Giovanna Pescatore

发表

Discovery of raltegravir, a potent, selective orally bioavailable HIV-integrase inhibitor for the treatment of HIV-AIDS infection.

D. Hazuda, M. Rowley, V. Summa, 2008, Journal of medicinal chemistry.

Tetrazole thioacetanilides: potent non-nucleoside inhibitors of WT HIV reverse transcriptase and its K103N mutant.

Michael Rowley, Michael D. Miller, M. Rowley, 2006, Bioorganic & medicinal chemistry letters.

Discovery of a potent class I selective ketone histone deacetylase inhibitor with antitumor activity in vivo and optimized pharmacokinetic properties.

M. Rowley, Philip Jones, C. Steinkühler, 2009, Journal of medicinal chemistry.

A novel series of potent and selective ketone histone deacetylase inhibitors with antitumor activity in vivo.

R. De Francesco, S. Altamura, M. Rowley, 2008, Journal of medicinal chemistry.

Optimization of a series of potent and selective ketone histone deacetylase inhibitors.

M. Rowley, Philip Jones, C. Steinkühler, 2008, Bioorganic & medicinal chemistry letters.

Tetrazole thioacetanilides: potent non-nucleoside inhibitors of WT HIV reverse transcriptase and its K103N mutant.

M. Rowley, V. Summa, R. Laufer, 2006, Bioorganic & medicinal chemistry letters.

A novel base-mediated intramolecular hydroamination to build fused heteroaryl pyrazinones

O. Kinzel, Giovanna Pescatore, Philip Jones, 2009 .

Discovery and synthesis of HIV integrase inhibitors: development of potent and orally bioavailable N-methyl pyrimidones.

Michael Rowley, Cristina Gardelli, Marco Ferrara, 2007, Journal of medicinal chemistry.

A study on the chelation control in the regioselective opening of 2,3-bifunctionalized epoxides

G. Righi, Giovanna Pescatore, F. Bonadies, 2001 .

New stereoselective synthesis of the peptidic aminopeptidase inhibitors bestatin, phebestin and probestin

G. Righi, Giovanna Pescatore, C. Bonini, 2003 .

Identification and SAR of novel pyrrolo[1,2-a]pyrazin-1(2H)-one derivatives as inhibitors of poly(ADP-ribose) polymerase-1 (PARP-1).

C. Toniatti, M. Rowley, Philip Jones, 2010, Bioorganic & medicinal chemistry letters.

Dihydroxy-pyrimidine and N-methylpyrimidone HIV-integrase inhibitors: improving cell based activity by the quaternarization of a chiral center.

V. Summa, E. Muraglia, M. Orsale, 2009, Bioorganic & Medicinal Chemistry Letters.

Design and synthesis of bicyclic pyrimidinones as potent and orally bioavailable HIV-1 integrase inhibitors.

Fabrizio Fiore, Michael Rowley, Cristina Gardelli, 2008, Journal of medicinal chemistry.