H. Leaver

发表

Intracellular oxidation by human glioma cell populations: effect of arachidonic acid.

I. Whittle, J. Williams, H. Leaver, 2004, Prostaglandins, leukotrienes, and essential fatty acids.

Microsomal prostaglandin E synthase-1 regulates human glioma cell growth via prostaglandin E2–dependent activation of type II protein kinase A

I. Whittle, M. Rizzo, O. Trifan, 2006, Molecular Cancer Therapeutics.

Acute phase responses following minimal access and conventional thoracic surgery.

P. Yap, W. Walker, H. Leaver, 2001, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Arachidonic acid activation of monocyte and neutrophil reactive oxygen in lung cancer patients undergoing pulmonary resection.

J. Williams, P. Yap, W. Walker, 1996, Biologicals : journal of the International Association of Biological Standardization.

Blood immunoglobulins, complement and TNF receptor following minimally invasive surgery in patients undergoing pulmonary lobectomy

W. Walker, H. Leaver, D. Rotondo, 2015 .

Cellular and Humoral Responses following Minimally Invasive Surgery: Role of Reactive Oxygen Species

W. Walker, H. Leaver, D. Rotondo, 2015 .

Peroxides in human leucocytes in acute septic shock: a preliminary study of acute phase changes and mortality

G. Smith, P. Yap, P. Williams, 1995, European journal of clinical investigation.

Apoptosis in human primary brain tumours: actions of arachidonic acid.

A. Gregor, I. Whittle, J. Williams, 1998, Prostaglandins, leukotrienes, and essential fatty acids.

Macrophage prostaglandin E2 and oxidative responses to endotoxin during immunosuppression associated with anaesthesia and transfusion.

G. Raab, D. Carter, P. Yap, 1993, Prostaglandins, leukotrienes, and essential fatty acids.

Therapeutic implications of disorders of cell death signalling: membranes, micro‐environment, and eicosanoid and docosanoid metabolism

H. Leaver, D. Rotondo, J. Davidson, 2012, British journal of pharmacology.

Distribution of arachidonic acid and other fatty acids in the lipids of guinea-pig uterus and plasma in relation to uterine prostaglandin synthesis.

H. Leaver, N. Poyser, 1981, Journal of reproduction and fertility.

Highly unsaturated fatty acid induced tumour regression in glioma pharmacodynamics and bioavailability of gamma linolenic acid in an implantation glioma model: effects on tumour biomass, apoptosis and neuronal tissue histology.

I. Whittle, S. Wharton, H. Leaver, 2002, Prostaglandins, leukotrienes, and essential fatty acids.

Arachidonic acid induces brain endothelial cell apoptosis via p38-MAPK and intracellular calcium signaling.

Shukun Wang, M. Rizzo, A. Cohen-Gadol, 2015, Microvascular research.

The effect of oxytocin, estrogen, calcium ionophore A23187 and hydrocortisone on prostaglandin F2α and 6-oxo-prostaglandin F1α production by cultured human endometrial and myometrial explants

H. Leaver, D. Richmond, 1984 .

Evidence for two particulate cholesterol ester hydrolase enzymes in rat corpus luteum.

G. S. Boyd, H. Leaver, 1981, Journal of steroid biochemistry.

Control of steroidogenesis in rat corpus luteum: the rate of access of cholesterol to the active site of the cholesterol side-chain cleavage enzyme.

G. S. Boyd, H. Leaver, 1981, The Journal of endocrinology.

Prions: Properties, Occurrence, Modes of Transmission and Relevance for Blood Transfusion and Blood Derivatives

P. Yap, P. Yap, H. Leaver, 1998, Vox sanguinis.

Endotoxin releases platelet-activating factor from human monocytes in vitro.

G. Smith, P. Yap, W. Ross, 1990, Immunopharmacology.

The effect of endotoxin lipopolysaccharide from different bacterial species on the generation of intracellular inositol trisphosphate and superoxide in a human phagocytic cell line.

P. Yap, H. Leaver, M. Aldhous, 1990, FEMS microbiology immunology.

Prostaglandin E2 in induction of labour: a pharmacokinetic study of dose and treatment protocols.

H. Leaver, D. Hutchon, D. Richmond, 1988, Prostaglandins, leukotrienes, and essential fatty acids.

Control of endometrial prostaglandin output in vitro during the estrous cycle of the guinea-pig: influence of estradiol 17-beta, progesterone, oxytocin and calcium ionophore A23187.

H. Leaver, A. Seawright, 1982, Prostaglandins, leukotrienes, and medicine.

Glioma Cell Death: Cell–Cell Interactions and Signalling Networks

I. Whittle, H. Leaver, M. T. Rizzo, 2010, Molecular Neurobiology.

Prostaglandin E2 activates cAMP response element-binding protein in glioma cells via a signaling pathway involving PKA-dependent inhibition of ERK.

M. Rizzo, H. Leaver, P. Bidwell, 2010, Prostaglandins & other lipid mediators.

Antitumour and pro-apoptotic actions of highly unsaturated fatty acids in glioma.

A. Gregor, I. Whittle, S. Wharton, 2002, Prostaglandins, leukotrienes, and essential fatty acids.

The Incidence of Post-operative Hypoxaemia Following Lobectomy and Pneumonectomy: A pilot study

H. Leaver, S. Holgate, J. Conway, 1994 .

Pathways controlling the superoxide response during phagocyte differentiation: involvement of arachidonic acid and Ca2+ in the response to bacterial endotoxin.

P. Yap, A. Dhillon, W. Ross, 1992, FEMS microbiology immunology.

Antitumour actions of highly unsaturated fatty acids: cell signalling and apoptosis.

I. Whittle, H. Leaver, M. T. Rizzo, 2002, Prostaglandins, leukotrienes, and essential fatty acids.

Network Analysis of Arachidonic Acid Pathophysiology in Human Phagocytes and Primary Brain Tumors a

A. Gregor, I. Whittle, J. Ironside, 1997, Annals of the New York Academy of Sciences.

Changes in Progesterone, Oestradiol 17β, and Intrauterine Prostaglandin E2 during Late Gestation in Sheep Experimentally Infected with an Ovine Abortion Strain of Chlamydia psittaci

D. Buxton, H. Leaver, I. Anderson, 1989 .

Action of gonadotrophic hormones on cholesterol side-chain cleavage and cholesterol ester hydrolase in the ovary of the immature rat.

G. S. Boyd, H. Leaver, 1981, Journal of reproduction and fertility.

Brain Endothelial Cell Death: Modes, Signaling Pathways, and Relevance to Neural Development, Homeostasis, and Disease

M. Rizzo, H. Leaver, Maria Teresa Rizzo, 2010, Molecular Neurobiology.

c-jun amino-terminal kinase and mitogen activated protein kinase 1/2 mediate hepatocyte growth factor-induced migration of brain endothelial cells.

M. Rizzo, H. Leaver, G. Khan, 2007, Experimental cell research.

The effect of dietary ω3 and ω6 polyunsaturated fatty acids on gestation, parturition and prostaglandin E2 in intrauterine tissues and the kidney

D. Mellor, H. Leaver, H. Dyson, 1986 .

Arachidonic acid uptake into and release from guinea-pig endometrium in vitro on days 7 and 15 of the oestrous cycle.

H. Leaver, N. Poyser, A. C. Ning, 1983, Prostaglandins, leukotrienes, and medicine.

The influence of dietary essential fatty acids on uterine C20 and C22 fatty acid composition.

P. Yap, H. Leaver, A. Howie, 1992, Prostaglandins, leukotrienes, and essential fatty acids.

Calcium-sensitive mitochondrial membrane potential in human platelets and intrinsic signals of cell death

C. Prowse, H. Leaver, M. T. Rizzo, 2006, Platelets.

Effects of N-6 essential fatty acids on glioma invasion and growth: experimental studies with glioma spheroids in collagen gels.

I. Whittle, S. Wharton, H. Leaver, 1999, Journal of neurosurgery.

Immunologic and stress responses following video-assisted thoracic surgery and open pulmonary lobectomy in early stage lung cancer.

W. Walker, H. Leaver, H. Leaver, 2007, Thoracic surgery clinics.

The effect of chlamydial infection on the initiation of premature labour: serial measurements of intrauterine prostaglandin E2 in amniotic fluid, allantoic fluid and utero-ovarian vein, using catheterised sheep experimentally infected with an ovine abortion strain of Chlamydia psittaci.

H. Leaver, I. Anderson, A. Howie, 1989, Prostaglandins, leukotrienes, and essential fatty acids.

Effect of blood transfusion on survival after esophagogastrectomy for carcinoma.

R. Elton, P. Yap, E. Cameron, 1998, The Annals of thoracic surgery.

The development of necrosis and apoptosis in glioma: experimental findings using spheroid culture systems*

I. Whittle, S. Wharton, H. Leaver, 2001, Neuropathology and applied neurobiology.

Apoptosis in human primary brain tumours.

I. Whittle, S. Wharton, J. Ironside, 1998, British journal of neurosurgery.

Interaction of human monocytes and endothelial cells potentiates the oxidative response to phorbol myristoyl acetate (PMA) and endotoxin in vitro.

G. Smith, P. Yap, K. Sanderson, 1989, FEMS microbiology immunology.

Phorbol myristoyl acetate- and endotoxin-stimulated generation of intracellular superoxide in human monocytes during endotoxaemia

P. Yap, H. Leaver, K. Knox, 1987 .

Oxidative Stress and Brain Endothelial Cells

M. Rizzo, H. Leaver, M. Saquib, 2014 .

Therapeutic applications of phagocytes.

P. Yap, H. Leaver, 1989, FEMS microbiology immunology.

Developmental changes in the fatty acids of rat uterus and the influence of dietary essential fatty acids.

P. Yap, H. Leaver, A. Howie, 1992, Prostaglandins, Leukotrienes and Essential Fatty Acids.

The biosynthesis of the 3-series prostaglandins in rat uterus after alpha-linolenic acid feeding: mass spectroscopy of prostaglandins E and F produced by rat uteri in tissue culture.

H. Leaver, A. Howie, N. H. Wilson, 1991, Prostaglandins, leukotrienes, and essential fatty acids.

Amniotic fluid prostaglandins F2 alpha and E2, measured at artificial rupture of the membranes, predict the subsequent progress of labour.

H. Leaver, D. Hutchon, H. MacPherson, 1987, Prostaglandins, leukotrienes, and medicine.

New pathways of phagocyte activation: an overview.

P. Yap, H. Leaver, J. Stewart, 1992, FEMS microbiology immunology.

Prostaglandin E2 production by rat peritoneal macrophages: role of cellular and humoral factors in vivo in transfusion-associated immunosuppression.

G. Raab, D. Carter, P. Yap, 1990, FEMS microbiology immunology.

Phagocyte responses to endotoxin: intracellular signals and oxidative activity.

G. Smith, P. Yap, H. Leaver, 1989, FEMS microbiology immunology.

The endotoxin receptor on mononuclear phagocytes.

J. Parratt, G. Ramsay, G. Smith, 1990, FEMS microbiology immunology.

Endotoxin binding, and changes in monocyte sub-populations subsequent to binding, detected by flow cytometry.

G. Smith, P. Yap, P. Williams, 1989, FEMS microbiology immunology.