Xiaofei Chen

发表

Metabolomic study of the protective effect of Gandi capsule for diabetic nephropathy.

Y. Chai, Zhenyu Zhu, Yue Liu, 2019, Chemico-biological interactions.

In situ synthesis and unidirectional insertion of membrane proteins in liposome-immobilized silica stationary phase for rapid preparation of microaffinity chromatography

Z. Hong, Y. Chai, Zhenyu Zhu, 2022, Acta pharmaceutica Sinica. B.

The Bcr-Abl inhibitor GNF-7 inhibits necroptosis and ameliorates acute kidney injury by targeting RIPK1 and RIPK3 kinases.

Hongyang Wang, Xiufeng Pang, Xiaofei Chen, 2020, Biochemical pharmacology.

N-(7-Cyano-6-(4-fluoro-3-(2-(3-(trifluoromethyl)phenyl)acetamido)phenoxy)benzo[ d]thiazol-2-yl)cyclopropanecarboxamide (TAK-632) Analogues as Novel Necroptosis Inhibitors by Targeting Receptor-Interacting Protein Kinase 3 (RIPK3): Synthesis, Structure-Activity Relationships, and in Vivo Efficacy.

Xiaofei Chen, Zhenyuan Miao, Wannian Zhang, 2019, Journal of medicinal chemistry.

Dynamic metabolic and transcriptomic profiling of methyl jasmonate‐treated hairy roots reveals synthetic characters and regulators of lignan biosynthesis in Isatis indigotica Fort

Wansheng Chen, Xin Dong, Xiaofei Chen, 2016, Plant biotechnology journal.

Comparative two-dimensional GPC3 overexpressing SK-Hep1 cell membrane chromatography /C18/ time-of-flight mass spectrometry for screening selective GPC3 inhibitor components from Scutellariae Radix.

Zhenyu Zhu, Xiaofei Chen, Yongfang Yuan, 2020, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Progress of Cell Membrane Chromatography and Its Application in Screening Active Ingredients of Traditional Chinese Medicine

Z. Hong, Y. Chai, Xiaofei Chen, 2018, Chinese Journal of Analytical Chemistry.

Covalent Design of Cell Membrane Stationary Phase with Enhanced Stability for Fast Screening P-Glycoprotein Inhibitors

W. Xiaoyu, Z. Hong, Yue Liu, 2020 .

A method for screening active components from Chinese herbs by cell membrane chromatography-offline-high performance liquid chromatography/mass spectrometry and an online statistical tool for data processing.

Zhenyu Zhu, Xiaofei Chen, Yongfang Yuan, 2018, Journal of chromatography. A.

Quality improvements of cell membrane chromatographic column.

Xuan Ding, Z. Hong, Y. Chai, 2014, Journal of chromatography. A.

On-line comprehensive two-dimensional HepG2 cell membrane chromatographic analysis system for charactering anti-hepatoma components from rat serum after oral administration of Radix scutellariae: A strategy for rapid screening active compounds in vivo.

Xuan Ding, Y. Chai, Zhenyu Zhu, 2016, Journal of pharmaceutical and biomedical analysis.

Identification of multiple components in Guanxinning injection using hydrophilic interaction liquid chromatography/time-of-flight mass spectrometry and reversed-phase liquid chromatography/time-of-flight mass spectrometry.

Z. Lou, Y. Chai, Zhenyu Zhu, 2011, Rapid communications in mass spectrometry : RCM.

Combination of comprehensive two-dimensional prostate cancer cell membrane chromatographic system and network pharmacology for characterizing membrane binding active components from Radix et Rhizoma Rhei and their targets.

Xuan Ding, Y. Chai, Zhenyu Zhu, 2018, Journal of chromatography. A.

Revealing Synergistic Mechanism of Multiple Components in Gandi Capsule for Diabetic Nephropathy Therapeutics by Network Pharmacology

A. Dahan, Y. Chai, Xiaofei Chen, 2018, Evidence-based complementary and alternative medicine : eCAM.

Neobavaisoflavone inhibits osteoclastogenesis through blocking RANKL signalling‐mediated TRAF6 and c‐Src recruitment and NF‐κB, MAPK and Akt pathways

Jiacan Su, Xiaofei Chen, Liehu Cao, 2020, Journal of cellular and molecular medicine.

Elucidation of steroid glycosides in Anemarrhena asphodeloides extract by means of comprehensive two-dimensional reversed-phase/polyamine chromatography with mass spectrometric detection.

Y. Qi, Y. Chai, Zhenyu Zhu, 2012, Journal of separation science.

Cardioprotective mechanism study of salvianic acid A sodium based on a proteome microarray approach and metabolomic profiling of rat serum after myocardial infarction.

Y. Chai, Zhenyu Zhu, Xiaofei Chen, 2019, Molecular omics.

Characterization of Nucleotides and Nucleotide Sugars in Candida albicans by High Performance Liquid Chromatography–Mass Spectrometry with a Porous Graphite Carbon Column

Z. Lou, Y. Chai, Zhenyu Zhu, 2014 .

UPLC-Q-TOF/MS based metabolomic profiling of serum and urine of hyperlipidemic rats induced by high fat diet

Xin Dong, Z. Hong, Y. Chai, 2014, Journal of pharmaceutical analysis.

Analysis methods of amino acids and small peptides from microorganism: recent advance: Analysis methods of amino acids and small peptides from microorganism: recent advance

Zhenyu Zhu, Xiaofei Chen, Ying-ying Cao, 2012 .

Rapid on-site detection of ephedrine and its analogues used as adulterants in slimming dietary supplements by TLC-SERS

Z. Lou, Feng Lu, Y. Chai, 2015, Analytical and Bioanalytical Chemistry.

Identification of the Raf kinase inhibitor TAK‐632 and its analogues as potent inhibitors of necroptosis by targeting RIPK1 and RIPK3

Hong-Yang Wang, Y. Chai, Xiaofei Chen, 2019, British journal of pharmacology.

Identifying potential anti-COVID-19 pharmacological components of traditional Chinese medicine Lianhuaqingwen capsule based on human exposure and ACE2 biochromatography screening

Mingshe Zhu, Yunlong Wu, Caisheng Wu, 2020, Acta Pharmaceutica Sinica B.

A stop-flow comprehensive two-dimensional HK-2 and HK-2/CIKI cell membrane chromatography comparative analysis system for screening the active ingredients from Pyrrosia calvata (Bak.) Ching against crystal-induced kidney injury.

Zhiyong Guo, Wei Chen, Z. Hong, 2020, Journal of pharmaceutical and biomedical analysis.

Nuclear magnetic resonance-based plasma metabolomics revealed the protective effect of tea polyphenols on sulfur mustard-induced injury in rats.

Z. Hong, Y. Chai, Zhenyu Zhu, 2020, Journal of pharmaceutical and biomedical analysis.

Targeting actin-bundling protein L-plastin as an anabolic therapy for bone loss

Jiacan Su, Xiaofei Chen, Liehu Cao, 2020, Science Advances.

The multitargeted kinase inhibitor KW-2449 ameliorates cisplatin-induced nephrotoxicity by targeting RIPK1-mediated necroptosis.

Hong-Yang Wang, Jianqiang Yu, Xiaofei Chen, 2021, Biochemical pharmacology.

A novel strategy of profiling the mechanism of herbal medicines by combining network pharmacology with plasma concentration determination and affinity constant measurement.

Y. Chai, Zhenyu Zhu, Xiaofei Chen, 2016, Molecular bioSystems.

Guaiacol suppresses osteoclastogenesis by blocking interactions of RANK with TRAF6 and C‐Src and inhibiting NF‐κB, MAPK and AKT pathways

Jiacan Su, Xiaofei Chen, Liehu Cao, 2020, Journal of cellular and molecular medicine.

Construction of a novel blood brain barrier-glioma microfluidic chip model: Applications in the evaluation of permeability and anti-glioma activity of traditional Chinese medicine components.

Z. Hong, Y. Chai, Xiaofei Chen, 2022, Talanta.

Gandi Capsule Improved Podocyte Lipid Metabolism of Diabetic Nephropathy Mice through SIRT1/AMPK/HNF4A Pathway

Yan Liu, Yue Liu, Xiaofei Chen, 2022, Oxidative medicine and cellular longevity.

Label-free target protein characterization for small molecule drugs: recent advances in methods and applications.

Y. Chai, Xiaofei Chen, Weiyue Zhang, 2022, Journal of pharmaceutical and biomedical analysis.

Effect of amphotericin B on the metabolic profiles of Candida albicans.

Y. Chai, Zhenyu Zhu, Lan Yan, 2013, Journal of proteome research.

Comparative two‐dimensional HepG2 and L02/ cell membrane chromatography/ C18/ time‐of‐flight mass spectrometry for screening selective anti‐hepatoma components from Scutellariae Radix

Y. Chai, Zhenyu Zhu, Xiaofei Chen, 2019, Journal of pharmaceutical and biomedical analysis.

Comparative pharmacokinetics of timosaponin B-II and timosaponin A-III after oral administration of Zhimu-Baihe herb-pair, Zhimu extract, free timosaponin B-II and free timosaponin A-III to rats.

Yueyue Li, Xuan Ding, Xin Dong, 2013, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Novel transketolase inhibitor oroxylin A suppresses the non‐oxidative pentose phosphate pathway and hepatocellular carcinoma tumour growth in mice and patient‐derived organoids

Hong-Yang Wang, W. Wen, Z. Hong, 2022, Clinical and translational medicine.

Enantioseparation of new triadimenol antifungal active compounds by electrokinetic chromatography and molecular modeling study of chiral recognition mechanisms

Liang Zhao, Z. Hong, Y. Chai, 2014, Electrophoresis.

Computer-aided molecular modeling study of enantioseparation of iodiconazole and structurally related triadimenol analogues by capillary electrophoresis: chiral recognition mechanism and mathematical model for predicting chiral separation.

Y. Chai, Zhenyu Zhu, Xiaofei Chen, 2012, Analytica chimica acta.

Liquid chromatography coupled with time-of-flight and ion trap mass spectrometry for qualitative analysis of herbal medicines

Hai Wu, Y. Chai, Zhenyu Zhu, 2011, Journal of pharmaceutical analysis.

Analysis and pharmacokinetic study of curdione in Rhizoma Curcumae by UPLC/QTOF/MS.

Z. Lou, Xin Dong, Y. Chai, 2014, Biomedical chromatography : BMC.

Activity ranking of synthetic analogs targeting vascular endothelial growth factor receptor 2 by an integrated cell membrane chromatography system.

Xuan Ding, Y. Chai, Zhenyu Zhu, 2015, Journal of separation science.

Salvianic acid A sodium protects HUVEC cells against tert-butyl hydroperoxide induced oxidative injury via mitochondria-dependent pathway.

Xuan Ding, Y. Chai, Zhenyu Zhu, 2018, Chemico-biological interactions.

Ion-pairing chromatography on a porous graphitic carbon column coupled with time-of-flight mass spectrometry for targeted and untargeted profiling of amino acid biomarkers involved in Candida albicans biofilm formation.

Liang Zhao, Y. Chai, Zhenyu Zhu, 2014, Molecular bioSystems.

Cardioprotective mechanisms of salvianic acid A sodium in rats with myocardial infarction based on proteome and transcriptome analysis

C. Zhang, Zhenyu Zhu, Xiaofei Chen, 2019, Acta Pharmacologica Sinica.

Development of APTES-Decorated HepG2 Cancer Stem Cell Membrane Chromatography for Screening Active Components from Salvia miltiorrhiza.

Xuan Ding, Guoqing Zhang, Z. Hong, 2016, Analytical chemistry.

Comparative Normal/Failing Rat Myocardium Cell Membrane Chromatographic Analysis System for Screening Specific Components That Counteract Doxorubicin-Induced Heart Failure from Acontium carmichaeli

Zhanying Hong, Yifeng Chai, Xiang-Qun Xie, 2014, Analytical chemistry.

Comprehensive two-dimensional HepG2/cell membrane chromatography/monolithic column/time-of-flight mass spectrometry system for screening anti-tumor components from herbal medicines.

Yifeng Chai, Diya Lv, Yan Cao, 2012, Journal of chromatography. A.

A distinct glycerophospholipid metabolism signature of acute graft versus host disease with predictive value.

Jianmin Yang, Z. Hong, Y. Chai, 2019, JCI insight.

NMR and LC/MS‐based global metabolomics to identify serum biomarkers differentiating hepatocellular carcinoma from liver cirrhosis

Z. Lou, Xin Dong, Guoqing Zhang, 2014, International journal of cancer.

Assessment of the hemolysis and endothelial cell cytotoxicity induced by residual linear alkylbenzene sulfonates on pharmaceutical rubber stoppers based on HPLC-ESI-MS.

Yueyue Li, Y. Chai, Zhenyu Zhu, 2015, Biomedical chromatography : BMC.

Cell-free protein synthesis system for bioanalysis: Advances in methods and applications

Y. Chai, Yue Liu, Xiaofei Chen, 2023, TrAC Trends in Analytical Chemistry.

Identification of a ligand for tumor necrosis factor receptor from Chinese herbs by combination of surface plasmon resonance biosensor and UPLC-MS

Yan Cao, Y. Chai, Xiaofei Chen, 2016, Analytical and Bioanalytical Chemistry.

Biosensor-Based Active Ingredients Recognition System for Screening STAT3 Ligands from Medical Herbs.

Jianmin Yang, Z. Hong, Y. Chai, 2018, Analytical chemistry.

Shenjinhuoxue Mixture Attenuates Inflammation, Pain, and Cartilage Degeneration by Inhibiting TLR-4 and NF-κB Activation in Rats with Osteoarthritis: A Synergistic Combination of Multitarget Active Phytochemicals

Xiaofei Chen, Zhaokang Zhang, Xiaoqin Ma, 2021, Oxidative medicine and cellular longevity.

Investigation of the therapeutic effectiveness of active components in Sini decoction by a comprehensive GC/LC-MS based metabolomics and network pharmacology approaches.

Zhanying Hong, Yifeng Chai, Xin Dong, 2014, Molecular bioSystems.

Cardiovascular Disease Chemogenomics Knowledgebase-guided Target Identification and Drug Synergy Mechanism Study of an Herbal Formula

Yifeng Chai, Zhiwei Feng, Shifan Ma, 2016, Scientific Reports.

Screening potential P-glycoprotein inhibitors by combination of a detergent-free membrane protein extraction with surface plasmon resonance biosensor

Z. Hong, Y. Chai, Yue Liu, 2022, Acta pharmaceutica Sinica. B.

Target Identification of Kinase Inhibitor Alisertib (MLN8237) by Using DNA-Programmed Affinity Labeling.

Yan Cao, Xiaoyu Li, Z. Hong, 2017, Chemistry.

Using cell membrane chromatography and HPLC-TOF/MS method for in vivo study of active components from roots of Aconitum carmichaeli

Xin Dong, Y. Chai, Xiaofei Chen, 2011, Journal of pharmaceutical analysis.

Qualitative and quantitative analysis of Fructus Corni using ultrasound assisted microwave extraction and high performance liquid chromatography coupled with diode array UV detection and time-of-flight mass spectrometry.

Y. Chai, Zhenyu Zhu, Xiaofei Chen, 2011, Journal of pharmaceutical and biomedical analysis.

Methodology of drug screening and target identification for new necroptosis inhibitors

Y. Chai, Xiaofei Chen, Zhenyu Cai, 2018, Journal of pharmaceutical analysis.

Identification of eupatilin and ginkgolide B as p38 ligands from medicinal herbs by surface plasmon resonance biosensor-based active ingredients recognition system.

Z. Hong, Y. Chai, Yue Liu, 2019, Journal of pharmaceutical and biomedical analysis.

4‐phenylbutyric acid promotes hepatocellular carcinoma via initiating cancer stem cells through activation of PPAR‐α

Hongyang Wang, S. Monga, W. Wen, 2021, Clinical and translational medicine.

Comprehensive two-dimensional APTES-decorated MCF7-cell membrane chromatographic system for characterizing potential anti-breast-cancer components from Yuanhu–Baizhi herbal medicine pair

Xuan Ding, Z. Hong, Y. Chai, 2017, Journal of food and drug analysis.

Corrigendum: Characterization of anti-leukemia components from Indigo naturalis using comprehensive two-dimensional K562/cell membrane chromatography and in silico target identification

Y. Diao, P. Zerbe, Y. Chai, 2016, Scientific Reports.

Characterization of anti-leukemia components from Indigo naturalis using comprehensive two-dimensional K562/cell membrane chromatography and in silico target identification

Y. Diao, P. Zerbe, Y. Chai, 2016, Scientific Reports.

Development of 3-mercaptopropyltrimethoxysilane (MPTS)-modified bone marrow mononuclear cell membrane chromatography for screening anti-osteoporosis components from Scutellariae Radix

Jiacan Su, Y. Chai, Yue Liu, 2020, Acta pharmaceutica Sinica. B.

Integrated metabolomics and network pharmacology approach to exploring the potential mechanism of Tianxiang Capsule for treating motion sickness.

Yue Liu, Xiaofei Chen, Feng Li, 2021, Journal of ethnopharmacology.

Simulation Strategies for Characterizing Phosphodiesterase-5 Inhibitors in Botanical Dietary Supplements.

Feng Lu, Y. Chai, Xiaofei Chen, 2018, Analytical chemistry.

An SPR-based membrane protein-targeted active ingredients recognition strategy: construction and implementation in ligand screening from herbal medicines.

Z. Hong, Y. Chai, Zhenyu Zhu, 2020, Analytical chemistry.

Screening of immune cell activators from Astragali Radix using a comprehensive two-dimensional NK-92MI cell membrane chromatography/C18 column/time-of-flight mass spectrometry system

Z. Hong, Y. Chai, Zhenyu Zhu, 2022, Journal of pharmaceutical analysis.

Revealing Synergistic Mechanism of Multiple Components in Gandi Capsule for Diabetic Nephropathy Therapeutics by Network Pharmacology

A. Dahan, Y. Chai, Xiaofei Chen, 2018, Evidence-based complementary and alternative medicine : eCAM.

Development of a surface plasmon resonance biosensor for accurate and sensitive quantitation of small molecules in blood samples

Z. Hong, Y. Chai, Zhenyu Zhu, 2022, Journal of pharmaceutical analysis.