E. Nizi

发表

Dihydroxypyrimidine-4-carboxamides as novel potent and selective HIV integrase inhibitors.

D. Hazuda, S. Harper, M. Rowley, 2007, Journal of medicinal chemistry.

Discovery of raltegravir, a potent, selective orally bioavailable HIV-integrase inhibitor for the treatment of HIV-AIDS infection.

D. Hazuda, M. Rowley, V. Summa, 2008, Journal of medicinal chemistry.

Discovery by organism based high-throughput screening of new multi-stage compounds affecting Schistosoma mansoni viability, egg formation and production

S. Harper, N. Gennari, M. Andreini, 2017, PLoS neglected tropical diseases.

The monoethyl ester of meconic acid is an active site inhibitor of HCV NS5B RNA-dependent RNA polymerase.

R. De Francesco, S. Altamura, V. Summa, 2004, Bioorganic & medicinal chemistry letters.

Development of peptidomimetics with a vinyl sulfone warhead as irreversible falcipain-2 inhibitors.

T. Schirmeister, M. D. Di Francesco, E. Nizi, 2008, Journal of medicinal chemistry.

Discovery of MK-5172, a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor.

M. Rudd, P. Coleman, S. Harper, 2012, ACS medicinal chemistry letters.

Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACs.

S. Harper, S. Altamura, N. Gennari, 2016, ACS medicinal chemistry letters.

Discovery of 4-((1-(1H-imidazol-2-yl)alkoxy)methyl)pyridines as a new class of Trypanosoma cruzi growth inhibitors.

S. Harper, V. Summa, P. Pace, 2020, Bioorganic & medicinal chemistry letters.

Novel macrocyclic inhibitors of hepatitis C NS3/4A protease featuring a 2-amino-1,3-thiazole as a P4 carbamate replacement.

U. Koch, M. Rowley, V. Summa, 2009, Journal of medicinal chemistry.

Discovery and synthesis of HIV integrase inhibitors: development of potent and orally bioavailable N-methyl pyrimidones.

Michael Rowley, Cristina Gardelli, Marco Ferrara, 2007, Journal of medicinal chemistry.

Nonpeptidic Vinyl and Allyl Phosphonates as Falcipain‐2 Inhibitors

T. Schirmeister, E. Nizi, M. Zappalà, 2008, ChemMedChem.

Solid phase synthesis of 2,6-disubstituted-4(3H)-pyrimidinones targeting HIV-1 reverse transcriptase

G. Maga, M. Botta, F. Messina, 1998 .

Improved Selective Class I HDAC and Novel Selective HDAC3 Inhibitors: Beyond Hydroxamic Acids and Benzamides.

S. Harper, V. Summa, P. Pace, 2018, ACS medicinal chemistry letters.

Identification of novel multi-stage histone deacetylase (HDAC) inhibitors that impair Schistosoma mansoni viability and egg production

N. Gennari, G. Paonessa, E. Nizi, 2018, Parasites & Vectors.

Novel peptidomimetics containing a vinyl ester moiety as highly potent and selective falcipain-2 inhibitors.

M. Leippe, T. Schirmeister, M. D. Di Francesco, 2009, Journal of medicinal chemistry.

Peptidomimetic nitrile inhibitors of malarial protease falcipain-2 with high selectivity against human cathepsins.

S. Harper, N. Gennari, G. Paonessa, 2018, Bioorganic & medicinal chemistry letters.

Capped dipeptide phenethylamide inhibitors of the HCV NS3 protease.

U. Koch, F. Narjes, V. Matassa, 2004, Bioorganic & medicinal chemistry letters.

Capped dipeptide α-Ketoacid inhibitors of the HCV NS3 protease

Uwe Koch, Cristina Gardelli, Victor Giulio Matassa, 2002 .

Identification of novel multi-stage histone deacetylase (HDAC) inhibitors that impair Schistosoma mansoni viability and egg production

N. Gennari, G. Paonessa, A. Guidi, 2018, Parasites & Vectors.

Dihydroxy-pyrimidine and N-methylpyrimidone HIV-integrase inhibitors: improving cell based activity by the quaternarization of a chiral center.

V. Summa, E. Muraglia, M. Orsale, 2009, Bioorganic & Medicinal Chemistry Letters.

Design and synthesis of bicyclic pyrimidinones as potent and orally bioavailable HIV-1 integrase inhibitors.

Fabrizio Fiore, Michael Rowley, Cristina Gardelli, 2008, Journal of medicinal chemistry.

Nonpeptidic Vinyl and Allyl Phosphonates as Falcipain‐2 Inhibitors

T. Schirmeister, E. Nizi, M. Zappalà, 2008, ChemMedChem.

Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACs.

S. Harper, S. Altamura, N. Gennari, 2016, ACS medicinal chemistry letters.