M. G. Chini

发表

Molecular mechanism of tanshinone IIA and cryptotanshinone in platelet anti-aggregating effects: an integrated study of pharmacology and computational analysis.

G. Bifulco, F. Maione, V. Cantone, 2015, Fitoterapia.

Structure-based discovery of inhibitors of microsomal prostaglandin E2 synthase-1, 5-lipoxygenase and 5-lipoxygenase-activating protein: promising hits for the development of new anti-inflammatory agents.

G. Bifulco, O. Werz, R. Riccio, 2011, Journal of medicinal chemistry.

Design and synthesis of a second series of triazole-based compounds as potent dual mPGES-1 and 5-lipoxygenase inhibitors.

G. Bifulco, O. Werz, R. Riccio, 2012, European journal of medicinal chemistry.

4-Methylenesterols from Theonella swinhoei sponge are natural pregnane-X-receptor agonists and farnesoid-X-receptor antagonists that modulate innate immunity

G. Bifulco, A. Zampella, S. Fiorucci, 2012, Steroids.

Conicasterol E, a small heterodimer partner sparing farnesoid X receptor modulator endowed with a pregnane X receptor agonistic activity, from the marine sponge Theonella swinhoei.

G. Bifulco, V. Sepe, A. Zampella, 2012, Journal of medicinal chemistry.

Preliminary Structure-Activity Relationship on Theonellasterol, a New Chemotype of FXR Antagonist, from the Marine Sponge Theonella swinhoei

G. Bifulco, V. Sepe, A. Zampella, 2012, Marine drugs.

Biological Profile of Two Gentiana lutea L. Metabolites Using Computational Approaches and In Vitro Tests

G. Bifulco, C. Finamore, G. Saviano, 2021, Biomolecules.

Glucopyranosylbianthrones from the Algerian Asphodelus tenuifolius: Structural Insights and Biological Evaluation on Melanoma Cancer Cells.

G. Bifulco, S. Terracciano, I. Bruno, 2018, Journal of natural products.

Molecular insights into azumamide e histone deacetylases inhibitory activity.

G. Bifulco, R. Riccio, I. Izzo, 2007, Journal of the American Chemical Society.

Addressing the Target Identification and Accelerating the Repositioning of Anti‐Inflammatory/Anti‐Cancer Organic Compounds by Computational Approaches

G. Bifulco, G. Lauro, M. G. Chini, 2021 .

Elucidating heteroatom influence on homonuclear 4J(H,H) coupling constants by DFT/NMR approach

G. Bifulco, P. Dambruoso, R. Riccio, 2019, Magnetic resonance in chemistry : MRC.

Guaianolides from Ormenis mixta: Structural Insights and Evaluation of Their Anti-inflammatory Profile

G. Bifulco, N. de Tommasi, A. Kabouche, 2019, Planta Medica.

Identification of Limonol Derivatives as Heat Shock Protein 90 (Hsp90) Inhibitors through a Multidisciplinary Approach.

G. Bifulco, S. Castellano, C. Milite, 2016, Chemistry.

Dimeric and trimeric triazole based molecules as a new class of Hsp90 molecular chaperone inhibitors.

G. Bifulco, R. Riccio, S. Terracciano, 2013, European journal of medicinal chemistry.

Design, Synthesis, and Biological Activity of Hydroxamic Tertiary Amines as Histone Deacetylase Inhibitors

G. Bifulco, R. Riccio, S. Terracciano, 2012, ChemMedChem.

Thiazolidin-4-one-based compounds interfere with the eicosanoid biosynthesis pathways by mPGES-1/sEH/5-LO multi-target inhibition

G. Bifulco, O. Werz, V. Sepe, 2022, European Journal of Medicinal Chemistry Reports.

Targeting the Hsp90 C-terminal domain by the chemically accessible dihydropyrimidinone scaffold.

G. Bifulco, R. Riccio, S. Terracciano, 2015, Chemical communications.

Cytotoxic Sesquiterpenoids from Ammoides atlantica Aerial Parts

G. Bifulco, M. De Leo, N. de Tommasi, 2022, Journal of natural products.

New dihydropyrimidin-2(1H)-one based Hsp90 C-terminal inhibitors

G. Bifulco, R. Riccio, C. Saturnino, 2016 .

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

Simona De Vita, Gianluigi Lauro, Maria Giovanna Chini, 2020, RSC advances.

Discovery of new molecular entities able to strongly interfere with Hsp90 C-terminal domain

G. Bifulco, R. Riccio, S. Terracciano, 2018, Scientific Reports.

Targeting mPGES-1 by a Combinatorial Approach: Identification of the Aminobenzothiazole Scaffold to Suppress PGE2 Levels.

G. Bifulco, O. Werz, A. Koeberle, 2020, ACS medicinal chemistry letters.

Synthesis, biological evaluation, and molecular docking of Ugi products containing a zinc-chelating moiety as novel inhibitors of histone deacetylases.

G. Bifulco, P. Canonico, G. Tron, 2009, Journal of medicinal chemistry.

Synthesis of new mono and bis amides projected as potential histone deacetylase (HDAC) inhibitors

G. Bifulco, R. Riccio, S. Terracciano, 2010 .

Limonoids from Guarea guidonia and Cedrela odorata: Heat Shock Protein 90 (Hsp90) Modulator Properties of Chisomicine D

G. Bifulco, F. Dal Piaz, N. de Tommasi, 2021, Journal of natural products.

Pharmacological and molecular docking assessment of cryptotanshinone as natural-derived analgesic compound

G. Bifulco, A. Saviano, S. Laneri, 2020, Biomedicine & Pharmacotherapy.

Phytochemical Analysis of the Methanolic Extract and Essential Oil from Leaves of Industrial Hemp Futura 75 Cultivar: Isolation of a New Cannabinoid Derivative and Biological Profile Using Computational Approaches

G. Bifulco, C. Finamore, G. Saviano, 2022, Plants.

Repositioning of Quinazolinedione-Based Compounds on Soluble Epoxide Hydrolase (sEH) through 3D Structure-Based Pharmacophore Model-Driven Investigation

Maria T. Potenza, G. Bifulco, O. Werz, 2022, Molecules.

Diterpenoid Constituents of Psiadiapunctulata and Evaluation of Their Antimicrobial Activity

G. Bifulco, A. Bisio, G. Donadio, 2022, Journal of natural products.

Carnosol Attenuates LPS-Induced Inflammation of Cardiomyoblasts by Inhibiting NF-κB: A Mechanistic in Vitro and in Silico Study

G. Bifulco, A. Saviano, F. Maione, 2022, Evidence-based complementary and alternative medicine : eCAM.

Conformationally locked calixarene-based histone deacetylase inhibitors.

G. Bifulco, C. Gaeta, P. Neri, 2010, Organic letters.

Fibril aggregation inhibitory activity of the β‐sheet breaker peptides: a molecular docking approach

G. Bifulco, M. Scrima, A. D'Ursi, 2009, Journal of peptide science : an official publication of the European Peptide Society.

Identification of 2,4,5-trisubstituted-2,4-dihydro-3H-1,2,4-triazol-3-one-based small molecules as selective BRD9 binders.

G. Bifulco, S. Terracciano, I. Bruno, 2022, European journal of medicinal chemistry.

Diterpenoids from Zhumeria majdae roots as potential heat shock protein 90 (HSP90) modulators.

G. Bifulco, N. de Tommasi, M. G. Chini, 2021, Phytochemistry.

Identification and mechanism of action analysis of the new PARP-1 inhibitor 2″-hydroxygenkwanol A.

G. Bifulco, A. Tosco, F. Dal Piaz, 2015, Biochimica et biophysica acta.

Computational NMR Methods in the Stereochemical Analysis of Organic Compounds: Are Proton or Carbon NMR Chemical Shift Data More Discriminating?

G. Bifulco, R. Riccio, M. G. Chini, 2015 .

Natural Iminosugar (+)-Lentiginosine Inhibits ATPase and Chaperone Activity of Hsp90

G. Bifulco, C. Pisano, F. Dal Piaz, 2012, PloS one.

Quantum Mechanical Calculation of NMR Parameters in the Stereostructural Determination of Natural Products

G. Bifulco, R. Riccio, M. G. Chini, 2010 .

Anti‐inflammatory and analgesic activity of carnosol and carnosic acid in vivo and in vitro and in silico analysis of their target interactions

G. Bifulco, O. Werz, A. Koeberle, 2017, British journal of pharmacology.

A chemical-biological study reveals C9-type iridoids as novel heat shock protein 90 (Hsp90) inhibitors.

G. Bifulco, R. Cotugno, C. Pisano, 2013, Journal of medicinal chemistry.