Y. Shin

发表

Fluorous mixture synthesis of (-)-dictyostatin and three stereoisomers.

B. Day, D. Curran, Y. Fukui, 2006, Organic letters.

Total synthesis and biological evaluation of C16 analogs of (-)-dictyostatin.

B. Day, D. Curran, Y. Shin, 2007, Journal of medicinal chemistry.

Structure-Activity Relationships and X-ray Structures Describing the Selectivity of Aminopyrazole Inhibitors for c-Jun N-terminal Kinase 3 (JNK3) over p38*

P. Lograsso, J. Habel, Y. Ling, 2009, Journal of Biological Chemistry.

Design and synthesis of 1-aryl-5-anilinoindazoles as c-Jun N-terminal kinase inhibitors.

M. Cameron, T. Kamenecka, Y. Shin, 2013, Bioorganic & medicinal chemistry letters.

Synthesis and SAR of novel quinazolines as potent and brain-penetrant c-jun N-terminal kinase (JNK) inhibitors.

P. Lograsso, M. Cameron, Y. Ling, 2011, Bioorganic & medicinal chemistry letters.

Synthesis and SAR of 4-(pyrazol-3-yl)-pyridines as novel c-jun N-terminal kinase inhibitors.

P. Lograsso, M. Cameron, Y. Ling, 2011, Bioorganic & medicinal chemistry letters.

A novel class of highly potent, selective, and non-peptidic inhibitor of Ras farnesyltransferase (FTase).

Y. Shin, J. Kim, H. Lee, 2001, Bioorganic & medicinal chemistry letters.

3-Aryl-4-aryloyl-1-(1H-imidazol-5-yl)methylpyrrole, a novel class of farnesyltransferase inhibitors.

Y. Shin, J. Kim, H. Lee, 2001, Bioorganic & medicinal chemistry letters.

Synthesis and SAR of piperazine amides as novel c-jun N-terminal kinase (JNK) inhibitors.

P. Lograsso, J. Habel, Y. Ling, 2009, Bioorganic & medicinal chemistry letters.

Structural and Dynamic Elucidation of a Non-acid PPAR γ Partial Agonist : SR 1988

P. Griffin, J. Bruning, R. Frkic, 2018 .

Structural and Dynamic Elucidation of a Non-acid PPARγ Partial Agonist: SR1988

P. Griffin, J. Bruning, R. Frkic, 2018, Nuclear receptor research.

Synthesis and biological evaluation of ( − )-dictyostatin and stereoisomers

B. Day, D. Curran, E. Hamel, 2022 .

Synthesis and SAR of 2,4-diaminopyrimidines as potent c-jun N-terminal kinase inhibitors

M. Cameron, Y. Ling, T. Kamenecka, 2012 .

Design, Synthesis, and Biological Evaluation of Indole Biphenylcarboxylic Acids as PPARγ Antagonists.

Scott A. Busby, Ruben D. Garcia-Ordonez, P. Griffin, 2015, ACS medicinal chemistry letters.

Anti-Diabetic Actions of a Non-Agonist PPARγ Ligand Blocking Cdk5-Mediated Phosphorylation

Scott A. Busby, M. J. Chalmers, Alexander S. Banks, 2011, Nature.

Synthesis and SAR of tetrahydroisoquinolines as Rev-erbα agonists.

D. Kojetin, Subhashish Banerjee, M. Cameron, 2012, Bioorganic & Medicinal Chemistry Letters.

Synthesis and biological evaluation of (-)-16-normethyldictyostatin: a potent analogue of (-)-dictyostatin.

B. Day, D. Curran, E. Hamel, 2005, Organic letters.

Discodermolide/Dictyostatin hybrids: synthesis and biological evaluation.

B. Day, D. Curran, Y. Shin, 2002, Organic letters.

Total synthesis of (-)-dictyostatin: confirmation of relative and absolute configurations.

D. Curran, Y. Fukui, Arndt M. Brückner, 2004, Angewandte Chemie.

Pharmacological Targeting of the Mammalian Clock Regulates Sleep Architecture and Emotional Behavior

A. Roberts, Subhashish Banerjee, L. Solt, 2014, Nature Communications.

Enantioselective total synthesis of (+)-gliocladin C.

L. Overman, Y. Shin, 2007, Organic letters.

Confirmation of a linkage between H‐Ras and MMP‐13 expression as well as MMP‐9 by chemical genomic approach

Cheol‐Hee Kim, D. Han, K. Son, 2006, International journal of cancer.

Regulation of Circadian Behavior and Metabolism by Synthetic REV-ERB Agonists

J. Takahashi, T. Hughes, D. Kojetin, 2012, Nature.

Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy

J. Eeckhoute, S. Lancel, R. Neviere, 2013, Nature Medicine.

An alternate binding site for PPARγ ligands

Travis S. Hughes, Ian Mitchelle S. de Vera, Douglas J. Kojetin, 2014, Nature Communications.

Synthesis and activity of substituted heteroaromatics as positive allosteric modulators for α4β2α5 nicotinic acetylcholine receptors.

P. Kenny, J. Lindstrom, Jingyi Wang, 2014, Bioorganic & medicinal chemistry letters.

Tubulin assembly, taxoid site binding, and cellular effects of the microtubule-stabilizing agent dictyostatin.

K. Giuliano, B. Day, D. Curran, 2005, Biochemistry.

SR2067 Reveals a Unique Kinetic and Structural Signature for PPARγ Partial Agonism.

Patrick R Griffin, Mi Ra Chang, P. Griffin, 2016, ACS chemical biology.

Defining a conformational ensemble that directs activation of PPARγ

Ian Mitchelle S. de Vera, T. Cheatham, T. Hughes, 2018, Nature Communications.

Defining a conformational ensemble that directs activation of PPARγ

Ian Mitchelle S. de Vera, T. Cheatham, T. Hughes, 2018, Nature Communications.

Systems cell biology knowledge created from high content screening.

Dennis P Curran, Billy W Day, John S Lazo, 2005, Assay and drug development technologies.

Cell-Based and Biochemical Structure-Activity Analyses of Analogs of the Microtubule Stabilizer Dictyostatin

B. Day, D. Curran, Y. Fukui, 2008, Molecular Pharmacology.

Simplified discodermolide analogues: synthesis and biological evaluation of 4-epi-7-dehydroxy-14,16-didemethyl-(+)-discodermolides as microtubule-stabilizing agents.

B. Day, D. Curran, Y. Shin, 2003, Journal of medicinal chemistry.

Rev-erb-alpha modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy

J. Eeckhoute, S. Lancel, R. Neviere, 2019 .