V. Filichev

发表

Phosphorothioate modification improves exon-skipping of antisense oligonucleotides based on sulfonyl phosphoramidates in mdx mouse myotubes.

R. Veedu, Yongdong Su, P. Raguraman, 2022, Organic & biomolecular chemistry.

Enhanced anti-HIV-1 activity of G-quadruplexes comprising locked nucleic acids and intercalating nucleic acids

E. Pedersen, J. Nielsen, V. Filichev, 2010, Nucleic acids research.

Triplex‐Forming Twisted Intercalating Nucleic Acids (TINAs): Design Rules, Stabilization of Antiparallel DNA Triplexes and Inhibition of G‐Quartet‐Dependent Self‐Association

A. Boutorine, V. Filichev, O. Doluca, 2011, Chembiochem : a European journal of chemical biology.

An alternative synthesis of β-pyrrolic acetylene-substituted porphyrins

K. Jolley, D. Officer, P. Wagner, 2008 .

Cationic modified nucleic acids for use in DNA hairpins and parallel triplexes.

E. Pedersen, V. Filichev, N. Bomholt, 2011, Organic & biomolecular chemistry.

Purine twisted-intercalating nucleic acids: a new class of anti-gene molecules resistant to potassium-induced aggregation

Manikandan Paramasivam, V. Filichev, E. Pedersen, 2008, Nucleic acids research.

High thermal stability of 5'-5'-linked alternate hoogsteen triplexes at physiological pH.

M. C. Nielsen, V. Filichev, E. Pedersen, 2006, Angewandte Chemie.

1-, 2-, and 4-ethynylpyrenes in the structure of twisted intercalating nucleic acids: structure, thermal stability, and fluorescence relationship.

I. V. Astakhova, E. Pedersen, V. Korshun, 2008, Chemistry.

Investigation of twisted intercalating nucleic acid (TINA)-modified antisense oligonucleotides for splice modulation by induced exon-skipping in vitro

R. Veedu, V. Filichev, Bao T. Le, 2016 .

Helicases, G4‐DNAs, and Drug Design

G. Jameson, G. Norris, V. Filichev, 2014, ChemMedChem.

G-Quadruplex Supramolecular Assemblies in Photochemical Upconversion.

P. Derrick, V. Filichev, A. Partridge, 2016, Chemistry.

DNA-Based Assemblies for Photochemical Upconversion.

P. Derrick, V. Filichev, A. Partridge, 2015, The journal of physical chemistry. B.

Stabilization of parallel triplexes by twisted intercalating nucleic acids (TINAs) incorporating 1,2,3-triazole units and prepared by microwave-accelerated click chemistry.

E. Pedersen, V. Filichev, Imrich Géci, 2007, Chemistry.

Twisted Intercalating Nucleic Acids – Intercalator Influence on Parallel Triplex Stabilities

P. T. Jørgensen, V. Filichev, E. Pedersen, 2006 .

Interdependence of pyrene interactions and tetramolecular G4-DNA assembly.

Carlos González, V. Filichev, P. Edwards, 2015, Organic & biomolecular chemistry.

The Importance of Phosphates for DNA G‐Quadruplex Formation: Evaluation of Zwitterionic G‐Rich Oligodeoxynucleotides

D. Stetsenko, Yongdong Su, V. Filichev, 2020, Chembiochem : a European journal of chemical biology.

Small-Angle X-ray Scattering (SAXS) Measurements of APOBEC3G Provide Structural Basis for Binding of Single-Stranded DNA and Processivity

G. Jameson, T. Ryan, Nazanin Mohammadzadeh, 2022, Viruses.

Effects of Pressure and pH on the Physical Stability of an I-Motif DNA Structure.

G. Jameson, V. Filichev, P. Edwards, 2019, Chemphyschem : a European journal of chemical physics and physical chemistry.

α-2'-Deoxyguanosine can switch DNA G-quadruplex topologies from antiparallel to parallel.

G. Norris, V. Filichev, P. Edwards, 2019, Organic & biomolecular chemistry.

DNA duplex as a scaffold for a ground state complex formation between a zinc cationic porphyrin and phenylethynylpyren-1-yl

P. Derrick, V. Filichev, A. Partridge, 2014 .

Optimization of the sequence of twisted intercalating nucleic acids (TINA) forming triple helix with the polypurine tract of the proviral HIV DNA.

A. Boutorine, V. Filichev, O. Doluca, 2009, Nucleic acids symposium series.

The Effect of INA [(R)-1-O-(1-Pyrenylmethyl)Glycerol] Insertions on the Structure and Biological Activity of a G-Quadruplex from a Critical Kras G-Rich Sequence

V. Filichev, E. Pedersen, S. Cogoi, 2007, Nucleosides, nucleotides & nucleic acids.

Stable and selective formation of hoogsteen-type triplexes and duplexes using twisted intercalating nucleic acids (TINA) prepared via postsynthetic Sonogashira solid-phase coupling reactions.

E. Pedersen, V. Filichev, 2005, Journal of the American Chemical Society.

Hexofuranosyl thymidines inserted into oligodeoxynucleotides via their two exocyclic hydroxy groups. Oligo synthesis and RNase H activity.

B. Vester, V. Filichev, E. Pedersen, 2004, Bioorganic & medicinal chemistry.

Synthesis and incorporation of an alpha-hexofuranosyl thymidine into oligodeoxynucleotides via its two exocyclic OH-groups.

V. Filichev, E. Pedersen, 2004, Bioorganic & medicinal chemistry letters.

Design, Synthesis, and Evaluation of a Cross-Linked Oligonucleotide as the First Nanomolar Inhibitor of APOBEC3A

G. Jameson, V. Filichev, M. Kvach, 2022, Biochemistry.

Enhanced Inhibition of Transcription Start by Targeting with 2′‐OMe Pentaribonucleotides Comprising Locked Nucleic Acids and Intercalating Nucleic Acids

L. H. Hansen, J. Wengel, B. Vester, 2005, Chembiochem : a European journal of chemical biology.

Locked Nucleic Acids and Intercalating Nucleic Acids in the Design of Easily Denaturing Nucleic Acids: Thermal Stability Studies

E. Pedersen, J. Wengel, V. Filichev, 2004, Chembiochem : a European journal of chemical biology.

Cover Picture: Assembly Dependent Fluorescence Enhancing Nucleic Acids in Sequence‐Specific Detection of Double‐Stranded DNA (ChemPlusChem 1/2014)

Carlos González, V. Filichev, T. Hale, 2014 .

DNA-Conjugated Organic Chromophores in DNA Stacking Interactions

E. Pedersen, V. Filichev, 2008 .

Triplex Formation by Pyrene‐Labelled Probes for Nucleic Acid Detection in Fluorescence Assays

S. van Calenbergh, V. Filichev, E. Pedersen, 2008, Chembiochem : a European journal of chemical biology.

Intercalating Nucleic Acids: The Influence of Linker Length and Intercalator Type on Their Duplex Stabilities

F. El-Essawy, V. Filichev, E. Pedersen, 2004, Nucleosides, nucleotides & nucleic acids.

Synthesis of β-pyrrolic-modified porphyrins and their incorporation into DNA.

V. Filichev, A. Partridge, Adam W. I. Stephenson, 2011, Chemistry.

Synthesis of 1′-aza-C-nucleosides from (3R,4R)-4-(hydroxymethyl)pyrrolidin-3-ol

E. Pedersen, V. Filichev, 2001 .

Stability of Hoogsteen-type triplexes - electrostatic attraction between duplex backbone and triplex-forming oligonucleotide (TFO) using an intercalating conjugate

V. Filichev, D. Globisch, E. Pedersen, 2008 .

Intercalating nucleic acids (INAs) with insertion of N-(pyren-1-ylmethyl)-(3R,4R)-4-(hydroxymethyl)pyrrolidin-3-ol. DNA (RNA) duplex and DNA three-way junction stabilities.

E. Pedersen, V. Filichev, 2003, Organic & biomolecular chemistry.

Synthesis of 1′‐Aza‐C‐nucleosides from (3R,4R)‐4‐(Hydroxymethyl)pyrrolidin‐3‐ol.

E. Pedersen, V. Filichev, 2002 .

Molecular engineering of guanine-rich sequences: Z-DNA, DNA triplexes, and G-quadruplexes.

V. Filichev, Jamie M. Withers, O. Doluca, 2013, Chemical Reviews.

Significantly Enhanced DNA Thermal Stability Resulting from Porphyrin H‐Aggregate Formation in the Minor Groove of the Duplex

V. Filichev, A. Partridge, N. Bomholt, 2010, Chembiochem : a European journal of chemical biology.

Differential Inhibition of APOBEC3 DNA‐Mutator Isozymes by Fluoro‐ and Non‐Fluoro‐Substituted 2′‐Deoxyzebularine Embedded in Single‐Stranded DNA

R. D’Aquila, L. Sutton, G. Jameson, 2019, Chembiochem : a European journal of chemical biology.

Synthesis of novel thymidine derivatives containing a polycyclic tetrazole linker

V. Filichev, V. Ostrovskii, M. Jasko, 2002 .

Selective inhibition of APOBEC3 enzymes by single-stranded DNAs containing 2'-deoxyzebularine.

G. Jameson, V. Filichev, M. Kvach, 2019, Organic & biomolecular chemistry.

Inhibiting APOBEC3 Activity with Single-Stranded DNA Containing 2′-Deoxyzebularine Analogues

G. Jameson, D. Harki, H. Aihara, 2018, Biochemistry.

The First Postsynthetic 5'-5' Intercalators in Triplex DNA -Solid-Phase Postsynthetic Sonogashira Reaction and Homocouplings on Arylacetylenes

E. Pedersen, V. Filichev, N. Bomholt, 2009 .

Synthesis of twisted intercalating nucleic acids possessing acridine derivatives. Thermal stability studies.

E. Pedersen, V. Filichev, Imrich Géci, 2006, Bioconjugate chemistry.

Easily denaturing nucleic acids derived from intercalating nucleic acids: thermal stability studies, dual duplex invasion and inhibition of transcription start

L. H. Hansen, E. Pedersen, B. Vester, 2005, Nucleic acids research.

Towards Metal-Mediated G-Quartet Analogues: 1,2,4-Triazole Nucleotides

S. Telfer, V. Filichev, Jamie M. Withers, 2015, Nucleosides, nucleotides & nucleic acids.

Application of Cu(I)-catalyzed azide–alkyne cycloaddition for the design and synthesis of sequence specific probes targeting double-stranded DNA

A. Boutorine, V. Filichev, S. Vasilyeva, 2016, Beilstein journal of organic chemistry.

Assembly Dependent Fluorescence Enhancing Nucleic Acids in Sequence-Specific Detection of Double-Stranded DNA.

V. Filichev, T. Hale, P. Edwards, 2014, ChemPlusChem.

DNA with zwitterionic and negatively charged phosphate modifications: formation of DNA triplexes, duplexes and cell permeability studies

Yongdong Su, V. Filichev, T. Hale, 2020 .

NMR-based method of small changes reveals how DNA mutator APOBEC3A interacts with its single-stranded DNA substrate

G. Jameson, V. Filichev, P. Edwards, 2017, Nucleic acids research.

Intercalating nucleic acids: The inversion of the stereocenter in 1-O-(pyren-1-ylmethyl)glycerol from R to S. Thermal stability towards ssDNA, ssRNA and its own type of oligodeoxynucleotides☆

E. Pedersen, V. Filichev, K. Hilmy, 2004 .

Heterochromatin protein 1α interacts with parallel RNA and DNA G-quadruplexes

Carlos González, Miguel Garavís, G. Jameson, 2019, Nucleic acids research.

DNA G‐quadruplexes show strong interaction with DNA methyltransferases in vitro

M. Kennedy, A. Miller, C. Fee, 2016, FEBS letters.

Uncoupling Molecular Testing for SARS-CoV-2 From International Supply Chains

R. Blaikie, M. Quiñones-Mateu, Patrick D. Collins, 2022, Frontiers in Public Health.

G-Quadruplex Structures and CpG Methylation Cause Drop-Out of the Maternal Allele in Polymerase Chain Reaction Amplification of the Imprinted MEST Gene Promoter

Michael R. Eccles, Kit Doudney, M. Eccles, 2014, PloS one.

Ligand assembly and chirality transfer guided by DNA modified with enantiomerically pure [2.2]paracyclophanes

V. Filichev, G. Rowlands, Jamie M. Withers, 2013 .

Neutral and Negatively Charged Phosphate Modifications Altering Thermal Stability, Kinetics of Formation and Monovalent Ion Dependence of DNA G-Quadruplexes.

B. Chelobanov, M. Fujii, D. Stetsenko, 2019, Chemistry, an Asian journal.

Small-Angle X-ray Scattering Models of APOBEC3B Catalytic Domain in a Complex with a Single-Stranded DNA Inhibitor

G. Jameson, T. Ryan, H. Aihara, 2021, Viruses.

Identification of a new G-quadruplex motif in the KRAS promoter and design of pyrene-modified G4-decoys with antiproliferative activity in pancreatic cancer cells.

Imrich Géci, Manikandan Paramasivam, V. Filichev, 2009, Journal of medicinal chemistry.

NUCLEOSIDES, NUCLEOTIDES & NUCLEIC ACIDS

F. El-Essawy, V. Filichev, E. Pedersen, 2004 .

Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A

G. Jameson, Yongdong Su, V. Filichev, 2023, bioRxiv.

Molecular engineering of guanine-rich sequences: Z-DNA, DNA triplexes, and G-quadruplexes.

V. Filichev, Jamie M. Withers, O. Doluca, 2013, Chemical reviews.

DNA visualization in single molecule studies carried out with optical tweezers: Covalent versus non-covalent attachment of fluorophores.

V. Filichev, S. Keen, A. Raudsepp, 2015, Biochemical and Biophysical Research Communications - BBRC.

Understanding intercalative modulation of G-rich sequence folding: solution structure of a TINA-conjugated antiparallel DNA triplex

V. Filichev, M. Garavís, O. Doluca, 2024, Nucleic acids research.