J. Malthouse

发表

Effect of acute dietary standardization on the urinary, plasma, and salivary metabolomic profiles of healthy humans.

M. Walsh, L. Brennan, M. Gibney, 2006, The American journal of clinical nutrition.

Impact of the gliotoxin l-serine-O-sulphate on cellular metabolism in cultured rat astrocytes

L. Brennan, P. Alves, J. Malthouse, 2006, Neurochemistry International.

Gliotoxins disrupt alanine metabolism and glutathione production in C6 glioma cells: a 13C NMR spectroscopic study

L. Brennan, J. Malthouse, G. McBean, 2004, Neurochemistry International.

Vinyl sulfone-based peptidomimetics as anti-trypanosomal agents: design, synthesis, biological and computational evaluation.

Andrew J. S. Knox, D. Nolan, J. Malthouse, 2013, Journal of medicinal chemistry.

13C NMR analysis reveals a link between L-glutamine metabolism, D-glucose metabolism and γ-glutamyl cycle activity in a clonal pancreatic beta-cell line

L. Brennan, P. Newsholme, P. Flatt, 2003, Diabetologia.

NMR and Alanine Scan Studies of Glucose-dependent Insulinotropic Polypeptide in Water*

P. Flatt, J. Malthouse, J. Parker, 2006, Journal of Biological Chemistry.

A nuclear magnetic resonance-based demonstration of substantial oxidative L-alanine metabolism and L-alanine-enhanced glucose metabolism in a clonal pancreatic beta-cell line: metabolism of L-alanine is important to the regulation of insulin secretion.

L. Brennan, K. Brindle, P. Newsholme, 2002, Diabetes.

Prolonged L-alanine exposure induces changes in metabolism, Ca(2+) handling and desensitization of insulin secretion in clonal pancreatic beta-cells.

L. Brennan, P. Newsholme, P. Flatt, 2009, Clinical science.

Mechanism of the binding of Z-L-tryptophan and Z-L-phenylalanine to thermolysin and stromelysin-1 in aqueous solutions.

J. Malthouse, N. Howe, M. Ceruso, 2012, Biochimica et biophysica acta.

Quantifying tetrahedral adduct formation and stabilization in the cysteine and the serine proteases

J. Malthouse, P. Evans, J. A. Cleary, 2015, Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics.

A 13C-NMR study of azacryptand complexes.

J. Malthouse, G. G. Morgan, C. Hewage, 2014, Dalton transactions.

Biotransformation of halophenols using crude cell extracts of Pseudomonas putida F6

W. Duetz, K. E. O’ Connor, J. Malthouse, 2004, Applied Microbiology and Biotechnology.

Stereospecificity of alpha-proton exchange reactions catalysed by pyridoxal-5'-phosphate-dependent enzymes.

J. Malthouse, 2003, Biochimica et biophysica acta.

Investigation of the effects of sulfonylurea exposure on pancreatic beta cell metabolism

L. Brennan, P. Newsholme, P. Flatt, 2006, The FEBS journal.

Conformational, receptor interaction and alanine scan studies of glucose-dependent insulinotropic polypeptide.

J. Malthouse, F. O'Harte, C. Hewage, 2011, Biochimica et biophysica acta.

pH stability of the stromelysin-1 catalytic domain and its mechanism of interaction with a glyoxal inhibitor.

J. Malthouse, N. Howe, M. Ceruso, 2011, Biochimica et biophysica acta.

Kinetic Studies of the Effect of pH on the Trypsin-Catalyzed Hydrolysis of N-α-benzyloxycarbonyl-l-lysine-p-nitroanilide: Mechanism of Trypsin Catalysis

J. Malthouse, 2020, ACS omega.

Importance of tetrahedral intermediate formation in the catalytic mechanism of the serine proteases chymotrypsin and subtilisin.

J. Malthouse, N. Howe, Teodolinda Petrillo, 2012, Biochemistry.

Oxyanion and tetrahedral intermediate stabilisation by subtilisin: detection of a new tetrahedral adduct.

J. Malthouse, N. Howe, C. Hewage, 2009, Biochimica et biophysica acta.

13C- and 1H-NMR studies of oxyanion and tetrahedral intermediate stabilization by the serine proteinases: optimizing inhibitor warhead specificity and potency by studying the inhibition of the serine proteinases by peptide-derived chloromethane and glyoxal inhibitors.

J. Malthouse, 2007, Biochemical Society transactions.

13C and 1H NMR Studies of Ionizations and Hydrogen Bonding in Chymotrypsin-Glyoxal Inhibitor Complexes*

J. Malthouse, Edward Spink, C. Hewage, 2007, Journal of Biological Chemistry.

Ionisations within a subtilisin-glyoxal inhibitor complex.

J. Malthouse, C. Hewage, Aleksandra Djurdjevic-Pahl, 2005, Biochimica et biophysica acta.

Crystal structure of δ-chymotrypsin bound to a peptidyl chloromethyl ketone inhibitor

Walsh, J. Malthouse, A. M. Sweeney, 2000 .

A new lysine derived glyoxal inhibitor of trypsin, its properties and utilization for studying the stabilization of tetrahedral adducts by trypsin

J. Malthouse, J. A. Cleary, J. P. Malthouse, 2016, Biochemistry and biophysics reports.

NMR structure of the glucose-dependent insulinotropic polypeptide fragment, GIP(1-30)amide.

J. Malthouse, J. Parker, V. Gault, 2004, Biochemical and biophysical research communications.

The bioactive conformation of glucose‐dependent insulinotropic polypeptide by NMR and CD spectroscopy

J. Malthouse, C. Hewage, F. O'Harte, 2007, Proteins.

Determination of the structure of tetrahedral transition state analogues bound at the active site of chymotrypsin using 18O and 2H isotope shifts in the 13C NMR spectra of glyoxal inhibitors.

J. Malthouse, Edward Spink, C. Hewage, 2007, Biochemistry.

NMR study of the inhibition of pepsin by glyoxal inhibitors: mechanism of tetrahedral intermediate stabilization by the aspartyl proteases.

J. Malthouse, C. Hewage, Sonya Cosgrove, 2007, Biochemistry.

A 13C-NMR study of the role of Asn-155 in stabilizing the oxyanion of a subtilisin tetrahedral adduct.

R. Day, W. Bachovchin, J. Malthouse, 1997, The Biochemical journal.

13C-NMR study of the inhibition of delta-chymotrypsin by a tripeptide-glyoxal inhibitor.

J. Malthouse, C. Hewage, Aleksandra Djurdjevic-Pahl, 2002, The Biochemical journal.

An NMR study of alterations in [1- 13 C ]glucose metabolism in C6 glioma cells by gliotoxic amino acids

L. Brennan, J. Malthouse, G. McBean, 2003, Neurochemistry International.