J. Chen

发表

Characterization of transcriptional regulatory domains of ankyrin repeat cofactor-1.

Chia-Wei Li, A. Zhang, J. Chen, 2007, Biochemical and biophysical research communications.

Daxx contains two nuclear localization signals and interacts with importin α3

A. Zhang, Shih-Chieh Tsai, Liuh-Yow Chen, 2008 .

PML and the oncogenic nuclear domains in regulating transcriptional repression.

H. Li, J. Chen, Hui Li, 2000, Current opinion in cell biology.

RAC 3 , a steroid y nuclear receptor-associated coactivator that is related to SRC-1 and TIF 2

J. Chen, P. J. Gomes, Ligia-Ancuta Hui, 1997 .

Promyelocytic leukemia nuclear bodies support a late step in DNA double‐strand break repair by homologous recombination

Zhanna Hakhverdyan, N. Denissova, Cara Nasello, 2012, Journal of cellular biochemistry.

Regulation and Binding of Pregnane X Receptor by Nuclear Receptor Corepressor Silencing Mediator of Retinoid and Thyroid Hormone Receptors (SMRT)

J. C. Ghosh, Liuh-Yow Chen, J. Chen, 2006, Molecular Pharmacology.

Regulation and Binding of Pregnane X Receptor by Nuclear Receptor Corepressor SMRT

J. C. Ghosh, Liuh-Yow Chen, J. Chen, 2005 .

Preferential Physical and Functional Interaction of Pregnane X Receptor with the SMRTα Isoform

J. Chen, Chia‐Wei Li, Gia Khanh Dinh, 2009, Molecular Pharmacology.

SMRTe, a silencing mediator for retinoid and thyroid hormone receptors-extended isoform that is more related to the nuclear receptor corepressor.

Hui Li, H. Li, L. Li, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Role of Retinoid Receptor Coactivator Pockets in Cofactor Recruitment and Transcriptional Regulation*

Hui Li, Xiaofang Yang, Jilin Liu, 2001, The Journal of Biological Chemistry.

Coactivation and corepression in transcriptional regulation by steroid/nuclear hormone receptors.

H. Li, J. Chen, Hui Li, 1998, Critical reviews in eukaryotic gene expression.

Evidence of a retinoid signaling alteration involving the activator protein 1 complex in tumorigenic human bronchial epithelial cells and non-small cell lung cancer cells.

W. Hong, J. Kurie, M. Dawson, 1997, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Conserved DNA binding and self-association domains of the Drosophila zeste protein

V. Pirrotta, J. Chen, C. S. Chan, 1992, Molecular and cellular biology.

The ThioredoxinT and deadhead gene pair encode testis- and ovary-specific thioredoxins in Drosophila melanogaster

Malin J. Svensson, V. Pirrotta, J. Larsson, 2003, Chromosoma.

Characterization of a Novel Small Molecule Subtype Specific Estrogen-Related Receptor α Antagonist in MCF-7 Breast Cancer Cells

H. Wilkinson, J. Chen, M. Cunningham, 2009, PloS one.

A transcriptional co-repressor that interacts with nuclear hormone receptors

R. Evans, J. Chen, R. Evans, 1995, Nature.

The Receptor-associated Coactivator 3 Activates Transcription through CREB-binding Protein Recruitment and Autoregulation*

Hui Li, J. Chen, J. Chen, 1998, The Journal of Biological Chemistry.

J. Chrivia, J. Chen, M. A. Monroy, 2003, Molecular endocrinology.

The SRC family of nuclear receptor coactivators.

J. Chen, C. Leo, J. Chen, 2000, Gene.

RAC3, a steroid/nuclear receptor-associated coactivator that is related to SRC-1 and TIF2.

Hui Li, H. Li, J. Chen, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Sequestration and Inhibition of Daxx-Mediated Transcriptional Repression by PML

Jennifer O'Neil, Hui Li, J. O'neil, 2000, Molecular and Cellular Biology.

TITLE: The Regulation and Function of Nuclear Receptor Corepressor SMRT in Human Breast Cancer Cells PRINCIPAL INVESTIGATOR: Christopher Leo

J. Chen, C. Leo, 2022 .

Painting of fourth, a chromosome-specific protein in Drosophila

V. Pirrotta, J. Larsson, V. Rasheva, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Activation and binding of peroxisome proliferator-activated receptor gamma by synthetic cannabinoid ajulemic acid.

Hui Li, Jilin Liu, J. Chen, 2003, Molecular pharmacology.

Daxx Silencing Sensitizes Cells to Multiple Apoptotic Pathways

Liuh-Yow Chen, J. Chen, J. Don Chen, 2003, Molecular and Cellular Biology.

The t(5;17) acute promyelocytic leukemia fusion protein NPM-RAR interacts with co-repressor and co-activator proteins and exhibits both positive and negative transcriptional properties.

Hui Li, H. Li, J. Chen, 2000, Blood.

Identification of a Novel Family of Ankyrin Repeats Containing Cofactors for p160 Nuclear Receptor Coactivators*

A. Zhang, Shih-Chieh Tsai, Hui Li, 2004, Journal of Biological Chemistry.

The Human Homologue of the Yeast DNA Repair and TFIIH Regulator MMS19 Is an AF-1-specific Coactivator of Estrogen Receptor*

Hui Li, J. Chen, Xiaoyang Wu, 2001, The Journal of Biological Chemistry.

Differential Mechanisms of Nuclear Receptor Regulation by Receptor-associated Coactivator 3*

Hui Li, J. Chen, C. Leo, 2000, The Journal of Biological Chemistry.

Identification of ANKRD11 as a p53 coactivator

P. Neilsen, D. Callen, R. Schulz, 2008, Journal of Cell Science.

Award Number: W81XWH-08-1-0143 TITLE: Obstructing Androgen Receptor Activation in Prostate Cancer Cells Through Post-translational Modification by NEDD8

Principal Investigator, J. Chen, Robert Wood Johnson, 2011 .

Human ADA3 regulates RARα transcriptional activity through direct contact between LxxLL motifs and the receptor coactivator pocket

W. Welsh, Ni Ai, J. Chen, 2010, Nucleic acids research.

Huntingtin Is Present in the Nucleus, Interacts with the Transcriptional Corepressor C-terminal Binding Protein, and Represses Transcription*

J. Nevins, Z. Qin, N. Aronin, 2002, The Journal of Biological Chemistry.

Ankyrin repeats-containing cofactors interact with ADA3 and modulate its co-activator function.

A. Zhang, J. Chen, Chia‐Wei Li, 2008, The Biochemical journal.

Structural Model Reveals Key Interactions in the Assembly of the Pregnane X Receptor/Corepressor Complex

W. Welsh, J. Chen, Chia‐Wei Li, 2006, Molecular Pharmacology.

Steroid/nuclear receptor coactivators.

J. Chen, J.Don Chen, 2000, Vitamins and hormones.

Human Slug Is a Repressor That Localizes to Sites of Active Transcription

Y. Ip, S. Guru, J. Chen, 2000, Molecular and Cellular Biology.

Regulation of Androgen Receptor Activity by the Nuclear Receptor Corepressor SMRT*

J. C. Ghosh, A. Zhang, F. Xia, 2003, The Journal of Biological Chemistry.

Coactivator/corepressor ratios modulate PR-mediated transcription by the selective receptor modulator RU486

B. O’Malley, M. Tsai, J. Wong, 2002, Proceedings of the National Academy of Sciences of the United States of America.

The nuclear cofactor RAC3/AIB1/SRC-3 enhances Nrf2 signaling by interacting with transactivation domains

A. Kong, Jung-Hwan Kim, J. Chen, 2012, Oncogene.

Characterization of receptor interaction and transcriptional repression by the corepressor SMRT.

Hui Li, H. Li, J. Chen, 1997, Molecular endocrinology.

The nuclear receptor corepressor SMRT inhibits interstitial collagenase (MMP-1) transcription through an HRE-independent mechanism.

C. Brinckerhoff, M. Vincenti, J. Chen, 1997, Biochemical and biophysical research communications.

SMRT isoforms mediate repression and anti-repression of nuclear receptor heterodimers.

K. Umesono, Jasmine Chen, R. Evans, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Interactions that determine the assembly of a retinoid X receptor/corepressor complex

M. Lambert, H. Xu, J. C. Ghosh, 2002, Proceedings of the National Academy of Sciences of the United States of America.

H. Wilkinson, J. Chen, M. Chisamore, 2009, Molecular Cancer Therapeutics.

Regulation of Nrf2 transactivation domain activity by p160 RAC3/SRC3 and other nuclear co-regulators.

A. Kong, A. Zhang, M. Jain, 2006, Journal of biochemistry and molecular biology.

Nuclear localization of coactivator RAC3 is mediated by a bipartite NLS and importin alpha3.

A. Zhang, J. Chen, P. Yeung, 2006, Biochemical and biophysical research communications.

Subcellular localization of ankyrin repeats cofactor‐1 regulates its corepressor activity

A. Zhang, Shih-Chieh Tsai, J. Chen, 2007, Journal of cellular biochemistry.

The Major Human Pregnane X Receptor (PXR) Splice Variant, PXR.2, Exhibits Significantly Diminished Ligand-Activated Transcriptional Regulation

S. Ekins, W. Welsh, V. Kholodovych, 2009, Drug Metabolism and Disposition.

NuRD complex component Mi-2 binds to and represses ROR?-mediated transcriptional activation

F. Xia, J. Chen, D. Johnson, 2004 .

NuRD complex component Mi-2beta binds to and represses RORgamma-mediated transcriptional activation.

F. Xia, J. Chen, Davidr . Johnson, 2004, Biochemical and biophysical research communications.

SMRTe Inhibits MEF2C Transcriptional Activation by Targeting HDAC4 and 5 to Nuclear Domains*

Hui Li, J. Chen, Xiaoyang Wu, 2001, The Journal of Biological Chemistry.

Daxx contains two nuclear localization signals and interacts with importin alpha3.

A. Zhang, Shih-Chieh Tsai, Liuh-Yow Chen, 2008, Journal of cellular biochemistry.

Regulation of Xenobiotic Sensor PXR and AhR by NF-κB and Its Roles in Xenobiotic Detoxification and Inflammation-Associated Carcinogenesis

M. Gallo, N. Ouyang, J. Chen, 2010 .

Identification of small molecule estrogen‐related receptor α–specific antagonists and homology modeling to predict the molecular determinants as the basis for selectivity over ERRβ and ERRγ

Gregory T O'Donnell, H. Wilkinson, J. Schaeffer, 2008 .