Lauren M Thorpe

PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting

Jean J. Zhao, Haluk Yuzugullu, Lauren M Thorpe, 2014, Nature Reviews Cancer.

Significant and durable clinical benefit from trastuzumab in 2 patients with HER2‐amplified salivary gland cancer and a review of the literature

V. Miller, R. Erlich, Siraj M. Ali, 2017, Head & neck.

PI3K-p110α mediates the oncogenic activity induced by loss of the novel tumor suppressor PI3K-p85α

L. Cantley, J. Spangle, Hailing Cheng, 2017, Proceedings of the National Academy of Sciences.

PI3K regulatory subunit p85alpha plays a tumor suppressive role in the transformation of mammary epithelial cells

Lauren M Thorpe, 2015 .

NTRK2 activation cooperates with PTEN deficiency in T-ALL through activation of both the PI3K–AKT and JAK–STAT3 pathways

T. Roberts, Jean J. Zhao, D. Frank, 2016, Cell Discovery.

NTRK 2 activation cooperates with PTEN de fi ciency in TALL through activation of both the PI 3 K – AKT and JAK – STAT 3 pathways

T. Roberts, Jean J. Zhao, D. Frank, 2016 .

Apical constriction and invagination downstream of the canonical Wnt signaling pathway require Rho1 and Myosin II.

Lauren M Thorpe, B. McCartney, Sandra G Zimmerman, 2010, Developmental biology.