Ihab Younis

发表

U1 snRNP protects pre-mRNAs from premature cleavage and polyadenylation

Larry N. Singh, G. Dreyfuss, D. Kaida, 2010, Nature.

U1 snRNP Determines mRNA Length and Regulates Isoform Expression

Larry N. Singh, G. Dreyfuss, A. Pinto, 2012, Cell.

U1 snRNP regulates cancer cell migration and invasion in vitro

Chao Di, Jung-Min Oh, Lili Wan, 2020, Nature Communications.

U1 snRNP regulates cancer cell migration and invasion

G. Dreyfuss, A. Pinto, Ihab Younis, 2019, bioRxiv.

U1 snRNP telescripting regulates a size–function-stratified human genome

G. Dreyfuss, A. Pinto, Ihab Younis, 2017, Nature Structural & Molecular Biology.

Aberrant development of pancreatic beta cells derived from human iPSCs with FOXA2 deficiency

K. Hussain, Ihab Younis, A. Elsayed, 2021, Cell death & disease.

The human T-cell leukemia virus Rex protein.

P. Green, Ihab Younis, 2005, Frontiers in bioscience : a journal and virtual library.

iPSCs derived from insulin resistant offspring of type 2 diabetic patients show increased oxidative stress and lactate secretion

A. Abou-Samra, Ihab Younis, A. Elsayed, 2022, Stem cell research & therapy.

Human T-Cell Leukemia Virus Type 2 Rex Carboxy Terminus Is an Inhibitory/Stability Domain That Regulates Rex Functional Activity and Viral Replication

M. Lairmore, P. Green, M. Kesic, 2009, Journal of Virology.

PDX1−/NKX6.1+ progenitors derived from human pluripotent stem cells as a novel source of insulin‐secreting cells

Ihab Younis, E. Abdelalim, Bushra Memon, 2020, Diabetes/metabolism research and reviews.

Inhibiting PARP1 Splicing along with Inducing DNA Damage as Potential Breast Cancer Therapy

Ihab Younis, Reem K M E Alsayed, 2021 .

Repression of Human T-Cell Leukemia Virus Type 1 and Type 2 Replication by a Viral mRNA-Encoded Posttranscriptional Regulator

M. Dundr, M. Lairmore, P. Green, 2004, Journal of Virology.

Functional Domain Structure of Human T-Cell Leukemia Virus Type 2 Rex

P. Green, Ihab Younis, D. D'Agostino, 2003, Journal of Virology.

Human T-cell leukemia virus type 2 post-transcriptional control protein p28 is required for viral infectivity and persistence in vivo

M. Lairmore, P. Green, M. Kesic, 2008, Retrovirology.

Human T-Cell Leukemia Virus Open Reading Frame II Encodes a Posttranscriptional Repressor That Is Recruited at the Level of Transcription

P. Green, K. Boris-Lawrie, Ihab Younis, 2006, Journal of Virology.

Minor introns are embedded molecular switches regulated by highly unstable U6atac snRNA

G. Dreyfuss, Zhi Wei, K. Dittmar, 2013, eLife.

A challenging ‘bag of worms’: adolescent varicocele

Ihab Younis, Ahmed H. Hamed, 2015 .

Enhancement of infectivity and persistence in vivo by HBZ, a natural antisense coded protein of HTLV-1.

Joshua Arnold, M. Lairmore, P. Green, 2006, Blood.

The Cancer Spliceome: Reprograming of Alternative Splicing in Cancer

Ihab Younis, Ettaib El Marabti, 2018, Front. Mol. Biosci..

SMN Deficiency Causes Tissue-Specific Perturbations in the Repertoire of snRNAs and Widespread Defects in Splicing

Lili Wan, G. Dreyfuss, K. Dittmar, 2008, Cell.

Synthesis of full-gene-length transcripts from the majority of pro- tein-coding genes is not the default process in metazoans; rather, it depends on the suppression of PCPA from cryptic polyadenyla-

G. Dreyfuss, A. Pinto, Ihab Younis, 2017 .

A U1 snRNP-Specific Assembly Pathway Reveals the SMN Complex as a Versatile RNP Exchange

G. Dreyfuss, Pilong Li, Ihab Younis, 2016, Nature Structural &Molecular Biology.

A U 1 snRNP – specific assembly pathway reveals the SMN complex as a versatile hub for RNP exchange

G. Dreyfuss, Pilong Li, Ihab Younis, 2016 .

Rapid-Response Splicing Reporter Screens Identify Differential Regulators of Constitutive and Alternative Splicing

G. Dreyfuss, K. Dittmar, D. Kaida, 2010, Molecular and Cellular Biology.

Keratinocytes Derived from Patient-Specific Induced Pluripotent Stem Cells Recapitulate the Genetic Signature of Psoriasis Disease

S. Taheri, Ihab Younis, Manjula Nandakumar, 2020, Stem cells and development.

Minor Intron Splicing from Basic Science to Disease

J. Malek, Ihab Younis, Ettaib El Marabti, 2021, International journal of molecular sciences.

Scalable Generation of Mesenchymal Stem Cells and Adipocytes from Human Pluripotent Stem Cells

Ihab Younis, E. Abdelalim, Manale Karam, 2020, bioRxiv.

PYM binds the cytoplasmic exon-junction complex and ribosomes to enhance translation of spliced mRNAs

G. Dreyfuss, M. Diem, Ihab Younis, 2007, Nature Structural &Molecular Biology.

A Quantitative High-Throughput In Vitro Splicing Assay Identifies Inhibitors of Spliceosome Catalysis

G. Dreyfuss, M. Diem, Michael G. Berg, 2012, Molecular and Cellular Biology.

Rapid-Response Splicing Reporter Screens Identify Differential

G. Dreyfuss, K. Dittmar, D. Kaida, 2010 .

Human T-Cell Leukemia Virus Type 1 Expressing Nonoverlapping Tax and Rex Genes Replicates and Immortalizes Primary Human T Lymphocytes but Fails To Replicate and Persist In Vivo

P. Green, Ihab Younis, A. Phipps, 2005, Journal of Virology.

Aberrant development of pancreatic beta cells derived from human iPSCs with FOXA2 deficiency

Ihab Younis, A. Elsayed, E. Abdelalim, 2021, Cell Death & Disease.

Human T-cell leukemia virus type 2 post-transcriptional control protein p28 is required for viral infectivity and persistence in vivo

M. Lairmore, P. Green, M. Kesic, 2008, Retrovirology.