B. E. van den Akker

发表

Genetic characterization of mesenchymal, clear cell, and dedifferentiated chondrosarcoma

P. Picci, D. de Jong, J. Bovée, 2012, Genes, chromosomes & cancer.

NAD Synthesis Pathway Interference Is a Viable Therapeutic Strategy for Chondrosarcoma

A. Cleton-Jansen, E. Danen, J. Bovée, 2017, Molecular Cancer Research.

Transforming Growth Factor β Signaling in Colorectal Cancer Cells With Microsatellite Instability Despite Biallelic Mutations in TGFBR2

M. V. Dinther, H. Morreau, T. van Wezel, 2015 .

Screening for potential targets for therapy in mesenchymal, clear cell, and dedifferentiated chondrosarcoma reveals Bcl-2 family members and TGFβ as potential targets.

A. Flanagan, P. Picci, P. Hogendoorn, 2013, The American journal of pathology.

The activities of Smad and Gli mediated signalling pathways in high-grade conventional osteosarcoma.

A. Cleton-Jansen, P. Hogendoorn, P. ten Dijke, 2012, European journal of cancer.

Targeting the NAD Salvage Synthesis Pathway as a Novel Therapeutic Strategy for Osteosarcomas with Low NAPRT Expression

A. Cleton-Jansen, A. Kruisselbrink, J. Bovée, 2021, International journal of molecular sciences.

COX-2 expression in chondrosarcoma: a role for celecoxib treatment?

A. Llombart‐Bosch, A. Taminiau, J. Bovée, 2010, European journal of cancer.

Human papillomavirus type 18 and other risk factors for cervical cancer in Jakarta, Indonesia

G. Fleuren, B. E. van den Akker, M. D. De Boer, 2006, International Journal of Gynecologic Cancer.

Prevalence of human papillomavirus in Indonesia: a population-based study in three regions

G. Fleuren, Lisnawati, B. E. van den Akker, 2008, British Journal of Cancer.

Delta-Like Ligand–Notch1 Signaling Is Selectively Modulated by HPV16 E6 to Promote Squamous Cell Proliferation and Correlates with Cervical Cancer Prognosis

G. Kenter, R. D. de Menezes, J. Doorbar, 2021, Cancer Research.

Inhibition of Bcl-2 family members sensitises soft tissue leiomyosarcomas to chemotherapy

J. Fletcher, F. Chibon, J. Coindre, 2016, British Journal of Cancer.

Expanding the Spectrum of EWSR1-NFATC2-rearranged Benign Tumors

A. Cleton-Jansen, D. Baumhoer, J. Bovée, 2021, The American journal of surgical pathology.

Circulating human papillomavirus type 16 specific T‐cells are associated with HLA Class I expression on tumor cells, but not related to the amount of viral oncogene transcripts

S. H. van der Burg, E. Jordanova, G. Fleuren, 2007, International journal of cancer.

Bcl-xl as the most promising Bcl-2 family member in targeted treatment of chondrosarcoma

J. Blay, J. Bovée, B. E. van den Akker, 2018, Oncogenesis.

Kinome and mRNA expression profiling of high-grade osteosarcoma cell lines implies Akt signaling as possible target for therapy

A. Cleton-Jansen, P. Hogendoorn, M. Serra, 2014, BMC Medical Genomics.

Osteosarcoma Stem Cells Have Active Wnt/β‐catenin and Overexpress SOX2 and KLF4

Anne-Marie Cleton-Jansen, A. Cleton-Jansen, C. Gomes, 2016, Journal of cellular physiology.

Distinct Patterns of Somatic Mosaicism in the APC Gene in Neoplasms From Patients With Unexplained Adenomatous Polyposis.

W. Dinjens, H. Morreau, T. van Wezel, 2017, Gastroenterology.

Does PARP Inhibition Sensitize Chondrosarcoma Cell Lines to Chemotherapy or Radiotherapy? Results From a Three-dimensional Spheroid Cell Model

J. Bovée, B. E. van den Akker, I. B. Briaire-de Bruijn, 2022, Clinical orthopaedics and related research.

Whole Gene Capture Analysis of 15 CRC Susceptibility Genes in Suspected Lynch Syndrome Patients

P. Devilee, A. Wagner, H. Morreau, 2016, PloS one.

Combined mismatch repair and POLE/POLD1 defects explain unresolved suspected Lynch syndrome cancers

P. Devilee, A. Wagner, H. Morreau, 2015, European Journal of Human Genetics.

Germline variants in POLE are associated with early onset mismatch repair deficient colorectal cancer

H. Morreau, T. van Wezel, M. Ligtenberg, 2014, European Journal of Human Genetics.

IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma

Anne-Marie Cleton-Jansen, Ola Myklebost, Marieke L Kuijjer, 2013, BMC Cancer.

BMP and TGFbeta pathways in human central chondrosarcoma: enhanced endoglin and Smad 1 signaling in high grade tumors

A. Cleton-Jansen, W. Richter, J. Bovée, 2012, BMC Cancer.

Extreme Diversity of the Human Vascular Mesenchymal Cell Landscape

J. Hamming, J. Lindeman, B. E. van den Akker, 2020, Journal of the American Heart Association.

Selection of Effective Therapies Using Three-Dimensional in vitro Modeling of Chondrosarcoma

H. Gelderblom, J. Bovée, B. E. van den Akker, 2020, Frontiers in Molecular Biosciences.

Targeting glutaminolysis in chondrosarcoma in context of the IDH1/2 mutation

A. Cleton-Jansen, A. Kruisselbrink, J. Bovée, 2018, British Journal of Cancer.

R132C IDH1 mutations are found in spindle cell hemangiomas and not in other vascular tumors or malformations.

R. Sciot, A. Lazar, C. Fletcher, 2013, American Journal of Pathology.

Transforming Growth Factor β Signaling in Colorectal Cancer Cells With Microsatellite Instability Despite Biallelic Mutations in TGFBR2.

M. V. Dinther, H. Morreau, T. van Wezel, 2015, Gastroenterology.

Histological response to radiotherapy is an early event in myxoid liposarcoma

R. Haas, J. Bovée, B. E. van den Akker, 2023, Virchows Archiv.

BMP and TGFbeta pathways in human central chondrosarcoma: enhanced endoglin and Smad 1 signaling in high grade tumors

A. Cleton-Jansen, W. Richter, J. Bovée, 2012, BMC Cancer.

Osteosarcoma Stem Cells Have Active Wnt/β‐catenin and Overexpress SOX2 and KLF4

A. Cleton-Jansen, C. Gomes, J. Bovée, 2016, Journal of cellular physiology.

Multimodal profiling of chordoma immunity reveals distinct immune contextures

R. van der Breggen, W. Peul, J. Bovée, 2023, Journal for ImmunoTherapy of Cancer.