M. Ferrara

发表

Discovery of raltegravir, a potent, selective orally bioavailable HIV-integrase inhibitor for the treatment of HIV-AIDS infection.

D. Hazuda, M. Rowley, V. Summa, 2008, Journal of medicinal chemistry.

MK-5172, a Selective Inhibitor of Hepatitis C Virus NS3/4a Protease with Broad Activity across Genotypes and Resistant Variants

Adam T. Gates, D. Hazuda, M. Rudd, 2012, Antimicrobial Agents and Chemotherapy.

Discovery of (7R)-14-cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylic acid (MK-3281), a potent and orally bioavailable finger-loop inhibitor of the hepatitis C virus NS5B polymerase.

U. Koch, R. De Francesco, P. Baiocco, 2011, Journal of medicinal chemistry.

Allosteric inhibitors of hepatitis C virus NS5B polymerase thumb domain site II: structure-based design and synthesis of new templates.

U. Koch, M. Rowley, V. Summa, 2010, Bioorganic & medicinal chemistry.

The metabolism and disposition of a potent inhibitor of hepatitis C virus NS3/4A protease

X. Chu, R. Evers, S. Harper, 2010, Xenobiotica; the fate of foreign compounds in biological systems.

Discovery of MK-5172, a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor.

M. Rudd, P. Coleman, S. Harper, 2012, ACS medicinal chemistry letters.

Discovery of BI-2545: A Novel Autotaxin Inhibitor That Significantly Reduces LPA Levels in Vivo.

P. Nicklin, G. Roth, M. Ferrara, 2017, ACS medicinal chemistry letters.

Application of Chiral Sulfides to Catalytic Asymmetric Aziridination and Cyclopropanation with In Situ Generation of the Diazo Compound.

G. Hynd, M. Porcelloni, M. Ferrara, 2001, Angewandte Chemie.

Intramolecular Cycloaddition/Rearrangement of Alkylidenecyclopropane Nitrones from Palladium(0)‐Catalyzed Alkylation of Amino Acid Derivatives

M. Ferrara, A. Brandi, F. M. Cordero, 1999 .

Thiophilic allylation of dithioesters and trithiocarbonates

A. Degl'innocenti, A. Capperucci, M. Ferrara, 1994 .

P2‐Quinazolinones and Bis‐Macrocycles as New Templates for Next‐Generation Hepatitis C Virus NS3/4a Protease Inhibitors: Discovery of MK‐2748 and MK‐6325

Qian Huang, Adam T. Gates, M. Rudd, 2015, ChemMedChem.

Discovery and synthesis of HIV integrase inhibitors: development of potent and orally bioavailable N-methyl pyrimidones.

Michael Rowley, Cristina Gardelli, Marco Ferrara, 2007, Journal of medicinal chemistry.

Highly diastereoselective aziridination of imines with trimethylsilyldiazomethane. Subsequent silyl substitution with electrophiles, ring opening, and metalation of C-silylaziridines--a cornucopia of highly selective transformations.

M. Ferrara, V. Aggarwal, S. E. Spey, 2002, The Journal of organic chemistry.

Scope and limitations in sulfur ylide mediated catalytic asymmetric aziridination of imines: use of phenyldiazomethane, diazoesters and diazoacetamides

R. Fieldhouse, M. Ferrara, V. Aggarwal, 2001 .

Enantioselective Synthesis of the Cyclopiazonic Acid Family Using Sulfur Ylides

M. Ferrara, M. Shaw, Mark R. Crimmin, 2018, Angewandte Chemie.

[2,3]-Sigmatropic rearrangement of allylic sulfur ylides derived from trimethylsilyldiazomethane (TMSD)

M. Ferrara, V. Aggarwal, S. E. Spey, 1999 .

Inhibitors of the hepatitis C virus NS3 protease with basic amine functionality at the P3-amino acid N-terminus: discovery and optimization of a new series of P2-P4 macrocycles.

S. Harper, N. Liverton, U. Koch, 2009, Journal of medicinal chemistry.

Fluoride Ion Induced Thiophilic Addition of Allylsilanes to Thioketones

A. Degl'innocenti, A. Capperucci, M. Ferrara, 1992 .

Identification of Highly Selective Orexin 1 Receptor Antagonists Driven by Structure-Based Design

Roland Pfau, Uta Lessel, Marco Ferrara, 2021, J. Chem. Inf. Model..

Fluoride Ion Promoted Reactivity of Thiocarbonyl Containing Molecules with Silyl Derivatives: A Novel Access to Allyl Sulfides

A. Degl'innocenti, A. Capperucci, M. Ferrara, 2010 .

MK-5172, a Selective Inhibitor of Hepatitis C Virus NS3/4a Protease with Broad Activity across Genotypes and Resistant Variants

Qian Huang, Adam T. Gates, D. Hazuda, 2014, Antimicrobial Agents and Chemotherapy.

Design and synthesis of bicyclic pyrimidinones as potent and orally bioavailable HIV-1 integrase inhibitors.

Fabrizio Fiore, Michael Rowley, Cristina Gardelli, 2008, Journal of medicinal chemistry.

Application of Chiral Sulfides to Catalytic Asymmetric Aziridination and Cyclopropanation with In Situ Generation of the Diazo Compound.

G. Hynd, M. Porcelloni, M. Ferrara, 2001, Angewandte Chemie.