R. Onose

发表

Reveromycins, new inhibitors of eukaryotic cell growth. II. Biological activities.

H. Koshino, H. Osada, K. Isono, 1992, The Journal of antibiotics.

Enantio- and diastereoselective total synthesis of (+)-panepophenanthrin, a ubiquitin-activating enzyme inhibitor, and biological properties of its new derivatives.

H. Kakeya, H. Osada, Junichiro Yamaguchi, 2006, Chemistry, an Asian journal.

Epoxytwinol A, a novel unique angiogenesis inhibitor with C2 symmetry, produced by a fungus.

H. Koshino, H. Kakeya, H. Osada, 2005, Chemical communications.

Epoxyquinol A, a highly functionalized pentaketide dimer with antiangiogenic activity isolated from fungal metabolites.

H. Koshino, H. Kakeya, H. Osada, 2002, Journal of the American Chemical Society.

Inhibition of cyclin D1 expression and phosphorylation of retinoblastoma protein by phosmidosine, a nucleotide antibiotic.

F. Matsumura, H. Kakeya, H. Osada, 1998, Cancer research.

Morphology reversion activity of phosmidosine and phosmidosine B, a newly isolated derivative, on src transformed NRK cells.

H. Osada, R. Onose, N. Matsuura, 1996, The Journal of antibiotics.

A new inhibitor of protein kinase C, RK-1409 (7-oxostaurosporine). I. Taxonomy and biological activity.

H. Koshino, H. Osada, T. Kudo, 1992, The Journal of antibiotics.

A new inhibitor of protein kinase C, RK-1409B (4'-demethylamino-4'-hydroxy-3'-epistaurosporine).

H. Koshino, H. Osada, K. Isono, 1992, The Journal of antibiotics.

A new indolocarbazole antibiotic, RK-286D.

M. Satake, H. Koshino, H. Osada, 1992, The Journal of antibiotics.

Cytotrienin A, a novel apoptosis inducer in human leukemia HL-60 cells.

H. Zhang, H. Kakeya, H. Osada, 1997, The Journal of antibiotics.

Activation of MST/Krs and c-Jun N-terminal Kinases by Different Signaling Pathways during Cytotrienin A-induced Apoptosis*

M. Watabe, H. Kakeya, R. Onose, 2000, The Journal of Biological Chemistry.

Activation of a 36‐kD MBP Kinase, an Active Proteolytic Fragment of MST/Krs Proteins, during Anticancer Drug‐Induced Apoptosis

H. Kakeya, H. Osada, R. Onose, 1999, Annals of the New York Academy of Sciences.

Epoxyquinol B, a fungal metabolite with a potent antiangiogenic activity.

H. Koshino, H. Kakeya, H. Osada, 2002, The Journal of antibiotics.

Azaspirene: a novel angiogenesis inhibitor containing a 1-oxa-7-azaspiro[4.4]non-2-ene-4,6-dione skeleton produced by the fungus Neosartorya sp.

Yukihiro Asami, H. Kakeya, H. Osada, 2002, Organic letters.

PC-766B' and PC-766b, 16-membered macrolide angiogenesis inhibitors produced by Nocardia sp. RK97-56

H. Kakeya, H. Osada, A. Takatsuki, 2002 .

Acetophthalidin, a novel inhibitor of mammalian cell cycle, produced by a fungus isolated from a sea sediment.

M. Ubukata, H. Kakeya, H. Osada, 1996, The Journal of antibiotics.

Biotransformation of the Mycotoxin, Zearalenone, to a Non-estrogenic Compound by a Fungal Strain of Clonostachys sp.

M. Kimura, I. Yamaguchi, H. Kakeya, 2002, Bioscience, biotechnology, and biochemistry.

Lucilactaene, a new cell cycle inhibitor in p53-transfected cancer cells, produced by a Fusarium sp.

C. Norbury, L. Nie, T. Beppu, 2001, The Journal of antibiotics.

Novel mammalian cell cycle inhibitors, tryprostatins A, B and other diketopiperazines produced by Aspergillus fumigatus. I. Taxonomy, fermentation, isolation and biological properties.

H. Kakeya, H. Osada, C. Cui, 1996, The Journal of antibiotics.

Tryprostatins A and B, novel mammalian cell cycle inhibitors produced by Aspergillus fumigatus.

M. Ubukata, H. Kakeya, H. Osada, 1995, The Journal of antibiotics.

A new cyclic lipopeptide antibiotic, enamidonin.

H. Koshino, H. Osada, K. Isono, 1995, The Journal of antibiotics.

Screening of cell cycle inhibitors from microbial metabolites by a bioassay using a mouse cdc2 mutant cell line, tsFT210.

F. Hanaoka, H. Osada, C. Cui, 1997, Bioorganic & medicinal chemistry.

Tryprostatins A and B, novel mammalian cell cycle inhibitors produced by Aspergillus fumigatus.

M. Ubukata, H. Kakeya, H. Osada, 1995, The Journal of antibiotics.

Novel MammalianCell Cycle Inhibitors , Tryprostatins A , B and Other Diketopiperazines Produced by Aspergillus fumigatus I . Taxonomy , Fermentation , Isolation and Biological Properties

Cui, Hideaki, Hiroyuki, 2006 .

Acetophthalidin, a Novel Inhibitor of Mammalian Cell Cycle, Produced by a Fungus Isolated from a Sea Sediment

M. Ubukata, H. Kakeya, H. Osada, 1996 .

Enantio- and diastereoselective total synthesis of EI-1941-1, -2, and -3, inhibitors of interleukin-1beta converting enzyme, and biological properties of their derivatives.

H. Kakeya, H. Osada, R. Onose, 2005, The Journal of organic chemistry.

Isolation, and biological properties of a new cell cycle inhibitor, curvularol, isolated from Curvularia sp. RK97-F166.

R. Usami, H. Osada, R. Onose, 2001, The Journal of antibiotics.

Caspase-mediated activation of a 36-kDa myelin basic protein kinase during anticancer drug-induced apoptosis.

H. Kakeya, H. Osada, R. Onose, 1998, Cancer research.

Selective inhibition of platelet-derived growth factor (PDGF) receptor autophosphorylation and PDGF-mediated cellular events by a quinoline derivative.

S. Oyama, K. Nakamura, R. Onose, 1997, Experimental cell research.

RK-805, an endothelial-cell-growth inhibitor produced by Neosartorya sp., and a docking model with methionine aminopeptidase-2

Yukihiro Asami, M. Toi, H. Kakeya, 2004 .

Isolation and Biological Properties of a New Cell Cycle Inhibitor, Curvularol, Isolated from Curvularia sp. RK97-F166.

K. Horikoshi, R. Usami, H. Osada, 2001 .

Reveromycins, new inhibitors of eukaryotic cell growth. II. Biological activities.

Hidetoshi Takahashi, M. Yoshihama, R. Onose, 1992, The Journal of antibiotics.