H. Hilpert

发表

Mapping the conformational space accessible to BACE2 using surface mutants and cocrystals with Fab fragments, Fynomers and Xaperones.

D. Banner, A. Kuglstatter, J. Steyaert, 2013, Acta crystallographica. Section D, Biological crystallography.

Aleglitazar, a new, potent, and balanced dual PPARalpha/gamma agonist for the treatment of type II diabetes.

B. Kuhn, J. Benz, A. Ruf, 2009, Bioorganic & medicinal chemistry letters.

Structure-based design of indole propionic acids as novel PPARα/γ co-agonists

Hans Peter Märki, Jörg Benz, Bernd Kuhn, 2006 .

β-Secretase (BACE1) inhibitors with high in vivo efficacy suitable for clinical evaluation in Alzheimer's disease.

Wolfgang Guba, Harald Mauser, Mark Rogers-Evans, 2013, Journal of medicinal chemistry.

15N-NMR Spectroscopic Characterization of Triaziridines

H. Hilpert, R. Hollenstein, 1986 .

Geistliche bildung und laienbildung. Zur überlieferung der schulschrift Compendium historiae in genealogia Christi (Compendium veteris testamenti) des Petrus von Poitiers (1205) in England

H. Hilpert, 1985 .

Bace2 is a β cell-enriched protease that regulates pancreatic β cell function and mass.

R. Aebersold, M. Stoffel, H. Moch, 2011, Cell metabolism.

Mast cell chymase inhibition reduces atherosclerotic plaque progression and improves plaque stability in ApoE-/- mice.

T. V. van Berkel, I. Bot, H. Hilpert, 2011, Cardiovascular research.

Identification of potent and selective cathepsin S inhibitors containing different central cyclic scaffolds.

D. Banner, W. Haap, A. Kuglstatter, 2013, Journal of medicinal chemistry.

Novel versatile approach to an enantiopure 19-nor, des-C,D vitamin D3 derivative

H. Hilpert, B. Wirz, 2001 .

Synthesis of some mimics of nucleoside triphosphates

M. Peel, D. Coe, R. Storer, 1991 .

Efficient synthesis of novel NK1 receptor antagonists: selective 1,4-addition of grignard reagents to 6-chloronicotinic acid derivatives.

Michelangelo Scalone, Hans Hilpert, H. Hilpert, 2006, The Journal of organic chemistry.

Discovery of a factor Xa inhibitor (3R,4R)-1-(2,2-difluoro-ethyl)-pyrrolidine-3,4-dicarboxylic acid 3-[(5-chloro-pyridin-2-yl)-amide] 4-[[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenyl]-amide] as a clinical candidate.

Martin Stahl, Walter Huber, Jörg Benz, 2010, Bioorganic & medicinal chemistry letters.

Design and Biological Evaluation of Novel, Balanced Dual PPARα/γ Agonists

Armin Ruf, Jörg Benz, Daniel Schlatter, 2009, ChemMedChem.

Synthesis of the HIV-Proteinase Inhibitor Saquinavir: A Challenge for Process Research

H. Hilpert, W. Goehring, S. Gokhale, 1996, CHIMIA.

Triaziridines. Part 7. Stable Pyramidal Configurations at the Nitrogen Atoms of Dialkyl- and Trialkyl-triaziridines.

H. Hilpert, A. Dreiding, L. Hoesch, 1987 .

Reduktion von 1,2‐bis[(Z)‐(2‐nitrophenyl)‐NNO‐azoxy]benzol: Synthese von Cyclotrisazobenzol ( = (5E,6aZ,11E,12aZ,17E,18aZ)‐5,6,11,12,17,18‐Hexaazatribenzo[aei][1,3,5,7,9,11]cyclododeca‐hexaen)

H. Hilpert, A. Dreiding, L. Hoesch, 1985 .

The potential for using carbocyclic nucleosides for the treatment of AIDS. Part 1. Preparation of some analogues for azidothymidine (AZT)

R. Storer, H. Hilpert, S. Roberts, 1991 .

The Potential for Using Carbocyclic Nucleosides for the Treatment of AIDS. Part 1. Preparation of Some Analogues for Azidothymidine (AZT).

R. Storer, H. Hilpert, S. Roberts, 1991 .

Synthesis of 3-(2-Carboxy-4-pyridyl)- and 3-(6-Carboxy-3-pyridyl)-DL-alanine.

H. Hilpert, 1987 .

TOTAL SYNTHESIS OF BETALAINS

H. Hilpert, A. Dreiding, 1984 .

Dicer1–miR-328–Bace1 signalling controls brown adipose tissue differentiation and function

J. Mauer, M. Mori, P. Frommolt, 2016, Nature Cell Biology.

Combined Treatment with a BACE Inhibitor and Anti-Aβ Antibody Gantenerumab Enhances Amyloid Reduction in APPLondon Mice

L. Ozmen, H. Jacobsen, A. Tanghe, 2014, The Journal of Neuroscience.

Bisvertinols: a new group of dimeric vertinoids from verticillium intertextum

D. Rast, L. Trifonov, H. Hilpert, 1986 .

Structure-based design of indole propionic acids as novel PPARalpha/gamma co-agonists.

B. Kuhn, J. Benz, H. Hilpert, 2006, Bioorganic & Medicinal Chemistry Letters.

BACE1 inhibitors: a head group scan on a series of amides.

W. Guba, D. Banner, E. Pinard, 2013, Bioorganic & medicinal chemistry letters.

PRODUCTS OF THERMOLYSIS OF N-(1-PYRIDINIO)-2-NITROANILIDES ARE NOT TRIAZIRIDINES, BUT 1,2-BIS((2′-NITROPHENYL)AZOXY)BENZENES

H. Hilpert, A. Dreiding, L. Hoesch, 1982 .

Multiselective enzymatic reactions for the synthesis of protected homochiral cis- and trans-1,3,5-cyclohexanetriols

H. Iding, H. Hilpert, B. Wirz, 2000 .

Richard of Cornwall's candidature for the German throne and the christmas 1256 parliament at Westminster

H. Hilpert, 1980 .