D. Summerer

发表

Selective recognition of N4-methylcytosine in DNA by engineered transcription-activator-like effectors

Preeti Rathi, Sara Maurer, D. Summerer, 2018, Philosophical Transactions of the Royal Society B: Biological Sciences.

Control of protein phosphorylation with a genetically encoded photocaged amino acid.

Peter G Schultz, Edward A Lemke, P. Schultz, 2007, Nature chemical biology.

Genetically Encoded Spin Labels for In Vitro and In-Cell EPR Studies of Native Proteins.

M. Drescher, D. Summerer, M. J. Schmidt, 2015, Methods in enzymology.

Red-light-controlled protein-RNA crosslinking with a genetically encoded furan.

D. Summerer, M. Schmidt, 2013, Angewandte Chemie.

Light‐Activation of DNA‐Methyltransferases

M. Schweiger, Benjamin C. Buchmuller, P. Janning, 2021, Angewandte Chemie.

Light‐Activation of DNA‐Methyltransferases

M. Schweiger, Benjamin C. Buchmuller, P. Janning, 2021 .

Evolved DNA Duplex Readers for Strand-Asymmetrically Modified 5-Hydroxymethylcytosine/5-Methylcytosine CpG Dyads

M. Drescher, Benjamin C. Buchmuller, D. Summerer, 2022, Journal of the American Chemical Society.

Hibernation and torpor, prospects for human spaceflight?

V. Vyazovskiy, R. Henning, M. Cerri, 2018 .

Recognition of Oxidized 5-Methylcytosine Derivatives in DNA by Natural and Engineered Protein Scaffolds.

D. Summerer, Á. Muñoz‐López, Álvaro Muñoz‐López, 2018, Chemical record.

Site-specific PEGylation of proteins containing unnatural amino acids.

P. Schultz, M. Mukherji, A. Deiters, 2004, Bioorganic & medicinal chemistry letters.

Light-Activatable TET-Dioxygenases Reveal Dynamics of 5-Methylcytosine Oxidation and Transcriptome Reorganization.

Paul Czodrowski, Benjamin C. Buchmuller, D. Summerer, 2020, Journal of the American Chemical Society.

A genetically encoded spin label for electron paramagnetic resonance distance measurements.

M. Drescher, D. Summerer, M. Schmidt, 2014, Journal of the American Chemical Society.

A Genetically Encoded Diazirine Photocrosslinker in Escherichia coli

P. Schultz, W. Liu, D. Summerer, 2007, Chembiochem : a European journal of chemical biology.

The genetic incorporation of a distance probe into proteins in Escherichia coli.

P. Schultz, D. Summerer, Meng-Lin Tsao, 2006, Journal of the American Chemical Society.

Combining site-directed spin labeling in vivo and in-cell EPR distance determination.

M. Drescher, D. Summerer, Pia Widder, 2019, Physical chemistry chemical physics : PCCP.

A flexible and fully integrated system for amplification, detection and genotyping of genomic DNA targets based on microfluidic oligonucleotide arrays.

M. Beier, C. Stähler, D. Summerer, 2010, New biotechnology.

Engineered TALE Repeats for Enhanced Imaging‐Based Analysis of Cellular 5‐Methylcytosine

Benjamin C. Buchmuller, Sara Maurer, D. Summerer, 2020, Chembiochem : a European journal of chemical biology.

Complete Profiling of Methyl-CpG-Binding Domains for Combinations of Cytosine Modifications at CpG Dinucleotides Reveals Differential Read-out in Normal and Rett-Associated States

Benjamin C. Buchmuller, D. Summerer, Brinja Kosel, 2020, Scientific Reports.

Programmable Protein-DNA Cross-Linking for the Direct Capture and Quantification of 5-Formylcytosine.

Benjamin C. Buchmuller, D. Summerer, Grzegorz Kubik, 2019, Journal of the American Chemical Society.

Epigenetic CpG duplex marks probed by an evolved DNA reader via a well-tempered conformational plasticity

Lars V. Schäfer, C. K. Das, Benjamin C. Buchmuller, 2022, bioRxiv.

DNA-templated synthesis: more versatile than expected.

A. Marx, D. Summerer, 2002, Angewandte Chemie.

Site-directed spin labelling of proteins by Suzuki-Miyaura coupling via a genetically encoded aryliodide amino acid.

M. Drescher, D. Summerer, Theresa S Braun, 2019, Chemical communications.

Expanding the Genetic Code for Site-Directed Spin-Labeling

M. Drescher, D. Summerer, Theresa S Braun, 2019, International journal of molecular sciences.

Varied DNA Polymerase—Substrate Interactions in the Nucleotide Binding Pocket

A. Marx, D. Summerer, M. Strerath, 2002, Chembiochem : a European journal of chemical biology.

Differential minor groove interactions between DNA polymerase and sugar backbone of primer and template strands.

A. Marx, D. Summerer, 2002, Journal of the American Chemical Society.

A genetically encoded fluorescent amino acid.

Peter G Schultz, Alexander Deiters, P. Schultz, 2006, Proceedings of the National Academy of Sciences of the United States of America.

DNA minor groove hydration probed with 4'-alkylated thymidines.

A. Marx, D. Summerer, I. Detmer, 2002, Chemical communications.

Molecular Insights into Error‐Prone DNA Replication and Error‐Free Lesion Bypass

A. Marx, D. Summerer, 2002, Chembiochem : a European journal of chemical biology.

4'C-ethynyl-thymidine acts as a chain terminator during DNA-synthesis catalyzed by HIV-1 reverse transcriptase.

D. Summerer, A. Marx, 2005, Bioorganic & medicinal chemistry letters.

4'C-modified nucleotides as chemical tools for investigation and modulation of DNA polymerase function

A. Marx, D. Summerer, 2004 .

A molecular beacon for quantitative monitoring of the DNA polymerase reaction in real-time.

A. Marx, D. Summerer, 2002, Angewandte Chemie.

Increased Single‐Nucleotide Discrimination of PCR by Primer Probes Bearing Hydrophobic 4′C Modifications

A. Marx, D. Summerer, M. Strerath, 2004, Chembiochem : a European journal of chemical biology.

Structural Basis of Furan–Amino Acid Recognition by a Polyspecific Aminoacyl‐tRNA‐Synthetase and its Genetic Encoding in Human Cells

W. Welte, A. Weber, D. Summerer, 2014, Chembiochem : a European journal of chemical biology.

Genetic code expansion as a tool to study regulatory processes of transcription

D. Summerer, Moritz J. Schmidt, Daniel Summerer, 2014, Front. Chem..

Enabling technologies of genomic-scale sequence enrichment for targeted high-throughput sequencing.

D. Summerer, 2009, Genomics.

Genetically encoded fluorophenylalanines enable insights into the recognition of lysine trimethylation by an epigenetic reader.

Jeffery M. Tharp, W. Liu, A. Weber, 2016, Chemical communications.

Double Nitroxide Labeling by Copper-Catalyzed Azide–Alkyne Cycloadditions with Noncanonical Amino Acids for Electron Paramagnetic Resonance Spectroscopy

M. Drescher, D. Summerer, Pia Widder, 2019, ACS chemical biology.

Site-directed spin labeling of proteins for distance measurements in vitro and in cells.

M. Drescher, D. Summerer, M. J. Schmidt, 2016, Organic & biomolecular chemistry.

DNA polymerase profiling.

D. Summerer, 2008, Methods in molecular biology.

Targeted high throughput sequencing of a cancer-related exome subset by specific sequence capture with a fully automated microarray platform.

Haiguo Wu, Markus Beier, M. Beier, 2010, Genomics.

Microarray-based multicycle-enrichment of genomic subsets for targeted next-generation sequencing.

M. Chee, M. Beier, B. Haase, 2009, Genome research.

Targeted next-generation sequencing by specific capture of multiple genomic loci using low-volume microfluidic DNA arrays

M. Beier, D. Summerer, M. Kränzle, 2009, Analytical and bioanalytical chemistry.

Programmable and highly resolved in vitro detection of 5-methylcytosine by TALEs.

D. Summerer, Grzegorz Kubik, M. Schmidt, 2014, Angewandte Chemie.

Specific sequence selection and next generation resequencing of 68 E. coli genes using HybSelect.

M. Beier, D. Summerer, P. Stähler, 2009, New Biotechnology.

Achieving Single‐Nucleotide Resolution of 5‐Methylcytosine Detection with TALEs

D. Summerer, Grzegorz Kubik, 2015, Chembiochem : a European journal of chemical biology.

Encoded, click-reactive DNA-binding domains for programmable capture of specific chromatin segments†

M. Schweiger, P. Janning, D. Summerer, 2020, Chemical science.

High‐Throughput DNA Sequencing Beyond the Four‐Letter Code: Epigenetic Modifications Revealed by Single‐Molecule Bypass Kinetics

D. Summerer, 2010, Chembiochem : a European journal of chemical biology.

Application of the C4'-Alkylated Deoxyribose Primer System (CAPS) in Allele-Specific Real-Time PCR for Increased Selectivity in Discrimination of Single Nucleotide Sequence Variants

A. Pingoud, P. Friedhoff, A. Marx, 2003, Biological chemistry.

Design and Application of DNA Modification-Specific Transcription-Activator-Like Effectors.

Benjamin C. Buchmuller, D. Summerer, Á. Muñoz‐López, 2021, Methods in molecular biology.

Complete Profiling of Methyl-CpG-Binding Domains for Combinations of Cytosine Modifications at CpG Dinucleotides Reveals Differential Read-out in Normal and Rett-Associated States

Benjamin C. Buchmuller, D. Summerer, B. Kosel, 2020, Scientific Reports.

Overcoming conservation in TALE–DNA interactions: a minimal repeat scaffold enables selective recognition of an oxidized 5-methylcytosine† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc01958d

C. Ehrt, O. Koch, Benjamin C. Buchmuller, 2018, Chemical science.

Interrogating Key Positions of Size-Reduced TALE Repeats Reveals a Programmable Sensor of 5-Carboxylcytosine.

O. Koch, Sara Maurer, D. Summerer, 2016, ACS chemical biology.

Isolation of Human Genomic DNA Sequences with Expanded Nucleobase Selectivity.

Preeti Rathi, Sara Maurer, D. Summerer, 2016, Journal of the American Chemical Society.

TALEored Epigenetics: A DNA‐Binding Scaffold for Programmable Epigenome Editing and Analysis

D. Summerer, Grzegorz Kubik, 2016, Chembiochem : a European journal of chemical biology.

HybSelect: high-throughput access to genomic regions of interest for targeted next-generation sequencing

D. Summerer, 2009 .

Programmable tools for targeted analysis of epigenetic DNA modifications.

Benjamin C. Buchmuller, D. Summerer, Á. Muñoz‐López, 2021, Current opinion in chemical biology.

Deciphering Epigenetic Cytosine Modifications by Direct Molecular Recognition.

D. Summerer, Grzegorz Kubik, 2015, ACS chemical biology.

Programmable sensors of 5-hydroxymethylcytosine.

D. Summerer, Grzegorz Kubik, Sabrina Batke, 2015, Journal of the American Chemical Society.

Designer Receptors for Nucleotide‐Resolution Analysis of Genomic 5‐Methylcytosine by Cellular Imaging

M. Schweiger, Benjamin C. Buchmuller, M. Hussong, 2020, Angewandte Chemie.

Engineering DNA Backbone Interactions Results in TALE Scaffolds with Enhanced 5-Methylcytosine Selectivity

Preeti Rathi, D. Summerer, A. Witte, 2017, Scientific Reports.

EPR Distance Measurements in Native Proteins with Genetically Encoded Spin Labels.

C. Peter, M. Drescher, D. Summerer, 2015, ACS chemical biology.

Optochemical Control of TET Dioxygenases Enables Kinetic Insights into the Domain-Dependent Interplay of TET1 and MBD1 while Oxidizing and Reading 5-Methylcytosine

D. Summerer, Tzu-Chen Lin, Shubhendu Palei, 2022, ACS chemical biology.

Pericentromeric Satellite III transcripts induce etoposide resistance

M. Odenthal, R. Büttner, C. Grimm, 2021, Cell Death & Disease.

Site-specific labeling of proteins with NMR-active unnatural amino acids

Susan E. Cellitti, P. Schultz, B. Geierstanger, 2010, Journal of biomolecular NMR.

Engineering of ribozyme-based aminoglycoside switches of gene expression by in vivo genetic selection in Saccharomyces cerevisiae.

Benedikt Klauser, D. Summerer, Charlotte Rehm, 2015, Methods in enzymology.

The N6-Position of Adenine Is a Blind Spot for TAL-Effectors That Enables Effective Binding of Methylated and Fluorophore-Labeled DNA.

O. Koch, E. Weinhold, Matyas Juhasz, 2017, ACS chemical biology.

N(6) -Methyladenine: A Potential Epigenetic Mark in Eukaryotic Genomes.

D. Summerer, 2015, Angewandte Chemie.

Isoindoline‐Based Nitroxides as Bioresistant Spin Labels for Protein Labeling through Cysteines and Alkyne‐Bearing Noncanonical Amino Acids

M. Drescher, D. Summerer, Moritz Schmidt, 2019, Chembiochem : a European journal of chemical biology.

DNA. A Graphic Guide to the Molecule that Shook the World. Von Israel Rosenfield, Edward Ziff und Borin van Loon.

D. Summerer, 2011 .

Evolved sequence contexts for highly efficient amber suppression with noncanonical amino acids.

Moritz Pott, Moritz Johannes Schmidt, D. Summerer, 2014, ACS chemical biology.

Imaging-Based In Situ Analysis of 5-Methylcytosine at Low Repetitive Single Gene Loci with Transcription-Activator-Like Effector Probes

Benjamin C. Buchmuller, D. Summerer, Á. Muñoz‐López, 2023, ACS chemical biology.

Engineering DNA Backbone Interactions Results in TALE Scaffolds with Enhanced 5-Methylcytosine Selectivity

Preeti Rathi, D. Summerer, A. Witte, 2017, Scientific Reports.

Epigenetic chromatin modification by amber suppression technology.

H. Neumann, D. Summerer, Petra Neumann-Staubitz, 2018, Current opinion in chemical biology.

Substrates for Investigation of DNA Polymerase Function: Synthesis and Properties of 4′-C-Alkylated Oligonucleotides

A. Marx, D. Summerer, I. Detmer, 2003 .

DNA Polymerase Selectivity: Sugar Interactions Monitored with High-Fidelity Nucleotides This work was supported by a grant from the Deutsche Forschungsgemeinschaft. We thank Professor Dr. Michael Famulok for his continuing support.

A. Marx, D. Summerer, 2001, Angewandte Chemie.

Enhanced fidelity in mismatch extension by DNA polymerase through directed combinatorial enzyme design.

A. Marx, D. Summerer, I. Detmer, 2005, Angewandte Chemie.

A Need for Speed: Genetic Encoding of Rapid Cycloaddition Chemistries for Protein Labelling in Living Cells

D. Summerer, Daniel Summerer, Moritz J Schmidt, 2012, Chembiochem : a European journal of chemical biology.

Directed Evolution of Orthogonal Pyrrolysyl-tRNA Synthetases in Escherichia coli for the Genetic Encoding of Noncanonical Amino Acids.

D. Summerer, M. Schmidt, 2018, Methods in molecular biology.