H. Troy

发表

Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of the choline kinase inhibitor MN58b in human carcinoma models.

J. Griffiths, M. Leach, P. Workman, 2006, Cancer research.

Noninvasive Measurements of Capecitabine Metabolism in Bladder Tumors Overexpressing Thymidine Phosphorylase by Fluorine-19 Magnetic Resonance Spectroscopy

A. Harris, J. Griffiths, M. Leach, 2004, Clinical Cancer Research.

Cancer esearch cular and Cellular Pathobiology ression Profiling in Progressive Stages of Fumarate-ratase Deficiency : The Contribution of Metabolic R nges to Tumorigenesis

L. Aaltonen, E. Volpi, B. Spencer‐Dene, 2010 .

Glut-1 as a therapeutic target: increased chemoresistance and HIF-1-independent link with cell turnover is revealed through COMPARE analysis and metabolomic studies

R. Airley, J. Griffiths, S. Hewitt, 2008, Cancer Chemotherapy and Pharmacology.

Dichloroacetate induces autophagy in colorectal cancer cells and tumours

J. Griffiths, J. Griffiths, D. Koh, 2014, British Journal of Cancer.

Metabolic biomarkers of response to the AKT inhibitor MK-2206 in pre-clinical models of human colorectal and prostate carcinoma

M. Leach, S. Robinson, T. Yap, 2018, British Journal of Cancer.

Dichloroacetate treatment resulted in a dramatic drop in the conversion of hyperpolarised 1-13 C labelled pyruvate to lactate in human colon carcinoma cells

J. Griffiths, M. Leach, I. Judson, 2009 .

Evaluation of 31P high‐resolution magic angle spinning of intact tissue samples

J. Griffiths, M. Leach, G. Payne, 2006, NMR in biomedicine.

Loss of PKC- (cid:1) alters cardiac metabolism

M. Mayr, U. Mayr, J. Griffiths, 2004 .

Histone deacetylase inhibition increases levels of choline kinase alpha and phosphocholine facilitating non-invasive imaging in human cancers

J. Griffiths, M. Leach, P. Workman, 2011 .

Molecular and Cellular Pathobiology Expression Profiling in Progressive Stages of Fumarate- Hydratase Deficiency: the Contribution of Metabolic Changes to Tumorigenesis

Ian Tomlinson, Yuen-Li Chung, L. Aaltonen, 2022 .

Magnetic resonance spectroscopic pharmacodynamic markers of the heat shock protein 90 inhibitor 17-allylamino,17-demethoxygeldanamycin (17AAG) in human colon cancer models.

J. Griffiths, M. Leach, P. Workman, 2003, Journal of the National Cancer Institute.

Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of a novel histone deacetylase inhibitor, LAQ824, in human colon carcinoma cells and xenografts.

P. Atadja, J. Griffiths, M. Leach, 2008, Neoplasia.

Effects of HIF-1α and HIF2α on Growth and Metabolism of Clear-Cell Renal Cell Carcinoma 786-0 Xenografts

A. Harris, J. Griffiths, K. Gatter, 2010, Journal of oncology.

Metabolic profiling of hypoxia-inducible factor-1β-deficient and wild type Hepa-1 cells: effects of hypoxia measured by 1H magnetic resonance spectroscopy

M. Mayr, A. Harris, J. Griffiths, 2006, Metabolomics.

Proteomic and Metabolomic Analyses of Atherosclerotic Vessels From Apolipoprotein E-Deficient Mice Reveal Alterations in Inflammation, Oxidative Stress, and Energy Metabolism

Manuel Mayr, Yanhua Hu, Salim Fredericks, 2005, Arteriosclerosis, thrombosis, and vascular biology.

Loss of PKC-δ alters cardiac metabolism

Qingbo Xu, M. Mayr, U. Mayr, 2004 .

Increased tumour extracellular pH induced by Bafilomycin A1 inhibits tumour growth and mitosis in vivo and alters 5-fluorouracil pharmacokinetics.

J. Griffiths, M. Leach, I. Judson, 2003, European journal of cancer.

Adaptation to HIF-1 deficiency by upregulation of the AMP/ATP ratio and phosphofructokinase activation in hepatomas

M. Mayr, A. Harris, D. Perrett, 2011, BMC Cancer.

Loss of PKC-delta alters cardiac metabolism.

Qingbo Xu, M. Mayr, U. Mayr, 2004, American journal of physiology. Heart and circulatory physiology.

Overexpression of dimethylarginine dimethylaminohydrolase enhances tumor hypoxia: an insight into the relationship of hypoxia and angiogenesis in vivo.

J. Griffiths, S. Robinson, H. Troy, 2004, Neoplasia.

Metabolic changes detected by in vivo magnetic resonance studies of HEPA-1 wild-type tumors and tumors deficient in hypoxia-inducible factor-1beta (HIF-1beta): evidence of an anabolic role for the HIF-1 pathway.

John R Griffiths, Yuen-Li Chung, Simon P Robinson, 2002, Cancer research.

Ischemic preconditioning exaggerates cardiac damage in PKC-δ null mice

Otmar Pachinger, John R. Griffiths, Manuel Mayr, 2004 .

Ischemic preconditioning exaggerates cardiac damage in PKC-delta null mice.

Otmar Pachinger, Manuel Mayr, Michael J Dunn, 2004, American journal of physiology. Heart and circulatory physiology.

Pharmacokinetic measurements of a 5FU pro-drug, capecitabine, in bladder tumours over-expressing thymidine phosphorylase.

A. Harris, J. Griffiths, M. Leach, 2003 .

Adaptation to HIF-1 deficiency by upregulation of the AMP/ATP ratio and phosphofructokinase activation in hepatomas

H. Troy, Yuen-Li Chung, J. Latigo, 2011, BMC Cancer.

Expression profiling in progressive stages of fumarate-hydratase deficiency: the contribution of metabolic changes to tumorigenesis.

L. Aaltonen, B. Spencer‐Dene, K. Howarth, 2010, Cancer research.

CAN-10-1949 Cancer esearch cular and Cellular Pathobiology ression Profiling in Progressive Stages of Fumarate-ratase Deficiency : The Contribution of Metabolic R nges to Tumorigenesis

L. Aaltonen, E. Volpi, B. Spencer‐Dene, 2010 .

Histone deacetylase inhibition increases levels of choline kinase α and phosphocholine facilitating noninvasive imaging in human cancers.

J. Griffiths, M. Leach, P. Workman, 2012, Cancer research.