Yan Zhang

发表

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

Kristen S Purrington, Jack A. Taylor, A. Whittemore, 2018, American Journal of Human Genetics.

Epigenetic age acceleration predicts cancer, cardiovascular, and all-cause mortality in a German case cohort

H. Brenner, K. Saum, U. Mons, 2016, Clinical Epigenetics.

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

Jane E. Carpenter, Jaana M. Hartikainen, W. Chung, 2019, Nature Genetics.

DNA methylation changes of whole blood cells in response to active smoking exposure in adults: a systematic review of DNA methylation studies

H. Brenner, Yan Zhang, Xu Gao, 2015, Clinical Epigenetics.

Identification of prognostic DNA methylation biomarkers in patients with gastrointestinal adenocarcinomas: A systematic review of epigenome-wide studies.

H. Brenner, M. Hoffmeister, E. Alwers, 2019, Cancer treatment reviews.

Smoking-associated DNA methylation markers predict lung cancer incidence

Bernd Holleczek, Hermann Brenner, Alexandra Nieters, 2016, Clinical Epigenetics.

Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes

Jack A. Taylor, W. Chung, S. Cross, 2019, bioRxiv.

Epigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption

P. Elliott, P. Tsai, M. Fornage, 2020, Nature Communications.

Integrative analysis of clinical and epigenetic biomarkers of mortality

E. Colicino, J. Bressler, M. Fornage, 2022, Aging cell.

DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases

Pashupati P. Mishra, P. Elliott, M. Jarvelin, 2021, Nature communications.

Individual and joint performance of DNA methylation profiles, genetic risk score and environmental risk scores for predicting breast cancer risk

H. Brenner, B. Schöttker, K. Weigl, 2019, Molecular oncology.

Different definitions of CpG island methylator phenotype and outcomes of colorectal cancer: a systematic review

H. Brenner, M. Hoffmeister, Yan Zhang, 2016, Clinical Epigenetics.

Circulating MicroRNA Biomarkers for Lung Cancer Detection in East Asian Populations

H. Brenner, K. Ćuk, Yan Zhang, 2019, Cancers.

Genome-wide association study of germline variants and breast cancer-specific mortality

A. Whittemore, W. Willett, S. Cross, 2019, British Journal of Cancer.

The associations of DNA methylation alterations in oxidative stress-related genes with cancer incidence and mortality outcomes: a population-based cohort study

H. Brenner, B. Schöttker, B. Burwinkel, 2019, Clinical Epigenetics.

Association of prenatal organochlorine pesticide‐dichlorodiphenyltrichloroethane exposure with fetal genome‐wide DNA methylation

Ze-yu Zhao, Yan Zhang, Q. Cheng, 2018, Life sciences.

Gastric Parietal Cell Antibodies, Helicobacter Pylori Infection, and Chronic Atrophic Gastritis: Evidence from a Large Population-based Study in Germany

H. Brenner, D. Rothenbacher, B. Schöttker, 2013, Cancer Epidemiology, Biomarkers & Prevention.

Association of helicobacter pylori infection and chronic atrophic gastritis with risk of colonic, pancreatic and gastric cancer: A ten-year follow-up of the ESTHER cohort study

H. Brenner, B. Schöttker, B. Holleczek, 2016, Oncotarget.

Comparative validation of three DNA methylation algorithms of ageing and a frailty index in relation to mortality: results from the ESTHER cohort study

H. Brenner, B. Schöttker, Xiangwei Li, 2021, EBioMedicine.

DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases

Pashupati P. Mishra, P. Elliott, M. Jarvelin, 2021, Nature Communications.

Genome-wide association study of germline variants and breast cancer-speci ﬁ c mortality

A. Whittemore, M. Beckmann, A. Talhouk, 2019 .

Genome-wide association study of germline variants and breast cancer-specific mortality

A. Whittemore, W. Willett, S. Cross, 2019, British Journal of Cancer.

The Potential Role of m6A RNA Methylation in the Aging Process and Aging-Associated Diseases

Ping Zhu, Yan Zhang, Shuxia Wang, 2022, Frontiers in Genetics.

IDENTIFICATION OF FACTORS INVOLVED IN DNA METHYLATION OF CPG-ISLAND-PROMOTERS

Yan Zhang, 2011 .

F2RL3 Methylation as a Biomarker of Current and Lifetime Smoking Exposures

Barbara Burwinkel, Rongxi Yang, Hermann Brenner, 2013, Environmental health perspectives.

Epigenetic Link Between Statin Therapy and Type 2 Diabetes

Pashupati P. Mishra, C. Gieger, M. Waldenberger, 2020, Diabetes Care.

Whole Blood DNA Methylation Signatures of Diet Are Associated With Cardiovascular Disease Risk Factors and All-Cause Mortality

E. Colicino, E. Demerath, M. Fornage, 2020, Circulation. Genomic and precision medicine.

Blood‐derived DNA methylation predictors of mortality discriminate tumor and healthy tissue in multiple organs

H. Brenner, M. Hoffmeister, B. Burwinkel, 2020, Molecular oncology.

DNA methylation changes of whole blood cells in response to active smoking exposure in adults: a systematic review of DNA methylation studies

H. Brenner, Yan Zhang, Xu Gao, 2015, Clinical Epigenetics.

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

Jane E. Carpenter, Jack A. Taylor, W. Chung, 2019, Nature Genetics.

F2RL3 methylation, lung cancer incidence and mortality

H. Brenner, B. Schöttker, B. Burwinkel, 2015, International journal of cancer.

Type 2 diabetes and leucocyte DNA methylation: an epigenome-wide association study in over 1,500 older adults

Jonathan A. Heiss, H. Brenner, B. Schöttker, 2015, Diabetologia.

A prognostic CpG score derived from epigenome-wide profiling of tumor tissue was independently associated with colorectal cancer survival

M. Kloor, H. Brenner, J. Chang-Claude, 2019, Clinical Epigenetics.

Childhood exposure to hunger: associations with health outcomes in later life and epigenetic markers.

H. Brenner, M. Kliegel, B. Schöttker, 2020, Epigenomics.

Discovery of a novel epigenetic cancer marker related to the oxidative status of human blood

Jonathan A. Heiss, H. Brenner, B. Schöttker, 2015, Genes, chromosomes & cancer.

Individual CpG sites that are associated with age and life expectancy become hypomethylated upon aging

Wolfgang Wagner, Hermann Brenner, Yan Zhang, 2017, Clinical Epigenetics.

Individual and joint contributions of genetic and methylation risk scores for enhancing lung cancer risk stratification: data from a population-based cohort in Germany

B. Schöttker, B. Holleczek, Yan Zhang, 2020, Clinical Epigenetics.

Methylomic survival predictors, frailty, and mortality

H. Brenner, B. Schöttker, K. Saum, 2018, Aging.

Whole genome methylation combined with RNA-seq reveals the protective effects of Gualou-Xiebai herb pair in foam cells through DNA methylation mediated PI3K-AKT signaling pathway

Yan Zhang, Jun Mei, Qingbing Zhou, 2023, Frontiers in Immunology.

Relationship of tobacco smoking and smoking-related DNA methylation with epigenetic age acceleration

H. Brenner, Yan Zhang, Xu Gao, 2016, OncoTarget.

Associations of Helicobacter pylori infection and chronic atrophic gastritis with accelerated epigenetic ageing in older adults

H. Brenner, Yan Zhang, Xu Gao, 2017, British Journal of Cancer.

Smoking-associated DNA methylation markers predict lung cancer incidence

H. Brenner, B. Schöttker, B. Holleczek, 2016, Clinical Epigenetics.

Epigenome-wide association study of incident type 2 diabetes: a meta-analysis of five prospective European cohorts

C. Gieger, W. Rathmann, H. Snieder, 2022, Diabetologia.

Whole-Blood DNA Methylation Markers in Early Detection of Breast Cancer: A Systematic Literature Review

H. Brenner, K. Ćuk, Yan Zhang, 2018, Cancer Epidemiology, Biomarkers & Prevention.

Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline.

Karsten B. Sieber, Pashupati P. Mishra, Audrey Y. Chu, 2020, Kidney international.

Oxidative stress and epigenetic mortality risk score: associations with all-cause mortality among elderly people

B. Schöttker, B. Holleczek, Yan Zhang, 2019, European Journal of Epidemiology.

Vitamin D status and epigenetic-based mortality risk score: strong independent and joint prediction of all-cause mortality in a population-based cohort study

H. Brenner, B. Schöttker, Yan Zhang, 2018, Clinical Epigenetics.

DNA methylation signatures in peripheral blood strongly predict all-cause mortality

Jonathan A. Heiss, M. Waldenberger, A. Peters, 2017, Nature Communications.

Epigenetic age acceleration predicts cancer, cardiovascular, and all-cause mortality in a German case cohort

H. Brenner, K. Saum, U. Mons, 2016, Clinical Epigenetics.

DNAm-based signatures of accelerated aging and mortality in blood are associated with low renal function

S. Horvath, E. Colicino, C. Ward‐Caviness, 2021, Clinical Epigenetics.

Leukocyte telomere length and epigenetic-based mortality risk score: associations with all-cause mortality among older adults

H. Brenner, U. Mons, Yan Zhang, 2018, Epigenetics.

Tobacco smoking and smoking-related DNA methylation are associated with the development of frailty among older adults

H. Brenner, B. Schöttker, K. Saum, 2017, Epigenetics.

DNA methylation changes in response to active smoking exposure are associated with leukocyte telomere length among older adults

H. Brenner, U. Mons, Yan Zhang, 2016, European Journal of Epidemiology.

Whole blood DNA methylation aging markers predict colorectal cancer survival: a prospective cohort study

H. Brenner, J. Chang-Claude, M. Hoffmeister, 2020, Clinical epigenetics.

Serum 25-Hydroxyvitamin D Levels as an Aging Marker: Strong Associations With Age and All-Cause Mortality Independent From Telomere Length, Epigenetic Age Acceleration, and 8-Isoprostane Levels

B. Schöttker, B. Holleczek, Yan Zhang, 2018, The journals of gerontology. Series A, Biological sciences and medical sciences.

Tobacco smoking and methylation of genes related to lung cancer development

H. Brenner, Yan Zhang, Xu Gao, 2016, Oncotarget.

F2RL3 methylation in blood DNA is a strong predictor of mortality.

H. Brenner, B. Schöttker, B. Burwinkel, 2014, International journal of epidemiology.

American Journal of Epidemiology Original Contribution Helicobacter Pylori Infection and Colorectal Cancer Risk: Evidence from a Large Population-based Case-control Study in Germany

Hermann Brenner, Jenny Chang-Claude, Michael Hoffmeister, 2022 .

Socioeconomic position, lifestyle habits and biomarkers of epigenetic aging: a multi-cohort analysis

E. Colicino, A. Just, P. Vokonas, 2019, Aging.

Self-reported smoking, serum cotinine, and blood DNA methylation.

H. Brenner, K. Saum, I. Florath, 2016, Environmental research.

Associated Links Among Smoking, Chronic Obstructive Pulmonary Disease, and Small Cell Lung Cancer: A Pooled Analysis in the International Lung Cancer Consortium.

H. Morgenstern, L. Kiemeney, Hongbing Shen, 2015, EBioMedicine.

DNA Methylation-Based Estimates of Circulating Leukocyte Composition for Predicting Colorectal Cancer Survival: A Prospective Cohort Study

H. Brenner, J. Chang-Claude, M. Hoffmeister, 2021, Cancers.

Comparison and combination of blood DNA methylation at smoking‐associated genes and at lung cancer‐related genes in prediction of lung cancer mortality

H. Brenner, B. Schöttker, B. Holleczek, 2016, International journal of cancer.

The impact of methylation quantitative trait loci (mQTLs) on active smoking-related DNA methylation changes

H. Brenner, H. Thomsen, Yan Zhang, 2017, Clinical Epigenetics.

Associated Links Among Smoking, Chronic Obstructive Pulmonary Disease, and Small Cell Lung Cancer: A Pooled Analysis in the International Lung Cancer Consortium

H. Morgenstern, L. Kiemeney, Hongbing Shen, 2015, EBioMedicine.

Circulating microRNA biomarkers for lung cancer detection in Western populations

H. Brenner, K. Ćuk, Yan Zhang, 2018, Cancer medicine.

Urinary 8‐isoprostane levels and occurrence of lung, colorectal, prostate, breast and overall cancer: Results from a large, population‐based cohort study with 14 years of follow‐up

H. Brenner, B. Schöttker, K. Ćuk, 2018, Free radical biology & medicine.

Investigation on potential associations of oxidatively generated DNA/RNA damage with lung, colorectal, breast, prostate and total cancer incidence

H. Brenner, B. Schöttker, K. Ćuk, 2019, Scientific Reports.

Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults

Pashupati P. Mishra, C. Gieger, Sonja Kunze, 2018, EBioMedicine.

Subjective mental health, incidence of depressive symptoms in later life, and the role of epigenetics: results from two longitudinal cohort studies

M. Waldenberger, A. Peters, H. Brenner, 2020, Translational Psychiatry.

A serum microRNA signature for enhanced selection of people for lung cancer screening

P. Schrotz-King, B. Schöttker, B. Holleczek, 2022, Cancer Communications.

Pre‐diagnostic derivatives of reactive oxygen metabolites and the occurrence of lung, colorectal, breast and prostate cancer: An individual participant data meta‐analysis of two large population‐based studies

H. Brenner, B. Schöttker, T. Wilsgaard, 2019, International journal of cancer.

Associations of self-reported smoking, cotinine levels and epigenetic smoking indicators with oxidative stress among older adults: a population-based study

H. Brenner, B. Schöttker, Yan Zhang, 2017, European Journal of Epidemiology.

Smoking-Associated DNA Methylation Biomarkers and Their Predictive Value for All-Cause and Cardiovascular Mortality

H. Brenner, B. Schöttker, U. Mons, 2015, Environmental health perspectives.

Individual CpG sites that are associated with age and life expectancy become hypomethylated upon aging

H. Brenner, W. Wagner, Yan Zhang, 2017, Clinical Epigenetics.

Individual and joint contributions of genetic and methylation risk scores for enhancing lung cancer risk stratification: data from a population-based cohort in Germany

H. Brenner, B. Schöttker, B. Holleczek, 2020, Clinical Epigenetics.

The associations of DNA methylation alterations in oxidative stress-related genes with cancer incidence and mortality outcomes: a population-based cohort study

H. Brenner, B. Schöttker, B. Burwinkel, 2019, Clinical Epigenetics.

Different definitions of CpG island methylator phenotype and outcomes of colorectal cancer: a systematic review

H. Brenner, M. Hoffmeister, Yan Zhang, 2016, Clinical Epigenetics.

The impact of methylation quantitative trait loci (mQTLs) on active smoking-related DNA methylation changes

H. Brenner, H. Thomsen, Yan Zhang, 2017, Clinical Epigenetics.

Investigation on potential associations of oxidatively generated DNA/RNA damage with lung, colorectal, breast, prostate and total cancer incidence

H. Brenner, B. Schöttker, B. Holleczek, 2019, Scientific Reports.

Relationship of tobacco smoking and smoking-related DNA methylation with epigenetic age acceleration

H. Brenner, Yan Zhang, Xu Gao, 2016, Oncotarget.

Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults

Pashupati P. Mishra, C. Gieger, Sonja Kunze, 2018, EBioMedicine.

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

Kristen S Purrington, Jack A. Taylor, A. Whittemore, 2018, American Journal of Human Genetics.

Genome-wide association study of germline variants and breast cancer-specific mortality

A. Whittemore, W. Willett, S. Cross, 2019, British Journal of Cancer.

The role of epigenetic clocks in explaining educational inequalities in mortality: a multi-cohort study and meta-analysis.

M. Levine, M. Waldenberger, J. V. van Meurs, 2022, The journals of gerontology. Series A, Biological sciences and medical sciences.