A. Colson

发表

P2Y1 antagonists: combining receptor-based modeling and QSAR for a quantitative prediction of the biological activity based on consensus scoring.

K. Jacobson, T. K. Harden, I. Tikhonova, 2007, Journal of medicinal chemistry.

Interactions between Conserved Residues in Transmembrane Helices 1, 2, and 7 of the Thyrotropin-releasing Hormone Receptor*

Marvin C. Gershengorn, Wei Wang, Roman Osman, 1997, The Journal of Biological Chemistry.

1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors.

Thomas R Downs, Julie A Farmer, Gina S. Gerwe, 2006, Bioorganic & medicinal chemistry letters.

MCH-R1 antagonists based on an arginine scaffold: SAR studies on the amino-terminus.

D. Cross-Doersen, A. Colson, Daniel A Denton, 2007, Bioorganic & medicinal chemistry letters.

Synthesis and biological activity of novel peptide mimetics as melanocortin receptor agonists.

Xue‐Wei Liu, A. Colson, F. H. Ebetino, 2008, Bioorganic & medicinal chemistry letters.

Ab initio molecular orbital calculations on DNA radical ions. 4. Effect of hydration on electron affinities and ionization potentials of base pairs

M. Sevilla, A. Colson, B. Besler, 1993 .

Comment on "Electron Attachment to Uracil.Theoretical ab Initio Study"

M. Sevilla, A. Colson, B. Besler, 1994 .

Static and dynamic roles of extracellular loops in G-protein-coupled receptors: a mechanism for sequential binding of thyrotropin-releasing hormone to its receptor.

A. Smolyar, R. Osman, M. Gershengorn, 1998, Biophysical journal.

Brivaracetam-induced elevation of carbamazepine epoxide levels: A post-hoc analysis from the clinical development program

M. Brodie, T. Fakhoury, A. Colson, 2018, Epilepsy Research.

Thyrotropin-releasing hormone analogs.

M. Gershengorn, A. Colson, 2006, Mini reviews in medicinal chemistry.

Ab initio molecular orbital calculations on DNA base pair radical ions: effect of base pairing on proton-transfer energies, electron affinities, and ionization potentials

M. Sevilla, A. Colson, B. Besler, 1992 .

Regio- and stereo-controlled copper organometallic addition to a piperidinyl aziridine: synthesis of trans 3-amino-4-alkyl-piperidines

A. Colson, B. Ledoussal, X. Hu, 2002 .

Solid-supported synthesis of putative peptide beta-turn mimetics via Ugi reaction for diketopiperazine formation.

A. Colson, A. Gołębiowski, S. R. Klopfenstein, 2002, Journal of combinatorial chemistry.

Chapter 7 – Application of Molecular Orbital Theory to the Elucidation of Radical Processes Induced by Radiation Damage to DNA

A. Colson, 1999 .

Reactions of sulfhydryl and sulfide radicals with oxygen, hydrogen sulfide, hydrosulfide, and sulfide: formation of SO2-, HSSH-, HSS.2- and HSS.

M. Sevilla, A. Colson, K. Petit, 1991 .

Elucidation of primary radiation damage in DNA through application of ab initio molecular orbital theory.

M. Sevilla, A. Colson, 1995, International journal of radiation biology.

Structure and Relative Stability of Deoxyribose Radicals in a Model DNA Backbone: Ab Initio Molecular Orbital Calculations

M. Sevilla, A. Colson, 1995 .

Design and synthesis of potent, non-peptidic inhibitors of HPTPbeta.

Gina S. Gerwe, K. Peters, A. Colson, 2006, Bioorganic & medicinal chemistry letters.

Understanding the structural and functional differences between mouse thyrotropin‐releasing hormone receptors 1 and 2

B. Raaka, F. Deflorian, M. Gershengorn, 2008, Proteins.

Role of the extracellular loops of the thyrotropin-releasing hormone receptor: evidence for an initial interaction with thyrotropin-releasing hormone.

R. Osman, M. Gershengorn, B. Czyzewski, 1997, Biochemistry.

Ab initio molecular orbital calculations of DNA radical ions. 5. Scaling of calculated electron affinities and ionization potentials to experimental values

M. Sevilla, A. Colson, B. Besler, 1995 .

Identification of substituted 4-aminopiperidines and 3-aminopyrrolidines as potent MCH-R1 antagonists for the treatment of obesity.

O. Reizes, A. Colson, Jan R Davis, 2006, Bioorganic & medicinal chemistry letters.

Evaluation of small-molecule modulators of the luteinizing hormone/choriogonadotropin and thyroid stimulating hormone receptors: structure-activity relationships and selective binding patterns.

Gerd Krause, Stefano Costanzi, Susanne Neumann, 2006, Journal of medicinal chemistry.

Solid-Supported Synthesis of a Peptide β-Turn Mimetic

X. Shao, A. Colson, A. Gołębiowski, 2000 .

A hydrophobic cluster between transmembrane helices 5 and 6 constrains the thyrotropin-releasing hormone receptor in an inactive conformation.

R. Osman, M. Gershengorn, A. Colson, 1998, Molecular pharmacology.

A virtual screen for diverse ligands: discovery of selective G protein-coupled receptor antagonists.

Stefano Costanzi, Susanne Neumann, J. Deschamps, 2008, Journal of the American Chemical Society.

A Low Molecular Weight Agonist Signals by Binding to the Transmembrane Domain of Thyroid-stimulating Hormone Receptor (TSHR) and Luteinizing Hormone/Chorionic Gonadotropin Receptor (LHCGR)*

R. Paschke, B. Raaka, G. Krause, 2006, Journal of Biological Chemistry.

Ab initio molecular orbital calculations of DNA bases and their radical ions in various protonation states: evidence for proton transfer in GC base pair radical anions

M. Sevilla, A. Colson, Michael D. Sevilla, 1992 .

Discovery of orally bioavailable 1,3,4-trisubstituted 2-oxopiperazine-based melanocortin-4 receptor agonists as potential antiobesity agents.

Julie A Farmer, M. Dowty, C. Obringer, 2008, Journal of medicinal chemistry.

Ab initio molecular orbital calculations on DNA radical ions. 3. Ionization potentials and ionization sites in components of the DNA sugar phosphate backbone

M. Sevilla, A. Colson, B. Besler, 1993 .

Ab Initio Molecular Orbital Calculations of Radicals Formed by H.bul. and .bul.OH Addition to the DNA Bases: Electron Affinities and Ionization Potentials

M. Sevilla, A. Colson, 1995 .

The efficacy and cardiac evaluation of aminomethyl tetrahydronaphthalene ketopiperazines: a novel class of potent MCH-R1 antagonists.

M. Dowty, O. Reizes, C. Obringer, 2007, Bioorganic & medicinal chemistry.

Novel pyrazolopiperazinone- and pyrrolopiperazinone-based MCH-R1 antagonists.

M. Dowty, O. Reizes, C. Obringer, 2007, Bioorganic & medicinal chemistry letters.

Aminomethyl tetrahydronaphthalene ketopiperazine MCH-R1 antagonists--Increasing selectivity over hERG.

M. Dowty, O. Reizes, C. Obringer, 2007, Bioorganic & medicinal chemistry letters.