G. Keaney

发表

Cancer-Associated SF3B1 Hotspot Mutations Induce Cryptic 3' Splice Site Selection through Use of a Different Branch Point.

M. Warmuth, Shouyong Peng, K. Kunii, 2015, Cell reports.

H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers

M. Warmuth, Shouyong Peng, O. Abdel-Wahab, 2018, Nature Medicine.

Total synthesis of 6-deoxypladienolide D and Assessment of Splicing Inhibitory Activity in a Mutant SF3B1 cancer cell line.

M. Hao, M. Warmuth, Peter G. Smith, 2014, Organic letters.

Total synthesis of (+/-)-kalihinol C.

G. Keaney, J. L. Wood, Ryan D. White, 2004, Organic letters.

H3B-8800, an Orally Bioavailable Modulator of the SF3b Complex, Shows Efficacy in Spliceosome-Mutant Myeloid Malignancies

M. Warmuth, O. Abdel-Wahab, B. Caleb, 2016 .

Synthesis of an octahydroindolinone scaffold for a diversity-based chemical compound library

G. Keaney, C. Johannes, 2007 .

Rhodium perfluorobutyramide (Rh2(pfm)4 ) : a synthetically useful catalyst for olefin aziridinations

G. Keaney, J. L. Wood, J. Wood, 2005 .

Abstract 1891: Pharmacological target validation studies of fatty acid synthase in carcinoma using the potent, selective and orally bioavailable inhibitor IPI-9119.

Lawrence W. C. Chan, M. Loda, S. Peluso, 2013 .

456 SF3B1 mutations induce disease relevant aberrant mRNA splicing in cancer and confer sensitivity to spliceosome inhibition

M. Warmuth, K. Kunii, D. Aird, 2014 .

21 SF3B1 MUTATIONS INDUCE ABERRANT SPLICING LEADING TO A BLOCK IN ERYTHROID DIFFERENTIATION AND COMPETITIVE ADVANTAGE

B. Ebert, M. Warmuth, Shouyong Peng, 2015 .

H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers

M. Warmuth, Shouyong Peng, O. Abdel-Wahab, 2018, Nature Medicine.

Abstract 2932: SF3B1 mutations induce aberrant mRNA splicing in cancer and confer sensitivity to spliceosome inhibition

M. Warmuth, K. Kunii, J. Feala, 2014 .

Cancer-Associated Mutations in SF3B1 Exhibit Neomorphic Splicing Activity and Block Erythroid Differentiation

B. Ebert, M. Warmuth, K. Kunii, 2014 .