J. Graw

发表

Meis1 coordinates a network of genes implicated in eye development and microphthalmia

Leonardo Beccari, P. Bovolenta, F. Casares, 2015, Development.

11 Hemophilia A Patients without Mutations in the Factor VIII Encoding Gene

N. Klopp, J. Oldenburg, J. Graw, 2002, Thrombosis and Haemostasis.

Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans

H. Höfler, N. Pellegata, L. Quintanilla‐Martinez, 2006, Proceedings of the National Academy of Sciences.

A Humanized Version of Foxp2 Affects Cortico-Basal Ganglia Circuits in Mice

Johannes Schwarz, Julia Fischer, Valérie Gailus-Durner, 2009, Cell.

Characterization of ex vivo cultured neuronal- and glial- like cells from human idiopathic epiretinal membranes

G. Petrovski, M. Hawlina, J. Graw, 2014, BMC Ophthalmology.

Ionizing radiation induced cataracts: Recent biological and mechanistic developments and perspectives for future research.

M. Kadhim, E. Ainsbury, N. Hamada, 2016, Mutation research.

Systemic first-line phenotyping.

H. Fuchs, D. Busch, E. Wolf, 2009, Methods in molecular biology.

The German Mouse Clinic: a platform for systemic phenotype analysis of mouse models.

H. Fuchs, D. Busch, K. Schughart, 2009, Current pharmaceutical biotechnology.

Lifetime study in mice after acute low-dose ionizing radiation: a multifactorial study with special focus on cataract risk

Michael Rosemann, Christoph Hoeschen, Wolfgang Wurst, 2018, Radiation and Environmental Biophysics.

Ionising radiation causes vision impairment in neonatal B6C3F1 mice.

H. Fuchs, M. D. de Angelis, V. Gailus-Durner, 2021, Experimental eye research.

Mouse phenotyping.

H. Fuchs, D. Busch, E. Wolf, 2011, Methods.

Lens density tracking in mice by Scheimpflug imaging

M. Angelis, M. D. de Angelis, O. Puk, 2013, Mammalian Genome.

Radiation-Induced Lens Opacity and Cataractogenesis: A Lifetime Study Using Mice of Varying Genetic Backgrounds

J. Moquet, S. Pazzaglia, E. Ainsbury, 2021, Radiation Research.

Aey2, a new mutation in the betaB2-crystallin-encoding gene of the mouse.

J Graw, H. Fuchs, E. Wolf, 2001, Investigative ophthalmology & visual science.

Mouse models of cataract

J. Graw, 2009, Journal of Genetics.

A 6-bp deletion in the Crygc gene leading to a nuclear and radial cataract in the mouse.

J. Favor, J. Graw, J. Löster, 2002, Investigative ophthalmology & visual science.

Induction of gene mutations in mice: the multiple endpoint approach.

J. Favor, J. Graw, W. Pretsch, 1985, Mutation research.

Three murine cataract mutants (Cat2) are defective in different γ- crystallin genes

N. Klopp, A. Prescott, G. Vrensen, 1998 .

Mutation in the betaA3/A1-crystallin encoding gene Cryba1 causes a dominant cataract in the mouse.

H. Fuchs, E. Wolf, R. Balling, 1999, Genomics.

Aey 2 , a New Mutation in the b B 2-Crystallin – Encoding Gene of the Mouse

H. Fuchs, M. Angelis, E. Wolf, 2001 .

Characterization of Cat-2t, a radiation-induced dominant cataract mutation in mice.

K. Summer, P. M. Gopinath, W. Bors, 1990, Investigative ophthalmology & visual science.

Characterization of Scat (suture cataract), a dominant cataract mutation in mice.

P. Reitmeir, J. Graw, A. Wulff, 1989, Experimental eye research.

Genetical and biochemical studies of a dominant cataract mutant in mice.

K. Summer, J. Graw, J. Kratochvílová, 1984, Experimental eye research.

New Mutation in the Mouse Xpd/Ercc2 Gene Leads to Recessive Cataracts

Helmut Fuchs, Matthias Klaften, Ulrike Kulka, 2015, PloS one.

Nuclear breakdown during terminal differentiation of primary lens fibres in mice: a transmission electron microscopic study.

G. Vrensen, G. Vrensen, J. Graw, 1991, Experimental eye research.

α-Crystallins are involved in specific interactions with the murine γD/E/F-crystallin-encoding gene

T. Werner, J. Graw, T. Schmitt-John, 1994 .

"Sighted C3H" mice--a tool for analysing the influence of vision on mouse behaviour?

H. Fuchs, W. Wurst, M. Kallnik, 2008, Frontiers in bioscience : a journal and virtual library.

Innovations in phenotyping of mouse models in the German Mouse Clinic

H. Fuchs, D. Busch, H. Höfler, 2012, Mammalian Genome.

Crygf(Rop): the first mutation in the Crygf gene causing a unique radial lens opacity.

N. Klopp, J. Favor, J. Graw, 2002, Investigative ophthalmology & visual science.

An ENU-induced mutation in Rs1h causes disruption of retinal structure and function.

Robert W. Williams, K. Manly, Lu Lu, 2005, Molecular vision.

Variations of eye size parameters among different strains of mice

M. Angelis, J. Favor, O. Puk, 2006, Mammalian Genome.

Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia

H. Fuchs, D. Hladik, M. Irmler, 2019, Experimental eye research.

Deletion in the promoter region and altered expression of Pitx3 homeobox gene in aphakia mice.

J. Murray, J. Graw, E. Semina, 2000, Human molecular genetics.

Genetic models for cataracts

J. Graw, 2013 .

Confirmation of Single Nucleotide Mutations

J. Graw, 2012 .

A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes

J. Mason, H. Fuchs, D. Busch, 2020, Mammalian Genome.

Recessive transmission of a multiple endocrine neoplasia syndrome in the rat.

A. Fritz, M. Rosemann, H. Höfler, 2002, Cancer research.

Summary Early developmental failure of substantia nigra dopamine neurons in mice lacking the homeodomain gene Pitx 3

M. Smidt, H. Bouwmeester, J. Graw, 2004 .

Antagonistic action of Six3 and Prox1 at the gamma-crystallin promoter.

A. Prescott, J. Lengler, E. Krausz, 2001, Nucleic acids research.

Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression

W. Rottbauer, H. Fuchs, D. Busch, 2016, Nature Communications.

Standardized, systemic phenotypic analysis of Slc12a1I299F mutant mice

H. Fuchs, D. Busch, E. Wolf, 2014, Journal of Biomedical Science.

Pitx3 directly regulates Foxe3 during early lens development.

P. Carlsson, J. Beckers, J. Graw, 2013, The International journal of developmental biology.

Cancer‐retina antigens as potential paraneoplastic antigens in melanoma‐associated retinopathy

D. Schadendorf, R. Dummer, A. Bazhin, 2009, International journal of cancer.

Haemophilia A: from mutation analysis to new therapies

J. Oldenburg, M. Spannagl, R. Schwaab, 2005, Nature Reviews Genetics.

Analysis of mRNA in hemophilia A patients with undetectable mutations reveals normal splicing in the factor VIII gene

J. Oldenburg, O. el-Maarri, A. Terzić, 2005, Journal of thrombosis and haemostasis : JTH.

Permanent Neonatal Diabetes in INSC94Y Transgenic Pigs

E. Wolf, H. Blum, S. Krebs, 2013, Diabetes.

Mouse Genetics and Metabolic Mouse Phenotyping

H. Fuchs, M. Angelis, D. Busch, 2012 .

A new cat reporter gene vector designed for rapid and efficient cloning of PCR products.

E. Krausz, J. Graw, 1996, Gene.

Cat3vl and Cat3vao cataract mutations on mouse chromosome 10: phenotypic characterization, linkage studies and analysis of candidate genes

J. Graw, T. Schmitt-John, T. Immervoll, 1997, Molecular and General Genetics MGG.

Mutation in a novel connexin-like gene (Gjf1) in the mouse affects early lens development and causes a variable small-eye phenotype.

H. Fuchs, E. Wolf, M. D. de Angelis, 2008, Investigative ophthalmology & visual science.

Allelic loss of chromosomes 8 and 19 in MENX‐associated rat pheochromocytoma

N. Pellegata, S. Chevillard, M. Atkinson, 2009, International journal of cancer.

A novel human CRYGD mutation in a juvenile autosomal dominant cataract

K. Satyamoorthy, P. M. Gopinath, J. Graw, 2010, Molecular vision.

The GJA8 allele encoding CX50I247M is a rare polymorphism, not a cataract-causing mutation

N. Klopp, T. Illig, J. Graw, 2009, Molecular vision.

Relative roles of the different Pax6 domains for pancreatic alpha cell development

M. Götz, B. Göke, K. Parhofer, 2010, BMC Developmental Biology.

Long Term Optimisation of F8 Gene Mutation Screening by DHPLC

E. Seifried, H. Singer, J. Oldenburg, 2005 .

Molecular analysis of two new Steel mutations in mice shows a transversion or an insertion

J. Graw, T. Schmitt-John, W. Pretsch, 1996, Mammalian Genome.

Detection of a point mutation (A to G) in exon 5 of the murine Mgf gene defines a novel allele at the Steel locus with a weak phenotype.

J. Graw, W. Pretsch, A. Neuhäuser-Klaus, 1997, Mutation research.

Dominant cataract and recessive specific locus mutations in offspring of X-irradiated male mice.

J. Favor, J. Graw, A. Neuhäuser-Klaus, 1986, Mutation research.

Congenital cataract and macular hypoplasia in humans associated with a de novo mutation in CRYAA and compound heterozygous mutations in P

N. Klopp, T. Illig, B. Lorenz, 2006, Graefe's Archive for Clinical and Experimental Ophthalmology.

Hereditary lactate dehydrogenase A-subunit deficiency as cause of early postimplantation death of homozygotes in Mus musculus.

J. Favor, J. Graw, S. Hornhardt, 1992, Genetics.

Genotype-Phenotype Correlation in Hemophilia A

J. Oldenburg, R. Schwaab, W. Schramm, 2001 .

Are mouse lens epithelial cells more sensitive to γ-irradiation than lymphocytes?

M. Rosemann, K. Trott, M. Atkinson, 2013, Radiation and environmental biophysics.

Catalase and superoxide dismutase activities in lenses of cataractous Nop-mice.

K. Summer, W. Bors, J. Graw, 1985, Experimental eye research.

Mapping of a novel MEN-like syndrome locus to rat Chromosome 4

A. Fritz, M. Rosemann, M. Atkinson, 2004, Mammalian Genome.

Crybb2 coding for βB2-crystallin affects sensorimotor gating and hippocampal function

D. Rujescu, M. Angelis, W. Wurst, 2013, Mammalian Genome.

[Significance of mutation analysis in patients with haemophilia A].

E. Seifried, J. Oldenburg, R. Schwaab, 2003, Hamostaseologie.

[Characterization of factor VIII antibody epitopes from haemophilia A patients using cellulose bound FVIII peptide libraries].

J. Oldenburg, R. Schwaab, W. Schramm, 2003, Hamostaseologie.

Sequencing of the factor 8(F8) coding regions in 10 Turkish hemophilia A patients reveals three novel pathological mutations, and one rediagnosis of von Willebrand's disease type 2N

J. Oldenburg, O. el-Maarri, N. Akar, 2006, Haemophilia : the official journal of the World Federation of Hemophilia.

Reduced corneal thickness and enlarged anterior chamber in a novel ColVIIIa2G257D mutant mouse.

Matthias Klaften, Martin Hrabé de Angelis, Claudia Dalke, 2009, Investigative ophthalmology & visual science.

Analysis of mitochondrial DNA variations in Indian patients with congenital cataract

S. Kabekkodu, J. Graw, Mascarenhas Roshan, 2012, Molecular vision.

Characterization of a new, dominant V124E mutation in the mouse alphaA-crystallin-encoding gene.

J Graw, H. Fuchs, E. Wolf, 2001, Investigative ophthalmology & visual science.

Pleiotropic effects in Eya3 knockout mice

H. Fuchs, E. Wolf, W. Wurst, 2008, BMC Developmental Biology.

Mouse mutants for eye development.

J. Graw, 2000, Results and problems in cell differentiation.

DNase activity in murine lenses: Implications for cataractogenesis

J. Graw, A. Liebstein, 1993, Graefe's Archive for Clinical and Experimental Ophthalmology.

Clinical and experimental advances in congenital and paediatric cataracts

J. Graw, A. Churchill, 2011, Philosophical Transactions of the Royal Society B: Biological Sciences.

Genetics of crystallins: cataract and beyond.

J. Graw, 2009, Experimental eye research.

Congenital hereditary cataracts.

J. Graw, 2004, The International journal of developmental biology.

Genetic and allelic heterogeneity of Cryg mutations in eight distinct forms of dominant cataract in the mouse.

N. Klopp, P. Selby, J. Favor, 2004, Investigative ophthalmology & visual science.

The genetic and molecular basis of congenital eye defects

Jochen Graw, J. Graw, 2003, Nature Reviews Genetics.

Mouse models for microphthalmia, anophthalmia and cataracts

J. Graw, 2019, Human Genetics.

First mutation in the βA2-crystallin encoding gene is associated with small lenses and age-related cataracts.

Martin Hrabé de Angelis, Jochen Graw, M. Hrabě de Angelis, 2011, Investigative ophthalmology & visual science.

Developmental genetics in ophthalmology

J. Graw, J. Löster, 2003, Ophthalmic genetics.

Cataract mutations and lens development 1 Dedicated to Prof. Udo H. Ehling on the occasion of his 70th birthday. 1

J. Graw, 1999, Progress in Retinal and Eye Research.

Genetic aspects of embryonic eye development in vertebrates.

J. Graw, Jochen Graw, 1996, Developmental genetics.

Histological and biochemical characterization of the murine cataract mutant Nop.

T. Werner, P. Reitmeir, J. Graw, 1990, Experimental eye research.

Biochemical analysis of young rats homozygous for the cataract mutation cat.

P. M. Gopinath, W. Bors, J. Graw, 1989, Experimental eye research.

Mutation analysis in a German family identified a new cataract-causing allele in the CRYBB2 gene

N. Klopp, T. Illig, W. Engel, 2007, Molecular vision.

Identification of a novel, putative cataract-causing allele in CRYAA (G98R) in an Indian family.

N. Klopp, T. Illig, P. M. Gopinath, 2006, Molecular vision.

Veränderungen im Genom: Mutationen

J. Graw, 2020, Genetik.

Early developmental failure of substantia nigra dopamine neurons in mice lacking the homeodomain gene Pitx3

H. Bouwmeester, M. Smidt, J. Burbach, 2004, Development.

Antagonistic action of Six3 and Prox1 at the γ-crystallin promoter

A. Prescott, J. Lengler, E. Krausz, 2001 .

Genomic sequences of murine γB- and γC-crystallm-encoding genes: promoter analysis and complete evolutionary pattern of mouse, rat and human γ-crystallins

T. Werner, J. Graw, T. Schmitt-John, 1993 .

Isolation and embryonic expression of the novel mouse gene Hic1, the homologue of HIC1, a candidate gene for the Miller-Dieker syndrome.

K. Schughart, J. Adamski, T. Schmid, 1999, Human molecular genetics.

Genome-wide screening reveals the genetic basis of mammalian embryonic eye development

Jacqueline K. White, Denise G. Lanza, Jason D. Heaney, 2023, BMC Biology.

Electroretinography as a screening method for mutations causing retinal dysfunction in mice.

H. Fuchs, T. Meitinger, E. Zrenner, 2004, Investigative ophthalmology & visual science.

Mutually regulated expression of Pax6 and Six3 and its implications for the Pax6 haploinsufficient lens phenotype

P. Gruss, L. Reneker, J. Graw, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Large-Scale Phenotyping of an Accurate Genetic Mouse Model of JNCL Identifies Novel Early Pathology Outside the Central Nervous System

Edith T. Lopez, Larissa A. Haliw, H. Fuchs, 2012, PloS one.

Lack of F8 mRNA: a novel mechanism leading to hemophilia A.

T. Haaf, H. Singer, J. Oldenburg, 2006, Blood.

Novel small-eye allele in paired box gene 6 (Pax6) is caused by a point mutation in intron 7 and creates a new exon

H. Fuchs, V. Gailus-Durner, M. Hrabě de Angelis, 2013, Molecular vision.

Eye development.

J. Graw, 2010, Current topics in developmental biology.

Molecular dissection of Pax6 function: the specific roles of the paired domain and homeodomain in brain development

M. Götz, Anastassia Stoykova, G. Saunders, 2004, Development.

Altered Na,K-ATPase Pattern in γ-Crystallin Mutant Mice

A. Moseley, N. Delamere, J. Graw, 2002 .

Mutation in intron 6 of the hamster Mitf gene leads to skipping of the subsequent exon and creates a novel animal model for the human Waardenburg syndrome type II.

J. Graw, W. Pretsch, J. Löster, 2003, Genetics.

Application of WES towards Molecular Investigation of Congenital Cataracts: Identification of Novel Alleles and Genes in a Hospital-Based Cohort of South India

W. Berger, J. Graw, I. Magyar, 2020, International journal of molecular sciences.

Three novel Pax6 alleles in the mouse leading to the same small-eye phenotype caused by different consequences at target promoters.

Peter Nürnberg, Helmut Fuchs, Martin Hrabé de Angelis, 2005, Investigative ophthalmology & visual science.

Mouse models of congenital cataract

Jochen Graw, J. Graw, 1999, Eye.

Microphakia and congenital cataract formation in a novel Lim2C51R mutant mouse

M. Hrabě de Angelis, O. Puk, J. Graw, 2011, Molecular vision.

Mutation in Bmpr1b Leads to Optic Disc Coloboma and Ventral Retinal Gliosis in Mice

Gerhard K. H. Przemeck, H. Fuchs, J. Kremers, 2020, Investigative ophthalmology & visual science.

Functional compensation among HMGN variants modulates the DNase I hypersensitive sites at enhancers

D. Landsman, H. Fuchs, A. van der Velde, 2015, Genome research.

A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains

Henrik Westerberg, John M. Hancock, Steve D. M. Brown, 2013, Genome Biology.

Cytochrome c oxidase subunit 4 isoform 2‐knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology

H. Fuchs, D. Busch, H. Höfler, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Novel mutations in the γ-crystallin genes cause autosomal dominant congenital cataracts

P. M. Gopinath, J. Graw, P. Vijayalakshmi, 2002 .

Analysis of mammalian gene function through broad based phenotypic screens across a consortium of mouse clinics

Henrik Westerberg, John M. Hancock, Oliver Eickelberg, 2015, Nature Genetics.

Prevalence of sexual dimorphism in mammalian phenotypic traits

Steve D. M. Brown, Anneliese O. Speak, Jacqueline K. White, 2017, Nature Communications.

Fgf9Y162C Mutation Alters Information Processing and Social Memory in Mice

H. Fuchs, W. Wurst, J. Adamski, 2017, Molecular Neurobiology.

Mouse mutants as models for congenital retinal disorders.

J. Graw, C. Dalke, 2005, Experimental eye research.

CRYBA4, a novel human cataract gene, is also involved in microphthalmia.

A. Paterson, S. M. Hosseini, E. Héon, 2006, American journal of human genetics.

Three murine cataract mutants (Cat2) are defective in different gamma-crystallin genes.

N. Klopp, A. Prescott, G. Vrensen, 1998, Genomics.

Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice

H. Fuchs, D. Busch, E. Wolf, 2017, Nature Communications.

Levels of p27 Sensitize to Dual PI3K/mTOR Inhibition

N. Pellegata, M. Theodoropoulou, F. Roncaroli, 2011, Molecular Cancer Therapeutics.

Levels of p 27 Sensitize to Dual PI 3 K / mTOR Inhibition

N. Pellegata, M. Theodoropoulou, F. Roncaroli, 2011 .

Rapamycin extends murine lifespan but has limited effects on aging.

H. Fuchs, D. Busch, H. Höfler, 2013, The Journal of clinical investigation.

Dose-dependent long-term effects of a single radiation event on behaviour and glial cells

W. Wurst, H. Zitzelsberger, S. Hölter, 2020, International journal of radiation biology.

Introducing the German Mouse Clinic: open access platform for standardized phenotyping

Werner Müller, Christian Zybill, Valérie Gailus-Durner, 2005, Nature Methods.

Ethylnitrosourea-induced mutation in mice leads to the expression of a novel protein in the eye and to dominant cataracts.

H. Fuchs, E. Wolf, R. Balling, 2001, Genetics.

Posterior subcapsular cataracts are a late effect after acute exposure to 0.5 Gy ionizing radiation in mice

A. Beyerlein, J. Adamski, C. Prehn, 2021, International journal of radiation biology.

Identification of ocular regulatory functions of core histone variant H3.2.

W. Wurst, J. Graw, F. Giesert, 2022, Experimental eye research.

Claudin-12 is not required for blood–brain barrier tight junction function

H. Fuchs, D. Busch, W. Wurst, 2019, Fluids and Barriers of the CNS.

Novel mutations in the gamma-crystallin genes cause autosomal dominant congenital cataracts.

P. M. Gopinath, J. Graw, P. Vijayalakshmi, 2002, Journal of medical genetics.

The crystallins: genes, proteins and diseases.

J. Graw, 1997, Biological chemistry.

Peroxidasin is essential for eye development in the mouse

H. Fuchs, J. Beckers, V. Gailus-Durner, 2014, Human molecular genetics.

A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains

Henrik Westerberg, John M. Hancock, Steve D. M. Brown, 2013, Genome Biology.

Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice

H. Fuchs, D. Busch, W. Wurst, 2022, bioRxiv.

A new Fgf10 mutation in the mouse leads to atrophy of the harderian gland and slit-eye phenotype in heterozygotes: a novel model for dry-eye disease?

H. Fuchs, E. Wolf, P. Nürnberg, 2009, Investigative ophthalmology & visual science.

Molecular analysis of four lactate dehydrogenase-A mutants in the mouse

J. Favor, J. Graw, W. Pretsch, 1994, Mammalian Genome.

Visualizing corticotropin‐releasing hormone receptor type 1 expression and neuronal connectivities in the mouse using a novel multifunctional allele

J. Deussing, W. Wurst, G. Schütz, 2012, The Journal of comparative neurology.

Characterization of a mutation in the lens-specific MP70 encoding gene of the mouse leading to a dominant cataract.

H. Fuchs, M. Angelis, E. Wolf, 2001, Experimental eye research.

Up‐regulation of novel intermediate filament proteins in primary fiber cells: An indicator of all vertebrate lens fiber differentiation?

A. Prescott, M. Kasper, J. Graw, 2000, The Anatomical Record.

Betacellulin overexpression in transgenic mice causes disproportionate growth, pulmonary hemorrhage syndrome, and complex eye pathology.

R. Wanke, E. Wolf, N. Herbach, 2005, Endocrinology.

The Cryner element in the murine gamma-crystallin promoters interacts with lens proteins.

J. Graw, R. Augusteyn, T. Stöger, 1997, Ophthalmic research.

Effects of UV-B radiation on a hereditary suture cataract in mice.

J. Graw, A. Wegener, C. Forker, 1997, Experimental eye research.

Sequence analysis of the beta B2-crystallin cDNA of hamster containing a domain conserved among vertebrates.

T. Werner, J. Graw, J. Löster, 1996, Gene.

Murine γE-crystallin is distinct from murine γ2-crystallin

T. Werner, J. Graw, A. Liebstein, 1991 .

A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes

J. Mason, H. Fuchs, D. Busch, 2020, Mammalian Genome.

The First Scube3 Mutant Mouse Line with Pleiotropic Phenotypic Alterations

Gerhard K. H. Przemeck, H. Fuchs, D. Busch, 2016, G3: Genes, Genomes, Genetics.

Features of Age-Related Macular Degeneration in the General Adults and Their Dependency on Age, Sex, and Smoking: Results from the German KORA Study

Iris M. Heid, Caroline Brandl, Helmut Küchenhoff, 2016, PloS one.

Alpha-crystallins are involved in specific interactions with the murine gamma D/E/F-crystallin-encoding gene.

T. Werner, J. Graw, D. Pietrowski, 1994, Gene.

Mutation analysis of congenital cataracts in Indian families: identification of SNPS and a new causative allele in CRYBB2 gene.

J. Adamski, P. M. Gopinath, Sharmila Anishetty, 2004, Investigative ophthalmology & visual science.

Crybb2 Mutations Consistently Affect Schizophrenia Endophenotypes in Mice

H. Fuchs, W. Wurst, S. Hölter, 2018, Molecular Neurobiology.

Visual capabilities and cortical maps in BALB/c mice

S. Löwel, K. Lehmann, O. Puk, 2012, The European journal of neuroscience.

A mouse model for intellectual disability caused by mutations in the X-linked 2'‑O‑methyltransferase Ftsj1 gene.

J. Gécz, H. Fuchs, D. Busch, 2019, Biochimica et biophysica acta. Molecular basis of disease.

Polymorphisms in CRYBB2 encoding βB2-crystallin are associated with antisaccade performance and memory function

D. Rujescu, I. Giegling, H. Möller, 2020, Translational Psychiatry.

Molecular analysis of cataract families in India: new mutations in the CRYBB2 and GJA3 genes and rare polymorphisms

M. Platzer, N. Klopp, T. Illig, 2010, Molecular vision.

Novel allele of crybb2 in the mouse and its expression in the brain.

Wolfgang Wurst, Johannes Beckers, Marion Horsch, 2008, Investigative ophthalmology & visual science.

Altered aggregation properties of mutant γ‐crystallins cause inherited cataract

C. Dobson, N. Klopp, C. MacPhee, 2002 .

11 novel Mutations in the Factor VIII encoding Gene lead to severe or moderate Hemophilia A

N. Klopp, J. Oldenburg, R. Schwaab, 2003 .

Longitudinal fundus and retinal studies with SD-OCT: a comparison of five mouse inbred strains

Jochen Graw, M. Angelis, M. D. de Angelis, 2013, Mammalian Genome.

Expression of Crystallins, Pax6, Filensin, CP49, MIP, and MP20 in lens-derived cell lines.

C. M. Sax, E. Krausz, J. Graw, 1996, Investigative ophthalmology & visual science.

A novel GJA8 mutation causing a recessive triangular cataract

N. Klopp, T. Illig, J. Graw, 2008, Molecular vision.

Streptozotocin-induced β-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain

H. Fuchs, D. Busch, E. Wolf, 2018, Scientific Reports.

Agonistic and Antagonistic Action of AP2, Msx2, Pax6, Prox1 and Six3 in the Regulation of Sox2 Expression

J. Lengler, J. Graw, A. E. Gawad, 2005, Ophthalmic Research.

[The national GTH haemophilia registry as database within the scope of the German human genome project].

J. Oldenburg, R. Schwaab, W. Schramm, 2003, Hamostaseologie.

Pleiotropic Functions for Transcription Factor Zscan10

H. Fuchs, D. Busch, E. Wolf, 2014, PloS one.

Radiation Cataractogenesis: A Review of Recent Studies

C. Muirhead, S. Bouffler, E. Ainsbury, 2009, Radiation research.

Mice with an induced mutation in collagen 8A2 develop larger eyes and are resistant to retinal ganglion cell damage in an experimental glaucoma model

H. Quigley, T. Nguyen, E. Oglesby, 2012, Molecular vision.

The KORA Eye Study: a population-based study on eye diseases in Southern Germany (KORA F4).

R. Holle, W. Rathmann, A. Peters, 2011, Investigative ophthalmology & visual science.

On the use of Tono-Pen XL for the measurement of intraocular pressure in mice.

U. Pleyer, J. Graw, C. Dalke, 2005, Experimental eye research.

The Pathologic Effect of a Novel Neomorphic Fgf9Y162C Allele Is Restricted to Decreased Vision and Retarded Lens Growth

J. Adamski, M. D. de Angelis, G. Möller, 2011, PloS one.

Mutations within the cGMP-binding domain of CNGA1 causing autosomal recessive retinitis pigmentosa in human and animal model

Gerhard K. H. Przemeck, H. Fuchs, M. Biel, 2022, Cell Death Discovery.

Complex Long-term Effects of Radiation on Adult Mouse Behavior

J. Graw, C. Dalke, Annemarie Zimprich, 2021, Radiation Research.

CREB Signaling Mediates Dose-dependent Radiation Response in the Murine Hippocampus Two Years after Total Body Exposure.

D. Hladik, S. Tapio, S. Hauck, 2019, Journal of proteome research.

V76D mutation in a conserved gD-crystallin region leads to dominant cataracts in mice

Helmut Fuchs, André Reis, Eckhard Wolf, 2002, Mammalian Genome.

Laboratory mouse housing conditions can be improved using common environmental enrichment without compromising data

H. Fuchs, E. Wolf, W. Wurst, 2018, PLoS biology.

An in vivo doxycycline-controlled expression system for functional studies of the retina.

A. Ballabio, F. Gekeler, A. Auricchio, 2003, Investigative ophthalmology & visual science.

Standardized, systemic phenotypic analysis of Slc12a1I299F mutant mice

H. Fuchs, D. Busch, E. Wolf, 2014, Journal of Biomedical Science.

Innovations in phenotyping of mouse models in the German Mouse Clinic

H. Fuchs, D. Busch, H. Höfler, 2012, Mammalian Genome.

From eyeless to neurological diseases.

J. Graw, 2017, Experimental eye research.

Neutralizing IL-17 protects the optic nerve from autoimmune pathology and prevents retinal nerve fiber layer atrophy during experimental autoimmune encephalomyelitis.

Bernhard Hemmer, Thomas Korn, Jochen Graw, 2015, Journal of autoimmunity.

Altered aggregation properties of mutant gamma-crystallins cause inherited cataract.

C. Dobson, N. Klopp, C. MacPhee, 2002, The EMBO journal.

Requirement of the RNA-editing Enzyme ADAR2 for Normal Physiology in Mice*

H. Fuchs, D. Busch, P. Seeburg, 2011, The Journal of Biological Chemistry.

Longitudinal fundus and retinal studies with SD-OCT: a comparison of five mouse inbred strains

M. Angelis, O. Puk, J. Graw, 2013, Mammalian Genome.

On the Nature of Murine Radiation-Induced Subcapsular Cataracts: Optical Coherence Tomography-Based Fine Classification, In Vivo Dynamics and Impact on Visual Acuity

H. Fuchs, M. D. de Angelis, V. Gailus-Durner, 2021, Radiation Research.

Spectral domain - Optical coherence tomography (SD-OCT) as a monitoring tool for alterations in mouse lenses.

Helmut Fuchs, Valerie Gailus-Durner, Daniel Pawliczek, 2019, Experimental eye research.

Lifetime study in mice after acute low-dose ionizing radiation: a multifactorial study with special focus on cataract risk

M. Rosemann, W. Wurst, H. Zitzelsberger, 2018, Radiation and environmental biophysics.

Variation of the response to the optokinetic drum among various strains of mice.

Martin Hrabé de Angelis, Claudia Dalke, Jochen Graw, 2008, Frontiers in bioscience : a journal and virtual library.

Lens density tracking in mice by Scheimpflug imaging

M. Angelis, O. Puk, J. Graw, 2013, Mammalian Genome.

Crybb2 associates with Tmsb4X and is crucial for dendrite morphogenesis.

J. Graw, N. Ahmad, Minxuan Sun, 2018, Biochemical and biophysical research communications.

Microphthalmia, parkinsonism, and enhanced nociception in Pitx3416insG mice

H. Fuchs, M. Angelis, M. Rosemann, 2010, Mammalian Genome.

Ethylnitrosourea-induced base pair substitution affects splicing of the mouse gammaE-crystallin encoding gene leading to the expression of a hybrid protein and to a cataract.

N. Klopp, J. Favor, J. Graw, 2002, Genetics.

Characterization of a 1-bp deletion in the gammaE-crystallin gene leading to a nuclear and zonular cataract in the mouse.

N. Klopp, J. Graw, J. Löster, 2001, Investigative ophthalmology & visual science.

Further Genetic Heterogeneity for Autosomal Dominant Human Sutural Cataracts

M. Wjst, N. Klopp, T. Illig, 2003, Ophthalmic Research.

REVIEW Radiation Cataractogenesis: A Review of Recent Studies

C. Muirhead, Oxford Ox, S. Bouffler, 2009 .

A novel CRYGC E128* mutation underlying an autosomal dominant nuclear cataract in a south Indian kindred

K. Vasantha, J. Graw, Dinesh Kumar Kandaswamy, 2020, Ophthalmic genetics.

Aphakia (ak), a mouse mutation affecting early eye development: fine mapping, consideration of candidate genes and altered Pax6 and Six3 gene expression pattern.

N. Klopp, J. Favor, J. Graw, 1998, Developmental genetics.

A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction

Steve D. M. Brown, N. Karp, J. Mason, 2017, Nature Communications.

Regulation of the human SIX3 gene promoter.

J. Lengler, J. Graw, 2001, Biochemical and biophysical research communications.

The First Scube3 Mutant Mouse Line with Pleiotropic Phenotypic Alterations

Gerhard K. H. Przemeck, H. Fuchs, D. Busch, 2016, G3: Genes, Genomes, Genetics.

Induction of gene mutations in mice: the multiple endpoint approach.

J. Favor, J. Graw, W. Pretsch, 1985, Progress in clinical and biological research.

Common eye diseases in older adults of southern Germany: results from the KORA-Age study

R. Strobl, E. Grill, H. Grallert, 2016, Age and ageing.

Close linkage of the dominant cataract mutations (Cat-2) with Idh-1 and cryge on mouse chromosome 1.

M. Lyon, J. Graw, T. Schmitt-John, 1994, Genomics.

Polymorphism in the murine Tr2-11 gene encoding an orphan receptor, and its exclusion as a candidate gene for the cataract mutation Cat3.

J. Adamski, J. Graw, T. Immervoll, 1998, Biological chemistry.

Murine gamma E-crystallin is distinct from murine gamma 2-crystallin.

T. Werner, J. Graw, A. Liebstein, 1991, Gene.

Reduced levels of γ-crystallin transcripts during embryonic development of murine Cat2nop mutant lenses

J. Graw, J. Löster, S. Santhiya, 1995, Graefe's Archive for Clinical and Experimental Ophthalmology.

Rapamycin extends murine lifespan but has limited effects on aging.

H. Fuchs, D. Busch, H. Höfler, 2013, The Journal of clinical investigation.

Allelic loss of chromosomes 8 and 19 in MENX‐associated rat pheochromocytoma

N. Pellegata, S. Chevillard, M. Atkinson, 2009, International journal of cancer.

Crybb2 Mutations Consistently Affect Schizophrenia Endophenotypes in Mice

H. Fuchs, W. Wurst, S. Hölter, 2018, Molecular Neurobiology.

From eyeless to neurological diseases.

J. Graw, 2017, Experimental eye research.

Neutralizing IL-17 protects the optic nerve from autoimmune pathology and prevents retinal nerve fiber layer atrophy during experimental autoimmune encephalomyelitis.

B. Hemmer, T. Korn, Sylvia Heink, 2015, Journal of autoimmunity.

A comparative phenotypic and genomic analysis of C 57 BL / 6 J and C 57 BL / 6 N mouse strains

Thomas M. Keane, H. Fuchs, A. Mallon, 2013 .

Cataract mutations as a tool for developmental geneticists.

J. Graw, 1996, Ophthalmic research.

Mutation in a novel connexin-like gene (Gjf1) in the mouse affects early lens development and causes a variable small-eye phenotype.

H. Fuchs, E. Wolf, M. D. de Angelis, 2008, Investigative ophthalmology & visual science.

Molecular analysis of cataract families in India: new mutations in the CRYBB2 and GJA3 genes and rare polymorphisms

M. Platzer, N. Klopp, T. Illig, 2010, Molecular vision.

Imbalances in the eye lens proteome are linked to cataract formation

J. Buchner, T. Madl, M. Haslbeck, 2021, Nature Structural & Molecular Biology.