P. van Galen

发表

Modelling the P2Y purinoceptor using rhodopsin as template.

K. Jacobson, A. V. van Rhee, B. Fischer, 1995, Drug design and discovery.

A1 adenosine-receptor antagonists activate chloride efflux from cystic fibrosis cells.

K. Jacobson, O. Eidelman, H. Pollard, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Correlation of binding affinities with non-bonded interaction energies of thrombin-inhibitor complexes.

P. Grootenhuis, P. van Galen, P J van Galen, 1995, Acta crystallographica. Section D, Biological crystallography.

Structure-activity relationships of N6-benzyladenosine-5'-uronamides as A3-selective adenosine agonists.

X. Ji, N. Melman, B. Fischer, 1994, Journal of medicinal chemistry.

Characterization of human striatal A2-adenosine receptors using radioligand binding and photoaffinity labeling.

K. Jacobson, G. Stiles, X. Ji, 1992, Journal of receptor research.

Influence of the molecular structure of N6-(omega-aminoalkyl)adenosines on adenosine receptor affinity and intrinsic activity.

A. IJzerman, P. van Galen, W. Soudijn, 1989, European journal of pharmacology.

1H-imidazo[4,5-c]quinolin-4-amines: novel non-xanthine adenosine antagonists.

A. IJzerman, P. van Galen, W. Soudijn, 1991, Journal of medicinal chemistry.

SYNTHESIS AND BIOLOGICAL ACTIVITY OF NOVEL 2-THIO DERIVATIVES OF ATP.

K. Jacobson, T. Hammarberg, P. van Galen, 1993, Nucleosides & nucleotides.

Synthesis and biological activity of N6-(p-sulfophenyl)alkyl and N6-sulfoalkyl derivatives of adenosine: water-soluble and peripherally selective adenosine agonists.

K. Jacobson, X. Ji, K. S. Lee, 1992, Journal of medicinal chemistry.

Cellular immune response to human cartilage glycoprotein-39 (HC gp-39)-derived peptides in rheumatoid arthritis and other inflammatory conditions.

T. Ottenhoff, F. Breedveld, K. V. van Meijgaarden, 2000, Rheumatology.

1-Aminoisoquinoline as benzamidine isoster in the design and synthesis of orally active thrombin inhibitors.

P. van Galen, C. V. van Boeckel, P J van Galen, 1999, Bioorganic & medicinal chemistry letters.

Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.

M. Williams, P. van Galen, K A Jacobson, 1992, Journal of medicinal chemistry.

Mapping the N6-region of the adenosine A1 receptor with computer graphics.

A. IJzerman, F. Leusen, P. van Galen, 1989, European journal of pharmacology.

Adenosine A1 and A2 receptors: Structure–function relationships

K. Jacobson, G. Stiles, P. van Galen, 1992, Medicinal research reviews.

A binding site model and structure-activity relationships for the rat A3 adenosine receptor.

K. Jacobson, A. IJzerman, G. Stiles, 1994, Molecular pharmacology.

Structure-activity relationships of 8-styrylxanthines as A2-selective adenosine antagonists.

K. Jacobson, A. V. van Bergen, Y. Karton, 1993, Journal of medicinal chemistry.

Stimulation by alkylxanthines of chloride efflux in CFPAC-1 cells does not involve A1 adenosine receptors.

K. Jacobson, O. Eidelman, H. Pollard, 1995, Biochemistry.

A model for the antagonist binding site on the adenosine A1 receptor, based on steric, electrostatic, and hydrophobic properties.

H. V. van Vlijmen, A. IJzerman, P. van Galen, 1990, Journal of medicinal chemistry.

Adenosine derivatives with N 6‐alkyl, ‐alkylamine or ‐alkyladenosine substituents as probes for the A1‐receptor

A. IJzerman, P. van Galen, W. Soudijn, 1987, FEBS letters.

Molecular modeling of adenosine receptors. I. The ligand binding site on the A1 receptor.

K. Jacobson, A. IJzerman, P. van Galen, 1992, Drug design and discovery.

Adenosine A1 receptor and ligand molecular modeling

K. Jacobson, A. IJzerman, N. Peet, 1993 .

Molecular modeling of adenosine receptors. The ligand binding site on the rat adenosine A2A receptor.

K. Jacobson, A. IJzerman, P. van Galen, 1994, European journal of pharmacology.

Molecular characterization of A1 and A2a adenosine receptors

K. Jacobson, G. Stiles, X. Ji, 1993 .

Xanthine-7-Ribosides as Adenosine Al Receptor Antagonists: Further Evidence for Adenosine's Anti Mode of Binding

Adriaan P. IJzerman, A. IJzerman, P. van Galen, 1990 .