K. Lim

发表

Global metabolomics and targeted steroid profiling reveal that rifampin, a strong human PXR activator, alters endogenous urinary steroid markers.

Joo-Youn Cho, K. Yu, I. Jang, 2013, Journal of proteome research.

Pharmacokinetic and Pharmacodynamic Interaction of Lorazepam and Valproic Acid in Relation to UGT2B7 Genetic Polymorphism in Healthy Subjects

I. Jang, K. Lim, J-Y Chung, 2008, Clinical pharmacology and therapeutics.

Comparison of the pharmacokinetics and tolerability of HCP1004 (a fixed-dose combination of naproxen and esomeprazole strontium) and VIMOVO® (a marketed fixed-dose combination of naproxen and esomeprazole magnesium) in healthy volunteers

K. Yu, K. Lim, Yoonjung Choi, 2015, Drug design, development and therapy.

Changes in the QTc interval after administration of flecainide acetate, with and without coadministered paroxetine, in relation to cytochrome P450 2D6 genotype: data from an open-label, two-period, single-sequence crossover study in healthy Korean male subjects.

Joo-Youn Cho, K. Yu, I. Jang, 2010, Clinical therapeutics.

Influence of alcohol on the hemodynamic effects and pharmacokinetic properties of mirodenafil: a single-dose, randomized-sequence, open-label, crossover study in healthy male volunteers in Korea.

K. Yu, I. Jang, Sang-Goo Shin, 2009, Clinical therapeutics.

Effect of the UGT2B15 Genotype on the Pharmacokinetics, Pharmacodynamics, and Drug Interactions of Intravenous Lorazepam in Healthy Volunteers

Joo-Youn Cho, K. Yu, Jae-Yong Chung, 2005, Clinical pharmacology and therapeutics.

Evaluation of Endogenous Metabolic Markers of Hepatic CYP3A Activity Using Metabolic Profiling and Midazolam Clearance

I. Jang, K. Lim, J. Cho, 2013, Clinical pharmacology and therapeutics.

A fixed-dose combination tablet of gemigliptin and metformin sustained release has comparable pharmacodynamic, pharmacokinetic, and tolerability profiles to separate tablets in healthy subjects

Sang-In Park, K. Yu, I. Jang, 2015, Drug design, development and therapy.

A Randomized, Placebo Controlled, Double Blind, Parallel Group, Multiple Dosing, Dose Escalation Clinical Study to Evaluate Pharmacokinetics/Pharmacodynamics and Tolerability of Zofenopril in Healthy Korean Subjects

K. Yu, Jae-Yong Chung, I. Jang, 2013 .

Increased Systemic Exposure of Fimasartan, an Angiotensin II Receptor Antagonist, by Ketoconazole and Rifampicin

Min Goo Lee, Joo-Youn Cho, K. Yu, 2013, Journal of clinical pharmacology.

Pharmacokinetic–Pharmacodynamic Relationships of Macitentan, a New Endothelin Receptor Antagonist, After Multiple Dosing in Healthy Korean Subjects

K. Yu, I. Jang, K. Lim, 2014, American Journal of Cardiovascular Drugs.

Pharmacokinetic Characteristics of Lafutidinein Healthy Subjects

Joo-Youn Cho, K. Yu, I. Jang, 2007 .

Evaluation of the pharmacokinetic and pharmacodynamic drug interactions between cilnidipine and valsartan, in healthy volunteers

K. Yu, K. Lim, Howard Lee, 2014, Drug design, development and therapy.

Pharmacokinetic-pharmacodynamic analysis to evaluate the effect of moxifloxacin on QT interval prolongation in healthy Korean male subjects

Jongtae Lee, D. Yim, K. Yu, 2015, Drug design, development and therapy.

Effects of HM30181, a P-glycoprotein inhibitor, on the pharmacokinetics and pharmacodynamics of loperamide in healthy volunteers.

Joo-Youn Cho, K. Yu, I. Jang, 2014, British journal of clinical pharmacology.

Pharmacokinetics, pharmacodynamics, and tolerability of the dipeptidyl peptidase IV inhibitor LC15-0444 in healthy Korean men: a dose-block-randomized, double-blind, placebo-controlled, ascending single-dose, Phase I study.

Joo-Youn Cho, K. Yu, Jung-Ryul Kim, 2008, Clinical therapeutics.

Pharmacokinetic interaction of flecainide and paroxetine in relation to the CYP2D6*10 allele in healthy Korean subjects.

Joo-Youn Cho, K. Yu, I. Jang, 2008, British journal of clinical pharmacology.

Pharmacokinetic and Pharmacodynamic Interaction Between Gemigliptin and Metformin in Healthy Subjects

Y. Cho, Joo-Youn Cho, K. Yu, 2014, Clinical Drug Investigation.

Effects of Angelicae tenuissima radix, Angelicae dahuricae radix and Scutellariae radix extracts on cytochrome P450 activities in healthy volunteers.

Joo-Youn Cho, K. Yu, I. Jang, 2009, Basic & clinical pharmacology & toxicology.

Effects of Pregnane X Receptor (NR1I2) and CYP2B6 Genetic Polymorphisms on the Induction of Bupropion Hydroxylation by Rifampin

Joo-Youn Cho, K. Yu, Jae-Yong Chung, 2011, Drug Metabolism and Disposition.

Evaluation of Pharmacokinetics and Tolerability of Eplerenone after Multiple Oral Doses of 100 mg in Healthy Korean Volunteers

D. Oh, K. Yu, I. Jang, 2011 .

Sustained Increase in the Oral Bioavailability of Loperamide after a Single Oral Dose of HM30181, a P‐glycoprotein Inhibitor, in Healthy Male Participants

Joo-Youn Cho, K. Yu, Jae-Yong Chung, 2013, Basic & clinical pharmacology & toxicology.

Pharmacokinetics and Tolerability Evaluation of Human Coagulation Recombinant Factor VIII (GreenGene^TM) in Hemophilia A Patients

Joo-Youn Cho, K. Yu, Jae-Yong Chung, 2011 .

The effect of udenafil on the hemodynamics of healthy male volunteers administered tamsulosin

Joo-Youn Cho, K. Yu, Jung-Ryul Kim, 2013, Current medical research and opinion.

The effect of fimasartan, an angiotensin receptor type 1 blocker, on the pharmacokinetics and pharmacodynamics of warfarin in healthy Korean male volunteers: a one-sequence, two-period crossover clinical trial.

Joo-Youn Cho, K. Yu, I. Jang, 2012, Clinical therapeutics.

Pharmacokinetics and Tolerability Evaluation of Fudosteine after Oral Administration in Healthy Korean Volunteers

Joo-Youn Cho, K. Yu, Jae-Yong Chung, 2011 .

Population Pharmacokinetics of Theophylline in Premature Korean Infants

Joo-Youn Cho, K. Yu, I. Jang, 2013, Therapeutic drug monitoring.

Population Pharmacokinetics of Vancomycin in Korean Pediatric Patients

K. Yu, Jung-Ryul Kim, I. Jang, 2008 .

Pharmacokinetics of T-614 after Single Oral Administration in Healthy Korean Volunteers

K. Yu, Jung-Ryul Kim, I. Jang, 2013 .

Pharmacokinetic–Pharmacodynamic Modelling of Biomarker Response to Sitagliptin in Healthy Volunteers

Joo-Youn Cho, K. Yu, Jung-Ryul Kim, 2013, Basic & clinical pharmacology & toxicology.

First-in-human, double-blind, randomized controlled trial of an oral dose of GnRH antagonist, TU2670 in healthy women.

Hun-Taek Kim, Sang-Heon Cho, Yong-Soon Cho, 2020, The Journal of clinical endocrinology and metabolism.

Comparison of Pharmacokinetics and Safety Between Coadministration of Cilostazol and Ginkgo Biloba Extract and Administration of a Fixed-Dose Combination

K. Yu, I. Jang, K. Lim, 2010 .

Pharmacokinetic and Pharmacodynamic Properties of a New Long-Acting Granulocyte Colony-Stimulating Factor (HM10460A) in Healthy Volunteers

Joo-Youn Cho, K. Yu, I. Jang, 2013, BioDrugs.

Relationship Between Absolute Neutrophil Count Profiles and Pharmacokinetics of DA-3031, a Pegylated Granulocyte Colony-Stimulating Factor (Pegylated-G-CSF): A Dose Block-Randomized, Double-Blind, Dose-Escalation Study in Healthy Subjects

Joo-Youn Cho, K. Yu, I. Jang, 2013, Clinical Drug Investigation.

Safety, tolerability and pharmacokinetics of udenafil, a novel PDE-5 inhibitor, in healthy young Korean subjects.

Joo-Youn Cho, K. Yu, Jae-Yong Chung, 2008, British journal of clinical pharmacology.

Post lumbar puncture headache: Case report of a serious adverse event in first-in-human study

Jinkwon Kim, K. Lim, Min-Kyoung Kim, 2017, Translational and clinical pharmacology.

An assessment of the pharmacokinetics, pharmacodynamics, and tolerability of GCPGC, a novel pegylated granulocyte colony-stimulating factor (G-CSF), in healthy subjects

K. Yu, I. Jang, K. Lim, 2014, Investigational new drugs.

Tolerability and Pharmacokinetics Following a Single Dose of Vardenafil in Healthy Korean Volunteers

K. Yu, Hyeong-Seok Lim, I. Jang, 2012 .

Novel nanocrystal formulation of megestrol acetate has improved bioavailability compared with the conventional micronized formulation in the fasting state

Joo-Youn Cho, K. Yu, I. Jang, 2014, Drug design, development and therapy.

Evaluation of the pharmacokinetics, food effect, pharmacodynamics, and tolerability of DA-1229, a dipeptidyl peptidase IV inhibitor, in healthy volunteers: first-in-human study.

Joo-Youn Cho, K. Yu, I. Jang, 2012, Clinical therapeutics.

Quantification of Human Plasma-Busulfan Concentration by Liquid Chromatography-Tandem Mass Spectrometry

Ji Won Lee, K. Yu, S. Song, 2013, Annals of laboratory medicine.

Pharmacokinetic and pharmacodynamic properties of the calcimimetic agent cinacalcet (KRN1493) in healthy male Korean subjects: a randomized, open-label, single ascending-dose, parallel-group study.

K. Yu, I. Jang, K. Lim, 2012, Clinical therapeutics.

Influence of Ginkgo biloba extract on the pharmacodynamic effects and pharmacokinetic properties of ticlopidine: an open-label, randomized, two-period, two-treatment, two-sequence, single-dose crossover study in healthy Korean male volunteers.

Joo-Youn Cho, K. Yu, Jung-Ryul Kim, 2010, Clinical therapeutics.

Reduced Valproic Acid Serum Concentrations Due to Drug Interactions With Carbapenem Antibiotics: Overview of 6 Cases

Joo-Youn Cho, K. Yu, I. Jang, 2012, Therapeutic drug monitoring.

Genetic Polymorphisms of the Carboxylesterase 1 (CES1) Gene in a Korean Population

Eun-Young Kim, Joo-Youn Cho, K. Yu, 2014 .

Korean, Japanese, and Chinese populations featured similar genes encoding drug-metabolizing enzymes and transporters: a DMET Plus microarray assessment

Youngjo Lee, Y. Sugiyama, Joo-Youn Cho, 2014, Pharmacogenetics and genomics.

A Placebo-Controlled, Single and Multiple Dose Study to Investigate the Appropriate Parameters for Evaluation of Pharmacodynamic Equivalence of Voglibose in Healthy Korean Volunteers

Sang-Heon Cho, K. Yu, I. Jang, 2013 .

Effect of OATP1B1 (SLCO1B1) variant alleles on the pharmacokinetics of pitavastatin in healthy volunteers

D. Oh, Joo-Youn Cho, K. Yu, 2005, Clinical pharmacology and therapeutics.

Trough Concentration Over 12.1 mg/L is a Major Risk Factor of Vancomycin-Related Nephrotoxicity in Patients With Therapeutic Drug Monitoring

Ju Han Kim, Sang-Heon Cho, Hye‐Ryun Kang, 2014, Therapeutic drug monitoring.

Comparative Pharmacokinetics/Pharmacodynamics of Clopidogrel Besylate and Clopidogrel Bisulfate in Healthy Korean Subjects

Joo-Youn Cho, K. Yu, Jung-Ryul Kim, 2012, Clinical Drug Investigation.

Effect of intranasal esketamine on cognitive functioning in healthy participants: a randomized, double-blind, placebo-controlled study

W. Drevets, J. V. van Gerven, Jaskaran Singh, 2016, Psychopharmacology.

Pharmacokinetics and pharmacodynamics of LC15-0444, a novel dipeptidyl peptidase IV inhibitor, after multiple dosing in healthy volunteers.

Joo-Youn Cho, K. Yu, Jung-Ryul Kim, 2009, British journal of clinical pharmacology.

Pharmacodynamics, Pharmacokinetics, and Tolerability of Intravenous or Subcutaneous GC1113, a Novel Erythropoiesis-Stimulating Agent

Jongtae Lee, Joo-Youn Cho, K. Yu, 2014, Clinical Drug Investigation.

Assessment of the effect of mirodenafil on the hemodynamics of healthy male Korean volunteers administered tamsulosin: a randomized, double-blind, placebo-controlled, 2-period crossover study.

K. Yu, I. Jang, K. Lim, 2012, Clinical therapeutics.

Assessment of the Drug–Drug Interactions Between Fimasartan and Hydrochlorothiazide in Healthy Volunteers

Joo-Youn Cho, K. Yu, I. Jang, 2012, Journal of cardiovascular pharmacology.

Pharmacokinetic and Pharmacodynamic Properties of a New Long-Acting Granulocyte Colony-Stimulating Factor (HM10460A) in Healthy Volunteers

Joo-Youn Cho, K. Yu, I. Jang, 2013, BioDrugs.

A thorough QT study to evaluate the QTc prolongation potential of two neuropsychiatric drugs, quetiapine and escitalopram, in healthy volunteers

Joo-Youn Cho, K. Yu, I. Jang, 2016, International clinical psychopharmacology.

Influence of Simvastatin on Pharmacokinetics/Pharmacodynamics of Aspirin after Oral Co-administration in Healthy Volunteers

D. Yim, K. Yu, I. Jang, 2011 .

Comparative Pharmacokinetics of HD203, a Biosimilar of Etanercept, with Marketed Etanercept (Enbrel ®)

Joo-Youn Cho, K. Yu, I. Jang, 2012, BioDrugs.

Aspirin Decreases Systemic Exposure to Clopidogrel Through Modulation of P‐Glycoprotein But Does Not Alter Its Antithrombotic Activity

K. Chu, S. Yoon, S. Ji, 2014, Clinical pharmacology and therapeutics.

Effect of renal function on the pharmacokinetics of fimasartan: a single-dose, open-label, Phase I study

Jongtae Lee, Y. Kim, K. Yu, 2014, Drug design, development and therapy.

Multiple-dose pharmacokinetics and pharmacodynamics of evogliptin (DA-1229), a novel dipeptidyl peptidase IV inhibitor, in healthy volunteers

Sang-Heon Cho, Joo-Youn Cho, K. Yu, 2014, Drug design, development and therapy.

The novel carboxylesterase 1 variant c.662A>G may decrease the bioactivation of oseltamivir in humans

Joo-Youn Cho, K. Yu, I. Jang, 2017, PloS one.

Pharmacokinetics, Safety and Tolerability of DA-6034, an Anti-Inflammatory Agent, After Single and Multiple Oral Administrations in Healthy Volunteers

Jung-Ryul Kim, I. Jang, K. Lim, 2013, Clinical Drug Investigation.

Pharmacokinetics and pharmacodynamics of intravenous dexmedetomidine in healthy Korean subjects

I. Jang, W. Wisemandle, K. Lim, 2012, Journal of clinical pharmacy and therapeutics.

Evaluation of pharmacokinetic characteristics of a novel anti‐IBD drug, DA‐6034, in healthy volunteers

K. Lim, K. Yu, M. Son, 2005 .

A first-in-human study to investigate the safety, tolerability, pharmacokinetics, and pharmacodynamics of KM-819 (FAS-associated factor 1 inhibitor), a drug for Parkinson’s disease, in healthy volunteers

K. Lim, Joseph W. Kim, Min-Kyoung Kim, 2019, Drug design, development and therapy.

Pharmacokinetics and tolerability of the new second-generation nonnucleoside reverse- transcriptase inhibitor KM-023 in healthy subjects

Joo-Youn Cho, K. Yu, S. Schneider, 2014, Drug design, development and therapy.

Effect of UGT2B7 Genotype on Pharmacokinetics of Valproate in Human Healthy Subjects

Joo-Youn Cho, K. Yu, Jung-Ryul Kim, 2004 .

Pharmacokinetic study of single and multiple oral administrations of 2 mg dienogest in healthy Korean women.

Joong-Shin Park, K. Yu, I. Jang, 2013, Contraception.

Predictive performance of gentamicin dosing nomograms

K. Yu, K. Lim, Howard Lee, 2014, Drug Design, Development and Therapy.

Potential interactions between cilostazol and probucol: a two-part, single-dose, open-label study in healthy Korean male volunteers.

K. Yu, I. Jang, K. Lim, 2009, Clinical therapeutics.

Pharmacokinetic properties and effects of PT302 after repeated oral glucose loading tests in a dose-escalating study.

Sang-Heon Cho, K. Yu, I. Jang, 2014, Clinical therapeutics.

A positron emission tomography microdosing study with sertraline in healthy volunteers.

Jae Sung Lee, Yun-Sang Lee, Kwang-Hee Shin, 2012, International journal of clinical pharmacology and therapeutics.

Effects of dexamethasone coadministered with oseltamivir on the pharmacokinetics of oseltamivir in healthy volunteers

Joo-Youn Cho, K. Yu, Sang-Hyuk Lee, 2017, Drug design, development and therapy.

Pharmacokinetic characteristics of bepotastine besilate in healthy subjects

K. Yu, Hyeong-Seok Lim, I. Jang, 2007 .

Investigation of bioequivalence of a new fixed‐dose combination of acarbose and metformin with the corresponding loose combination as well as the drug–drug interaction potential between both drugs in healthy adult male subjects

E. Brendel, Y. Liu, I. Jang, 2014, Journal of clinical pharmacy and therapeutics.

An open-label, single-dose, parallel-group, dose-increasing study comparing the pharmacokinetics and tolerability of pilsicainide hydrochloride in healthy Korean and Japanese male subjects.

K. Yu, Jung-Ryul Kim, I. Jang, 2009, Clinical therapeutics.

Apple juice greatly reduces systemic exposure to atenolol.

K. Ohashi, Joo-Youn Cho, K. Yu, 2013, British journal of clinical pharmacology.

A pharmacokinetic comparison of two voriconazole formulations and the effect of CYP2C19 polymorphism on their pharmacokinetic profiles

Joo-Youn Cho, K. Yu, I. Jang, 2015, Drug design, development and therapy.

Effects of Proton Pump Inhibitors on Metformin Pharmacokinetics and Pharmacodynamics

Joo-Youn Cho, K. Yu, I. Jang, 2014, Drug Metabolism and Disposition.

Multiple-dose pharmacokinetics of fesoterodine sustained-release in healthy Korean volunteers.

Joo-Youn Cho, K. Yu, I. Jang, 2012, International journal of clinical pharmacology and therapeutics.

Pharmacokinetic comparison of a new glimepiride 1-mg + metformin 500-mg combination tablet formulation and a glimepiride 2-mg + metformin 500-mg combination tablet formulation: a single-dose, randomized, open-label, two-period, two-way crossover study in healthy, fasting Korean male volunteers.

Joo-Youn Cho, K. Yu, Jung-Ryul Kim, 2009, Clinical therapeutics.

The Effects of Moxifloxacin on QTc Interval in Healthy Korean Male Subjects

Jongtae Lee, D. Yim, Joo-Youn Cho, 2014, Drugs in R&D.

Tolerability and Pharmacokinetics of Lobeglitazone, a Novel Peroxisome Proliferator-Activated Receptor-γ Agonist, After a Single Oral Administration in Healthy Female Subjects

Joo-Youn Cho, K. Yu, I. Jang, 2014, Clinical Drug Investigation.

Pharmacokinetics and effect on the corrected QT interval of single-dose escitalopram in healthy elderly compared with younger adults

Sang-In Park, Joo-Youn Cho, K. Yu, 2017, International clinical psychopharmacology.

K. Lim, S. Jhee, Hyun Sok Kim, 2019 .

Joo-Youn Cho, K. Yu, I. Jang, 2010, Clinical therapeutics.

Modeling of Brain D2 Receptor Occupancy‐Plasma Concentration Relationships with a Novel Antipsychotic, YKP1358, Using Serial PET Scans in Healthy Volunteers

Jae Kyeong Jeong, H W Kim, H. Kim, 2007, Clinical pharmacology and therapeutics.

comparison of the pharmacokinetics and tolerability of HCP1004 (a fixed-dose combination of naproxen and esomeprazole strontium) and ViMOVO ® (a marketed fixed-dose combination of naproxen and esomeprazole magnesium) in healthy volunteers

K. Yu, K. Lim, Yoonjung Choi, 2015 .

novel nanocrystal formulation of megestrol acetate has improved bioavailability compared with the conventional micronized formulation in the fasting state

K. Yu, I. Jang, K. Lim, 2014 .

novel nanocrystal formulation of megestrol acetate has improved bioavailability compared with the conventional micronized formulation in the fasting state

K. Yu, I. Jang, K. Lim, 2014 .

Comparison of pharmacokinetics between new quinolone antibiotics: the zabofloxacin hydrochloride capsule and the zabofloxacin aspartate tablet

Joo-Youn Cho, K. Yu, K. Lim, 2013, Current medical research and opinion.

Population Pharmacokinetics of Theophylline in Premature Korean Infants

Joo-Youn Cho, K. Yu, I. Jang, 2013, Therapeutic drug monitoring.