H. van der Boom

发表

Diet-induced hyperlipoproteinemia and atherosclerosis in apolipoprotein E3-Leiden transgenic mice.

R. Frants, L. Havekes, A. M. van den Maagdenberg, 1994, The Journal of clinical investigation.

Triglyceride-rich lipoproteins of subjects heterozygous for apolipoprotein E2(Lys146-->Gln) are inefficiently converted to cholesterol-rich lipoproteins.

P. de Knijff, L. Havekes, A. M. van den Maagdenberg, 1994, Atherosclerosis.

Apolipoprotein E Is Resistant to Intracellular Degradation in Vitro and in Vivo

T. V. van Berkel, L. Havekes, H. van der Boom, 2000, The Journal of Biological Chemistry.

Transgenic mice carrying the apolipoprotein E3-Leiden gene exhibit hyperlipoproteinemia.

R. Frants, L. Havekes, A. M. van den Maagdenberg, 1993, The Journal of biological chemistry.

In the Absence of Endogenous Mouse Apolipoprotein E, Apolipoprotein E*2(Arg-158 → Cys) Transgenic Mice Develop More Severe Hyperlipoproteinemia than Apolipoprotein E*3-Leiden Transgenic Mice*

K. V. van Dijk, L. Havekes, M. Hofker, 1996, The Journal of Biological Chemistry.

Stimulation of the in Vivo Production of Very Low Density Lipoproteins by Apolipoprotein E Is Independent of the Presence of the Low Density Lipoprotein Receptor*

B. Teusink, K. V. van Dijk, L. Havekes, 2001, The Journal of Biological Chemistry.

Apolipoprotein C-III deficiency accelerates triglyceride hydrolysis by lipoprotein lipase in wild-type and apoE knockout mice.

T. V. van Berkel, L. Havekes, V. Dahlmans, 2001, Journal of lipid research.

Reversal of hypercholesterolemia in apolipoprotein E2 and apolipoprotein E3-Leiden transgenic mice by adenovirus-mediated gene transfer of the VLDL receptor.

K. V. van Dijk, L. Havekes, M. Hofker, 1998, Arteriosclerosis, thrombosis, and vascular biology.

Reversal of hyperlipidaemia in apolipoprotein C1 transgenic mice by adenovirus-mediated gene delivery of the low-density-lipoprotein receptor, but not by the very-low-density-lipoprotein receptor.

G. Siest, K. V. van Dijk, L. Havekes, 1999, The Biochemical journal.

Increased response to cholesterol feeding in apolipoprotein C1-deficient mice.

B. Wieringa, J. V. van Deursen, R. Frants, 1995, The Biochemical journal.

Dietary plant stanol esters reduce VLDL cholesterol secretion and bile saturation in apolipoprotein E*3-Leiden transgenic mice.

R. Mensink, L. Havekes, W. Duyvenvoorde, 2001, Arteriosclerosis, thrombosis, and vascular biology.

Hyperlipidemia of ApoE2(Arg(158)-Cys) and ApoE3-Leiden transgenic mice is modulated predominantly by LDL receptor expression.

K. V. van Dijk, L. Havekes, M. Hofker, 1999, Arteriosclerosis, thrombosis, and vascular biology.

Rosuvastatin Reduces Plasma Lipids by Inhibiting VLDL Production and Enhancing Hepatobiliary Lipid Excretion in ApoE*3-Leiden Mice

L. Havekes, F. Kuipers, V. Bloks, 2005, Journal of cardiovascular pharmacology.

Molecular aspects of age-related changes in albumin synthesis in female WAG/Rij rats.

S. Yap, H. van der Boom, G. Horbach, 1988, Life sciences.

Lipoprotein lipase stimulates the binding and uptake of moderately oxidized low-density lipoprotein by J774 macrophages.

L. Havekes, H. van der Boom, W. Hendriks, 1996, The Biochemical journal.

Inefficient degradation of triglyceride-rich lipoprotein by HepG2 cells is due to a retarded transport to the lysosomal compartment.

R. Frants, L. Havekes, H. van der Boom, 1993, The Journal of biological chemistry.

Its Cholesterol-Lowering Effect in ApoE * 3-Leiden Mice Acyl-CoA : Cholesterol Acyltransferase Inhibitor Avasimibe Reduces Atherosclerosis in Addition to

J. Jukema, A. Van der Laarse, L. Havekes, 2001 .

Modulation of very low density lipoprotein production and clearance contributes to age- and gender- dependent hyperlipoproteinemia in apolipoprotein E3-Leiden transgenic mice.

R. Frants, L. Havekes, M. Hofker, 1996, The Journal of clinical investigation.