Hui Chen

发表

Design, synthesis, and biological evaluation of 2-(phenoxyaryl)-3-urea derivatives as novel P2Y1 receptor antagonists.

Hong Liu, Huaiyu Yang, Jingjing Peng, 2018, European journal of medicinal chemistry.

Rational design of 4,5-disubstituted-5,7-dihydro-pyrrolo[2,3-d]pyrimidin-6-ones as a novel class of inhibitors of epidermal growth factor receptor (EGF-R) and Her2(p185(erbB)) tyrosine kinases.

C. Liang, Hui Chen, Li Sun, 2002, Bioorganic & medicinal chemistry letters.

Design, Synthesis, and Pharmacological Evaluation of Novel Multisubstituted Pyridin-3-amine Derivatives as Multitargeted Protein Kinase Inhibitors for the Treatment of Non-Small Cell Lung Cancer.

Hong Liu, M. Zheng, M. Geng, 2017, Journal of medicinal chemistry.

Design, synthesis and biological evaluation of 6-deoxy O-spiroketal C-arylglucosides as novel renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes.

Hong Liu, Jiang Wang, Jingya Li, 2019, European journal of medicinal chemistry.

Arylamino containing hydroxamic acids as potent urease inhibitors for the treatment of Helicobacter pylori infection.

Shen-Zhen Ren, Hui Chen, Weiwei Ni, 2018, European journal of medicinal chemistry.

Heme synthesis increases artemisinin-induced radical formation and cytotoxicity that can be suppressed by superoxide scavengers.

G. Gerhard, Hui Chen, Shiming Zhang, 2010, Chemico-biological interactions.

The Secretome Engages STAT3 to Favor a Cytokine-rich Microenvironment in Mediating Acquired Resistance to FGFR Inhibitors

Yi Chen, Jian Ding, M. Geng, 2018, Molecular Cancer Therapeutics.

c-Myc Alteration Determines the Therapeutic Response to FGFR Inhibitors

Min Huang, Yi Chen, Jian Ding, 2016, Clinical Cancer Research.

Discovery of novel Ponatinib analogues for reducing KDR activity as potent FGFRs inhibitors.

Youhong Hu, M. Geng, Dong Lu, 2017, European journal of medicinal chemistry.

Discovery of 5-[5-fluoro-2-oxo-1,2- dihydroindol-(3Z)-ylidenemethyl]-2,4- dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide, a novel tyrosine kinase inhibitor targeting vascular endothelial and platelet-derived growth factor receptor tyrosine kinase.

Hui Chen, Chris Liang, C. Liang, 2003, Journal of medicinal chemistry.

N-benzylpiperidinol derivatives as novel USP7 inhibitors: Structure-activity relationships and X-ray crystallographic studies.

Jun O. Liu, Hongbin Sun, Hui Chen, 2020, European journal of medicinal chemistry.

Evaluation of in vitro and in vivo activity of a multityrosine kinase inhibitor, AL3810, against human thyroid cancer

Yi Chen, Jian Ding, M. Geng, 2017, Acta Pharmacologica Sinica.

A Selective and Oral Small Molecule Inhibitor of Vascular Epithelial Growth Factor Receptor (VEGFR)-2 and VEGFR-1 Inhibits Neovascularization and Vascular Permeability

A. Howlett, G. Mcmahon, Qingling Zhang, 2003, Journal of Pharmacology and Experimental Therapeutics.

Unraveling the genetic causes in large pedigrees with gout by whole-exome sequencing

Hui Chen, Linhua Zhang, Xiaoru Xia, 2020, International journal of molecular medicine.

Whole-Exome Sequencing Reveals a Rare Missense Variant in SLC16A9 in a Pedigree with Early-Onset Gout

M. Brown, Hui Chen, Linhua Zhang, 2020, BioMed research international.