Guilian M. Xu

发表

Environmental Enrichment Mitigates Cognitive Deficits in a Mouse Model of Alzheimer's Disease

D. Borchelt, A. Savonenko, S. Younkin, 2005, The Journal of Neuroscience.

Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase

Joanna L. Jankowsky, Nancy A. Jenkins, D. Borchelt, 2004 .

Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase.

D. Borchelt, S. Younkin, L. Younkin, 2004, Human molecular genetics.

Differential induction of mutant SOD1 misfolding and aggregation by tau and α-synuclein pathology

D. Borchelt, B. Giasson, Jada Lewis, 2018, Molecular neurodegeneration.

Abeta deposition does not cause the aggregation of endogenous tau in transgenic mice.

D. Borchelt, V. Gonzales, Guilian M. Xu, 2002, Alzheimer disease and associated disorders.

Bcl6 modulates innate immunity by controlling macrophage activity and plays critical role in experimental autoimmune encephalomyelitis

Mingyao Liu, Dali Li, Lei Zhou, 2020, European journal of immunology.

Combinatorial model of amyloid β and tau reveals synergy between amyloid deposits and tangle formation

Kristen R. Ibanez, Paramita Chakrabarty, B. Giasson, 2021, Neuropathology and applied neurobiology.

Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy

D. Borchelt, M. Swanson, Jada Lewis, 2018, Scientific Reports.

Changes in proteome solubility indicate widespread proteostatic disruption in mouse models of neurodegenerative disease

D. Borchelt, B. Giasson, Jada Lewis, 2018, Acta Neuropathologica.

A Deposition Does Not Cause the Aggregation of Endogenous Tau in Transgenic Mice

D. Borchelt, V. Gonzales, Guilian M. Xu, 2002 .

Pathogenic tau recruits wild-type tau into brain inclusions and induces gut degeneration in transgenic SPAM mice

D. Borchelt, T. Golde, M. Tansey, 2022, Communications Biology.

Reduction of low-density lipoprotein receptor-related protein (LRP1) in hippocampal neurons does not proportionately reduce, or otherwise alter, amyloid deposition in APPswe/PS1dE9 transgenic mice

D. Borchelt, Guilian M. Xu, S. Fromholt, 2012, Alzheimer's Research & Therapy.

Direct and indirect mechanisms for wild-type SOD1 to enhance the toxicity of mutant SOD1 in bigenic transgenic mice.

D. Borchelt, Guilian M. Xu, S. Fromholt, 2015, Human molecular genetics.

Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA

D. Borchelt, N. Jenkins, V. Gonzales, 2005, Neurobiology of Disease.

Complement and the Alternative Pathway Play an Important Role in LPS/D-GalN-Induced Fulminant Hepatic Failure

Yuzhang Wu, Yusen Zhou, Guangyu Zhao, 2011, PloS one.

Substantially elevating the levels of αB‐crystallin in spinal motor neurons of mutant SOD1 mice does not significantly delay paralysis or attenuate mutant protein aggregation

D. Borchelt, Zoe B Siemienski, Keith W Crosby, 2015, Journal of neurochemistry.

Lactic Acid Induces Aberrant Amyloid Precursor Protein Processing by Promoting Its Interaction with Endoplasmic Reticulum Chaperone Proteins

Guilian M. Xu, Kirsten A Weigel-Van Aken, Y. Xiang, 2010, Alzheimer's & Dementia.

Impact of APOE genotype on prion-type propagation of tauopathy

D. Borchelt, Paramita Chakrabarty, B. Giasson, 2022, Acta neuropathologica communications.

Deficiency of LIGHT signaling pathway exacerbates Chlamydia psittaci respiratory tract infection in mice.

Guilian M. Xu, Lili Chen, Chunxue Lu, 2016, Microbial pathogenesis.

Variation in the vulnerability of mice expressing human superoxide dismutase 1 to prion-like seeding: a study of the influence of primary amino acid sequence

Jacob I. Ayers, D. Borchelt, Guilian M. Xu, 2021, Acta Neuropathologica Communications.

Lipid Receptor G2A-Mediated Signal Pathway Plays a Critical Role in Inflammatory Response by Promoting Classical Macrophage Activation

Mingyao Liu, Dali Li, B. Zheng, 2021, The Journal of Immunology.

Experimental transmissibility of mutant SOD1 motor neuron disease

Jacob I. Ayers, D. Borchelt, Guilian M. Xu, 2014, Acta Neuropathologica.

Conformational specificity of the C4F6 SOD1 antibody; low frequency of reactivity in sporadic ALS cases

Jacob I. Ayers, D. Borchelt, J. Troncoso, 2014, Acta Neuropathologica Communications.

Modeling the Competition between Misfolded Aβ Conformers That Produce Distinct Types of Amyloid Pathology in Alzheimer’s Disease

D. Borchelt, Guilian M. Xu, S. Fromholt, 2022, Biomolecules.

Lymphotoxin αβ2 (Membrane Lymphotoxin) Is Critically Important for Resistance to Leishmania major Infection in Mice1

yang-xin fu, Guilian M. Xu, Yijun Fan, 2007, The Journal of Immunology.

Experimental mutagenesis of huntingtin to map cleavage sites: different outcomes in cell and mouse models.

D. Borchelt, Andrew T. N. Tebbenkamp, L. Tessarollo, 2014, Journal of Huntington's disease.

LIGHT Is Critical for IL-12 Production by Dendritic Cells, Optimal CD4+ Th1 Cell Response, and Resistance to Leishmania major1

yang-xin fu, S. Kung, Guilian M. Xu, 2007, The Journal of Immunology.

Murine Aβ over-production produces diffuse and compact Alzheimer-type amyloid deposits

D. Borchelt, T. Golde, Guilian M. Xu, 2015, Acta neuropathologica communications.

TAPPing into the potential of inducible tau/APP transgenic mice

D. Borchelt, Jada Lewis, Guilian M. Xu, 2022, Neuropathology and applied neurobiology.

Deficiency of CD40 Reveals an Important Role for LIGHT in Anti-Leishmania Immunity

yang-xin fu, Haidong Tang, Guilian M. Xu, 2015, The Journal of Immunology.

Leishmania Role for LIGHT in Anti-Deficiency of CD40 Reveals an Important

yang-xin fu, Haidong Tang, Guilian M. Xu, 2015 .

Immunity Leishmania Role for LIGHT in Anti-Deficiency of CD 40 Reveals an Important

yang-xin fu, Haidong Tang, Guilian M. Xu, 2015 .

BACE1, a Major Determinant of Selective Vulnerability of the Brain to Amyloid-β Amyloidogenesis, is Essential for Cognitive, Emotional, and Synaptic Functions

H. Cai, H. Wen, D. Borchelt, 2005, The Journal of Neuroscience.