N. Kang

发表

The core regulatory network in human cells.

Dongsan Kim, M. Kim, N. Kang, 2017, Biochemical and biophysical research communications.

Classification models for CYP450 3A4 inhibitors and non-inhibitors.

Nam Sook Kang, Kyoung Tai No, Jihoon Jung, 2009, European journal of medicinal chemistry.

The Predictive QSAR Model for hERG Inhibitors Using Bayesian and Random Forest Classification Method

Chong Hak Chae, Nam Sook Kang, N. Kang, 2011 .

Binding free energies of inhibitors to iron porphyrin complex as a model for Cytochrome P450.

Joo Yun Lee, Y. Kang, N. Kang, 2012, Biopolymers.

The structure-based 3D-QSAR study of MCH1 receptor antagonists

N. Kang, Seung-Eun Yoo, New Gil Lee, 2008 .

Quantitative assessment of kinase selectivity based the water-ring network in protein binding sites using molecular dynamics simulations

N. Kang, W. Jang, Myeong Hwi Lee, 2016 .

The discovery of inhibitors of Fas-mediated cell death pathway using the combined computational method.

Eun Hee Kim, N. Kang, Seung-Eun Yoo, 2013, Bioorganic & medicinal chemistry letters.

Method Validation for Equilibrium Solubility and Determination of Temperature Effect on the Ionization Constant and Intrinsic Solubility of Drugs

Bo Kyung Kim, N. Kang, Kyoowon Baek, 2018 .

Computational insights into the role of α-strand/sheet in aggregation of α-synuclein

A. Balupuri, N. Kang, Kwang-Eun Choi, 2019, Scientific Reports.

Topological Water Network Analysis Around Amino Acids

A. Balupuri, N. Kang, Kwang-Eun Choi, 2019, Molecules.

Augmentation of PPARgamma-TAZ interaction contributes to the anti-adipogenic activity of KR62980.

N. Kang, E. Hwang, S. Yoo, 2009, Biochemical pharmacology.

Design of a Novel and Selective IRAK4 Inhibitor Using Topological Water Network Analysis and Molecular Modeling Approaches

A. Balupuri, Sungwook Choi, N. Kang, 2018, Molecules.

Liquid chromatography–tandem mass spectrometry of recombinant human extracellular superoxide dismutase (rhSOD3) in mouse plasma and its application to pharmacokinetic study

Weontae Lee, N. Kang, Tae-Yoon Kim, 2019, Journal of pharmaceutical and biomedical analysis.

Ionic interactions for substituted MCH1R inhibitors studied by pK(a) values.

Joo Yun Lee, N. Kang, Jung Yun Lim, 2009, Bioorganic & medicinal chemistry letters.

Pharmacophoric Site Identification and Inhibitor Design for Autotaxin

A. Balupuri, N. Kang, Myeong Hwi Lee, 2019, Molecules.

Synthesis, anticancer activity and pharmacokinetic analysis of 1-[(substituted 2-alkoxyquinoxalin-3-yl)aminocarbonyl]-4-(hetero)arylpiperazine derivatives.

N. Kang, C. Ahn, Y. Gong, 2012, Bioorganic & medicinal chemistry.

Bayesian Model for the Classification of GPCR Agonists and Antagonists

K. No, Ky-Youb Nam, Inhee Choi, 2010 .

A Novel 6-(2-methyl-2-alkylsubstituted-2H-chromen-6-yl)-amine Derivatives and Pharmacophore Model as 5-Lipoxygenase Inhibitors

H. Cheon, N. Kang, Y. Gong, 2011 .

Identification of 4-[4-(4-Fluoro-Phenyl)-Thiazol-2-Ylamino]-2,6-Dimethyl-Phenol (KR-33749) as an Inhibitor of 5-Lipoxygenase with Potent Antiinflammatory Activity

C. Kim, H. Cheon, N. Kang, 2010, Pharmacology.

Identification of cyclicsulfonamide derivatives with an acetamide group as 11β-hydroxysteroid dehydrogenase 1 inhibitors.

C. Kim, N. Kang, S. Rhee, 2011, Chemical & pharmaceutical bulletin.

Molecular Dynamics Studies on the Structural Stability Prediction of SARS-CoV-2 Variants Including Multiple Mutants

Jeong-Min Kim, N. Kang, C. Yoo, 2022, International journal of molecular sciences.

A Novel 3-(8-Chloro-6-(trifluoromethyl)imidazo(1,2-a)pyridine-2-yl)phenyl Acetate Skeleton and Pharmacophore Model as Glucagon-like Peptide 1 Receptor Agonists

H. Cheon, N. Kang, Y. Gong, 2010 .

The discovery of bioisoster compound for plumbagin using the knowledge-based rational method

N. Kang, Jung-Sup Choi, Y. Ko, 2015 .

Predictive models of Cannabinoid-1 receptor antagonists derived from diverse classes.

N. Kang, S. Yoo, Gil Nam Lee, 2009, Bioorganic & medicinal chemistry letters.

Synthesis and Biological Evaluation of Maleimide Derivatives for Neuronal Differentiation

N. Kang, M. Bae, J. Ahn, 2009 .

Discovery of non-LBD inhibitor for androgen receptor by structure-guide design.

N. Kang, Nakjeong Kim, S. Yoo, 2013, Bioorganic & medicinal chemistry letters.

The Discovery of Aurora Kinase Inhibitor by Multi-Docking-Based Virtual Screening

C. Ryu, Jun-Tae Kim, N. Kang, 2014, International journal of molecular sciences.

Quantitative determination of enzalutamide, an anti-prostate cancer drug, in rat plasma using liquid chromatography-tandem mass spectrometry, and its application to a pharmacokinetic study.

N. Kang, Ji-Hye Song, Nakjeong Kim, 2014, Biomedical chromatography : BMC.

Discovery of aminopyridines substituted with benzoxazole as orally active c-Met kinase inhibitors.

N. Kang, H. Jung, Sun-Young Han, 2010, Bioorganic & medicinal chemistry letters.

c-Met and ALK Inhibitory Constituents from Scutellaria baicalensis

Hyuk Song, Y. Chin, N. Kang, 2015 .

Synthesis, biological evaluation and structural determination of beta-aminoacyl-containing cyclic hydrazine derivatives as dipeptidyl peptidase IV (DPP-IV) inhibitors.

Jie-Oh Lee, S. Kim, Sung Soo Kim, 2007, Bioorganic & medicinal chemistry letters.

Design and Synthesis of a Novel 4-aryl-N-(2-alkoxythieno [2,3-b]pyrazine-3-yl)-4-arylpiperazine-1-carboxamide DGG200064 Showed Therapeutic Effect on Colon Cancer through G2/M Arrest

Nayeon Kim, N. Kang, Aizhan Abdildinova, 2022, Pharmaceuticals.

A Study on the Effect of the Substituent against PAK4 Inhibition Using In Silico Methods

N. Kang, Hye Ree Yoon, Chong‐Chul Chai, 2022, International journal of molecular sciences.

High-Throughput Platform for Real-Time Monitoring of ATP-generating Enzymes in Living Cells Based on a Lanthanide Probe.

A. Balupuri, M. Gabr, N. Kang, 2020, ACS sensors.

Enzyme Kinetics and Molecular Docking Studies on Cytochrome 2B6, 2C19, 2E1, and 3A4 Activities by Sauchinone

A. Balupuri, Y. Choi, Y. Chin, 2018, Molecules.

SB365, Pulsatilla saponin D, targets c-Met and exerts antiangiogenic and antitumor activities.

N. Kang, Soon-Sun Hong, K. Jung, 2013, Carcinogenesis.

Euphorbiasteroid reverses P‐glycoprotein‐mediated multi‐drug resistance in human sarcoma cell line MES‐SA/Dx5

N. Kang, Y. Min, Jung-Sook Choi, 2009, Phytotherapy research : PTR.

A novel RIPK1 inhibitor that prevents retinal degeneration in a rat glaucoma model

N. Kang, Eunhee Kim, Ki-Hong Jang, 2017, Experimental cell research.

Synthesis and biological evaluation of pyrazoline analogues with beta-amino acyl group as dipeptidyl peptidase IV inhibitors.

Jie-Oh Lee, Sung Soo Kim, H. Cheon, 2008, European journal of medicinal chemistry.

Synthesis and biological evaluation of homopiperazine derivatives with beta-aminoacyl group as dipeptidyl peptidase IV inhibitors.

Jie-Oh Lee, Sung Soo Kim, H. Cheon, 2008, Bioorganic & medicinal chemistry letters.

A Novel 3‐(8‐Chloro‐6‐(trifluoromethyl)imidazo[1,2‐a]pyridine‐2‐yl)phenyl Acetate Skeleton and Pharmacophore Model as Glucagon‐Like Peptide 1 Receptor Agonists.

H. Cheon, N. Kang, Y. Gong, 2011 .

Conformational preferences of N‐methoxycarbonyl proline dipeptide

Nam Sook Kang, Young Kee Kang, Y. Kang, 2009, J. Comput. Chem..

Suppression of Adipocyte Differentiation by Foenumoside B from Lysimachia foenum-graecum Is Mediated by PPARγ Antagonism

H. Cheon, N. Kang, H. Kwak, 2016, PloS one.

Cooperative phosphorylation of FADD by Aur-A and Plk1 in response to taxol triggers both apoptotic and necrotic cell death.

Su-Jin Lee, N. Kang, Eunhee Kim, 2011, Cancer research.

Assessment of CCSD(T), MP2, and DFT methods for the calculations of structures and interaction energies of the peptide backbone with water molecules

Y. Kang, N. Kang, 2017 .

KRC-408, a novel c-Met inhibitor, suppresses cell proliferation and angiogenesis of gastric cancer.

N. Kang, Soon-Sun Hong, Hong-Mei Zheng, 2013, Cancer letters.

The discovery and the structural basis of an imidazo[4,5-b]pyridine-based p21-activated kinase 4 inhibitor.

Sunmin Kim, SangYoun Park, N. Kang, 2016, Bioorganic & medicinal chemistry letters.

Docking-based 3D-QSAR study for selectivity of DPP4, DPP8, and DPP9 inhibitors.

Chong Hak Chae, Sung-Eun Yoo, Nam Sook Kang, 2007, Bioorganic & medicinal chemistry letters.

Aggregation Mechanism of Alzheimer’s Amyloid β-Peptide Mediated by α-Strand/α-Sheet Structure

A. Balupuri, N. Kang, Kwang-Eun Choi, 2020, International journal of molecular sciences.

Identification of small molecules that inhibit GSK-3beta through virtual screening.

Nam Sook Kang, Chi Hyun Kim, Young Sik Cho, 2009, Bioorganic & medicinal chemistry letters.

Design and synthesis of triazolopyridazines substituted with methylisoquinolinone as selective c-Met kinase inhibitors.

N. Kang, H. Jung, Sang-Un Choi, 2011, Bioorganic & medicinal chemistry letters.

Discovery and optimization of ATX inhibitors via modeling, synthesis and biological evaluation.

A. Balupuri, N. Kang, T. Koo, 2018, European journal of medicinal chemistry.

Design, synthesis, docking and biological evaluation of 4-phenyl-thiazole derivatives as autotaxin (ATX) inhibitors.

A. Balupuri, N. Kang, Myeong Hwi Lee, 2017, Bioorganic & medicinal chemistry letters.

Inhibition of STAT3 activation by KT-18618 via the disruption of the interaction between JAK3 and STAT3.

D. Han, C. Lee, B. Kwon, 2014, Biochemical pharmacology.

Identification of 3-hydroxy-2-(3-hydroxyphenyl)-4H-1-benzopyran-4-ones as isoform-selective PKC-zeta inhibitors and potential therapeutics for psychostimulant abuse.

W. Wetsel, D. Beratan, S. Keinan, 2009, Molecular bioSystems.

Docking and 3-D QSAR studies of dual PDE4-PDE7 inhibitors

N. Kang, S. Yoo, J. Song, 2007 .

Study on the hydrolysis mechanism of phosphodiesterase 4 using molecular dynamics simulations

N. Kang, C. Chae, S. Yoo, 2006 .

Effect of novel N-cyano-tetrahydro-pyridazine compounds, a class of cathepsin K inhibitors, on the bone resorptive activity of mature osteoclasts.

N. Kang, J. Song, S. Kim, 2008, Bioorganic & medicinal chemistry letters.

Anti-diabetic and anti-inflammatory effect of a novel selective 11β-HSD1 inhibitor in the diet-induced obese mice.

H. Jeong, S. B. Park, W. Jung, 2013, European journal of pharmacology.

A Study of the Hydrogen-bonded Network Around the Left-handed and Right-handed DNA in an Ionic Solution

M. Jhon, N. Kang, K. T. No, 2003 .

A novel 3-arylethynyl-substituted pyrido[2,3,-b]pyrazine derivatives and pharmacophore model as Wnt2/β-catenin pathway inhibitors in non-small-cell lung cancer cell lines.

Nayeon Kim, M. Dong, N. Kang, 2011, Bioorganic & medicinal chemistry.

Inhibition of β-site amyloid precursor protein cleaving enzyme 1 and cholinesterases by pterosins via a specific structure−activity relationship with a strong BBB permeability

S. Hong, A. Balupuri, G. Park, 2019, Experimental & Molecular Medicine.

Characterization of Binding Mode for Human Coagulation Factor XI (FXI) Inhibitors

N. Kang, S. Jung, Jun Tae Kim, 2013 .

Molecular Dynamics Studies on the Structural Characteristics for the Stability Prediction of SARS-CoV-2

Jeong-Min Kim, N. Kang, Kwang-Eun Choi, 2021, International journal of molecular sciences.

Binding Mode Identification for 7-keto-8-Aminopelargonic Acid Synthase (AtKAPAS) Inhibitors

I. Hwang, N. Kang, Jung-sup Choi, 2015 .

The Identification of Binding Mode for Arabidopsis thaliana 7-Keto-8-aminopelargonic Acid Synthase (AtKAPAS) Inhibitors

I. Hwang, N. Kang, Y. Ko, 2012 .

Molecular dynamics study on the electrostatic effect of protein conformation

Jae Kwang Shin, M. John, N. Kang, 1993 .

Discovery of a potent small molecule SIRT1/2 inhibitor with anticancer effects.

N. Kang, Sun-Young Han, G. Choi, 2013, International journal of oncology.

Systemic optimization and structural evaluation of quinoline derivatives as transthyretin amyloidogenesis inhibitors.

Sungwook Choi, Sung Jean Park, N. Kang, 2016, European journal of medicinal chemistry.

Discovery of new inhibitor for PDE3 by virtual screening.

Ki Young Kim, N. Kang, S. Yoo, 2011, Bioorganic & medicinal chemistry letters.

Predictive Model for Drug-Induced Liver Injury Using Deep Neural Networks Based on Substructure Space

N. Kang, Myung-Gyun Kang, 2021, Molecules.

Camphoric acid stimulates osteoblast differentiation and induces glutamate receptor expression

N. Kang, Y. Min, S. Kim, 2008, Amino Acids.

Anti-diabetic and anti-adipogenic effects of a novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor, 2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone (KR-66344).

W. Jung, H. Cheon, N. Kang, 2011, Biochemical pharmacology.

Discovery of Tyk2 inhibitors via the virtual site-directed fragment-based drug design.

Jun-Tae Kim, N. Kang, Y. Cho, 2015, Bioorganic & medicinal chemistry letters.

Pressure and Temperature Dependence Study of the Denaturation of Ribonuclease A Solutions

M. Jhon, N. Kang, J. Yu, 1995 .

The Study on the hERG Blocker Prediction Using Chemical Fingerprint Analysis

Kwang-Eun Choi, Anand Balupuri, Nam Sook Kang, 2020, Molecules.

Anti-diabetic and anti-adipogenic effects of a novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor in the diet-induced obese mice.

W. Jung, N. Kang, S. Rhee, 2012, European journal of pharmacology.

Discovery of structural characteristics of RIP1K for activity control using the combination method

N. Kang, Eunhee Kim, Yun‐Ju Do, 2015 .

Small Molecule Inhibitors of DYRK1A Identified by Computational and Experimental Approaches

A. Balupuri, N. Kang, Kwang-Eun Choi, 2020, International journal of molecular sciences.

Discovery of β-aminoacyl containing thiazolidine derivatives as potent and selective dipeptidyl peptidase IV inhibitors.

Jie-Oh Lee, Sung Soo Kim, S. Schneider, 2011, Bioorganic & medicinal chemistry letters.

A Novel 3-Phenylethynyl-2-yl-oxy Quinoxaline Core Skeleton and Pharmacophore Model as a Hypoxia-inducible Factor Inhibitor

N. Kang, Y. Gong, 2010 .

A Novel Phenylimidazo[1,2-α]pyridine Core Skeleton and Pharmacophore Model as Hypoxia-Inducible Factor Inhibitors

N. Kang, Y. Gong, 2010 .

ADis-QSAR: a machine learning model based on biological activity differences of compounds

N. Kang, Gyoung Jin Park, 2023, Journal of Computer-Aided Molecular Design.

Optimization of cyclic sulfamide derivatives as 11β-hydroxysteroid dehydrogenase 1 inhibitors for the potential treatment of ischemic brain injury.

S. B. Park, W. Jung, J. H. Lee, 2019, Bioorganic & medicinal chemistry letters.

Cardiovascular effects of a novel selective Rho kinase inhibitor, 2-(1H-indazole-5-yl)amino-4-methoxy-6-piperazino triazine (DW1865).

H. Seo, N. Kang, B. Oh, 2013, European journal of pharmacology.

Computational insights into the role of α-strand/sheet in aggregation of α-synuclein

A. Balupuri, N. Kang, Kwang-Eun Choi, 2019, Scientific Reports.

The Discovery of New Human Coagulation Factor XIa (FXIa) Inhibitors by Synthesis, Biological Evaluation, and Structure‐based Modeling

N. Kang, Jinyeong Kim, Myeong Hwi Lee, 2016 .

Reactivation potency of fluorinated pyridinium oximes for acetylcholinesterases inhibited by paraoxon organophosphorus agent.

N. Park, N. Kang, Young-Sik Jung, 2009, Bioorganic & medicinal chemistry letters.

Comparative molecular field analysis (CoMFA) for phosphodiesterase (PDE) IV inhibitors

N. Kang, S. Yoo, C. Chae, 2007 .

Design and synthesis of fluorescent and biotin tagged probes for the study of molecular actions of FAF1 inhibitor.

N. Kang, Eunhee Kim, S. Yoo, 2016, Bioorganic & medicinal chemistry letters.

Synthesis and anti-influenza virus activity of 4-oxo- or thioxo-4,5-dihydrofuro[3,4-c]pyridin-3(1H)-ones

N. Kang, Chong-kyo Lee, Ye-Jin Jang, 2014, Antiviral Research.

Effect of cosolvent on a tripeptide solution using molecular dynamics simulations

M. Jhon, N. Kang, Jeongmin Yu, 1995 .

The analysis of water network for kinase selectivity based on the MD simulations

N. Kang, W. Jang, Jun Tae Kim, 2014 .