G. Pan

发表

Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress.

B. Faubert, Russell G. Jones, S. Berger, 2011, Genes & development.

Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivo.

W. Cavenee, M. Nagane, H. Huang, 2000, Cancer research.

Discovery of inhibitors of the mitotic kinase TTK based on N-(3-(3-sulfamoylphenyl)-1H-indazol-5-yl)-acetamides and carboxamides.

Narendra Kumar Patel, T. Mak, N. Chirgadze, 2014, Bioorganic & medicinal chemistry.

The discovery of Polo-like kinase 4 inhibitors: design and optimization of spiro[cyclopropane-1,3'[3H]indol]-2'(1'H).ones as orally bioavailable antitumor agents.

Narendra Kumar Patel, T. Mak, N. Chirgadze, 2015 .

TRAIL (Apo-2L) and TRAIL receptors in human placentas: implications for immune privilege.

S. Ruben, J. S. Hunt, G. Pan, 1999, Journal of immunology.

Angelicin inhibits liver cancer growth in vitro and in vivo

G. Pan, Qiang Huang, Jun Li, 2017, Molecular medicine reports.

The discovery of PLK4 inhibitors: (E)-3-((1H-Indazol-6-yl)methylene)indolin-2-ones as novel antiproliferative agents.

Y. Liu, T. Mak, P. Sampson, 2013, Journal of medicinal chemistry.

The discovery of Polo-like kinase 4 inhibitors: design and optimization of spiro[cyclopropane-1,3'[3H]indol]-2'(1'H).ones as orally bioavailable antitumor agents.

Narendra Kumar Patel, Y. Liu, T. Mak, 2015, Journal of medicinal chemistry.

in Vivo and in Vitro Ligand with Tumor Necrosis Factor-related Apoptosis-inducing Agents in Human Gliomas Causes Synergistic Cytotoxicity Increased Death Receptor 5 Expression by Chemotherapeutic

W. Cavenee, M. Nagane, H. Huang, 2000 .

Advances in Brief Increased Death Receptor 5 Expression by Chemotherapeutic Agents in Human Gliomas Causes Synergistic Cytotoxicity with Tumor Necrosis Factor-related Apoptosis-inducing Ligand in Vitro and in Vivo

W. Cavenee, M. Nagane, H. Huang, 2000 .

The Receptor for the Cytotoxic Ligand TRAIL

Arul M. Chinnaiyan, Karen O'Rourke, Vishva M. Dixit, 1997, Science.

An antagonist decoy receptor and a death domain-containing receptor for TRAIL.

R. Gentz, V. Dixit, Guo-liang Yu, 1997, Science.

Knock-Out of the Neural Death Effector Domain Protein PEA-15 Demonstrates That Its Expression Protects Astrocytes from TNFα-Induced Apoptosis

J. Glowinski, E. Formstecher, H. Chneiweiss, 1999, The Journal of Neuroscience.

Identification and functional characterization of DR6, a novel death domain‐containing TNF receptor

B. Aggarwal, V. Dixit, Guo-liang Yu, 1998, FEBS letters.

Caspase-9, Bcl-XL, and Apaf-1 Form a Ternary Complex*

V. Dixit, K. O'rourke, G. Pan, 1998, The Journal of Biological Chemistry.

The discovery of Polo-like kinase 4 inhibitors: design and optimization of spiro[cyclopropane-1,3'[3H]indol]-2'(1'H).ones as orally bioavailable antitumor agents.

Narendra Kumar Patel, Y. Liu, T. Mak, 2015, Journal of medicinal chemistry.

Targeting HER2+ breast cancer cells: lysosomal accumulation of anti-HER2 antibodies is influenced by antibody binding site and conjugation to polymeric nanoparticles.

J. Moffat, M. Shoichet, S. Sidhu, 2013, Journal of controlled release : official journal of the Controlled Release Society.

Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies

J. Moffat, S. Angers, J. Julien, 2019, Proceedings of the National Academy of Sciences.

Functional characterization of CFI-400945, a Polo-like kinase 4 inhibitor, as a potential anticancer agent.

D. Cescon, T. Mak, D. Awrey, 2014, Cancer cell.

TRUNDD, a new member of the TRAIL receptor family that antagonizes TRAIL signalling

V. Dixit, Guo-liang Yu, Jian Ni, 1998, FEBS letters.

Design and optimization of (3-aryl-1H-indazol-6-yl)spiro[cyclopropane-1,3'-indolin]-2'-ones as potent PLK4 inhibitors with oral antitumor efficacy.

Narendra Kumar Patel, T. Mak, P. Sampson, 2016, Bioorganic & medicinal chemistry letters.

TRAIL ( Apo-2 L ) and TRAIL Receptors in Human Placentas : Implications for Immune Privilege 1

S. Ruben, J. S. Hunt, G. Pan, 1999 .

γ-Synuclein Is an Adipocyte-Neuron Gene Coordinately Expressed with Leptin and Increased in Human Obesity

K. Clément, V. Buchman, S. Adams, 2008, The Journal of nutrition.

Corrigendum to: Activation of caspases triggered by cytochrome c in vitro (FEBS 20097)

V. Dixit, E. Humke, G. Pan, 1998 .

Synthetic Antibodies with a Human Framework That Protect Mice from Lethal Sudan Ebolavirus Challenge

Samantha E. Zak, J. Dye, K. Chandran, 2014, ACS chemical biology.

The discovery of Polo-like kinase 4 inhibitors: identification of (1R,2S).2-(3-((E).4-(((cis).2,6-dimethylmorpholino)methyl)styryl). 1H.indazol-6-yl)-5'-methoxyspiro[cyclopropane-1,3'-indolin]-2'-one (CFI-400945) as a potent, orally active antitumor agent.

Narendra Kumar Patel, Y. Liu, T. Mak, 2015, Journal of medicinal chemistry.