactivation of the orphan nuclear receptor TR3/Nur77 inhibits pancreatic cancer cell and tumor growth.

Huamin Wang, M. Abdelrahim, K. Yoon, 2010, Cancer research.

Specificity protein (Sp) transcription factors and metformin regulate expression of the long non-coding RNA HULC

J. Corton, V. Nair, Yating Cheng, 2015, Oncotarget.

Aryl Hydrocarbon Receptor Agonists Induce MicroRNA-335 Expression and Inhibit Lung Metastasis of Estrogen Receptor Negative Breast Cancer Cells

S. Safe, B. Amendt, Xinyi Liu, 2011, Molecular Cancer Therapeutics.