S. Takeuchi

发表

Identification of three distinct regions of deletion on the long arm of chromosome 11 in childhood acute lymphoblastic leukemia

M. Schrappe, C. Bartram, H. Koeffler, 1999, Oncogene.

Methylation analysis of the adenomatous polyposis coli (APC) gene in adult T-cell leukemia/lymphoma.

H. Koeffler, Yang Yang, H. Taguchi, 2006, Leukemia research.

Long-term study of the clinical significance of loss of heterozygosity in childhood acute lymphoblastic leukemia

M. Schrappe, H. Koeffler, H. Taguchi, 2003, Leukemia.

Acute lymphoblastic leukemia of childhood: identification of two distinct regions of deletion on the short arm of chromosome 12 in the region of TEL and KIP1.

M. Schrappe, C. Bartram, H. Koeffler, 1996, Blood.

Tumor necrosis factor alpha polymorphism associated with increased susceptibility to development of adult T-cell leukemia/lymphoma in human T-lymphotropic virus type 1 carriers.

M. Tomonaga, H. Koeffler, C. Miller, 2001, Cancer research.

Mutation Found in Breast Cancer 1

H. Koeffler, K. Spirin, N. Kawamata, 2006 .

Allelic loss during progression of follicular lymphoma.

S. de Vos, T. Grogan, H. Koeffler, 2004, Leukemia research.

Frequent Loss of Heterozygosity on Chromosomes 6q, 9p, 11q or 12p in Childhood Acute Lymphoblastic Leukemia

Carl W. Miller, T. Golub, D. Gilliland, 1998 .

Mutation and expression analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in pituitary tumors.

S. Melmed, H. Koeffler, I. Shimon, 1998, The Journal of endocrinology.

p27/Kipl Mutation Found in Breast Cancer1

H. Koeffler, N. Kawamata, J. Simpson, 1996 .

Allelotype analysis of childhood acute lymphoblastic leukemia.

C. Bartram, H. Koeffler, C. Miller, 1995, Cancer research.

Analysis of a family of cyclin-dependent kinase inhibitors: p15/MTS2/INK4B, p16/MTS1/INK4A, and p18 genes in acute lymphoblastic leukemia of childhood.

C. Bartram, A. Tobler, C. Miller, 1995, Blood.

Primary effusion lymphoma in women: report of two cases of Kaposi's sarcoma herpes virus-associated effusion-based lymphoma in human immunodeficiency virus-negative women.

S. de Vos, E. Cesarman, Jonathan, 1996, Blood.

Frequent loss of heterozygosity in region of the KIP1 locus in non-small cell lung cancer: evidence for a new tumor suppressor gene on the short arm of chromosome 12.

H. Koeffler, C. Miller, J. Slater, 1996, Cancer research.

Carriers Leukemia / Lymphoma in Human T-lymphotropic Virus Type 1 Increased Susceptibility to Development of Adult T-Cell Polymorphism Associated with α Tumor Necrosis Factor

Carl W. Miller, M. Tomonaga, H. Koeffler, 2001 .

Kaposi's sarcoma-associated herpesvirus (KSHV or HHV8) in primary effusion lymphoma: ultrastructural demonstration of herpesvirus in lymphoma cells.

S. de Vos, E. Cesarman, H. Koeffler, 1996, Blood.

Acute megakaryoblastic leukemia: establishment of a new cell line (MKPL-1) in vitro and in vivo.

Y. Ohtsuki, H. Taguchi, H. Enzan, 1992, Leukemia.

Establishment and characterization of a thymic carcinoma cell line (Ty‐82) carrying t(15;19)(ql5;p13) chromosome abnormality

Y. Ohtsuki, H. Sonobe, T. Takeuchi, 1992, International journal of cancer.

HIV-1 protease inhibitor ritonavir potentiates the effect of 1,25-dihydroxyvitamin D3 to induce growth arrest and differentiation of human myeloid leukemia cells via down-regulation of CYP24.

H. Koeffler, Yang Yang, T. Ikezoe, 2006, Leukemia research.

Methylation of the MLH1 gene in hematological malignancies.

H. Koeffler, Yang Yang, H. Taguchi, 2005, Oncology reports.

Ovarian Cancer: Loss of Heterozygosity Frequently Occurs in the ATM Gene, but Structural Alterations Do Not Occur in This Gene

J. Yokota, H. Koeffler, N. Tsuruoka, 1999, Oncology.

C/EBP-β, C/EBP-δ, PU.1, AML1 genes: mutational analysis in 381 samples of hematopoietic and solid malignancies

Carl W. Miller, W. Hofmann, H. Koeffler, 2002 .

C/EBP-beta, C/EBP-delta, PU.1, AML1 genes: mutational analysis in 381 samples of hematopoietic and solid malignancies.

Carl W. Miller, W. Hofmann, H. Koeffler, 2002, Leukemia research.

Aberrant methylation in promoter-associated CpG islands of multiple genes in relapsed childhood acute lymphoblastic leukemia.

J. V. van Dongen, C. Bartram, H. Koeffler, 2004, Oncology reports.

Aberrant methylation in promoter-associated CpG islands of multiple genes in therapy-related leukemia.

H. Koeffler, Yang Yang, S. Takeuchi, 2003, International journal of oncology.

Aberrant methylation in promoter-associated CpG islands of multiple genes in acute lymphoblastic leukemia.

J. V. van Dongen, C. Bartram, W. Hofmann, 2006, Leukemia research.

Alterations of the cyclin-dependent kinase inhibitor p19 (INK4D) is rare in hematopoietic malignancies.

M. Tomonaga, H. Koeffler, C. Miller, 1996, Leukemia.

Allelotype analysis in relapsed childhood acute lymphoblastic leukemia

C. Bartram, J. Dongen, H. Koeffler, 2003, Oncogene.

Genetic polymorphisms in the tumour necrosis factor locus in childhood acute lymphoblastic leukaemia

M. Schrappe, C. Bartram, H. Koeffler, 2002, British journal of haematology.

Comparative analysis of hypermethylation of cell cycle control and DNA-mismatch repair genes in low-density and CD34+ bone marrow cells from patients with myelodysplastic syndrome.

E. Thiel, H. Koeffler, S. Takeuchi, 2006, Leukemia research.

Methylation Analysis of Cell Cycle Control Genes in Adult T-Cell Leukemia/Lymphoma

W. Hofmann, H. Koeffler, K. Tsukasaki, 2001, Leukemia & lymphoma.

Loss of genomic imprinting of insulin-like growth factor 2 is strongly associated with cellular proliferation in normal hematopoietic cells.

W. Hofmann, H. Koeffler, S. Takeuchi, 2002, Experimental hematology.

The ATM gene and susceptibility to childhood T‐cell acute lymphoblastic leukaemia

C. Bartram, H. Koeffler, H. Taguchi, 1998, British journal of haematology.

Alterations of the p16 (MTS1) gene in testicular, ovarian, and endometrial malignancies.

S. Melmed, H. Koeffler, T. Strohmeyer, 1995, The Journal of urology.

TEL is one of the targets for deletion on 12p in many cases of childhood B-lineage acute lymphoblastic leukemia

D. Gilliland, H. Koeffler, A. Reiter, 1997, Leukemia.

TEL/AML-1 dimerizes and is associated with a favorable outcome in childhood acute lymphoblastic leukemia.

H P Koeffler, T. Golub, D. Neuberg, 1996, Blood.

Germline mutation of the p27/Kip1 gene in childhood acute lymphoblastic leukemia

H. Koeffler, T. Ikezoe, H. Taguchi, 2002, Leukemia.

SAHA, a HDAC inhibitor, has profound anti-growth activity against non-small cell lung cancer cells.

Carl W. Miller, N. Komatsu, N. Kawamata, 2006, Oncology reports.

Frequent loss of heterozygosity in the region of the D7S523 locus in advanced ovarian cancer

Carl W. Miller, J. Yokota, N. Tsuruoka, 1997, Genes, chromosomes & cancer.

Mutations in the gene encoding the transcription factor CCAAT/enhancer binding protein alpha in myelodysplastic syndromes and acute myeloid leukemias.

Carl W. Miller, W. Hofmann, H. Koeffler, 2002, Blood.

Molecular analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in human malignancies.

C. Bartram, H. Koeffler, D. Park, 1995, Cancer research.

MS-275, a novel histone deacetylase inhibitor with selectivity against HDAC1, induces degradation of FLT3 via inhibition of chaperone function of heat shock protein 90 in AML cells.

H. Koeffler, T. Ikezoe, Jing Yang, 2008, Leukemia research.

Analysis of K-ras Codon 12 Mutation in Flat and Nodular Variants of Serrated Adenoma in the Colon

S. Tamura, T. Tadokoro, Y. Higashidani, 2003, Diseases of the colon and rectum.

C/EBP-ε: Chromosomal mapping and mutational analysis of the gene in leukemia and preleukemia

A. Chumakov, H. Koeffler, N. Tsuruoka, 1997 .

Comparative genomic hybridization in childhood acute lymphoblastic leukemia: correlation with interphase cytogenetics and loss of heterozygosity analysis.

A. Jauch, B. Schoell, A. Teigler‐Schlegel, 2001, Cancer genetics and cytogenetics.

Homozygous Deletion of the p16 Gene in Childhood Acute Lymphoblastic Leukemia

Carl W. Miller, C. Bartram, A. Tobler, 1997 .

Alterations of CDKN2 (p16) in non‐small cell lung cancer

Carl W. Miller, H. Koeffler, A. Gombart, 1995, Genes, chromosomes & cancer.

Absence of WAF1 mutations in a variety of human malignancies.

B. Vogelstein, W. El-Deiry, H. Koeffler, 1994, Blood.

chromosome 12p12.3-13.1 (region of TEL and Kip1 loci) and chromosome 12q23-ter: evidence for two new genes.

J. Yokota, H. Koeffler, S. Takeuchi, 2007 .

Ovarian cancer has frequent loss of heterozygosity at chromosome 12p12.3-13.1 (region of TEL and Kip1 loci) and chromosome 12q23-ter: evidence for two new tumour-suppressor genes.

J. Yokota, H. Koeffler, Y. Hatta, 1997, British Journal of Cancer.

Mutational analysis of the candidate tumor suppressor genes TEL and KIP1 in childhood acute lymphoblastic leukemia.

S. Bohlander, K. Stegmaier, H. Koeffler, 1996, Cancer research.

Mutations of the CHK2 gene are found in some osteosarcomas, but are rare in breast, lung, and ovarian tumors

Carl W. Miller, W. Hofmann, H. Koeffler, 2002, Genes, chromosomes & cancer.

Mutations in the gene encoding the transcription factor CCAAT/enhancer binding protein a in myelodysplastic syndromes and acute myeloid leukemias

Carl W. Miller, W. Hofmann, H. Koeffler, 2002 .

NFV, an HIV-1 protease inhibitor, induces growth arrest, reduced Akt signalling, apoptosis and docetaxel sensitisation in NSCLC cell lines

H. Koeffler, Y. Yang, T. Ikezoe, 2006, British Journal of Cancer.

HIV‐1 protease inhibitor induces growth arrest and apoptosis of human prostate cancer LNCaP cells in vitro and in vivo in conjunction with blockade of androgen receptor STAT3 and AKT signaling

Y. Ohtsuki, Yang Yang, T. Ikezoe, 2005, Cancer science.

Mutations of p53 in Wilms' tumors.

C. Bartram, H. Koeffler, S. Schneider, 1995, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.

Homozygous deletions at 9p21 in childhood acute lymphoblastic leukemia detected by microsatellite analysis

J. Slater, S. Takeuchi, T. Seriu, 1997, Leukemia.

Loss of H19 imprinting in adult T‐cell leukaemia/lymphoma

W. Hofmann, T. Ikezoe, K. Tsukasaki, 2007, British journal of haematology.

Analysis of the CHK2 Gene in Lymphoid Malignancies

Carl W. Miller, W. Hofmann, H. Koeffler, 2001, Leukemia & lymphoma.

DNA aneuploidy in morphologically normal colons from patients with colon cancer.

H. Koeffler, M. Fleischhacker, S. Takeuchi, 1995, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.

Mutation analysis of the DNA-damage checkpoint gene CHK2 in myelodysplastic syndromes and acute myeloid leukemias.

W. Hofmann, H. Koeffler, C. Miller, 2001, Leukemia research.

Establishment of the acute myeloid leukemia cell line Kasumi‐6 from a patient with a dominant‐negative mutation in the DNA‐binding region of the C/EBPα gene

T. Inaba, H. Koeffler, A. Gombart, 2003, Genes, chromosomes & cancer.

Mutational analysis of the Hel-N1 gene in childhood acute lymphoblastic leukemia with LOH at 9p21

H. Koeffler, H. Taguchi, S. Takeuchi, 1999, Leukemia.

p27/Kip1 mutation found in breast cancer.

H. Koeffler, C. Miller, K. Spirin, 1996, Cancer research.

Mutations of the E2F4 gene in hematological malignancies having microsatellite instability.

C. Bartram, H. Koeffler, N. Komatsu, 2000, Blood.

Frameshift mutations in caspase-5 and other target genes in leukemia and lymphoma cell lines having microsatellite instability.

H Phillip Koeffler, H. Koeffler, H. Taguchi, 2003, Leukemia research.

Mutations in the Retinoblastoma-related Gene RB2 / p130 in Adult T-cell Leukaemia/Lymphoma

H. Koeffler, K. Tsukasaki, S. Takeuchi, 2003, Leukemia & lymphoma.

Aberrant methylation in promoter-associated CpG islands of multiple genes in chronic myelogenous leukemia blast crisis.

H. Koeffler, Yang Yang, S. Takeuchi, 2012, Oncology letters.

Absence of microsatellite instability during the progression of chronic myelocytic leukemia

H. Koeffler, H. Mizoguchi, G. Schiller, 1997, Leukemia.

Infrequent microsatellite instability during the evolution of myelodysplastic syndrome to acute myelocytic leukemia.

H. Koeffler, J. Takahara, Y. Hatta, 1996, Leukemia research.

Frequent loss of heterozygosity on the long arm of chromosome 6: identification of two distinct regions of deletion in childhood acute lymphoblastic leukemia.

M. Schrappe, H. Koeffler, A. Reiter, 1998, Cancer research.

Deletion in Childhood Acute Lymphoblastic Leukemia Chromosome 6 : Identification of Two Distinct Regions of Frequent Loss of Heterozygosity on the Long Arm of Updated

M. Schrappe, H. Koeffler, A. Reiter, 2006 .

Microsatellite instability and other molecular abnormalities in childhood acute lymphoblastic leukaemia

C. Bartram, H. Koeffler, J. Slater, 1997, British journal of haematology.

Mutational analysis of the hMSH2 gene in a wide variety of tumors.

Y. Bang, M. Tomonaga, H. Koeffler, 1997, International Journal of Oncology.

P53 codon 72 polymorphism is associated with disease progression in adult T‐cell leukaemia/lymphoma

M. Tomonaga, N. Komatsu, T. Ikezoe, 2005, British journal of haematology.

Methylenetetrahydrofolate reductase genotype does not play a role in adult T-cell leukemia/lymphoma pathogenesis among human T-lymphotrophic virus type 1 carriers.

Carl W. Miller, M. Tomonaga, H. Koeffler, 2004, Leukemia research.

Frequent loss of heterozygosity in the region of D1S450 at 1p36.2 in myelodysplastic syndromes.

D. Xie, W. Hofmann, H. Koeffler, 2001, Leukemia research.

Microsatellite instability during the progression of acute myelocytic leukaemia

H. Koeffler, J. Takahara, S. Takeuchi, 1997, British journal of haematology.

Hybrid eosinophilic-basophilic acute myeloid leukaemia diagnosed by electron microscopy

W. Hofmann, H. Koeffler, T. Ikezoe, 2007 .