I. Cardinale

发表

Multiple Proinflammatory Pathways in TNF Inhibition Rapidly Down-Regulates

J. Krueger, Francesca Chamian, S. Masud, 2005 .

TNF Inhibition Rapidly Down-Regulates Multiple Proinflammatory Pathways in Psoriasis Plaques1

A. Gottlieb, J. Krueger, Francesca Chamian, 2005, The Journal of Immunology.

312-nanometer Ultraviolet B Light (Narrow-Band UVB) Induces Apoptosis of T Cells within Psoriatic Lesions

L. Austin, J. Krueger, I. Cardinale, 1999, The Journal of experimental medicine.

Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis.

G. Yancopoulos, M. Suárez-Fariñas, N. Graham, 2014, The Journal of allergy and clinical immunology.

Atopic dermatitis and skin disease Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis

G. Yancopoulos, N. Graham, G. Pirozzi, 2022 .

Lesional dendritic cells in patients with chronic atopic dermatitis and psoriasis exhibit parallel ability to activate T-cell subsets.

J. Carucci, M. Suárez-Fariñas, J. Krueger, 2011, The Journal of allergy and clinical immunology.

Reversal of atopic dermatitis with narrow-band UVB phototherapy and biomarkers for therapeutic response.

A. Bowcock, S. Duan, M. Suárez-Fariñas, 2011, The Journal of allergy and clinical immunology.

Residual genomic signature of atopic dermatitis despite clinical resolution with narrow-band UVB.

M. Suárez-Fariñas, J. Krueger, I. Cardinale, 2013, The Journal of allergy and clinical immunology.

Cyclosporine in patients with atopic dermatitis modulates activated inflammatory pathways and reverses epidermal pathology.

M. Suárez-Fariñas, M. Rozenblit, J. Krueger, 2014, The Journal of allergy and clinical immunology.

Alefacept (anti-CD2) causes a selective reduction in circulating effector memory T cells (Tem) and relative preservation of central memory T cells (Tcm) in psoriasis

K. Wittkowski, J. Krueger, Francesca Chamian, 2007, Journal of Translational Medicine.

Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris.

K. Wittkowski, J. Krueger, Francesca Chamian, 2005, Proceedings of the National Academy of Sciences of the United States of America.

TNF-alpha Down-Regulates Filaggrin and Loricrin Through c-Jun N-Terminal Kinase: Role for TNF Antagonists to Improve Skin Barrier

M. Boguniewicz, E. Guttman, D. Leung, 2011 .

Effects of etanercept are distinct from infliximab in modulating proinflammatory genes in activated human leukocytes.

J. Krueger, I. Cardinale, A. Haider, 2007, The journal of investigative dermatology. Symposium proceedings.

Cytokines in breast cancer cell dyshesion

J. Krueger, I. Cardinale, I. Tamm, 1998 .

Apilimod Inhibits the Production of IL-12 and IL-23 and Reduces Dendritic Cell Infiltration in Psoriasis

A. Gottlieb, J. Barsoum, J. Chu, 2012, PloS one.

Altered expression of keratinocyte growth factor and its receptor in psoriasis.

P. Finch, J. Krueger, I. Cardinale, 1997, The American journal of pathology.

The human cutaneous squamous cell carcinoma microenvironment is characterized by increased lymphatic density and enhanced expression of macrophage-derived VEGF-C.

J. Carucci, Dariush Moussai, M. Suárez-Fariñas, 2011, The Journal of investigative dermatology.

Molecular profiling of contact dermatitis skin identifies allergen-dependent differences in immune response.

M. Suárez-Fariñas, M. Rozenblit, J. Krueger, 2014, The Journal of allergy and clinical immunology.

PUVA‐induced lymphocyte apoptosis: Mechanism of action in psoriasis

J. Krueger, I. Cardinale, T. Coven, 1999, Photodermatology, photoimmunology & photomedicine.

Novel Insight into the Agonistic Mechanism of Alefacept In Vivo: Differentially Expressed Genes May Serve as Biomarkers of Response in Psoriasis Patients1

James G Krueger, J. Krueger, Francesca Chamian, 2007, The Journal of Immunology.

Low Expression of the IL-23/Th17 Pathway in Atopic Dermatitis Compared to Psoriasis1

J. Carucci, Lisa C. Zaba, R. Bergman, 2008, The Journal of Immunology.

Residual genomic profile after cyclosporine treatment may offer insights into atopic dermatitis reoccurrence.

M. Suárez-Fariñas, M. Rozenblit, J. Krueger, 2014, The Journal of allergy and clinical immunology.

Atopic dermatitis (AD) keratinocytes exhibit normal Th17 cytokine responses

Lisa C. Zaba, R. Bergman, M. Suárez-Fariñas, 2014 .

E-cadherin distribution in interleukin 6-induced cell-cell separation of ductal breast carcinoma cells.

J. Krueger, I. Cardinale, I. Tamm, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Decreased adherence of interleukin 6-treated breast carcinoma cells can lead to separation from neighbors after mitosis.

I. Cardinale, I. Tamm, J. Murphy, 1991, Proceedings of the National Academy of Sciences of the United States of America.

IL32 Is Progressively Expressed in Mycosis Fungoides Independent of Helper T-cell 2 and Helper T-cell 9 Polarization

W. Sterry, M. Suárez-Fariñas, H. Mitsui, 2014, Cancer Immunology Research.

Major differences in inflammatory dendritic cells and their products distinguish atopic dermatitis from psoriasis.

J. Carucci, R. Bergman, J. Krueger, 2007, The Journal of allergy and clinical immunology.

TNF-α downregulates filaggrin and loricrin through c-Jun N-terminal kinase: role for TNF-α antagonists to improve skin barrier.

M. Boguniewicz, D. Leung, J. Krueger, 2011, The Journal of investigative dermatology.

Interleukin 6 decreases cell-cell association and increases motility of ductal breast carcinoma cells

P. Sehgal, J. Krueger, I. Cardinale, 1989, The Journal of experimental medicine.

Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a).

R. Steinman, K. Wittkowski, J. Krueger, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Th17 cytokines interleukin (IL)‐17 and IL‐22 modulate distinct inflammatory and keratinocyte‐response pathways

Lisa C. Zaba, M. Suárez-Fariñas, J. Krueger, 2008, The British journal of dermatology.

IL-22-producing "T22" T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17-producing TH17 T cells.

Lisa C. Zaba, R. Bergman, J. Krueger, 2009, The Journal of allergy and clinical immunology.

Clinical clearing of psoriasis by 6-thioguanine correlates with cutaneous T-cell depletion via apoptosis: evidence for selective effects on activated T lymphocytes.

R. Auerbach, J. Krueger, I. Cardinale, 1999, Archives of dermatology.

Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells.

Lisa C. Zaba, J. Krueger, I. Cardinale, 2008, The Journal of investigative dermatology.

Broad defects in epidermal cornification in atopic dermatitis identified through genomic analysis.

Mayte Suárez-Fariñas, James G Krueger, Andrea Chiricozzi, 2009, The Journal of allergy and clinical immunology.

Intrinsic atopic dermatitis shows similar TH2 and higher TH17 immune activation compared with extrinsic atopic dermatitis.

M. Suárez-Fariñas, J. Krueger, I. Cardinale, 2013, The Journal of allergy and clinical immunology.

Progressive activation of T(H)2/T(H)22 cytokines and selective epidermal proteins characterizes acute and chronic atopic dermatitis.

M. Suárez-Fariñas, H. Mitsui, J. Krueger, 2012, The Journal of allergy and clinical immunology.

Nonlesional atopic dermatitis skin is characterized by broad terminal differentiation defects and variable immune abnormalities.

A. Bowcock, S. Duan, M. Suárez-Fariñas, 2011, The Journal of allergy and clinical immunology.

Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses

Lisa C. Zaba, M. Suárez-Fariñas, J. Krueger, 2007, The Journal of experimental medicine.

Cell-adhesion-disrupting action of interleukin 6 in human ductal breast carcinoma cells.

J G Krueger, J. Krueger, I. Cardinale, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Genomic analysis defines a cancer-specific gene expression signature for human squamous cell carcinoma and distinguishes malignant hyperproliferation from benign hyperplasia.

J. Ott, A. Bowcock, J. Carucci, 2006, The Journal of investigative dermatology.

Integrative responses to IL-17 and TNF-α in human keratinocytes account for key inflammatory pathogenic circuits in psoriasis.

S. Chimenti, S. Tian, M. Suárez-Fariñas, 2011, The Journal of investigative dermatology.

Human basal cell carcinoma is associated with Foxp3+ T cells in a Th2 dominant microenvironment.

J. Carucci, J. Krueger, I. Cardinale, 2007, The Journal of investigative dermatology.

Interleukin-6 and 12-O-tetradecanoyl phorbol-13-acetate act synergistically in inducing cell-cell separation and migration of human breast carcinoma cells.

P. Sehgal, I. Cardinale, I. Tamm, 1991, Cytokine.

Narrowband (312-nm) UV-B suppresses interferon gamma and interleukin (IL) 12 and increases IL-4 transcripts: differential regulation of cytokines at the single-cell level.

J. Krueger, I. Cardinale, P. Gilleaudeau, 2003, Archives of dermatology.

Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes.

Mayte Suárez-Fariñas, James G Krueger, Lisa C. Zaba, 2009, The Journal of allergy and clinical immunology.

PUVA Treatment Selectively Induces a Cell Cycle Block and Subsequent Apoptosis in Human T‐Lymphocytes

L. Staiano‐Coico, L. Austin, J. Krueger, 1996, Photochemistry and Photobiology.

Identification of Cellular Pathways of “Type 1,” Th17 T Cells, and TNF- and Inducible Nitric Oxide Synthase-Producing Dendritic Cells in Autoimmune Inflammation through Pharmacogenomic Study of Cyclosporine A in Psoriasis1

K. Wittkowski, Lisa C. Zaba, M. Suárez-Fariñas, 2008, The Journal of Immunology.

Prominent production of IL-20 by CD68+/CD11c+ myeloid-derived cells in psoriasis: Gene regulation and cellular effects.

J. Krueger, Francesca Chamian, I. Cardinale, 2006, The Journal of investigative dermatology.

Insights into gene modulation by therapeutic TNF and IFNgamma antibodies: TNF regulates IFNgamma production by T cells and TNF-regulated genes linked to psoriasis transcriptome.

J. Ott, Lisa C. Zaba, J. Krueger, 2008, Journal of Investigative Dermatology.

Trimethylpsoralen bath PUVA is a remittive treatment for psoriasis vulgaris. Evidence that epidermal immunocytes are direct therapeutic targets.

J. Krueger, I. Cardinale, P. Gilleaudeau, 1998, Archives of dermatology.

Cellular actions of etretinate in psoriasis: enhanced epidermal differentiation and reduced cell‐mediated inflammation are unexpected outcomes

A. Gottlieb, J. Krueger, I. Cardinale, 1996, Journal of cutaneous pathology.

IL-17 Induces an Expanded Range of Downstream Genes in Reconstituted Human Epidermis Model

M. Suárez-Fariñas, H. Mitsui, J. Krueger, 2014, PloS one.

Cellular genomic maps help dissect pathology in human skin disease.

Lisa C. Zaba, M. Blumenberg, M. Suárez-Fariñas, 2008, The Journal of investigative dermatology.

Intrinsic atopic dermatitis ( AD ) shows similar Th 2 and higher Th 17 immune activation compared to extrinsic AD

M. Suárez-Fariñas, C. G. Strong, I. Cardinale, 2014 .

Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses

Lisa C. Zaba, M. Suárez-Fariñas, J. Krueger, 2008, The Journal of Experimental Medicine.

Molecular profiling of contact dermatitis skin identifies allergen-dependent differences in immune response.

M. Suárez-Fariñas, J. Krueger, I. Cardinale, 2014, The Journal of allergy and clinical immunology.

Atopic dermatitis keratinocytes exhibit normal T(H)17 cytokine responses.

Lisa C. Zaba, R. Bergman, M. Suárez-Fariñas, 2010, The Journal of allergy and clinical immunology.