J. Deuis

发表

Transcriptomic and behavioural characterisation of a mouse model of burn pain identify the cholecystokinin 2 receptor as an analgesic target

I. Vetter, R. Lewis, Kathleen Yin, 2016, Molecular pain.

Analgesic treatment of ciguatoxin-induced cold allodynia

I. Vetter, R. Lewis, B. Namer, 2013, PAIN®.

The pharmacology of voltage-gated sodium channel activators

Irina Vetter, I. Vetter, J. Deuis, 2017, Neuropharmacology.

High-Throughput Fluorescence Assays for Ion Channels and GPCRs.

I. Vetter, S. Robinson, D. Carter, 2020, Advances in experimental medicine and biology.

Multiple sodium channel isoforms mediate the pathological effects of Pacific ciguatoxin-1

I. Vetter, R. Lewis, A. Keramidas, 2017, Scientific Reports.

Role of complement anaphylatoxin receptors in a mouse model of acute burn‐induced pain

I. Vetter, T. Woodruff, R. Lewis, 2018, Molecular immunology.

Neurotoxic and cytotoxic peptides underlie the painful stings of the tree nettle Urtica ferox

D. Craik, I. Vetter, P. Harvey, 2022, The Journal of biological chemistry.

Polygodial, a drimane sesquiterpenoid dialdehyde purified from Drimys winteri, inhibits voltage-gated sodium channels.

I. Vetter, J. Deuis, Cristian Paz, 2022, Natural product research.

Novel Neurotoxic Activity in Calliophis intestinalis Venom

I. Vetter, B. Fry, A. Nouwens, 2021, Neurotoxicity Research.

Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system

Yuehua Wu, D. Craik, I. Vetter, 2022, Nature communications.

Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a

Glenn F. King, Paul F. Alewood, Sulayman D. Dib-Hajj, 2017, Scientific Reports.

The Tarantula Venom Peptide Eo1a Binds to the Domain II S3-S4 Extracellular Loop of Voltage-Gated Sodium Channel NaV1.8 to Enhance Activation

I. Vetter, G. King, S. Robinson, 2022, Frontiers in Pharmacology.

Characterization of Synthetic Tf2 as a NaV1.3 Selective Pharmacological Probe

D. Craik, I. Vetter, T. Durek, 2020, Biomedicines.

Addition of K22 Converts Spider Venom Peptide Pme2a from an Activator to an Inhibitor of NaV1.7

I. Vetter, G. King, P. Alewood, 2020, Biomedicines.

The thermal probe test: A novel behavioral assay to quantify thermal paw withdrawal thresholds in mice

I. Vetter, J. Deuis, 2016, Temperature.

Activation of κ Opioid Receptors in Cutaneous Nerve Endings by Conorphin-1, a Novel Subtype-Selective Conopeptide, Does Not Mediate Peripheral Analgesia.

I. Vetter, R. Lewis, P. Cabot, 2015, ACS chemical neuroscience.

Modulatory features of the novel spider toxin μ-TRTX-Df 1 a isolated from the venom of the spider Davus fasciatus . Running title : Modulation of voltage-gated channels by the spider toxin Df 1 a

I. Vetter, Jennifer J. Smith, R. Lewis, 2017 .

Corrigendum: Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a

D. A. Armstrong, S. Dib-Hajj, S. Waxman, 2017, Scientific Reports.

Role of the NLRP3 inflammasome in a model of acute burn-induced pain.

K. Schroder, I. Vetter, M. Cooper, 2017, Burns : journal of the International Society for Burn Injuries.

Low potency inhibition of NaV1.7 by externally applied QX-314 via a depolarizing shift in the voltage-dependence of activation.

I. Vetter, T. Durek, D. Carter, 2022, European journal of pharmacology.

µ-Conotoxins Targeting the Human Voltage-Gated Sodium Channel Subtype NaV1.7

D. Craik, I. Vetter, C. Schroeder, 2022, Toxins.

Development of a μO-conotoxin analogue with improved lipid membrane interactions and potency for the analgesic target Na V 1.8

D. Craik, I. Vetter, S. Henriques, 2016 .

Structural and functional insights into the inhibition of human voltage-gated sodium channels by μ -conotoxin KIIIA disul ﬁ de isomers

I. Vetter, C. Schroeder, J. Deuis, 2022 .

Development of a high-throughput fluorescent no-wash sodium influx assay

I. Vetter, J. Deuis, F. Davis, 2019, PloS one.

Vincristine-induced peripheral neuropathy is driven by canonical NLRP3 activation and IL-1β release

K. Schroder, I. Vetter, J. Lévesque, 2021, The Journal of experimental medicine.

Venom-derived pain-causing toxins: insights into sensory neuron function and pain mechanisms.

I. Vetter, Vanessa Schendel, S. Robinson, 2022, Pain.

Δ-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities.

I. Vetter, M. Aguilar, M. Cooper, 2017, Angewandte Chemie.

Development of a (cid:2) O-Conotoxin Analogue with Improved Lipid Membrane Interactions and Potency for the Analgesic Sodium Channel Na V 1.8 *

D. Craik, I. Vetter, C. Schroeder, 2020 .

Venom composition and pain-causing toxins of the Australian great carpenter bee Xylocopa aruana

I. Vetter, C. Schroeder, S. Robinson, 2022, Scientific reports.

Toxins as tools: Fingerprinting neuronal pharmacology

J. Deuis, Mathilde R. Israel, Bryan Tay, 2018, Neuroscience Letters.

Analgesic Effects of GpTx-1, PF-04856264 and CNV1014802 in a Mouse Model of NaV1.7-Mediated Pain

Paul F. Alewood, Irina Vetter, Katharina Zimmermann, 2016, Toxins.

The Snake with the Scorpion’s Sting: Novel Three-Finger Toxin Sodium Channel Activators from the Venom of the Long-Glanded Blue Coral Snake (Calliophis bivirgatus)

I. Vetter, T. Bruxner, B. Fry, 2016, Toxins.

Inflammatory and neuropathic gene expression signatures of chemotherapy-induced neuropathy induced by vincristine, cisplatin and oxaliplatin in C57BL/6J mice.

I. Vetter, D. Carter, J. Deuis, 2019, The journal of pain : official journal of the American Pain Society.

Manipulation of a spider peptide toxin alters its affinity for lipid bilayers and potency and selectivity for voltage-gated sodium channel subtype 1.7

D. Craik, I. Vetter, C. Schroeder, 2020, The Journal of Biological Chemistry.

Sodium Channels and Venom Peptide Pharmacology.

I. Vetter, J. Deuis, Mathilde R. Israel, 2017, Advances in pharmacology.

Methods Used to Evaluate Pain Behaviors in Rodents

Irina Vetter, I. Vetter, L. Dvorakova, 2017, Front. Mol. Neurosci..

Burn Pain: A Systematic and Critical Review of Epidemiology, Pathophysiology, and Treatment

I. Vetter, R. Lewis, P. Cabot, 2018, Pain medicine.

NaV1.7 as a pain target - From gene to pharmacology.

I. Vetter, M. Mobli, J. Deuis, 2017, Pharmacology & therapeutics.

An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways

A. A. Romanovsky, I. Vetter, R. Lewis, 2013, PAIN®.

Enzymatic ligation of a pore blocker toxin and gating modifier toxin; creating double-knotted peptides with improved sodium channel NaV1.7 inhibition.

I. Vetter, C. Schroeder, J. Deuis, 2019, Bioconjugate chemistry.

Engineering of a Spider Peptide via Conserved Structure-Function Traits Optimizes Sodium Channel Inhibition In Vitro and Anti-Nociception In Vivo

I. Vetter, J. Deuis, F. C. Cardoso, 2021, Frontiers in Molecular Biosciences.

NaV1.6 regulates excitability of mechanosensitive sensory neurons

S. Dib-Hajj, S. Waxman, D. Craik, 2019, The Journal of physiology.

Structural and functional insights into the inhibition of human voltage-gated sodium channels by μ-conotoxin KIIIA disulfide isomers

I. Vetter, C. Schroeder, J. Deuis, 2022, The Journal of biological chemistry.

Discovery, Pharmacological Characterisation and NMR Structure of the Novel µ-Conotoxin SxIIIC, a Potent and Irreversible NaV Channel Inhibitor

I. Vetter, C. Schroeder, R. Lewis, 2020, Biomedicines.

Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species

Terry J. Smith, S. Wray, I. Vetter, 2017, Science Signaling.

A Centipede Toxin Family Defines an Ancient Class of CSαβ Defensins.

D. Craik, I. Vetter, J. Tytgat, 2019, Structure.

Development of a O-Conotoxin Analogue with Improved Lipid Membrane Interactions and Potency for the Analgesic Sodium Channel NaV1.8

D. Craik, I. Vetter, C. Schroeder, 2016 .

α-Conotoxin MrIC is a biased agonist at α7 nicotinic acetylcholine receptors.

I. Vetter, R. Lewis, N. Daly, 2015, Biochemical pharmacology.

Analgesic effects of clinically used compounds in novel mouse models of polyneuropathy induced by oxaliplatin and cisplatin.

Irina Vetter, I. Vetter, R. Lewis, 2014, Neuro-oncology.

Evaluation of Efficient Non-reducing Enzymatic and Chemical Ligation Strategies for Complex Disulfide-Rich Peptides.

D. Craik, I. Vetter, C. Schroeder, 2021, Bioconjugate chemistry.

Pharmacological activity and NMR solution structure of the leech peptide HSTX-I.

S. Dib-Hajj, S. Waxman, I. Vetter, 2020, Biochemical pharmacology.

The structure, dynamics and selectivity profile of a NaV1.7 potency-optimised huwentoxin-IV variant

I. Vetter, R. Lewis, G. King, 2017, PloS one.

Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function

Samantha J. Stehbens, S. Dib-Hajj, S. Waxman, 2023, Nature communications.

Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi

I. Vetter, C. Bladen, R. Lewis, 2017, PloS one.

Modulatory features of the novel spider toxin μ‐TRTX‐Df1a isolated from the venom of the spider Davus fasciatus

I. Vetter, Jennifer J. Smith, R. Lewis, 2017, British journal of pharmacology.

Recombinant production, bioconjugation and membrane binding studies ofPn3a, a selective NaV1.7 inhibitor.

I. Vetter, M. Mobli, J. Deuis, 2020, Biochemical pharmacology.

Neurotoxic peptides from the venom of the giant Australian stinging tree

D. Craik, D. Andersson, I. Vetter, 2020, Science Advances.

Assessment of the TRPM8 inhibitor AMTB in breast cancer cells and its identification as an inhibitor of voltage gated sodium channels

I. Vetter, P. Kenny, A. A. Peters, 2018, Life sciences.

Changes in Potency and Subtype Selectivity of Bivalent NaV Toxins are Knot-Specific.

I. Vetter, C. Schroeder, R. Payne, 2023, Bioconjugate chemistry.

Using toxins to elucidate the role of voltage-gated sodium channels in pain

J. Deuis, 2016 .

Structural Conformation and Activity of Spider-Derived Inhibitory Cystine Knot Peptide Pn3a Are Modulated by pH

I. Vetter, C. Schroeder, M. Mobli, 2023, ACS omega.

Anti-allodynic effects of the selective NaV1.7 inhibitor Pn3a in a mouse model of acute post-surgical pain: evidence for analgesic synergy with opioids and baclofen.

I. Vetter, O. Cheneval, C. Schroeder, 2019, Pain.

Mapping the Molecular Surface of the Analgesic NaV1.7-Selective Peptide Pn3a Reveals Residues Essential for Membrane and Channel Interactions.

I. Vetter, Q. Kaas, C. Schroeder, 2020, ACS pharmacology & translational science.

Venom chemistry underlying the painful stings of velvet ants (Hymenoptera: Mutillidae)

I. Vetter, G. King, S. Robinson, 2021, Cellular and Molecular Life Sciences.

Identification and Characterization of ProTx-III [μ-TRTX-Tp1a], a New Voltage-Gated Sodium Channel Inhibitor from Venom of the Tarantula Thrixopelma pruriens

I. Vetter, K. Rosengren, P. Alewood, 2015, Molecular Pharmacology.

The ‘dispanins’ and related proteins in physiology and neurological disease

J. Deuis, Tabea Klasfauseweh, Irina Vetter, 2024, Trends in Neurosciences.

Ant venoms contain vertebrate-selective pain-causing sodium channel toxins

I. Vetter, Nina Brinkwirth, C. Schroeder, 2023, Nature communications.

Pmu1a, a novel spider toxin with dual inhibitory activity at pain targets hNaV1.7 and hCaV3 voltage‐gated channels

I. Vetter, C. Schroeder, N. Daly, 2023, The FEBS journal.