C. Carrera

发表

Homozygous deletions of methylthioadenosine phosphorylase (MTAP) are more frequent than p16INK4A (CDKN2) homozygous deletions in primary non-small cell lung cancers (NSCLC)

D. Carson, M. Schmid, D. Malicki, 1998, Oncogene.

The methylthioadenosine phosphorylase gene is frequently co‐deleted with the p16INK4a gene in acute type adult T‐cell leukemia

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 1998, International journal of cancer.

Methylthioadenosine Phosphorylase eDNA Transfection Alters Sensitivity to Depletion of Purine and Methionine in A 549 Lung Cancer Cells '

P. Tran, D. Carson, M. Rosenbach, 2022 .

Potent toxicity of 2-chlorodeoxyadenosine toward human monocytes in vitro and in vivo. A novel approach to immunosuppressive therapy.

D. Carson, L. Piro, E. Beutler, 1990, The Journal of clinical investigation.

DNA strand breaks, NAD metabolism, and programmed cell death.

D. Carson, C. Carrera, S. Seto, 1986, Experimental cell research.

Use of alanosine as a methylthioadenosine phosphorylase-selective therapy for T-cell acute lymphoblastic leukemia in vitro.

M. Amylon, M. Omura-Minamisawa, M. Diccianni, 1999, Cancer research.

Assignment of the gene for methylthioadenosine phosphorylase to human chromosome 9 by mouse-human somatic cell hybridization.

R. Eddy, T. Shows, D. Carson, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Purine metabolism of lymphocytes. Targets for chemotherapy drug development.

A. Saven, L. Piro, C. Carrera, 1994, Hematology/oncology clinics of North America.

Inhibition of DNA repair by deoxyadenosine in resting human lymphocytes.

D. Carson, C. Carrera, S. Seto, 1986, Journal of immunology.

Indanocine, a microtubule-binding indanone and a selective inducer of apoptosis in multidrug-resistant cancer cells.

H. Cottam, D. Carson, E. Hamel, 2000, Journal of the National Cancer Institute.

Metabolism and anti-human immunodeficiency virus-1 activity of 2-halo-2',3'-dideoxyadenosine derivatives.

D. Richman, D. Carson, T. Haertlé, 1988, The Journal of biological chemistry.

Lasting remissions in hairy-cell leukemia induced by a single infusion of 2-chlorodeoxyadenosine.

D. Carson, L. Piro, E. Beutler, 1990, The New England journal of medicine.

2-Chlorodeoxyadenosine chemotherapy triggers programmed cell death in normal and malignant lymphocytes.

A. Saven, D. Carson, L. Piro, 1991, Advances in experimental medicine and biology.

Oral antilymphocyte activity and induction of apoptosis by 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine.

T. Kipps, H. Cottam, D. Carson, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Nucleotide Requirements for the in Vitro Activation of the Apoptosis Protein-activating Factor-1-mediated Caspase Pathway*

Xiaodong Wang, W. Plunkett, H. Cottam, 2000, The Journal of Biological Chemistry.

Induction of an apoptotic program in cell-free extracts by 2-chloro-2'-deoxyadenosine 5'-triphosphate and cytochrome c.

Xiaodong Wang, X. Wang, H. Cottam, 1998, Proceedings of the National Academy of Sciences of the United States of America.

EFA (9-beta-D-erythrofuranosyladenine) is an effective salvage agent for methylthioadenosine phosphorylase-selective therapy of T-cell acute lymphoblastic leukemia with L-alanosine.

M. Diccianni, A. Batova, A. Yu, 2006, Blood.

Presence of methylthioadenosine phosphorylase (MTAP) in hematopoietic stem/progenitor cells: its therapeutic implication for MTAP (-) malignancies.

A. Batova, J. Yu, A. Yu, 1997, Clinical cancer research : an official journal of the American Association for Cancer Research.

2-Chlorodeoxyadenosine treatment of low-grade lymphomas.

A. Saven, D. Carson, L. Piro, 1992, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

2-Chlorodeoxyadenosine: an effective new agent for the treatment of chronic lymphocytic leukemia.

D. Carson, L. Piro, E. Beutler, 1988, Blood.

2-Chlorodeoxyadenosine: an effective new agent for the treatment of chronic lymphocytic leukemia.

D. Carson, L. Piro, E. Beutler, 1988, Blood.

Uptake and metabolism of daunorubicin by human leukemia cells

C. Carrera, J. Klock, J. Wilbur, 1982, Cancer Chemotherapy and Pharmacology.

Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes.

D. Carson, C. Carrera, M. Kubota, 1985, The Journal of clinical investigation.

Methylthioadenosine (MeSAdo) phosphorylase deficiency in malignancy.

H. Yamanaka, D. Carson, T. Nobori, 1988, Advances in experimental medicine and biology.

Regulation of S-Adenosylmethionine and Methylthioadenosine Metabolism in Methylthioadenosine Phosphorylase Deficient Malignant Cells

H. Yamanaka, J. Montgomery, D. Carson, 1986 .

Programmed cell death and adenine deoxynucleotide metabolism in human lymphocytes.

H. Yamanaka, D. Carson, C. Carrera, 1988, Advances in enzyme regulation.

2-Chlorodeoxyadenosine (2-CdA): A Potent Chemotherapeutic and Immunosuppressive Nucleoside.

A. Saven, D. Carson, L. Piro, 1991, Leukemia & lymphoma.

2-Chlorodeoxyadenosine Treatment of Refractory Chronic Lymphocytic Leukemia.

A. Saven, D. Carson, L. Piro, 1991, Leukemia & lymphoma.

2-halo-2',3'-dideoxyadenosines: metabolically stable dideoxynucleosides with activity against the human immunodeficiency virus (HIV).

E. H. Willis, D. Richman, D. Carson, 1989, Advances in experimental medicine and biology.

Oral 2-chlorodeoxyadenosine in psoriatic

M. Weisman, D. Carson, D. Piacquadio, 1995 .

Rational design, synthesis and structure-activity relationships of antitumor (E)-2-benzylidene-1-tetralones and (E)-2-benzylidene-1-indanones.

H. Cottam, D. Carson, C. Carrera, 2000, Bioorganic & medicinal chemistry letters.

Hairy cell leukemia: new understanding of biology and treatment.

A. Saven, D. Carson, L. Piro, 1993, Cancer treatment and research.

Dependence of cell survival on DNA repair in human mononuclear phagocytes.

D. Carson, C. Carrera, C. Terai, 1991, Journal of immunology.

Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria.

D. Rose, H. Cottam, D. Carson, 2000, Blood.

Deoxynucleoside overproduction in deoxyadenosine-resistant, adenosine deaminase-deficient human histiocytic lymphoma cells.

D. Carson, C. Carrera, M. Kubota, 1984, Biochimica et biophysica acta.

Resistance to multiple adenine nucleoside and methionine analogues in mutant murine lymphoma cells with enlarged S-adenosylmethionine pools.

J. Montgomery, D. Carson, C. Carrera, 1986, Cancer research.

Methylthioadenosine phosphorylase cDNA transfection alters sensitivity to depletion of purine and methionine in A549 lung cancer cells.

P. Tran, D. Carson, T. Nobori, 1996, Cancer research.

Quantitative immunoassay of human deoxycytidine kinase in malignant cells.

D. Carson, C. Carrera, H. Kawasaki, 1992, Analytical biochemistry.

Deoxyadenosine-resistant human T lymphoblasts with elevated 5'-nucleotidase activity.

D. Carson, C. Carrera, T. Iizasa, 1991, Biochimica et biophysica acta.

Relationship of deoxycytidine kinase and cytoplasmic 5'-nucleotidase to the chemotherapeutic efficacy of 2-chlorodeoxyadenosine.

T. Kipps, A. Saven, D. Carson, 1993, Blood.

A methylthioadenosine phosphorylase (MTAP) fusion transcript identifies a new gene on chromosome 9p21 that is frequently deleted in cancer

D. Carson, M. Schmid, M. Rosenbach, 2000, Oncogene.

2-Chlorodeoxyadenosine: an active agent in the treatment of cutaneous T-cell lymphoma.

A. Saven, D. Carson, L. Piro, 1992, Blood.

The Mitogenic Principle of Escherichia coli Lipoprotein: Synthesis, Spectroscopic Characterization, and Mitogenicity of N-Palmitoyl-S-[(2R,)-2,3-dipalmitoyloxypropyl]-(R)-cysteine Methyl Ester

W. Bessler, H. Brückner, G. Jung, 1983 .

Metabolic Basis for Immune Dysfunction in Adenosine Deaminase Deficiency a

D. Carson, C. Carrera, M. Kubota, 1985, Annals of the New York Academy of Sciences.

affecting the mitochondria lymphocytic leukemia cells by damaging the DNA and by directly Deoxyadenosine analogs induce programmed cell death in chronic

D. Rose, H. Cottam, D. Carson, 2013 .

Regional myocardial dynamics from single-plane coronary cineangiograms.

G. Daughters, N. B. Ingels, C. Carrera, 1973, Journal of biomechanics.

Activity of 2-chloro-2'-deoxyadenosine in chronic lymphocytic leukemia, hairy cell leukemia, and autoimmune hemolytic anemia.

D. Carson, L. Piro, E. Beutler, 1989, Advances in experimental medicine and biology.

Effect of Antidepressant Switching vs Augmentation on Remission Among Patients With Major Depressive Disorder Unresponsive to Antidepressant Treatment: The VAST-D Randomized Clinical Trial

Grant D. Huang, M. Thase, T. Suppes, 2017, JAMA.

Marrow suppression produced by repeated doses of cladribine.

J. Koziol, E. Beutler, C. Carrera, 1994, Acta haematologica.

Biochemical basis for deoxyadenosine and 2-chlorodeoxyadenosine toxicity to resting human lymphocytes.

D. Carson, C. Carrera, S. Seto, 1986 .

5'-deoxy-5'-methylthioadenosine phosphorylase deficiency in leukemia: genetics and biochemical aspects.

D. Carson, C. Carrera, M. Kubota, 1986, Advances in experimental medicine and biology.

Cellular and plasma kinetics of daunorubicin given by two methods of administration in a patient with acute leukemia.

C. Pegelow, C. Carrera, J. Klock, 1982, Cancer treatment reports.

2-Chlorodeoxyadenosine dose escalation in nonhematologic malignancies.

A. Saven, T. Waltz, D. Carson, 1993, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Profound toxicity of deoxyadenosine and 2-chlorodeoxyadenosine toward human monocytes in vitro and in vivo.

H. Yamanaka, D. Carson, L. Piro, 1989, Advances in experimental medicine and biology.

Pivotal Role of Poly(ADP-Ribose) Polymerase Activation in the Pathogenesis of Immunodeficiency and in the Therapy of Chronic Lymphocytic Leukemia

D. Carson, L. Piro, E. Beutler, 1989 .

Immunodeficiency secondary to adenosine deaminase deficiency and purine nucleoside phosphorylation deficiency.

D. Carson, C. Carrera, 1990, Seminars in hematology.

2-Chlorodeoxyadenosine: an active agent in the treatment of cutaneous T-cell lymphoma.

A. Saven, D. Carson, L. Piro, 1992, Blood.